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vitamine A Neonates

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https://www.readbyqxmd.com/read/29024998/response-to-serious-danger-signals-response-to-the-effect-of-neonatal-vitamin-a-supplementation-on-morbidity-and-mortality-at-12%C3%A2-months-a-randomized-trial
#1
Emily R Smith, Alfa Muhihi, Salum Mshamu, Christopher R Sudfeld, Ramadhani Abdallah Noor, Donna Spiegelman, Roger L Shapiro, Honorati Masanja, Wafaie Fawzi
No abstract text is available yet for this article.
September 7, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29024950/serious-danger-signals-response-to-the-effect-of-neonatal-vitamin-a-supplementation-on-morbidity-and-mortality-at-12-months-a-randomized-trial
#2
Christine Stabell Benn, Ane Baerent Fisker, Peter Aaby
No abstract text is available yet for this article.
September 7, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28992261/randomized-trial-of-2-versus-1-dose-of-measles-vaccine-effect-on-hospital-admission-of-children-after-9-months-of-age
#3
Marie Brønd, Cesario L Martins, Stine Byberg, Christine S Benn, Hilton Whittle, May-Lill Garly, Peter Aaby, Ane B Fisker
Background: Two doses of measles vaccine (MV) might reduce the nonmeasles mortality rate more than 1 dose of MV does. The effect of 2 versus 1 dose on morbidity has not been examined. Within a randomized trial of the effect of 2 doses versus 1 dose of MV on mortality in Guinea-Bissau, we investigated the effect on hospital admissions. Methods: Children were randomly assigned 1:2 to receive MV at 4.5 and 9 months of age or the currently recommended dose at 9 months...
June 15, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28954525/clinical-relevance-of-gastrointestinal-microbiota-during-pregnancy-a-primer-for-nurses
#4
Seon-Yoon Chung, Jacques Ravel, Mary Regan
Emerging evidence about the human microbiome, a collective term for all the microorganisms living in and on the human body, consistently demonstrates the critical influence it has on host physiology and disease risk. The microbiota in the gastrointestinal (GI) tract has the most significant and far-reaching effect on human physiology. The maternal GI microbiota can decrease the risk of adverse pregnancy outcomes by modulating energy extraction, glucose metabolism, vitamin production, and host immunity essential for optimal maternal and neonatal health...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28954405/vitamin-d-concentration-in-maternal-and-umbilical-cord-blood-by-season
#5
Regina Wierzejska, Mirosław Jarosz, Włodzimierz Sawicki, Michał Bachanek, Magdalena Siuba-Strzelińska
Summer is generally considered to be the season when the body is well-supplied with vitamin D. The aim of this study was to compare maternal and umbilical cord blood concentrations of vitamin D during two extreme seasons of the year in Poland-winter and summer. A total of 100 pregnant women with no history of chronic diseases before pregnancy were included in the study. Pre-delivery maternal venous blood and neonatal cord blood samples were collected and total 25(OH)D concentration was measured. Data on vitamin D consumption (collected with the use of Food Frequency Questionnaire) and lifestyle factors were taken...
September 26, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28952674/consent-for-routine-neonatal-procedures-a-study-of-practices-in-irish-neonatal-units-how-do-we-compare-with-the-gold-standard-bapm-guidelines
#6
M A Ryan, C A Ryan, E Dempsey, R O'Connell
The Irish National Consent Policy (NCP) proposes that the legal requirement for consent extends to all forms of interventions, investigations and treatment, carried out on or behalf of the Health Service Executive (HSE). This study employs a quantitative descriptive approach to investigate the practices for obtaining consent for an identified group of routine neonatal procedures in neonatal facilities throughout Ireland. The BAPM (British Association of Perinatal Medicine) guidelines were identified as 'gold standard' for the purposes of this study...
June 9, 2017: Irish Medical Journal
https://www.readbyqxmd.com/read/28949421/calcium-supplementation-commencing-before-or-early-in-pregnancy-or-food-fortification-with-calcium-for-preventing-hypertensive-disorders-of-pregnancy
#7
REVIEW
G Justus Hofmeyr, Sarah Manyame
BACKGROUND: Pre-eclampsia is considerably more prevalent in low- than high-income countries. One possible explanation for this discrepancy is dietary differences, particularly calcium deficiency. Calcium supplementation in the second half of pregnancy reduces the serious consequences of pre-eclampsia and is recommended by the World Health Organization (WHO) for women with low dietary calcium intake, but has limited effect on the overall risk of pre-eclampsia. It is important to establish whether calcium supplementation before and in early pregnancy has added benefit...
September 26, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28938476/fetal-and-maternal-genetic-variants-influencing-neonatal-vitamin-d-status
#8
Ketil Størdal, Karl Mårild, German Tapia, Margareta Haugen, Arieh S Cohen, Benedicte A Lie, Lars C Stene
Objective: Several genetic polymorphisms determine vitamin D status. We aimed to estimate the strength of association of established 25-hydroyxvitamin D (25OHD) associated variants in the mother and in the fetus, with 25OHD concentration in newborn umbilical cord plasma. Methods: We randomly selected 578 mother and child dyads from the prospective Norwegian Mother and Child Cohort study (MoBa). 25OHD was assayed in maternal samples taken shortly after delivery and in cord samples...
August 18, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28938431/association-of-thyroid-function-with-maternal-and-neonatal-homocysteine-concentrations
#9
Mirjana Barjaktarovic, Eric A P Steegers, Vincent W V Jaddoe, Yolanda B de Rijke, Theo J Visser, Tim I M Korevaar, Robin P Peeters
Context: High homocysteine concentrations are associated with maternal pregnancy complications and low birth weight, jaundice and cerebrovascular accidents in neonates. Thyroid hormone may interfere with homocysteine metabolism via stimulation of vitamin B12- and folate-dependent processes and via effects on enzymes of the re-methylation pathway. Objective: Investigating the associations of maternal and neonatal thyroid function with homocysteine during pregnancy and after delivery, respectively...
September 5, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28924187/the-ipsych2012-case-cohort-sample-new-directions-for-unravelling-genetic-and-environmental-architectures-of-severe-mental-disorders
#10
C B Pedersen, J Bybjerg-Grauholm, M G Pedersen, J Grove, E Agerbo, M Bækvad-Hansen, J B Poulsen, C S Hansen, J J McGrath, T D Als, J I Goldstein, B M Neale, M J Daly, D M Hougaard, O Mors, M Nordentoft, A D Børglum, T Werge, P B Mortensen
The Integrative Psychiatric Research (iPSYCH) consortium has established a large Danish population-based Case-Cohort sample (iPSYCH2012) aimed at unravelling the genetic and environmental architecture of severe mental disorders. The iPSYCH2012 sample is nested within the entire Danish population born between 1981 and 2005, including 1 472 762 persons. This paper introduces the iPSYCH2012 sample and outlines key future research directions. Cases were identified as persons with schizophrenia (N=3540), autism (N=16 146), attention-deficit/hyperactivity disorder (N=18 726) and affective disorder (N=26 380), of which 1928 had bipolar affective disorder...
September 19, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28924002/variations-in-infant-and-childhood-vitamin-d-supplementation-programs-across-europe-and-factors-influencing-adherence
#11
Suma Uday, Ardita Kongjonaj, Magda Aguiar, Ted Tulchinsky, Wolfgang Hoegler
BACKGROUND: Nutritional rickets is a growing global public health concern despite existing prevention programs and health policies. We aimed to compare infant and childhood vitamin D supplementation policies, implementation strategies and practices across Europe and explore factors influencing adherence. METHODS: European Society for Paediatric Endocrinology Bone and Growth Plate Working Group members and other specialists completed a questionnaire on country-specific vitamin D supplementation policy and child healthcare programs, socioeconomic factors, policy implementation strategies, and adherence...
September 18, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28901944/vitamin-d-deficiency-in-pregnant-women-and-their-infants
#12
Abdurrahman Avar Özdemir, Yasemin Ercan Gündemir, Mustafa Küçük, Deniz Yıldıran Sarıca, Yusuf Elgörmüş, Yakup Çağ, Günal Bilek
OBJECTIVE: Vitamin D deficiency is a serious health problem although the improvement in socio-economic status in Turkey. The aim of this study was to evaluate the maternal vitamin D status and their effect on neonatal vitamin D status after support program for pregnant women and to detect risk factors for vitamin D deficiency in Bağcılar region in İstanbul. METHODS: A total of 97 pregnant women and 90 infants were included in this study between January and October 2016...
September 13, 2017: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/28893306/monitored-supplementation-of-vitamin-d-in-preterm-infants-mosvid-trial-study-protocol-for-a-randomised-controlled-trial
#13
Alicja Kołodziejczyk, Maria K Borszewska-Kornacka, Joanna Seliga-Siwecka
BACKGROUND: The pivotal role of vitamin D (vit D) in skeletal health is well known. Neonatal vit D storage at birth is dependent on maternal levels, and newborns receive 50-70% of their mother's 25-hydroxyvitamin D [25(OH)D]. Deficiency of vit D can lead to prematurity bone disease, with an incidence of up to 55% in infants weighing < 1000 g. The aim of this study is to assess the effectiveness of monitored supplementation of vit D in a population of preterm infants. METHODS/DESIGN: Preterm infants born at 24-32 weeks of gestation will be recruited within the first 7 days of life...
September 11, 2017: Trials
https://www.readbyqxmd.com/read/28892658/homozygous-antithrombin-deficiency-type-ii-causing-neonatal-thrombosis
#14
Vanessa Swoboda, Katharina Zervan, Katharina Thom, Christine Mannhalter, Peter Quehenberger, Ingrid Pabinger, Christoph Male
We report four children from different families with homozygous antithrombin (AT) deficiency type II affecting the heparin binding site (p.Leu131Phe mutation). All children had severe spontaneous venous and/or arterial thromboembolic events shortly after birth. This report intends to raise awareness among clinicians about this rare but severe condition. When thrombosis occurs in an otherwise healthy newborn, a severe congenital thrombophilic disorder should be considered. In homozygous AT deficiency type II, AT activity is typically reduced but may also be in the normal range, posing a diagnostic challenge...
September 4, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/28870723/managing-malnourishment-in-pregnancy-after-bariatric-surgery
#15
Rachel K Harrison, Charles Berkelhammer, Victor Suarez, Helen H Kay
BACKGROUND: Little information exists to guide monitoring and treatment of malnourishment during pregnancy after bariatric surgery. Here we present a case with severe deficiencies and recommendations for testing and treatment. CASE: Our patient underwent a duodenal switch procedure resulting in significant weight loss and numerous deficiencies. She then experienced a neonatal demise with multiple congenital abnormalities, including diaphragmatic hernia, possibly related to severe vitamin A deficiency...
September 1, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28868294/integration-of-proteomics-and-metabolomics-in-exploring-genetic-and-rare-metabolic-diseases
#16
REVIEW
Michele Costanzo, Miriam Zacchia, Giuliana Bruno, Daniela Crisci, Marianna Caterino, Margherita Ruoppolo
BACKGROUND: Inherited metabolic disorders or inborn errors of metabolism are caused by deficiency of enzymatic activities in the catabolism of amino acids, carbohydrates, or lipids. These disorders include aminoacidopathies, urea cycle defects, organic acidemias, defects of oxidation of fatty acids, and lysosomal storage diseases. Inborn errors of metabolism constitute a significant proportion of genetic diseases, particularly in children; however, they are individually rare. Clinical phenotypes are very variable, some of them remain asymptomatic, others manifest metabolic decompensation in neonatal age, and others encompass mental retardation at later age...
July 2017: Kidney Diseases
https://www.readbyqxmd.com/read/28851385/factors-associated-with-dietary-supplement-use-in-saudi-pregnant-women
#17
Hanan A Alfawaz, Nasiruddin Khan, Najlaa AlOteabi, Syed D Hussain, Nasser M Al-Daghri
BACKGROUND: The aim was to investigate the prevalence of dietary supplement use among pregnant Saudi women and its associations between various demographics. METHODS: In this cross-sectional study, a total of 137 pregnant women attending prenatal care from King Salman Hospital completed a self-administered questionnaire including socio-demographic characteristics, general awareness, attitude and behavior towards use of dietary supplements during pregnancy. RESULTS: Dietary supplement use among Saudi women in pregnancy was high (71...
August 29, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28818585/-vitamin-k-in-the-neonate-recommendations-update
#18
J-M Hascoët, J-C Picaud, A Lapillonne, C Boithias-Guerot, P Bolot, E Saliba
Hemorrhagic disease of the newborn is not common but may be very serious, with cerebral, hepatic, or adrenal gland bleeding. Its prevention is based upon vitamin K1 administration from birth. Scientific studies to validate appropriate treatment policies are scarce, with recommendations coming from expert opinions, retrospective studies, or controversies on possible side effects. After analysis of recent literature data, we propose an oral administration of three doses of 2mg of vitamin K1 at birth, at discharge from the maternity ward, and at 1 month postnatal age for term infants...
August 14, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28818584/-neonatal-intoxication-to-vitamin-d-in-premature-babies-a-series-of-16%C3%A2-cases
#19
M Vierge, S Laborie, A Bertholet-Thomas, M-C Carlier, J-C Picaud, O Claris, J Bacchetta
INTRODUCTION: Preterm neonates are particularly at risk of vitamin D (25-D) deficiency. To prevent rickets and osteopenia in this population, international guidelines vary between 800 and 1000IU per day of vitamin D in Europe and recommend 400IU per day in the USA. Target levels of circulating 25-D are not well identified, with the lower target level 50-75nmol/L and the upper target level probably 120nmol/L. METHODS: Between 2013 and 2015, 16 premature infants (born<35WG) were referred to pediatric nephrology clinics because of symptoms secondary to 25-D overdose during the neonatal period...
August 14, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28771404/benign-neonatal-shudders-shivers-jitteriness-or-tremors-early-signs-of-vitamin-d-deficiency
#20
Millicent Collins, Michal Young
Jitteriness and tremors in the newborn period typically precipitate an extensive, invasive, and expensive search for the etiology. Vitamin D deficiency has not been historically included in the differential of tremors. We report a shivering, jittery newborn who was subjected to a battery of testing, with the only biochemical abnormality being vitamin D deficiency. A second case had chin tremors and vitamin D deficiency. Review of our patients suggests that shudders, shivers, jitteriness, or tremors may be the earliest sign of vitamin D deficiency in the newborn...
August 2017: Pediatrics
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