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https://www.readbyqxmd.com/read/29444926/high-sensitivity-cardiac-troponin-i-and-the-diagnosis-of-coronary-artery-disease-in-patients-with-suspected-angina-pectoris
#1
Philip D Adamson, Amanda Hunter, Debbie M Madsen, Anoop S V Shah, David A McAllister, Tania A Pawade, Michelle C Williams, Colin Berry, Nicholas A Boon, Marcus Flather, John Forbes, Scott McLean, Giles Roditi, Adam D Timmis, Edwin J R van Beek, Marc R Dweck, Hans Mickley, Nicholas L Mills, David E Newby
BACKGROUND: We determined whether high-sensitivity cardiac troponin I can improve the estimation of the pretest probability for obstructive coronary artery disease (CAD) in patients with suspected stable angina. METHODS AND RESULTS: In a prespecified substudy of the SCOT-HEART trial (Scottish Computed Tomography of the Heart), plasma cardiac troponin was measured using a high-sensitivity single-molecule counting assay in 943 adults with suspected stable angina who had undergone coronary computed tomographic angiography...
February 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29441731/environmental-microbiology-reports-is-10
#2
EDITORIAL
Kenneth Timmis, Joan Timmis
No abstract text is available yet for this article.
February 2018: Environmental Microbiology Reports
https://www.readbyqxmd.com/read/29435773/livestock-disease-management-for-trading-across-different-regulatory-regimes
#3
Andrew M Bate, Glyn Jones, Adam Kleczkowski, Rebecca Naylor, Jon Timmis, Piran C L White, Julia Touza
The maintenance of livestock health depends on the combined actions of many different actors, both within and across different regulatory frameworks. Prior work recognised that private risk management choices have the ability to reduce the spread of infection to trading partners. We evaluate the efficiency of farmers' alternative biosecurity choices in terms of their own-benefits from unilateral strategies and quantify the impact they may have in filtering the disease externality of trade. We use bovine viral diarrhoea (BVD) in England and Scotland as a case study, since this provides an example of a situation where contrasting strategies for BVD management occur between selling and purchasing farms...
February 12, 2018: EcoHealth
https://www.readbyqxmd.com/read/29401320/abdominal-submuscular-implant-of-subcutaneous-implantable-cardioverter-defibrillator-in-a-young-child
#4
Sit-Yee Kwok, Nicholson Yam, Kin-Shing Lun, Robin Hs Chen, Timmy Wk Au, Tak-Cheung Yung
No abstract text is available yet for this article.
February 1, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29324539/trial-of-optimal-personalised-care-after-treatment-gynaecological-cancer-topcat-g-a-randomized-feasibility-trial
#5
Val Morrison, Llinos H Spencer, Nikki Totton, Kirstie Pye, Seow Tien Yeo, Caryl Butterworth, Liz Hall, Rhiannon Whitaker, Rhiannon Tudor Edwards, Laura J Timmis, Zoe Hoare, Richard D Neal, Clare Wilkinson, Simon Leeson
OBJECTIVE: This study aimed to evaluate the feasibility of completing a parallel-group randomized controlled trial to compare usual follow-up care for women who have completed treatment of gynecological cancer against a nurse-led telephone intervention, known as Optimal Personalised Care After Treatment-Gynaecological. METHODS: The unblinded trial aimed to recruit patients who had completed treatment of cervical, endometrial, epithelial ovarian, or vulval cancer within the previous 3 months at 3 North Wales hospitals...
January 10, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29283177/comparison-of-postoperative-ultrasound-criteria-to-predict-unassisted-use-of-arteriovenous-fistulas-for-hemodialysis
#6
Timmy Lee, Missy Magill, Steven K Burke, Andrew T Blair, Michelle L Robbin, Michael Allon
INTRODUCTION: Arteriovenous fistulas (AVF) frequently fail to mature. Postoperative ultrasounds provide objective measurements to predict unassisted AVF use for hemodialysis (unassisted use) and guide interventions to salvage nonmaturing AVFs. The optimal ultrasound criteria to assess AVF maturation are uncertain. We analyzed data from a multicenter, randomized, controlled, clinical trial to compare 2 published ultrasound maturation criteria used to predict unassisted AVF use for hemodialysis...
December 14, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/29280347/microbiome-yarns-human-biome-reproduction-evolution-and-visual-acuity
#7
EDITORIAL
Kenneth Timmis, Franziska Jebok, Gabriella Molinari, Manfred Rohde, Leo Lahti
No abstract text is available yet for this article.
January 2018: Microbial Biotechnology
https://www.readbyqxmd.com/read/29203125/vascular-access-outcomes-reported-in-maintenance-hemodialysis-trials-a-systematic-review
#8
Andrea K Viecelli, Emma O'Lone, Benedicte Sautenet, Jonathan C Craig, Allison Tong, Eric Chemla, Lai-Seong Hooi, Timmy Lee, Charmaine Lok, Kevan R Polkinghorne, Robert R Quinn, Tushar Vachharajani, Raymond Vanholder, Li Zuo, Ashley B Irish, Trevor A Mori, Elaine M Pascoe, David W Johnson, Carmel M Hawley
BACKGROUND: Many randomized controlled trials have been performed with the goal of improving outcomes related to hemodialysis vascular access. If the reported outcomes are relevant and measured consistently to allow comparison of interventions across trials, such trials can inform decision making. This study aimed to assess the scope and consistency of vascular access outcomes reported in contemporary hemodialysis trials. STUDY DESIGN: Systematic review. SETTING & POPULATION: Adults requiring maintenance hemodialysis...
December 1, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29190377/european-society-of-cardiology-cardiovascular-disease-statistics-2017
#9
Adam Timmis, Nick Townsend, Chris Gale, Rick Grobbee, Nikos Maniadakis, Marcus Flather, Elizabeth Wilkins, Lucy Wright, Rimke Vos, Jeroen Bax, Maxim Blum, Fausto Pinto, Panos Vardas
Aims: The European Society of Cardiology (ESC) Atlas has been compiled by the European Heart Agency to document cardiovascular disease (CVD) statistics of the 56 ESC member countries. A major aim of this 2017 data presentation has been to compare high-income and middle-income ESC member countries to identify inequalities in disease burden, outcomes, and service provision. Methods and results: The Atlas utilizes a variety of data sources, including the World Health Organization, the Institute for Health Metrics and Evaluation, and the World Bank to document risk factors, prevalence, and mortality of cardiovascular disease and national economic indicators...
November 27, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29187096/survey-of-living-organ-donors-experience-and-directions-for-process-improvement
#10
Timmy Li, M Katherine Dokus, Kristin N Kelly, Nene Ugoeke, James R Rogers, George Asham, Venkatesh Abhishek Sharma, Dominic J Cirillo, Mary K Robinson, Erika K Venniro, Jeremy G Taylor, Mark S Orloff, Scott McIntosh, Randeep Kashyap
INTRODUCTION: Understanding living organ donors' experience with donation and challenges faced during the process is necessary to guide the development of effective strategies to maximize donor benefit and increase the number of living donors. METHODS: An anonymous self-administered survey, specifically designed for this population based on key informant interviews, was mailed to 426 individuals who donated a kidney or liver at our institution. Quantitative and qualitative methods including open and axial coding were used to analyze donor responses...
September 2017: Progress in Transplantation
https://www.readbyqxmd.com/read/29177406/cardiovascular-disease-statistics-from-the-european-atlas-inequalities-between-high-and-middle-income-member-countries-of-the-esc
#11
A Timmis, C P Gale, M Flather, N Maniadakis, P Vardas
No abstract text is available yet for this article.
November 21, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29177073/the-anticipatory-stress-response-to-sport-competition-a-systematic-review-with-meta-analysis-of-cortisol-reactivity
#12
Kjell N van Paridon, Matthew A Timmis, Charlotte M Nevison, Matt Bristow
Objective: Athletes anticipating sport competition regularly experience distinct emotional and physiological responses as a result of the expected psychosocial and physical stress. Specifically, cortisol, an indicator of hypothalamic-pituitary-adrenal axis activation, prepares the athlete for the psychological and physiological demands of competition. The objective of this meta-analysis is to analyse the magnitude of the anticipatory cortisol response in athletes preparing to participate in sport competition and to examine the influence of gender, level of competition and data collection time...
2017: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29155472/experimental-reconstruction-of-double-strand-break-repair-mediated-plastid-dna-insertion-into-the-tobacco-nucleus
#13
Dong Wang, Jinbao Gu, Rakesh David, Zhen Wang, Songtao Yang, Iain R Searle, Jian-Kang Zhu, Jeremy N Timmis
The mitochondria and plastids of eukaryotic cells evolved from endosymbiotic prokaryotes. DNA from the endosymbionts has bombarded nuclei since the ancestral prokaryotes were engulfed by a precursor of the nucleated eukaryotic host. An experimental confirmation regarding the molecular mechanisms responsible for organelle DNA incorporation into nuclei has not been performed until the present analysis. Here we introduced double-strand DNA breaks into the nuclear genome of tobacco through inducible expression of I-SceI, and showed experimentally that tobacco chloroplast DNAs insert into nuclear genomes through double-strand DNA break repair...
November 20, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/29132073/evaluation-of-a-text-message-based-maintenance-intervention-for-major-depressive-disorder-after-inpatient-cognitive-behavioral-therapy
#14
Sandra Schlicker, David D Ebert, Thomas Middendorf, Ingrid Titzler, Matthias Berking
INTRODUCTION: High relapse rates in Major Depressive Disorder (MDD) indicate the need for interventions enhancing the sustainability of treatment outcomes. Primary aim of the present study was to evaluate the effectiveness of a text-message-based maintenance intervention for depression (TMMI-D). Additionally, we aimed to clarify whether the use of individualized messages would lead to better outcome than the use of standardized messages which focused upon adaptive ways of regulating undesired emotions...
October 29, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29063739/microbial-biotechnology-is-10
#15
EDITORIAL
Kenneth Timmis, Joan Timmis
No abstract text is available yet for this article.
November 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/29045628/troponin-measurement-in-patients-with-suspected-acute-coronary-syndromes-walking-beyond-the-wall
#16
Paul Collinson, Adam Timmis
No abstract text is available yet for this article.
September 22, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29045585/multimorbidity-in-heart-failure-patients
#17
Simon Woldman, Adam Timmis
No abstract text is available yet for this article.
September 25, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29043965/japanese-encephalitis-virus-transmitted-via-blood-transfusion-hong-kong-china
#18
Vincent C C Cheng, Siddharth Sridhar, Shuk-Ching Wong, Sally C Y Wong, Jasper F W Chan, Cyril C Y Yip, Chi-Hung Chau, Timmy W K Au, Yu-Yan Hwang, Carol S W Yau, Janice Y C Lo, Cheuk-Kwong Lee, Kwok-Yung Yuen
Japanese encephalitis virus (JEV) is a mosquitoborne virus endemic to China and Southeast Asia that causes severe encephalitis in <1% of infected persons. Transmission of JEV via blood transfusion has not been reported. We report transmission of JEV via blood donation products from an asymptomatic viremic donor to 2 immunocompromised recipients. One recipient on high-dose immunosuppressive drugs received JEV-positive packed red blood cells after a double lung transplant; severe encephalitis and a poor clinical outcome resulted...
January 15, 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28973321/visual-search-behavior-in-individuals-with-retinitis-pigmentosa-during-level-walking-and-obstacle-crossing
#19
Matthew A Timmis, Jon Allsop, Mohammad Baranian, James Baker, Itay Basevitch, Keziah Latham, Shahina Pardhan, Kjell N van Paridon
Purpose: Investigate the visual search strategy of individuals with retinitis pigmentosa (RP) when negotiating a floor-based obstacle compared with level walking, and compared with those with normal vision. Methods: Wearing a mobile eye tracker, individuals with RP and normal vision walked along a level walkway or walked along the walkway negotiating a floor-based obstacle. In the level walking condition, tape was placed on the floor to act as an object attracting visual attention...
September 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28967232/microbiome-yarns-microbiome-basis-of-memory
#20
EDITORIAL
Kenneth Timmis, Franziska Jebok, Gabriella Molinari, Manfred Rohde, James Kenneth Timmis
No abstract text is available yet for this article.
November 2017: Microbial Biotechnology
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