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https://www.readbyqxmd.com/read/29786762/chronic-conditions-and-multimorbidity-in-a-primary-care-population-a-study-in-the-swiss-sentinel-surveillance-network-sentinella
#1
Markus Gnädinger, Lilli Herzig, Alessandro Ceschi, Dieter Conen, Alfred Staehelin, Marco Zoller, Milo A Puhan
OBJECTIVES: To provide estimates of the prevalence of chronic conditions in Swiss primary care. METHODS: In total, 175 general practitioners (GP) or pediatricians (PED) reporting to the Swiss Sentinel Surveillance Network collected morbidity data. RESULTS: In 26,853 patient contacts, mean (± SD) age was 55.8 ± 21.6 or 6.1 ± 5.7 years (in GPs vs. PEDs, respectively) and 47% were males. In GP patients, median Thurgau Morbidity Index was 2 (IQR 1-3)...
May 21, 2018: International Journal of Public Health
https://www.readbyqxmd.com/read/29786065/real-time-precise-point-positioning-based-zenith-tropospheric-delay-for-precipitation-forecasting
#2
Qingzhi Zhao, Yibin Yao, Wanqiang Yao, Zufeng Li
GPS-based Zenith Tropospheric Delay (ZTD) estimation should be easily obtained in a cost-effective way, however, the most previous studies focus on post-processed ZTD estimates using satellite orbit and clock products with at least 3-9 hours latency provided by International GNSS Service (IGS), which limits the GNSS meteorological application for nowcasting. With the development of IGS's real-time pilot project (RTPP), this limitation was removed by April, 2013 as real-time satellite orbit and clock products can be obtained on-line...
May 21, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29784021/the-difficult-conversation-a-qualitative-evaluation-of-the-eat-well-move-more-family-weight-management-service
#3
Rebecca E Johnson, Oyinlola Oyebode, Sadie Walker, Elizabeth Knowles, Wendy Robertson
OBJECTIVE: The Eat Well Move More (EWMM) family and child weight management service is a 12-week intervention integrating healthy eating and physical activity education and activities for families and children aged 4-16. EWMM service providers identified low uptake 12 months prior to the evaluation. The aims of this study were to describe referral practices and pathways into the service to identify potential reasons for low referral and uptake rates. RESULTS: We conducted interviews and focus groups with general practitioners (GPs) (n = 4), school nurses, and nursing assistants (n = 12)...
May 21, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29782150/-site-and-mutation-specific-predictions-enable-minimal-directed-evolution-libraries
#4
Jeffrey C Moore, Agustina Rodriguez-Granillo, Alejandro Crespo, Sridhar Govindarajan, Mark Welch, Kaori Hiraga, Katrina Lexa, Nicholas Marshall, Matthew David Truppo
Directed evolution experiments designed to improve the activity of a biocatalyst have increased in sophistication from the early days of completely random mutagenesis. Sequence-based and structure-based methods have been developed to identify "hotspot" positions that when randomized provide a higher frequency of beneficial mutations that improve activity. These focused mutagenesis methods reduce library sizes and therefore reduce screening burden, accelerating the rate of finding improved enzymes...
May 21, 2018: ACS Synthetic Biology
https://www.readbyqxmd.com/read/29780265/does-focused-and-dedicated-teaching-improve-the-confidence-of-gp-trainees-to-diagnose-and-manage-common-acute-ent-pathologies-in-primary-care
#5
Vikas Acharya, Matthew Haywood, Naomi Kokkinos, Anisha Raithatha, Sinthuja Francis, Rishi Sharma
Background: General practitioners (GPs) are key members of the health care profession who are required to have a considerable breadth of knowledge to manage and treat patients effectively in the community. Their skills and experience varies depending on the medical school they attended and their foundation training and specialist GP training schemes. Exposure to ear, nose, and throat (ENT)-specific pathology is often insufficient due to the lack of formal otolaryngology rotations, minimal relevant teaching opportunities, and inconsistencies in curricula, despite ENT-related pathology presentations being one of the commonest consultations in primary care...
2018: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/29779948/the-eukaryotic-proteome-is-shaped-by-e3-ubiquitin-ligases-targeting-c-terminal-degrons
#6
Itay Koren, Richard T Timms, Tomasz Kula, Qikai Xu, Mamie Z Li, Stephen J Elledge
Degrons are minimal elements that mediate the interaction of proteins with degradation machineries to promote proteolysis. Despite their central role in proteostasis, the number of known degrons remains small, and a facile technology to characterize them is lacking. Using a strategy combining global protein stability (GPS) profiling with a synthetic human peptidome, we identify thousands of peptides containing degron activity. Employing CRISPR screening, we establish that the stability of many proteins is regulated through degrons located at their C terminus...
May 11, 2018: Cell
https://www.readbyqxmd.com/read/29779300/coroners-recommendations-for-prevention-of-resident-deaths-in-aged-care-the-role-of-primary-care-providers
#7
Georgia Aitken, Athena Demosthenous, Lyndal Bugeja, Melissa Willoughby, Carmel Young, Joseph E Ibrahim
BACKGROUND AND OBJECTIVES: Currently, very little is known about how coroners consider a role for general practitioners (GPs) and registered nurses (RNs) in recommendations for the prevention of premature death. Involving these professions in recommendations generally directed towards government organisations or residential aged care providers and management may contribute to more successful broader policy changes. The aim of this article was to examine whether coroners' recommendations describe a specific role for GPs and RNs in the prevention of premature death in residential aged care settings and, if so, what domains of practice were considered...
May 2018: Australian journal of general practice
https://www.readbyqxmd.com/read/29779298/how-common-is-multiple-general-practice-attendance-in-australia
#8
Michael Wright, Jane Hall, Kees van Gool, Marion Haas
BACKGROUND AND OBJECTIVES: Australians can seek general practice care from multiple general practitioners (GPs) in multiple locations. This provides high levels of patient choice but may reduce continuity of care. The aim of this study was to estimate the prevalence of attendance at multiple general practices in Australia, and identify patient characteristics associated with multiple practice attendances. METHOD: A cross-sectional survey of 2477 Australian adults was conducted online in July 2013...
May 2018: Australian journal of general practice
https://www.readbyqxmd.com/read/29779292/paediatric-constipation-an-approach-and-evidence-based-treatment-regimen
#9
Harveen Singh, Frances Connor
BACKGROUND: Constipation affects 5-30% of children and is responsible for 3% of primary care visits. General practitioners (GPs) are frequently the first medical encounter for concerned parents regarding their child's bowel habit. OBJECTIVE: The aim of this article is to review the assessment and management of children with constipation to empower GPs to initiate treatment and know when to refer to a paediatrician. DISCUSSION: In the absence of organic aetiology, childhood constipation is almost always functional and often due to painful bowel movements that prompt the child to withhold stool...
May 2018: Australian journal of general practice
https://www.readbyqxmd.com/read/29776442/multimorbidity-can-general-practitioners-identify-the-health-conditions-most-important-to-their-patients-results-from-a-national-cross-sectional-study-in-switzerland
#10
Anouk Déruaz-Luyet, Alexandra A N'Goran, Jérôme Pasquier, Bernard Burnand, Patrick Bodenmann, Stefan Zechmann, Stefan Neuner-Jehle, Nicolas Senn, Daniel Widmer, Sven Streit, Andreas Zeller, Dagmar M Haller, Lilli Herzig
BACKGROUND: Faced with patients suffering from more than one chronic condition, or multimorbidity, general practitioners (GPs) must establish diagnostic and treatment priorities. Patients also set their own priorities to handle the everyday burdens associated with their multimorbidity and these may be different from the priorities established by their GP. A shared patient-GP agenda, driven by knowledge of each other's priorities, would seem central to managing patients with multimorbidity...
May 17, 2018: BMC Family Practice
https://www.readbyqxmd.com/read/29774712/-diagnostic-imaging-procedures-and-prescribing-appropriateness-are-administrative-data-a-proper-instrument-an-experience-from-piedmont-region-northern-italy
#11
Eva Pagano, Laura Crosetto, Andrea Evangelista, Chiara Monagheddu, Ottavio Davini, Giulio Fornero, Ida Raciti, Guido Giustetto, Giovannino Ciccone
OBJECTIVES: to assess at population level if healthcare administrative data can be suitable to identify variability and determinants of the prescribing rates for some diagnostic imaging procedures at high-risk of inappropriateness. DESIGN: population-based observational study. SETTING AND PARTICIPANTS: Piedmont Region (Northern Italy) adult population (>20 years) in year 2013. The subjects included were 3,566,147, referring to 3,016 general practitioners (GPs), in 12 Local Health Authorities (LHAs)...
March 2018: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/29774296/integrated-risk-mapping-and-landscape-characterisation-of-lymphatic-filariasis-and-loiasis-in-south-west-nigeria
#12
Tara A Brant, Patricia N Okorie, Olushola Ogunmola, Nureni Bolaji Ojeyode, S B Fatunade, Emmanuel Davies, Yisa Saka, Michelle C Stanton, David H Molyneux, J Russell Stothard, Louise A Kelly-Hope
Nigeria has the heaviest burden of lymphatic filariasis (LF) in sub-Saharan Africa, which is caused by the parasite Wuchereria bancrofti and transmitted by Anopheles mosquitoes. LF is targeted for elimination and the national programme is scaling up mass drug administration (MDA) across the country to interrupt transmission. However, in some regions the co-endemicity of the filarial parasite Loa loa (loiasis) is an impediment due to the risk of severe adverse events (SAEs) associated with the drug ivermectin...
February 2018: Parasite Epidemiology and Control
https://www.readbyqxmd.com/read/29774228/open-path-dual-comb-spectroscopy-to-an-airborne-retroreflector
#13
Kevin C Cossel, Eleanor M Waxman, Fabrizio R Giorgetta, Michael Cermak, Ian R Coddington, Daniel Hesselius, Shalom Ruben, William C Swann, Gar-Wing Truong, Gregory B Rieker, Nathan R Newbury
We demonstrate a new technique for spatial mapping of multiple atmospheric gas species. This system is based on high-precision dual-comb spectroscopy to a retroreflector mounted on a flying multi-copter. We measure the atmospheric absorption over long open-air paths to the multi-copter with comb-tooth resolution over 1.57 to 1.66 pm, covering absorption bands of CO2 , Cm, H2 O and isotopologues. When combined with GPS-based path length measurements, a fit of the absorption spectra retrieves the dry mixing ratios versus position...
July 20, 2017: Optica
https://www.readbyqxmd.com/read/29772701/speed-consistency-in-the-smart-tachograph
#14
Daniele Borio, Eduardo Cano, Gianmarco Baldini
In the transportation sector, safety risks can be significantly reduced by monitoring the behaviour of drivers and by discouraging possible misconducts that entail fatigue and can increase the possibility of accidents. The Smart Tachograph (ST), the new revision of the Digital Tachograph (DT), has been designed with this purpose: to verify that speed limits and compulsory rest periods are respected by drivers. In order to operate properly, the ST periodically checks the consistency of data from different sensors, which can be potentially manipulated to avoid the monitoring of the driver behaviour...
May 16, 2018: Sensors
https://www.readbyqxmd.com/read/29770474/improving-medication-safety-for-home-nursing-clients-a-prospective-observational-study-of-a-novel-clinical-pharmacy-service-the-visiting-pharmacist-vip-study
#15
C Y Lee, C Beanland, D Goeman, N Petrie, B Petrie, F Vise, J Gray, R A Elliott
WHAT IS KNOWN AND OBJECTIVE: Polypharmacy, medication errors and adverse events are common in older people receiving home nursing medication management support. Access to clinical pharmacists is limited. In Australia, few home nursing clients receive a general practitioner (GP)-initiated pharmacist-led Home Medicines Review, despite their eligibility and community nurses' (CN) efforts to facilitate this. An integrated home nursing clinical pharmacy service, in which CNs directly referred clients to a pharmacist, was therefore developed and piloted...
May 16, 2018: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/29769813/paediatric-vision-screening-in-the-primary-care-setting-in-ontario
#16
Tran D Le, Rana Arham Raashid, Linda Colpa, Jason Noble, Asim Ali, Agnes Wong
Objectives: Early intervention is critical to prevent treatable causes of vision loss in children. The objectives of the current study are: (1) to assess how well primary care physicians in Ontario follow the vision screening guidelines for children as recommended by the Canadian Paediatric Society and the Rourke Baby Record and (2) to identify barriers to vision screening in the primary care setting. Design: Cross-sectional survey. Methods: A 19-question survey was mailed out to 1000 randomly selected family physicians (family MDs), 1000 general practitioners (GPs) and 1000 paediatricians in Ontario as listed in the 2013 Canadian Medical Directory...
May 2018: Paediatrics & Child Health
https://www.readbyqxmd.com/read/29769778/a-new-classification-of-early-female-pattern-hair-loss
#17
Akiko Kaneko, Tsuyoshi Kaneko
Background: Global photographs (GPs) have been widely used to grade the severity in female pattern hair loss (FPHL). However, existing classifications for FPHL are not useful in the evaluation of early FPHL. Although there are some variations in early FPHL, even to a mild degree, all types of early FPHL are included in just one category. Therefore, the authors have devised a grading system for early FPHL with five levels focusing on the changes revealed by the surface reflected light of flash generated on GPs...
March 2018: International Journal of Trichology
https://www.readbyqxmd.com/read/29769025/use-of-diagnostic-tests-and-the-appropriateness-of-the-treatment-decision-in-patients-with-suspected-urinary-tract-infection-in-primary-care-in-denmark-observational-study
#18
Gloria Córdoba, Anne Holm, Tina Møller Sørensen, Volkert Siersma, Håkon Sandholdt, Marjukka Makela, Niels Frimodt-Møller, Lars Bjerrum
BACKGROUND: Inappropriate prescription of antibiotics is the leading driver of antimicrobial resistance (AMR). The majority of antibiotics are prescribed in primary care. Understanding how general practitioners (GPs) use diagnostic tests and the effect on treatment decision under daily practice conditions is important to reduce inappropriate prescription of antibiotics. The aim of the study was to investigate the use of diagnostic tests in primary care patients with suspected urinary tract infection (UTI) and to assess the appropriateness of the treatment decision (TD) under daily practice conditions in Denmark...
May 16, 2018: BMC Family Practice
https://www.readbyqxmd.com/read/29766615/barriers-and-facilitators-to-smoking-cessation-in-pregnancy-and-in-the-post-partum-period-the-health-care-professionals-perspective
#19
Felix Naughton, Sarah Hopewell, Lesley Sinclair, Dorothy McCaughan, Jennifer McKell, Linda Bauld
OBJECTIVES: Health care professionals and the health care environment play a central role in protecting pregnant and post-partum women and their infants from smoking-related harms. This study aimed to better understand the health professional's perspective on how interactions between women, health care professionals, and the environment influence how smoking is managed. DESIGN: Semi-structured interviews and focus groups. METHODS: Data were from 48 health care staff involved in antenatal or post-partum care at two UK sites, including midwives, obstetricians, health visitors, GPs, pharmacists, service commissioners, and Stop Smoking Service (SSS) advisors and managers...
May 15, 2018: British Journal of Health Psychology
https://www.readbyqxmd.com/read/29764915/remote-physiological-monitoring-in-an-austere-environment-a-future-for-battlefield-care-provision
#20
Matthew J Smyth, J A Round, A J Mellor
Wearable technologies are making considerable advances into the mainstream as they become smaller and more user friendly. The global market for such devices is forecasted to be worth over US$5 billion in 2018, with one in six people owning a device. Many professional sporting teams use self-monitoring to assess physiological parameters and work rate on the pitch, highlighting the potential utility for military command chains. As size of device reduces and sensitivity improves, coupled with remote connectivity technology, integration into the military environment could be relatively seamless...
May 14, 2018: Journal of the Royal Army Medical Corps
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