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Blood tests for heavy metals

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https://www.readbyqxmd.com/read/29884149/assessment-of-blood-levels-of-heavy-metals-including-lead-and-manganese-in-healthy-children-living-in-the-katanga-settlement-of-kampala-uganda
#1
Sarah E Cusick, Ericka G Jaramillo, Emily C Moody, Andrew S Ssemata, Doreen Bitwayi, Troy C Lund, Ezekiel Mupere
BACKGROUND: Exposure to environmental heavy metals is common among African children. Although many of these metals are known neurotoxicants, to date, monitoring of this exposure is limited, even in countries such as Uganda that are undergoing rapid industrialization. An assessment of the burden and potential causes of metal exposure is a critical first step in gauging the public health burden of metal exposure and in guiding its elimination. METHODS: In May 2016, we enrolled 100 children between the ages of 6 and 59 months living in the Katanga urban settlement of Kampala, Uganda...
June 8, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29696494/heavy-metal-exposure-has-adverse-effects-on-the-growth-and-development-of-preschool-children
#2
Xiang Zeng, Xijin Xu, Qilin Qin, Kai Ye, Weidong Wu, Xia Huo
The purpose of this study was to investigate the associations between levels of lead (Pb), cadmium (Cd), chromium (Cr), and manganese (Mn) in the PM2.5 and blood and physical growth, and development parameters including birth length and weight, height, weight, body mass index (BMI), head circumference, and chest circumference in preschool children from Guiyu (e-waste exposure area) and Haojiang (the reference area). A total of 470 preschool children from Guiyu and Haojiang located in southeast coast of China were recruited and required to undergo physical examination and blood tests during the study period...
April 25, 2018: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/29625400/spirulina-platensis-attenuates-the-associated-neurobehavioral-and-inflammatory-response-impairments-in-rats-exposed-to-lead-acetate
#3
Samah R Khalil, Hesham A Khalifa, Sabry M Abdel-Motal, Hesham H Mohammed, Yaser H A Elewa, Hend Atta Mahmoud
Heavy metals are well known as environmental pollutants with hazardous impacts on human and animal health because of their wide industrial usage. In the present study, the role of Spirulina platensis in reversing the oxidative stress-mediated brain injury elicited by lead acetate exposure was evaluated. In order to accomplish this aim, rats were orally administered with 300 mg/kg bw Spirulina for 15 d, before and simultaneously with an intraperitoneal injection of 50 mg/kg bw lead acetate [6 injections through the two weeks]...
August 15, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29520725/antimony-induced-neurobehavioral-and-biochemical-perturbations-in-mice
#4
Tanzina Tanu, Adiba Anjum, Momotaj Jahan, Farjana Nikkon, Mominul Hoque, Apurba Kumar Roy, Azizul Haque, Seiichiro Himeno, Khaled Hossain, Zahangir Alam Saud
Groundwater used for drinking has been contaminated with naturally occurring inorganic arsenic and other metals, and metal-contaminated drinking water is the biggest threat to public health in Bangladesh. Toxic metals present in the drinking water have a strong relationship with chronic diseases in humans. Antimony (Sb), a naturally occurring metal, has been reported to be present in the drinking water along with other heavy metals in Bangladesh. Although Sb is present in the environment, very little attention has been given to the toxic effects of Sb...
March 8, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29459354/mercury-and-metallothioneins-in-blood-fractions-and-tissues-of-captive-morelet-s-crocodiles-in-quintana-roo-mexico
#5
A M Buenfil-Rojas, T Alvarez-Legorreta, J R Cedeño-Vázquez
Even though studies of heavy metals and their relation with metallothioneins (MTs) in reptile tissues have been conducted, research on heavy metals and MTs in organs and blood fractions of crocodylians is limited. To date there are no studies on the distribution of MTs in organs and their relation with mercury (Hg), or the concentration of MTs in plasma and erythrocytes of crocodylians. In order to understand the role of MTs in crocodiles, our aim was to assess the detoxification mechanisms for exposure to metals in Morelet's crocodile (Crocodylus moreletii) by using two biomarkers (Hg and MTs) in blood fractions and tissues, and comparing them with concentrations between two populations of crocodiles, one previously wild and currently captive (Theme Park) and another raised in a Wildlife Management Unit (WMU)...
May 2018: Chemosphere
https://www.readbyqxmd.com/read/29284245/concentrations-of-selected-toxic-elements-in-ewe-living-near-an-environmentally-loaded-area-of-eastern-part-of-slovakia
#6
Terézia Pošiváková, Rudolf Hromada, Katarína Veszelits Laktičová, Mária Vargová, Ľuboš Korytár, Jozef Švajlenka, Miroslav Húska, Elena Hatalová, Ján Pošivák, Róbert Klein
INTRODUCTION AND OBJECTIVE: Research focused on the monitoring of selected heavy metals in ewes' blood. Concentrations of selected toxic elements, lead, cadmium and zinc, in ewes living near an environmentally-loaded area, concerned 15 ewes (aged 3-4 years) in good physical condition, during the spring of 2014 and 2015 in the eastern part of Slovakia. The aim of the research was to determine the concentration of selected heavy metals and state the correlations of selected heavy metals in ewes' blood...
December 23, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/29236077/a-pilot-study-of-children-s-blood-lead-levels-in-mount-isa-queensland
#7
Donna Green, Marianne Sullivan, Nathan Cooper, Annika Dean, Cielo Marquez
Mount Isa, Queensland, is one of three Australian cities with significant lead emissions due to nonferrous mining and smelting. Unlike the two other cities with lead mines or smelters, Mount Isa currently has no system of annual, systematic, community-wide blood lead level testing; and testing rates among Indigenous children are low. In previous screenings, this group of children has been shown to have higher average blood lead levels than non-Indigenous children. The first aim of this study was to assess whether parents and children would participate in less invasive, rapid point-of-care capillary testing...
December 13, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29093364/mercury-poisoning-in-a-fisherman-working-on-a-pelagic-fishing-vessel-due-to-excessive-tuna-consumption
#8
Ji-Sung Ahn, Kyung Wook Kang, Won-Yang Kang, Hyeong-Min Lim, Seunghyeon Cho, Jai-Dong Moon, Won-Ju Park
OBJECTIVE: To report the case of a fisherman who developed chronic mercury poisoning due to excessive consumption of tuna while working on a pelagic fishing vessel. CASE REPORT: A 48-year-old male deep-sea fisherman developed paresthesia and pain in both legs while working at sea. He continued working for over 4 months on a pelagic fishing vessel but was eventually unable to function normally as his condition deteriorated. Upon arrival on land, he received specialist treatment, including imaging studies, for 2 months; however, the cause of the symptoms was not identified...
January 25, 2018: Journal of Occupational Health
https://www.readbyqxmd.com/read/29078766/a-comparison-of-arsenic-exposure-in-young-children-and-home-water-arsenic-in-two-rural-west-texas-communities
#9
Michelle Del Rio, Juan Alvarez, Tania Mayorga, Salvador Dominguez, Christina Sobin
BACKGROUND: In a previously conducted Health Impact Assessment of a well-water dependent southwest community, arsenic (As) levels greater than the EPA Maximum Contaminant Level (10 μg/L) were identified in home water samples. The goals of this study were to test whether children from the previously studied well-water dependent community (Community 1) had higher blood As levels than children from a demographically similar and geographically nearby community dependent on a municipal water supply (Community 2); to test whether home water As levels predicted child As blood levels; and to examine how child As blood levels changed over time...
October 27, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29056070/the-effects-of-lead-on-gabaergic-interneurons-in-rodents
#10
Yifei Duan, Leiwen Peng, Hua Shi, Yongmei Jiang
Lead is a heavy metal that affects various systems and organs in the body, especially the nervous system. In this study, the in vivo and in vitro effects of lead on neurons were analyzed. We divided mouse pups into three groups based on the concentration of lead exposure: the control group, the low-dose group, and the high-dose group. Changes in behavior (measured by an open-field test and a tail suspension test), blood lead levels (measured by atomic absorption spectrophotometry), the number of GABAergic interneurons (measured by immunohistochemistry), gene expression (measured by qRT-PCR), and DNA methylation (measured by pyrosequencing) were determined in the three groups...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/29034097/the-association-between-cadmium-and-lead-exposure-and-blood-pressure-among-workers-of-a-smelting-industry-a-cross-sectional-study
#11
Hyun Chan An, Joo Hyun Sung, Jiho Lee, Chang Sun Sim, Sang Hoon Kim, Yangho Kim
BACKGROUND: Lead and cadmium are harmful heavy metals that are used for a variety of occupational purposes. Considering their potentially hazardous effects on health, studies on the association between exposure to these two heavy metals and health disorders have been actively conducted. This study aimed to determine the association between blood lead and cadmium levels and blood pressure in workers exposed to lead and cadmium in a smelter. METHODS: Nine hundred and sixty-three male workers who worked in a smelter, and underwent medical examinations at the Ulsan University Hospital between January 1 and December 31, 2014, were selected as participants...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29029324/cadmium-exposure-impairs-cognition-and-olfactory-memory-in-male-c57bl-6-mice
#12
Hao Wang, Liang Zhang, Glen M Abel, Daniel R Storm, Zhengui Xia
Cadmium (Cd) is a heavy metal of high interest to the superfund initiative. Recent epidemiology studies have suggested a possible association between Cd exposure and cognitive as well as olfactory impairments in humans. However, studies in animal models are needed to establish a direct causal relationship between Cd exposure and impairments in cognition and olfaction. This study aims to investigate the toxic effect of Cd on cognition and olfactory function in mice. One group of 8-week-old C57BL/6 male mice was exposed to 3 mg/l Cd (in the form of CdCl2) through drinking water for 20 weeks for behavior tests and final blood Cd concentration analysis...
January 1, 2018: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28974026/joint-toxicity-of-different-heavy-metal-mixtures-after-a-short-term-oral-repeated-administration-in-rats
#13
Hong Su, Zhou Li, Samuel Selorm Fiati Kenston, Hongbo Shi, Yafei Wang, Xin Song, Yuanliang Gu, Tabatha Barber, Joni Aldinger, Baobo Zou, Min Ding, Jinshun Zhao, Xialu Lin
The systemic toxicity of different combinations of heavy metal mixtures (HMMs) was studied according to equivalent proportions of the eight most common detectable heavy metals found in fish consumption in the Ningbo area of China. The ion mass proportions of Zn, Cu, Mn, Cr, Ni, Cd, Pb, and Hg were 1070.0, 312.6, 173.1, 82.6, 30.0, 13.3, 6.6, and 1.0, respectively. In this study, 10 experimental groups were set as follows: M8 (Pb + Cd + Hg + Ni + Cu + Zn + Mn + Cr); M5 (Pb + Cd + Hg + Ni + Cr); M4A (Pb + Cd + Hg + Ni); M4B (Cu + Zn + Mn + Cr); M3 (Cu + Zn + Mn); Cr; Cu; Zn; Mn; and control...
October 1, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28971261/studies-on-acute-and-chronic-toxicity-of-cadmium-to-freshwater-snail-lymnaea-acuminata-lamarck-with-special-reference-to-behavioral-and-hematological-changes
#14
Kishore Dhara, Nimai Chandra Saha, Arpan Kumar Maiti
Molluscs have long been regarded as promising bioindicator and biomonitoring subjects for heavy metals as molluscs are highly tolerant to heavy metals and exhibit high accumulation in their body. In spite of several previous studies about the impact of cadmium on molluscs, little information exists in literatures concerning the toxic effects of cadmium on Lymnaea acuminata, especially pertaining to behavioral and hematological changes as these are considered effective bioindicators and biomonitoring variables for detecting heavy metals in polluted water bodies...
December 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28920782/evaluation-of-lead-and-mercury-prevalence-in-bald-eagles-haliaeetus-leucocephalus-from-the-mid-atlantic-united-states
#15
Andreas Eleftheriou, Lisa Murphy, Sallie Welte
Heavy metal contamination of the environment remains a critical issue. Lead and mercury exposure, particularly, can affect avian health. Bald eagles (Haliaeetus leucocephalus) ingest these metals through their diets. Lead and mercury prevalence were examined in bald eagles from three mid-Atlantic US states between 2004 and 2013. Blood samples were analyzed using atomic absorption spectrometry. Wilcoxon score tests were used to detect differences in lead and mercury over time. Counties of origin for birds with clinically significant metal levels were identified...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28829631/in-vitro-evaluation-of-damage-by-heavy-metals-in-tight-and-gap-junctions-of-sertoli-cells
#16
Juan Ramos-Treviño, Susana Bassol-Mayagoitia, Pablo Ruiz-Flores, Perla Karina Espino-Silva, Odila Saucedo-Cárdenas, Sheila Adela Villa-Cedillo, Martha P Nava-Hernández
The Sertoli cell plays a vital role during the spermatogenesis process and has been identified as one of the main targets of the toxic action of heavy metals on the seminiferous epithelium. In the present work, the effect of lead (Pb), Arsenic (As), and Cadmium (Cd) in primary cultures of Sertoli cells was analyzed by measuring the expression of the genes Cldn11, Ocln, and Gja1 that participate in the tight and gap junctions, which are responsible for maintaining the blood-testis barrier. Sertoli cells were isolated from the testes of Wistar rats...
October 2017: DNA and Cell Biology
https://www.readbyqxmd.com/read/28827971/the-potency-of-red-seaweed-eucheuma-cottonii-extracts-as-hepatoprotector-on-lead-acetate-induced-hepatotoxicity-in-mice
#17
Giftania Wardani, Nuraini Farida, Rina Andayani, Mahmiah Kuntoro, Sri Agus Sudjarwo
BACKGROUND: Lead is one of the most toxic metals, producing severe organ damage in animals and humans. Oxidative stress is reported to play an important role in lead acetate-induced liver injury. AIM: This study was carried out to investigate the role of ethanol extract of Eucheuma cottonii in protecting against lead acetate-induced hepatotoxicity in male mice. MATERIALS AND METHODS: The sample used fifty male mice which were divided into five groups: negative control (mice were given daily with Aquadest); positive control (mice were given daily with lead acetate 20 mg/kg body weight (BW) orally once in a day for 21 days); and the treatment group (mice were given E...
July 2017: Pharmacognosy Research
https://www.readbyqxmd.com/read/28802093/clinical-aspects-of-opium-adulterated-with-lead-in-iran-a-review
#18
REVIEW
Samira Alinejad, Jan Aaseth, Mohammad Abdollahi, Hossein Hassanian-Moghaddam, Omid Mehrpour
Adulteration of drugs with poisonous substances during production or consumption has caused numerous health problems. Among contaminants that have the potential of producing poisonous effects are the heavy metals lead, arsenic and thallium that make up an important group of toxic substances. The emergence of these new health problems related to opioid abuse has precipitated this MiniReview on the status of the most hazardous and common opioid adulterants. In fact, adulterated opium is a major public health problem and can threaten the health of users...
January 2018: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28734265/decreased-lung-function-with-mediation-of-blood-parameters-linked-to-e-waste-lead-and-cadmium-exposure-in-preschool-children
#19
Xiang Zeng, Xijin Xu, H Marike Boezen, Judith M Vonk, Weidong Wu, Xia Huo
Blood lead (Pb) and cadmium (Cd) levels have been associated with lower lung function in adults and smokers, but whether this also holds for children from electronic waste (e-waste) recycling areas is still unknown. To investigate the contribution of blood heavy metals and lung function levels, and the relationship among living area, the blood parameter levels, and the lung function levels, a total of 206 preschool children from Guiyu (exposed area), and Haojiang and Xiashan (reference areas) were recruited and required to undergo blood tests and lung function tests during the study period...
November 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28667913/lead-and-cadmium-exposure-higher-thyroid-antibodies-and-thyroid-dysfunction-in-chinese-women
#20
Xiaomin Nie, Yi Chen, Yingchao Chen, Chi Chen, Bing Han, Qin Li, Chunfang Zhu, Fangzhen Xia, Hualing Zhai, Ningjian Wang, Yingli Lu
BACKGROUND: Exposure to lead(Pb) or cadmium(Cd) has been related to decreasing thyroxine in many previous studies. The underlying mechanisms have not been clarified. Heavy metal-induced thyroid autoimmunity in pregnant women has been found, despite having been rarely explored in the general population. OBJECTIVES: We aimed to determine whether the blood levels of lead(BPb) or cadmium(BCd) related to the levels of sera antibodies to thyroid proteins and thyroid dysfunction in the general population...
November 2017: Environmental Pollution
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