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https://www.readbyqxmd.com/read/28920035/anesthesia-management-of-a-patient-with-papillon-lefevre-syndrome-a-case-report
#1
Afshin Iranpour, Ata Mahmoodpoor
INTRODUCTION: Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive trait; it often requires some interventions with general anesthesia because of the accompanied complications. CASE PRESENTATION: We report a 19-year-old girl with palmoplantar hyperkeratosis who presented total loss of her teeth. She was candidate to mandibular bone graft and lower jaw dental implants under general anesthesia. CONCLUSIONS: There are only a few studies about perioperative management of these patients; however, the anesthesiologists should consider a few important issues during pre-operative and intra-operative management...
February 2017: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/28917560/outcomes-of-rescue-cardiopulmonary-support-for-periprocedural-acute-hemodynamic-decompensation-in-patients-undergoing-catheter-ablation-of-electrical-storm
#2
Andres Enriquez, Jackson Liang, Javier Gentile, Robert Schaller, Gregory Supple, David S Frankel, Fermin Garcia, Joyce Wald, Edo Y Birati, J Eduardo Rame, Christian Bermudez, David Callans, Francis Marchlinski, Pasquale Santangeli
BACKGROUND: In patients with ventricular tachycardia/fibrillation (VT/VF) electrical storm (ES) undergoing catheter ablation (CA), hypotension due to refractory VT/VF, use of anesthesia and cardiac stunning due to repeated ICD shocks might precipitate acute hemodynamic decompensation (AHD). OBJECTIVE: We evaluated the outcomes of emergent cardiopulmonary support with extracorporeal membrane oxygenation (ECMO) to rescue AHD in patients undergoing CA of ES. METHODS: Between 2010 and 2016, 21 patients with ES (VT in 11 and PVC-triggered VF in 10) were referred for CA and had periprocedural AHD requiring emergent ECMO support...
September 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28916246/pre-clinical-toxicology-considerations-for-vaccine-development
#3
REVIEW
Nabil Al-Humadi
Vaccine development requires pre-clinical toxicology studies, following good laboratory practice (GLP), before first in human (phase I) use. Many factors are critical in the final outcome of any pre-clinical toxicology study. The study design is one of these critical factors and should be carefully planned to avoid any false negative and/or false positive results. Preparation is another most critical factor in a successful study. Major changes in any procedure during the course of study should be avoided by all means...
September 12, 2017: Vaccine
https://www.readbyqxmd.com/read/28900757/low-incidence-of-postoperative-urinary-retention-with-the-use-of-a-nurse-led-bladder-scan-protocol-after-hip-and-knee-arthroplasty-a-retrospective-cohort-study
#4
N P Kort, Y Bemelmans, R Vos, M G M Schotanus
PURPOSE: Postoperative urinary retention (POUR), defined as the inability to empty the bladder voluntary after surgery, is a commonly reported complication. This study reports the incidence and possible risk factors for POUR after elective fast-track hip or knee arthroplasty when using a nurse-led bladder scan protocol. METHODS: This retrospective cohort study included data from 803 patients who underwent unilateral hip or knee arthroplasty. Patients' digital clinical records were reviewed for eligibility...
September 12, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28894068/-the-effects-of-30-minutes-of-pre-warming-on-core-body-temperature-systolic-blood-pressure-heart-rate-postoperative-shivering-and-inflammation-response-in-elderly-patients-with-total-hip-replacement-under-spinal-anesthesia-a-randomized-double-blind-controlled
#5
You Mi Cheon, Haesang Yoon
PURPOSE: This study was designed to determine the effects of pre-warming on core body temperature (CBT) and hemodynamics from the induction of spinal anesthesia until 30 min postoperatively in surgical patients who undergo total hip replacement under spinal anesthesia. Our goal was to assess postoperative shivering and inflammatory response. METHODS: Sixty-two surgical patients were recruited by informed notice. Data for this study were collected at a 1,300-bed university hospital in Incheon, South Korea from January 15 through November 15, 2013...
August 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28893727/development-of-a-virtual-reality-exposure-tool-as-psychological-preparation-for-elective-pediatric-day-care-surgery-methodological-approach-for-a-randomized-controlled-trial
#6
Robin Eijlers, Jeroen S Legerstee, Bram Dierckx, Lonneke M Staals, Johan Berghmans, Marc P van der Schroeff, Rene Mh Wijnen, Elisabeth Mwj Utens
BACKGROUND: Preoperative anxiety in children is highly prevalent and is associated with adverse outcomes. Existing psychosocial interventions to reduce preoperative anxiety are often aimed at distraction and are of limited efficacy. Gradual exposure is a far more effective way to reduce anxiety. Virtual reality (VR) provides a unique opportunity to gradually expose children to all aspects of the operating theater. OBJECTIVE: The aims of our study are (1) to develop a virtual reality exposure (VRE) tool to prepare children psychologically for surgery; and (2) to examine the efficacy of the VRE tool in a randomized controlled trial (RCT), in which VRE will be compared to care as usual (CAU)...
September 11, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28891234/retrospective-analysis-of-nonradiation-complications-in-dogs-undergoing-radiation-therapy
#7
John Farrelly, Qiuhu Shi
Dogs receiving radiation can develop complications unrelated to the radiation treatment. No study to date has described these complications in clinical patients undergoing multiple radiation therapy treatments. The purpose of this retrospective case-control study was to characterize the incidence and type of complications that occur in these dogs. A secondary goal was to evaluate whether patient and treatment characteristics could be identified to predict the risk of these complications. Medical records of 268 dogs receiving at least one radiation treatment at a single institution, between September, 2004 and June, 2007 were reviewed...
September 10, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28879336/the-use-of-general-anesthesia-to-facilitate-dental-treatment-in-adult-patients-with-special-needs
#8
REVIEW
Mathew Albert Wei Ting Lim, Gelsomina Lucia Borromeo
General anesthesia is commonly used to facilitate dental treatment in patients with anxiety or challenging behavior, many of whom are children or patients with special needs. When performing procedures under general anesthesia, dental surgeons must perform a thorough pre-operative assessment, as well as ensure that the patients are aware of the potential risks and that informed consent has been obtained. Such precautions ensure optimal patient management and reduce the frequency of morbidities associated with this form of sedation...
June 2017: J Dent Anesth Pain Med
https://www.readbyqxmd.com/read/28874164/radiation-free-cmr-diagnostic-heart-catheterization-in-children
#9
Kanishka Ratnayaka, Joshua P Kanter, Anthony Z Faranesh, Elena K Grant, Laura J Olivieri, Russell R Cross, Ileen F Cronin, Karin S Hamann, Adrienne E Campbell-Washburn, Kendall J O'Brien, Toby Rogers, Michael S Hansen, Robert J Lederman
BACKGROUND: Children with heart disease may require repeated X-Ray cardiac catheterization procedures, are more radiosensitive, and more likely to survive to experience oncologic risks of medical radiation. Cardiovascular magnetic resonance (CMR) is radiation-free and offers information about structure, function, and perfusion but not hemodynamics. We intend to perform complete radiation-free diagnostic right heart catheterization entirely using CMR fluoroscopy guidance in an unselected cohort of pediatric patients; we report the feasibility and safety...
September 6, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28867907/preemptive-analgesia-in-thumb-basal-joint-arthroplasty-immediate-postoperative-pain-with-preincision-versus-postincision-local-anesthesia
#10
Joseph T Labrum, Asif M Ilyas
Purpose  Currently no guidelines exist for the timing of the injection of anesthetics in surgeries performed under general anesthesia to minimize postoperative pain. To better understand the role of timing of the injection of local anesthesia in hand surgery performed under general anesthesia, we evaluated the effect of pre- versus postincisional local analgesic injection on immediate postoperative pain experience. We hypothesize that the preincisional (preemptive) injection will result in decreased immediate postoperative pain experience and analgesic use when compared with postincisional injection...
August 2017: Journal of Hand and Microsurgery
https://www.readbyqxmd.com/read/28866042/intracardiac-echocardiography-from%C3%A2-the%C3%A2-left-atrium-for-procedural-guidance-of-transcatheter-left-atrial-appendage%C3%A2-occlusion
#11
Kasper Korsholm, Jesper Møller Jensen, Jens Erik Nielsen-Kudsk
OBJECTIVES: The aim of this study was to compare the efficacy and safety of intracardiac echocardiography (ICE) from the left atrium (LA) with transesophageal echocardiography (TEE) for procedural guidance of transcatheter left atrial appendage occlusion (LAAO). BACKGROUND: TEE with general anesthesia is the current gold standard to guide LAAO. By the use of ICE from the LA, LAAO can be performed in local anesthesia and may potentially have advantages over TEE. METHODS: A single-center, cohort study of patients undergoing LAAO with the Amplatzer Cardiac Plug or Amulet (St...
August 24, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28852345/outside-in-vs-anteromedial-portal-drilling-during-primary-acl-reconstruction-comparison-at-two-years
#12
Tyler CarlLee, Zach Ries, Kyle Duchman, Yubo Gao, Brian Wolf, Annunziato Amendola, Carolyn Hettrich, Matthew Bollier
BACKGROUND: Anteromedial (AM) and outside-in (OI) are two commonly used techniques for drilling the femoral tunnel during anterior cruciate ligament reconstruction (ACLR). The purpose of this study was to compare clinical and radiographic outcomes of patients undergoing primary ACLR using either AM or OI femoral drilling with minimum two year follow-up. METHODS: Overall, 138 prospectively enrolled patients undergoing primary ACLR underwent AM or OI femoral drilling...
2017: Iowa Orthopaedic Journal
https://www.readbyqxmd.com/read/28852338/evaluating-different-clinical-diagnosis-of-anterior-cruciate-ligament-ruptures-in-providers-with-different-training-backgrounds
#13
Alexander Cm Chong, Chelsea Whitetree, Michael C Priddy, Parker R Zimmerman, Paul R Haeder, Daniel J Prohaska
INTRODUCTION: Previous studies have shown that provider training and the tests performed play a role in the accuracy of diagnosis of anterior cruciate ligament (ACL) injuries. The specific aim of the current study is to determine the examiner proficiency and accuracy in performing the different proactive tests of ACL rupture before and after the induction of anesthesia prior to a definitive surgical procedure. MATERIALS AND METHODS: A case series was performed from January of 2015 through July of 2015...
2017: Iowa Orthopaedic Journal
https://www.readbyqxmd.com/read/28852334/should-all-shoulder-dislocations-be-closed-reduced-assessment-of-risk-of-iatrogenic-injury-in-150-patients
#14
Olga Solovyova, Rachel Shakked, Nirmal C Tejwani
AIMS: The purpose of this study was to determine if there was an association between iatrogenic fractures and closed reduction of shoulder dislocations. PATIENTS AND METHODS: In a retrospective case series, 150 consecutive patients with acute first time shoulder dislocations were evaluated. Patient demographics, direction of dislocation, associated injuries, reduction methods, number of attempts, and type of anesthesia/analgesia were determined. Pre- and post-reduction radiographs and medical record were reviewed to identify the presence of proximal humerus fractures...
2017: Iowa Orthopaedic Journal
https://www.readbyqxmd.com/read/28845941/-ultrasound-guided-percutaneous-cryoablation-of-renal-tumors
#15
D V Enikeev, P V Glybochko, Yu G Alyaev, L M Rapoport, A V Amosov, T M Alekseeva, M E Enikeev, D G Tsarichenko, D V Chinenov, L D Kozmin, Z K Dzhalaev, M S Taratkin
INTRODUCTION: Surgery remains the gold-standard curative treatment for localized (T1) renal carcinoma. However, recent medical-technological advances have led to the development of new minimally invasive treatment options, one of which is percutaneous cryoablation. AIM: To assess the effectiveness and safety of ultrasound-guided percutaneous cryoablation of renal tumors. MATERIALS AND METHODS: The study comprised 12 patients aged 52 to 76 years who underwent ultrasound-guided percutaneous cryoablation of renal tumors from 2015 to 2017...
July 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28844125/stem-cell-therapy-for-avascular-necrosis-of-femoral-head-in-sickle-cell-disease-report-of-11-cases-and-review-of-literature
#16
Mir Sadat-Ali, Md Q Azam, Ezzat M Elshabouri, Ahmad M Tantawy, Sadananda Acharya
Background and Objective: Sickle cell disease (SCD) is quite common in eastern Saudi Arabia and Avascular necrosis of femoral head (ANFH) occurs in 30% of the young patients leading to early joint arthroplasty. This study was conducted to assess the benefits of injection of osteoblasts in the avascular lesions of the head of femur. Patients and Methods: A preset technique was used, 10 CC of bone marrow aspiration was performed under local anesthesia and aseptic technique...
August 31, 2017: International Journal of Stem Cells
https://www.readbyqxmd.com/read/28840505/anesthesia-in-per-oral-endoscopic-myotomy-a-large-tertiary-care-centre-experience
#17
Santosh Darisetty, Zaheer Nabi, Mohan Ramchandani, Radhika Chavan, Rama Kotla, D Nageshwar Reddy
BACKGROUND AND OBJECTIVES: Per-oral endoscopic myotomy (POEM) is safe and efficacious for the management of achalasia cardia (AC). POEM is usually performed under general anesthesia in an endoscopy suite or operating theatre. The current study was conducted with the aim to analyse anesthetic management of patients with AC who underwent POEM at our institution. METHODS: We retrospectively analysed the data of patients with AC who underwent POEM at our institution from January 2013 to September 2016...
August 24, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28830869/anesthesia-and-bariatric-surgery-gut-preparation-alter-plasma-acylcarnitines-reflective-of-mitochondrial-fat-and-branched-chain-amino-acid-oxidation
#18
Sudeepa Bhattacharyya, Mohamed Ali, William H Smith, Paul E Minkler, Maria S Stoll, Charles L Hoppel, Sean H Adams
The period around bariatric surgery offers a unique opportunity to characterize metabolism responses to dynamic shifts in energy, gut function, and anesthesia. We analyzed plasma acylcarnitines in obese women (n=17) sampled in the overnight fasted/postabsorptive state ca. 1-2 weeks prior to surgery (Condition A), the morning of surgery (prior restriction to a 48 hr. clear liquid diet coupled in some cases a standard polyethylene glycol gut evacuation: Condition B), and following induction of anesthesia (Condition C)...
August 22, 2017: American Journal of Physiology. Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28826611/analysis-of-temperature-increase-in-swine-gingiva-after-exposure-to-a-polywave-%C3%A2-led-light-curing-unit
#19
Cristiane Maucoski, Driellen Christine Zarpellon, Fabio Andre Dos Santos, Leandro Cavalcante Lipinski, Eduardo Bauml Campagnoli, Frederick Allen Rueggeberg, Cesar Augusto Galvão Arrais
OBJECTIVE: This study evaluated the temperature increase in swine gingival temperature after exposure to light emitted by a Polywave(®) LED light curing unit (LCU, Bluephase 20i, Ivoclar Vivadent). METHODS: After local Ethics Committee approval (protocol 711/2015), 40 pigs were subjected to general anesthesia and the LCU tip was placed 5mm from the buccal gingival tissue (GT) close to lower lateral incisors. A thermocouple probe (Thermes WFI, Physitemp) was inserted into the gingival sulcus before and immediately after exposure to light...
August 18, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28820497/anesthetic-agents-of-plant-origin-a-review-of-phytochemicals-with-anesthetic-activity
#20
REVIEW
Hironori Tsuchiya
The majority of currently used anesthetic agents are derived from or associated with natural products, especially plants, as evidenced by cocaine that was isolated from coca (Erythroxylum coca, Erythroxylaceae) and became a prototype of modern local anesthetics and by thymol and eugenol contained in thyme (Thymus vulgaris, Lamiaceae) and clove (Syzygium aromaticum, Myrtaceae), respectively, both of which are structurally and mechanistically similar to intravenous phenolic anesthetics. This paper reviews different classes of phytochemicals with the anesthetic activity and their characteristic molecular structures that could be lead compounds for anesthetics and anesthesia-related drugs...
August 18, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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