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https://www.readbyqxmd.com/read/27905899/a-case-of-extragastrointestinal-stromal-tumor-complicated-by-severe-hypoglycemia-a-unique-presentation-of-a-rare-tumor
#1
Zeb Saeed, Solaema Taleb, Carmella Evans-Molina
BACKGROUND: Non-Islet Cell Tumor Hypoglycemia (NICTH) is a rare paraneoplastic cause of hypoglycemia arising from excess tumor production of insulin-like growth factor. The objective of this report is to describe an unusual case of Extragastrointestinal Stromal Tumor (EGIST) associated NICTH. CASE PRESENTATION: A 64 year-old African female was brought to the emergency room with a 1-month history of recurrent syncope, weight loss, and abdominal bloating. Serum blood glucose was discovered to 39 mg/dL, when insulin, proinsulin, and C-peptide were suppressed...
December 1, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27901279/dopamine-agonists-for-preventing-ovarian-hyperstimulation-syndrome
#2
REVIEW
Huilin Tang, Selma Mourad, Suo-Di Zhai, Roger J Hart
BACKGROUND: Ovarian hyperstimulation syndrome (OHSS) is a potentially serious complication of ovarian stimulation in assisted reproduction technology (ART). It is characterised by enlarged ovaries and an acute fluid shift from the intravascular space to the third space, resulting in bloating, increased risk of venous thromboembolism and decreased organ perfusion. Most cases are mild, but forms of moderate or severe OHSS appear in 3% to 8% of in vitro fertilisation (IVF) cycles. The dopamine agonist cabergoline was introduced as a secondary prevention intervention for OHSS in women at high risk of OHSS undergoing ART treatment...
November 30, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27896652/the-long-term-efficacy-and-safety-of-pyloroplasty-combined-with-gastric-electrical-stimulation-therapy-in-gastroparesis
#3
Brian R Davis, Irene Sarosiek, Mohammad Bashashati, Ben Alvarado, Richard W McCallum
INTRODUCTION: Gastroparesis is delayed gastric emptying without mechanical obstruction. Symptomatic improvement can be 50-60% with gastric electrical stimulation. To address delayed gastric emptying, pyloroplasty was added. This study examines the long-term efficacy and safety of simultaneous gastric electrical stimulator implantation and pyloroplasty. METHODS: In this prospective single-arm trial conducted from 2012 to 2015, 27 [23 females; mean age 43 (22-63)] gastroparesis patients who underwent simultaneous gastric electrical stimulator implantation with Heineke-Mikulicz pyloroplasty were studied...
November 28, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27890460/prevalence-of-small-intestinal-bacterial-overgrowth-in-multiple-sclerosis-a-case-control-study-from-china
#4
Yongbo Zhang, Guoyi Liu, Yuanli Duan, Xinwen Han, Huihua Dong, Jia Geng
OBJECTIVE: It's hypothesized that gastrointestinal microbiota might play an important role in pathogenesis of multiple sclerosis (MS). The aim of the present study was to assess the prevalence of small intestinal bacterial overgrowth (SIBO) in MS patients compared with sex and age matched controls without MS. METHODS: The present study was a case-control type, it included 118 patients with definitive MS and 118 age-sex matched controls. Progression of disability was assessed using the Multiple Sclerosis Severity Score (MSSS)...
November 16, 2016: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/27872184/functional-variants-in-the-sucrase-isomaltase-gene-associate-with-increased-risk-of-irritable-bowel-syndrome
#5
Maria Henström, Lena Diekmann, Ferdinando Bonfiglio, Fatemeh Hadizadeh, Eva-Maria Kuech, Maren von Köckritz-Blickwede, Louise B Thingholm, Tenghao Zheng, Ghazaleh Assadi, Claudia Dierks, Martin Heine, Ute Philipp, Ottmar Distl, Mary E Money, Meriem Belheouane, Femke-Anouska Heinsen, Joseph Rafter, Gerardo Nardone, Rosario Cuomo, Paolo Usai-Satta, Francesca Galeazzi, Matteo Neri, Susanna Walter, Magnus Simrén, Pontus Karling, Bodil Ohlsson, Peter T Schmidt, Greger Lindberg, Aldona Dlugosz, Lars Agreus, Anna Andreasson, Emeran Mayer, John F Baines, Lars Engstrand, Piero Portincasa, Massimo Bellini, Vincenzo Stanghellini, Giovanni Barbara, Lin Chang, Michael Camilleri, Andre Franke, Hassan Y Naim, Mauro D'Amato
OBJECTIVE: IBS is a common gut disorder of uncertain pathogenesis. Among other factors, genetics and certain foods are proposed to contribute. Congenital sucrase-isomaltase deficiency (CSID) is a rare genetic form of disaccharide malabsorption characterised by diarrhoea, abdominal pain and bloating, which are features common to IBS. We tested sucrase-isomaltase (SI) gene variants for their potential relevance in IBS. DESIGN: We sequenced SI exons in seven familial cases, and screened four CSID mutations (p...
November 21, 2016: Gut
https://www.readbyqxmd.com/read/27869786/a-role-for-leucoanthocyanidin-reductase-in-the-extension-of-proanthocyanidins
#6
Chenggang Liu, Xiaoqiang Wang, Vladimir Shulaev, Richard A Dixon
Proanthocyanidins (PAs) are the second most abundant plant polyphenolic compounds after lignin. PAs affect taste, mouth feel and astringency of many fruits, wines and beverages(1,2), have been associated with reduced risks of cardiovascular disease, cancer and Alzheimer's disease(3-5), can improve nutrition and prevent bloat in ruminant animals(6) and enhance soil nitrogen retention(7). PAs are oligomers and polymers of flavan-3-ols, primarily (-)-epicatechin and (+)-catechin, but the mechanism by which the monomers polymerize and become insoluble is currently unknown...
November 21, 2016: Nature Plants
https://www.readbyqxmd.com/read/27865497/invited-review-abomasal-emptying-in-calves-and-its-potential-influence-on-gastrointestinal-disease
#7
Johann Burgstaller, Thomas Wittek, Geof W Smith
Creating the ideal nutrition program for calves is a demanding task that has undergone tremendous change in recent years. Products and technologies including novel milk replacers and automated calf feeding systems have been developed to facilitate the ability of dairy producers to feed for higher growth rates before weaning. The creation of new feeding programs and milk replacers has to be looked at carefully, not only from a nutrition point of view but also from the perspective of a potential effect on physiologic digestion and calf health...
November 16, 2016: Journal of Dairy Science
https://www.readbyqxmd.com/read/27845950/carbon-dioxide-insufflation-during-colonoscopy-in-inflammatory-bowel-disease-patients-a-double-blind-randomized-single-center-trial
#8
Přemysl Falt, Vít Šmajstrla, Petr Fojtík, Martin Hill, Ondřej Urban
OBJECTIVE: Bowel distension by insufflated air causes abdominal discomfort after colonoscopy. Carbon dioxide (CO2) instead of air insufflation during colonoscopy can reduce postprocedural discomfort in diagnostic and screening cases. Discomfort after colonoscopy and CO2 insufflation have never been studied in inflammatory bowel disease (IBD) patients, characterized by younger age, structural changes of the colon, and need for repeated and frequently uncomfortable colonoscopies. Our trial was designed to evaluate postprocedural discomfort associated with CO2 compared with air insufflation in unsedated or minimally sedated patients with known IBD...
November 11, 2016: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27845337/multi-center-double-blind-randomized-placebo-controlled-parallel-group-study-to-evaluate-the-benefit-of-the-probiotic-bifidobacterium-infantis-35624-in-non-patients-with-symptoms-of-abdominal-discomfort-and-bloating
#9
Tamar Ringel-Kulka, Johnson McRorie, Yehuda Ringel
OBJECTIVES: Bifidobacterium infantis 35624 is a probiotic that is used often in patients with irritable bowel syndrome (IBS). Non-patients with bowel symptoms may differ from patients with IBS in the impact of their bowel symptoms on illness severity, healthcare and treatment seeking behavior. The aim of this study is to assess the efficacy of B. infantis 35624 (10(9) c.f.u. per day) for the relief of abdominal discomfort and bloating in a non-patient population. METHODS: A double-blind, randomized, placebo-controlled, parallel study with a 2-week placebo run-in phase followed by a 4-week intervention phase was conducted at ten clinical centers (USA)...
November 15, 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27837054/the-safety-and-efficacy-of-irreversible-electroporation-for-large-hepatocellular-carcinoma
#10
Jianying Zeng, Guifeng Liu, Zhong-Hai Li, Yi Yang, Gang Fang, Rong-Rong Li, Ke-Cheng Xu, Lizhi Niu
This study aimed to investigate the safety and effectiveness of irreversible electroporation ablation for unresectable large liver cancer. Fourteen patients were enrolled: 8 with large hepatocellular carcinoma (tumor diameter: 5.1-11.5 cm) and 6 with medium hepatocellular carcinoma (tumor diameter: 3.0-4.1 cm). All patients received percutaneous irreversible electroporation ablation. Ablation time and the incidence of complications were assessed by a t test. Post-irreversible electroporation and regular contrast-enhanced computerized tomography scans were performed to investigate the effect of tumor size (large vs medium) on irreversible electroporation treatment efficacy; 4-table data were assessed using a Fisher exact test...
November 11, 2016: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/27834802/prevalence-and-characterization-of-self-reported-gluten-sensitivity-in-the-netherlands
#11
Tom van Gils, Petula Nijeboer, Catharina E IJssennagger, David S Sanders, Chris J J Mulder, Gerd Bouma
BACKGROUND: A growing number of individuals reports symptoms related to the ingestion of gluten-containing food in the absence of celiac disease. Yet the actual prevalence is not well established. METHODS: Between April 2015 and March 2016, unselected adults visiting marketplaces, dental practices and a university in The Netherlands were asked to complete a modified validated questionnaire for self-reported gluten sensitivity (srGS). RESULTS: Among the 785 adults enquired, two had celiac disease...
November 8, 2016: Nutrients
https://www.readbyqxmd.com/read/27834011/post-nissen-dysphagia-and-bloating-syndrome-outcomes-after-conversion-to-toupet-fundoplication
#12
Katrin Schwameis, Jörg Zehetner, Kais Rona, Peter Crookes, Nikolai Bildzukewicz, Daniel S Oh, Geoffrey Ro, Katherine Ross, Kulmeet Sandhu, Namir Katkhouda, Jeffrey A Hagen, John C Lipham
INTRODUCTION: Protracted dysphagia and bloating are potential troublesome side effects following Nissen fundoplication. The aim of this study was to evaluate the effects of conversion from Nissen to Toupet on dysphagia and bloating. METHODS: The study used a retrospective chart review of all patients who had undergone conversion from Nissen to Toupet between 2001 and 2014. Endpoints were to determine the effect of conversion on dysphagia, bloating, and reflux control...
November 10, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27815079/efficacy-and-safety-of-enteric-coated-capsules-of-anise-oil-to-treat-irritable-bowel-syndrome
#13
Maryam Mosaffa-Jahromi, Kamran Bagheri Lankarani, Mehdi Pasalar, Suleiman Afsharypuor, Ali-Mohammad Tamaddon
ETHNOPHARMACOLOGICAL RELEVANCE: Anise is a well-recognized plant in Traditional Persian Medicine (TPM) sources. Anise oil has been suggested for the treatment of bowel disorders in Persian medical textbooks. Based on TPM scholars, this ingredient has a favorable effect on gastrointestinal diseases. We did this trial to determine the efficacy and safety of enteric coated capsules of anise oil for clinical symptoms of irritable bowel syndrome (IBS). METHODS AND MATERIALS: This three-armed double-blind clinical trial was carried out from August 2014 to February 2015...
November 1, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27812517/a-study-on-the-dietary-intake-and-the-nutritional-status-among-the-pancreatic-cancer-surgical-patients
#14
Jimin Kang, Joon Seong Park, Dong Sup Yoon, Woo Jeong Kim, Hae-Yun Chung, Song Mi Lee, Namsoo Chang
The adequate dietary intake is important to maintain the nutritional status of the patients after pancreatic cancer surgery. This prospective study was designed to investigate the dietary intake and the nutritional status of the patients who had pancreatic cancer surgery. Thirty-one patients (15 men, 16 women) were enrolled and measured body weight, body mass index (BMI), nutritional risk index (NRI), and Malnutrition Universal Screening Tool (MUST). Actual oral intake with nutritional impact symptoms recorded on the clinical research foam at every meal and medical information were collected from electronic medical charts...
October 2016: Clinical Nutrition Research
https://www.readbyqxmd.com/read/27811806/nippoparasitus-unoashicola-a-new-genus-and-species-of-philoblennid-copepod-cyclopoida-parasitic-on-the-pacific-sugar-limpet-patelloida-saccharina-linnaeus-1758-patellogastropoda-lottiidae-from-the-intertidal-zone-of-eastern-japan
#15
Daisuke Uyeno, Rie Ogasaka, Kazuya Nagasawa
Nippoparasitus unoashicola, a new genus and species of mesoparasitic copepod, is described based on specimens of both sexes collected from the mantle cavity of the Pacific sugar limpet, Patelloida saccharina (Linnaeus, 1758) (Patellogastropoda: Lottiidae), in the intertidal zone of the Uraga Channel (North Pacific Ocean), Japan. Nippoparasitus gen. nov. differs from other philoblennid genera by two unique characters: the labium is bloated and branched into multiple digitate lobes in female, and the antenna has three claw-like spines on the terminal segment...
October 11, 2016: Zootaxa
https://www.readbyqxmd.com/read/27810257/-clinical-practice-guidelines-irritable-bowel-syndrome-with-constipation-and-functional-constipation-in-adults-concept-diagnosis-and-healthcare-continuity-part-1-of-2
#16
F Mearin, C Ciriza, M Mínguez, E Rey, J J Mascort, E Peña, P Cañones, J Júdez
In this Clinical practice guide, an analysis is made of the diagnosis and treatment of adult patients with constipation and abdominal discomfort, under the spectrum of irritable bowel syndrome and functional constipation. These have an important personal, health and social impact, affecting the quality of life of these patients. In irritable bowel syndrome with a predominance of constipation, this is the predominant change in bowel movements, with recurrent abdominal pain, bloating and frequent abdominal distension...
October 31, 2016: Semergen
https://www.readbyqxmd.com/read/27807587/two-cases-of-intraluminal-windsock-diverticula-resulting-in-partial-duodenal-obstruction
#17
Vikram Anand, Justin Provost, Maged Bakr, Christopher Bach, Prakriti Merchant, Christopher Brown, Claudia Gruss
An intraluminal duodenal diverticulum (IDD) is a rare congenital anomaly that is the result of incomplete recanalization of the embryologic foregut leaving a fenestrated membrane within the lumen of the duodenum. Years of peristalsis acting on the membrane result in the formation of a diverticulum. Most patients are asymptomatic, while some may have abdominal pain, bloating, or fullness. Rare complications include gastrointestinal bleeding, obstruction, pancreatitis, and cholangitis. We present 2 cases with endoscopic findings consistent with partially obstructing symptomatic IDD...
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27799885/symptomatic-improvement-with-gluten-restriction-in-irritable-bowel-syndrome-a-prospective-randomized-double-blinded-placebo-controlled-trial
#18
Vinay G Zanwar, Sunil V Pawar, Pravir A Gambhire, Samit S Jain, Ravindra G Surude, Vinaya B Shah, Qais Q Contractor, Pravin M Rathi
BACKGROUND/AIMS: The existence of non-celiac gluten sensitivity has been debated. Indeed, the intestinal and extra-intestinal symptoms of many patients with irritable bowel syndrome (IBS) but without celiac disease or wheat allergy have been shown to improve on a gluten-free diet. Therefore, this study set out to evaluate the effects of gluten on IBS symptoms. METHODS: We performed a double-blind randomized placebo-controlled rechallenge trial in a tertiary care hospital with IBS patients who fulfilled the Rome III criteria...
October 2016: Intestinal Research
https://www.readbyqxmd.com/read/27782892/efficacy-of-synbiotic-probiotic-and-prebiotic-treatments-for-irritable-bowel-syndrome-in-children-a-randomized-controlled-trial
#19
Ahmet Baştürk, Reha Artan, Aygen Yılmaz
BACKGROUND/AIMS: Irritable bowel syndrome (IBS) is an important health problem that presents serious social burdens and high costs. Our study investigated the efficacy of synbiotic (Bifidobacterium lactis B94 with inulin), probiotic (B. lactis B94), and prebiotic (inulin) treatment for IBS in a pediatric age group. MATERIAL AND METHODS: This study was randomized, double-blind, controlled, and prospective in design and included 71 children between the ages of 4 and 16 years who were diagnosed with IBS according to the Rome III criteria...
September 2016: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/27781342/early-satiety-and-postprandial-fullness-in-gastroparesis-correlate-with-gastroparesis-severity-gastric-emptying-and-water-load-testing
#20
H P Parkman, E K Hallinan, W L Hasler, G Farrugia, K L Koch, L Nguyen, W J Snape, T L Abell, R W McCallum, I Sarosiek, P J Pasricha, J Clarke, L Miriel, J Tonascia, F Hamilton
BACKGROUND: Early satiety (ES) and postprandial fullness (PPF) are often present in gastroparesis, but the importance of these symptoms in gastroparesis has not been well-described. The aims were: (i) Characterize ES and PPF in patients with gastroparesis. (ii) Assess relationships of ES and PPF with etiology of gastroparesis, quality of life, body weight, gastric emptying, and water load testing. METHODS: Gastroparetic patients filled out questionnaires assessing symptoms (PAGI-SYM) and quality of life (PAGI-QOL, SF-36v2)...
October 25, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
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