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https://www.readbyqxmd.com/read/29764491/does-a-low-fodmaps-diet-reduce-symptoms-of-functional-abdominal-pain-disorders-a-systematic-review-in-adult-and-paediatric-population-on-behalf-of-italian-society-of-pediatrics
#1
REVIEW
Rossella Turco, Silvia Salvatore, Erasmo Miele, Claudio Romano, Gian Luigi Marseglia, Annamaria Staiano
BACKGROUND: Despite the rising of the Functional Gastrointestinal Disorders (FGIDs)' incidence in the last years, the etio-pathogenesis of FGIDs remains unclear. The diet seems to play an important role in these disorders. Indeed, at least two thirds of adult patients with Irritable Bowel Syndrome (IBS) and of children with FGIDs perceive their GI symptoms to be food-related. In particular, in the last years, more interest has been focused in the low Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyol (FODMAPs) diet...
May 15, 2018: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29764234/the-role-of-diet-in-the-management-of-irritable-bowel-syndrome-a-focus-on-fodmaps
#2
Russell Dolan, William D Chey, Shanti Eswaran
Irritable bowel syndrome is a common condition that negatively impacts quality of life and results in significant health care expenditures. The vast majority of IBS patients associate their symptoms with eating. Numerous randomized, controlled trials suggest that restriction of dietary FODMAPs improves overall symptoms, abdominal pain, bloating and quality of life in more than half of IBS sufferers. There is emerging data which suggests that other diets (gluten free, guided elimination diets) might also be of benefit to IBS patients...
May 15, 2018: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29762380/clinical-characteristics-of-disaccharidase-deficiencies-among-children-undergoing-upper-endoscopy
#3
Stanley A Cohen, Hannah Oloyede, Benjamin D Gold, Aminu Mohammed, Heather E Elser
OBJECTIVES: The epidemiology and clinical significance of disaccharidase deficiencies have not been thoroughly characterized. Recent work suggests at least genetic sucrase-isomaltase deficiency is more prevalent than previously believed. Because lactase deficiency (LD) is well described, the present study focuses on the clinical characteristics of children with disaccharidase deficiencies determined by esophagogastroduodenoscopy. METHODS: Endoscopic records were reviewed from patients undergoing esophagogastroduodenoscopies with biopsies assayed for disaccharidase activity performed by 13 pediatric gastroenterologists during 5 years (2010-2014)...
June 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29761727/tubular-colonic-duplication-in-an-adult-case-report-and-brief-literature-review
#4
Xin Wu, Xiequn Xu, Chaoji Zheng, Binglu Li
Gastrointestinal tract duplication is a rare congenital anomaly that can occur anywhere along the alimentary tract. Most of the reported patients present with acute abdomen during childhood. We describe a case of tubular colonic duplication in an adult. The patient was a 25-year-old woman who presented with abdominal pain, bloating, nausea, and emesis for 3 days. The physical examination was remarkable for abdominal distension, tenderness, and rigidity. Abdominal computed tomography scan revealed abnormal intestinal dilatation...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29757053/applying-a-low-fodmap-dietary-intervention-to-a-female-ultra-endurance-runner-with-irritable-bowel-syndrome-during-a-multi-stage-ultra-marathon
#5
Stephanie K Gaskell, Ricardo J S Costa
Malabsorption of Fermentable Oligo- Di- and Mono-saccharides and Polyols (FODMAPs) in response to prolonged exercise may increase incidence of upper- and lower-gastrointestinal symptoms (GIS), which are known to impair exercise performance. The case-study aimed to explore the impact of a low-FODMAP diet on exercise-associated GIS in a female ultra-endurance runner diagnosed with irritable bowel syndrome (IBS), competing in a six-day 186.7 km mountainous multi-stage ultra-marathon (MSUM). IBS symptom severity score at diagnosis was 410 and following a low-FODMAP diet (3...
May 14, 2018: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29742779/efficacy-and-tolerability-of-linaclotide-in-the-treatment-of-irritable-bowel-syndrome-with-constipation-in-a-real%C3%A2-world-setting-results-from-a-german-noninterventional-study
#6
Viola Andresen, Stephan Miehlke, Elmar Beck, Gwen Wiseman, Peter Layer
BACKGROUND:  Linaclotide is a minimally absorbed peptide guanylate cyclase-C agonist approved for the treatment of irritable bowel syndrome with constipation (IBS-C). This study assessed the efficacy and tolerability of linaclotide in IBS-C in routine clinical practice in Germany. METHODS:  This was a 52-week, noninterventional study of linaclotide in patients aged ≥ 18 years with moderate to severe IBS-C. Severity of abdominal pain and bloating and frequency of bowel movements were assessed over 5 study visits...
May 9, 2018: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29738302/care-and-treatment-of-a-rare-mycobacterium-avium-complex-infected-wound-a-case-report
#7
Min Wei, Qixia Jiang, Jiandong Wang
An unusual presentation of Mycobacterium avium complex (MAC), unlikely to be encountered in an outpatient dermatology setting, was diagnosed in a patient without an immunodeficiency. A 47-year-old woman, who was immunocompetent and had no risk factors, presented with a full-thickness, infected wound (large amounts of purulent exudate and severe pain) on her back, which had been present for two months. She was diagnosed as having an MAC infection, using a DNA microarray chip method. The patient underwent wound drainage and a fresh silver-containing dressing was applied daily for two months...
May 2, 2018: Journal of Wound Care
https://www.readbyqxmd.com/read/29737803/efficacy-of-actinidin-containing-kiwifruit-extract-zyactinase-on-constipation-a-randomised-double-blinded-placebo-controlled-clinical-trial
#8
Iona Weir, Quan Shu, Nengding Wei, Chengkai Wei, Yi Zhu
BACKGROUND AND OBJECTIVES: Zyactinase® is an extract of green kiwifruit, formulated into the consumer healthcare products marketed as Phloe® and Kivia, used to assist in the relief of the symptoms associated with a range of digestive system dysfunction, including constipation and Irritable Bowel Syndrome (IBS). METHODS AND STUDY DESIGN: A randomised, double-blind, placebo-controlled clinical trial was undertaken to determine the ef-fects of the kiwifruit extract on bowel movement, stool formation and IBS associated symptoms amongst a sub-ject group of generally healthy individuals experiencing a period of moderate constipation...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29729056/a-case-of-small-intestinal-bacterial-overgrowth-performed-capsule-and-double-balloon-endoscopy
#9
Ichiro Otani, Shiro Oka, Shinji Tanaka
A 67-year old woman who had received treatment with prednisolone for systemic scleroderma visited our hospital. She complained of mild abdominal pain, bloating, anorexia, watery stools (approximately three times a day). Abdominal computed tomography showed high contrast appearance and thickening of the entire small intestinal wall as well as accumulation of intestinal fluid with no mechanical obstruction (Figure 1). Capsule endoscopy (Figure 2a) and antegrade double-balloon endoscopy (Figure 2b) revealed retention of cloudy intestinal fluid throughout the entire small intestine with reddish and edematous mucosa...
May 5, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29702295/functional-dyspepsia-and-severity-of-psychologic-symptoms-associate-with-postprandial-symptoms-in-patients-with-irritable-bowel-syndrome
#10
Daniel Pohl, Lukas Van Oudenhove, Hans Törnblom, Boris Le Nevé, Jan Tack, Magnus Simrén
BACKGROUND & AIMS: Patients with irritable bowel syndrome (IBS) have an increased response of postprandial symptoms to a combined lactulose nutrient challenge test, compared with healthy volunteers. We investigated the associations among co-morbid functional dyspepsia (FD), severity of psychologic symptoms, and breath test results in response to this test. METHODS: We performed a prospective study of 205 patients with IBS (Rome III criteria), 94 of whom also had FD (IBS-FD), and 83 healthy volunteers in Sweden from 2008 through 2015...
April 24, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29701506/outcomes-of-laparoscopic-subtotal-colectomy-with-cecorectal-anastomosis-for-slow-transit-constipation-a-single-center-retrospective-study
#11
Dong Yang, Liang He, Tong-Rong Su, Yan Chen, Quan Wang
PURPOSE: To study the safety and efficacy of laparoscopic subtotal colectomy (LASC) with cecorectal anastomosis for slow-transit constipation (STC). METHODS: This study was a retrospective review of all patients undergoing LASC with cecorectal anastomosis for STC between March 2010 and May 2017. The main variables included the operative time, blood loss, length of postoperative hospital stay, complications, and long-term outcomes. RESULTS: In this analysis, 56 patients were included...
April 27, 2018: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/29700963/reduction-in-pain-is-it-worth-the-gain-the-effect-of-opioids-on-the-gi-tract
#12
REVIEW
J Nee, V Rangan, A Lembo
The use of opioid medications for acute and chronic pain has increased significantly in the past 20 years in the United States. Given the high density of opioid receptors in the gastrointestinal tract, side effects are common in these patients including constipation, dysphagia, bloating, nausea, and vomiting. These side effects, which are experienced by most patients who take opioids, can lead to significant impairment in quality of life. Unlike other side effects from opioids, gastrointestinal side effects do not diminish with continued use, often leading patients to reduce or discontinue their opioid treatment to relieve these side effects...
May 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29698053/comparison-of-chang-run-tong-and-forlaxin-treatment-of-constipation-in-elderly-diabetic-patients
#13
Dong Zhao, Jing-Bo Zhao
OBJECTIVE: Constipation is quite common and has impact on life quality in the elderly diabetic patients; therefore it is important to seek better treatments. The aim of this study is to evaluate the effect of Chang Run Tong (CRT) decoction on constipation in elderly diabetic patients in comparison with the effect of Macrogol 4000 powder (Forlax). DESIGN: This study was designed as a prospective study consisting of two parallel arms: CRT group and Forlax group. SETTINGS/LOCATION: The study was conducted in China-Japan Hospital...
April 26, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29695183/efficacy-of-bacillus-coagulans-unique-is2-in-treatment-of-irritable-bowel-syndrome-in-children-a-double-blind-randomised-placebo-controlled-study
#14
M Ratna Sudha, N Jayanthi, M Aasin, R D Dhanashri, T Anirudh
The efficacy of the probiotic strain, Bacillus coagulans Unique IS2 in the treatment of Irritable Bowel Syndrome (IBS) was evaluated in children. A total of 141 children of either sex in the age group 4-12 years, diagnosed with IBS according to the Rome III criteria, participated in the double-blind randomised controlled trial. Children received either B. coagulans Unique IS2 chewable tablets or placebo once daily for eight weeks followed by a two week follow-up period. Reduction in pain intensity as well as other symptoms associated with Irritable Bowel Syndrome like abdominal discomfort, bloating, distension, sense of incomplete evacuation, straining at stool, urgency of bowel movement, passage of gas and mucus, and bowel habit satisfaction were assessed...
April 26, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/29692663/uncommon-reasons-of-the-digestive-tract-related-paraneoplastic-syndromes-in-children-with-neuroblastic-tumors-three-case-reports
#15
Elżbieta Czkwianianc, Beata Zalewska-Szewczyk, Józef Kobos, Anna Socha-Banasiak, Szymon Janczar, Sylwia Prymus-Kasińska, Joanna Kazanek-Zasada, Wojciech Młynarski
Aim of the study: presentation of the uncommon paraneoplastic syndromes related to the gastrointestinal tract that may occur in children with neuroblastic tumors and their impact on the disease course. Material and methods: Retrospective analysis of three cases of patients mainly with digestive tract-related symptoms, who were originally admitted to the gastroenterology department from 2013 to 2016 and were finally diagnosed with neuroblastic tumors. Results: The clinical data analysis showed that the symptoms from gastrointestinal tract were dominant in analyzed subjects...
2018: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/29691369/does-colectomy-predispose-to-small-intestinal-bacterial-sibo-and-fungal-overgrowth-sifo
#16
Satish S C Rao, George Tan, Hamza Abdulla, Siegfried Yu, Sebastian Larion, Pornchai Leelasinjaroen
OBJECTIVES: After subtotal colectomy, 40% of patients report chronic gastrointestinal symptoms and poor quality of life. Its etiology is unknown. We determined whether small intestinal bacterial overgrowth (SIBO) or small intestinal fungal overgrowth (SIFO) cause gastrointestinal symptoms after colectomy. METHODS: Consecutive patients with unexplained abdominal pain, gas, bloating and diarrhea (>1 year), and without colectomy (controls), and with colectomy were evaluated with symptom questionnaires, glucose breath test (GBT) and/or duodenal aspiration/culture...
April 25, 2018: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/29685047/long-term-results-of-linaclotide-in-the-treatment-of-constipation-type-irritable-bowel-syndrome
#17
Fernando Geijo Martínez, Ana Sánchez Garrido, Héctor Marcos Prieto, Concepción Piñeiro Pérez, Ana Beatriz Prieto Bermejo, Alberto Álvarez Delgado, Antonio Velasco Guardado, Antonio Rodríguez Pérez
BACKGROUND: constipation-predominant irritable bowel syndrome (C-IBS) is a prevalent, complex and multifactorial disorder that represents a challenge in terms of diagnosis and therapeutic management. OBJECTIVE: to evaluate the effectiveness, safety and treatment satisfaction of linaclotide in C-IBS patients. METHODS: prospective, single-center and observational study conducted in patients diagnosed with C-IBS. The patients were treated with linaclotide (Constella®, Allergan Inc...
April 24, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29678362/bowel-symptoms-in-patients-that-receive-proton-pump-inhibitors-results-of-a-multicenter-survey-in-mexico
#18
M J Schmulson, A C Frati-Munari
INTRODUCTION: Proton pump inhibitors (PPIs) have been associated with small intestinal bacterial overgrowth (SIBO), which increases with prolonged PPI use, and SIBO has been associated with irritable bowel syndrome (IBS). OBJECTIVE: The aim of the present study was to study the prevalence of bowel symptoms in patients treated with PPIs in Mexico. METHODS: Gastroenterologists in 36 cities surveyed patients treated with PPIs, utilizing an ad hoc questionnaire to determine the presence of bowel symptoms and IBS...
April 17, 2018: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/29674959/meal-sensing-signaling-pathways-in-functional-dyspepsia
#19
REVIEW
Amanda J Page, Hui Li
The upper gastrointestinal tract plays an important role in sensing the arrival, amount and chemical composition of a meal. Ingestion of a meal triggers a number of sensory signals in the gastrointestinal tract. These include the response to mechanical stimulation (e.g., gastric distension), from the presence of food in the gut, and the interaction of various dietary nutrients with specific "taste" receptors on specialized enteroendocrine cells in the small intestine culminating in the release of gut hormones...
2018: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/29673434/diphyllobothriasis-in-a-u-s-military-aviator
#20
Stephen D Kasteler
BACKGROUND: Diphyllobothriasis is estimated to afflict 10-20 million people worldwide; however, this is the first case reported in a United States military aviator. Among the largest parasites of humans, the "fish tapeworm" grows from 2-15 m in length, can live >20 yr in the intestines, and is contracted through consumption of uncooked, unfrozen freshwater or anadromous fish species. CASE REPORT: A 32-yr-old male F-22 pilot presented with mild stomach cramping, bloating, nausea, and intermittent loose stools...
May 1, 2018: Aerospace Medicine and Human Performance
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