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osteoarthritis in africans

Eleanor E Friedman, Wayne A Duffus
OBJECTIVES: To examine sociodemographic factors and chronic health conditions of people living with HIV (PLWHIV/HIV+) at least 65 years old and compare their chronic disease prevalence with beneficiaries without HIV. DESIGN: National fee-for-service Medicare claims data (parts A and B) from 2006 to 2009 were used to create a retrospective cohort of beneficiaries at least 65 years old. METHODS: Beneficiaries with an inpatient or skilled nursing facility claim, or outpatient claims with HIV diagnosis codes were considered HIV+...
October 23, 2016: AIDS
Anthony Dugarte, Sahil Bharwani, HoJun Yoo, Alexander Vondra Boiwka, Charles C Yu, Navkirat S Bajwa, Jason O Toy, Jonathan E Tang, Uri Ahn, Nicholas Ahn
Surgical models have best shown the relationship between ankle and mid-foot osteoarthritis, although findings regarding the calcaneocuboid joint have varied. To the authors' knowledge, no studies have evaluated the relationship between degenerative changes across the tibiotalar and calcaneocuboid joints. The goal of this study was to determine whether such a relationship exists and which joint degenerates first. A single examiner evaluated 694 tibiotalar and calcaneocuboid joints to determine the presence of osteoarthritis...
August 30, 2016: Orthopedics
Leah A Schrubbe, Scott G Ravyts, Bernadette C Benas, Lisa C Campbell, Crystal W Cené, Cynthia J Coffman, Alexander H Gunn, Francis J Keefe, Caroline T Nagle, Eugene Z Oddone, Tamara J Somers, Catherine L Stanwyck, Shannon S Taylor, Kelli D Allen
BACKGROUND: African Americans bear a disproportionate burden of osteoarthritis (OA), with higher prevalence rates, more severe pain, and more functional limitations. One key barrier to addressing these disparities has been limited engagement of African Americans in the development and evaluation of behavioral interventions for management of OA. Pain Coping Skills Training (CST) is a cognitive-behavioral intervention with shown efficacy to improve OA-related pain and other outcomes. Emerging data indicate pain CST may be a promising intervention for reducing racial disparities in OA symptom severity...
2016: BMC Musculoskeletal Disorders
Eleanor E Friedman, Wayne A Duffus
OBJECTIVES: To examine sociodemographic factors and chronic health conditions of people living with HIV (PLWHIV/HIV+) at least 65 years old and compare their chronic disease prevalence with beneficiaries without HIV. DESIGN: National fee-for-service Medicare claims data (parts A and B) from 2006 to 2009 were used to create a retrospective cohort of beneficiaries at least 65 years old. METHODS: Beneficiaries with an inpatient or skilled nursing facility claim, or outpatient claims with HIV diagnosis codes were considered HIV+...
October 23, 2016: AIDS
Virginia B Kraus, David E Hargrove, David J Hunter, Jordan B Renner, Joanne M Jordan
OBJECTIVE: To establish reference intervals for osteoarthritis (OA)-related biomarkers used in the Foundation for the National Institutes of Health (FNIH) OA Biomarkers Consortium Project. METHODS: A total of 129 'multijoint controls' were selected from 2722 African-American and Caucasian men and women in the Johnston County Osteoarthritis Project. The majority (79%) of those eligible (with biospecimens and baseline data) also had one or more follow-up evaluations 5-15 years later...
June 24, 2016: Annals of the Rheumatic Diseases
M M Saw, T Kruger-Jakins, N Edries, R Parker
BACKGROUND: A major challenge facing those with late stage osteoarthritis is delayed surgery due to waiting lists. In South Africa patients wait years for a hip/knee arthroplasty. Affected patients require effective management to address their pain, especially while awaiting surgery. Existing literature is mostly available from high income countries exploring effects of interventions during short waiting periods. Research is warranted in low income countries where long waiting periods are common...
2016: BMC Musculoskeletal Disorders
A S Moss, L B Murphy, C G Helmick, T A Schwartz, K E Barbour, J B Renner, W Kalsbeek, J M Jordan
OBJECTIVE: Estimate annual incidence rates (IRs) of hip symptoms and three osteoarthritis (OA) outcomes (radiographic, symptomatic, and severe radiographic) overall and by race, sociodemographic characteristics, and hip OA risk factors. DESIGN: Analyze baseline (1991-1997) and first follow-up (1999-2003) data (n = 1446) from the Johnston County Osteoarthritis Project, a population-based, prospective study of adults ≥45 years in North Carolina. Hip symptoms were pain, aching, and/or stiffness on most days, or groin pain...
September 2016: Osteoarthritis and Cartilage
Ernest R Vina, Diane Richardson, Elina Medvedeva, C Kent Kwoh, Aliya Collier, Said A Ibrahim
BACKGROUND: A TKA is the most effective and cost-effective surgical option for moderate to severe osteoarthritis (OA) of the knee. Yet, black patients are less willing to undergo knee replacement surgery than white patients. Decision aids help people understand treatment options and consider the personal importance of possible benefits and harms of treatments, including TKA. QUESTIONS/PURPOSES: We asked: (1) Does a patient-centered intervention consisting of a decision aid for knee OA and motivational interviewing improve the proportion of referrals of blacks with knee OA to orthopaedic surgery? (2) Does the intervention increase patients' willingness to undergo TKA? METHODS: Adults who self-identified as black who were at least 50 years old with moderate to severe knee OA were enrolled from urban primary care clinics in a two-group randomized, controlled trial...
August 2016: Clinical Orthopaedics and related Research
Janiece L Walker, Tracie C Harrison, Adama Brown, Roland J Thorpe, Sarah L Szanton
BACKGROUND: Middle-aged and older African American women experience disproportionate rates of functional limitations and disability from osteoarthritis (OA) compared to other racial ethnic groups; however, little is known about what factors contribute to this disparity within African American women. OBJECTIVE: To examine factors associated with physical function and disability among African American women ages 50-80 with OA using the disablement process model. METHODS: This descriptive study included 120 African American women with OA from the Southwestern region of the United States...
July 2016: Disability and Health Journal
Bhushan R Deshpande, Jeffrey N Katz, Daniel H Solomon, Edward H Yelin, David J Hunter, Stephen P Messier, Lisa G Suter, Elena Losina
OBJECTIVE: The prevalence of symptomatic knee osteoarthritis (OA) has been increasing over the past several decades in the United States concurrent with an aging population and the growing obesity epidemic. We quantify the impact of these factors on the number of persons with symptomatic knee OA in the first decades of 21st century. METHODS: We calculated prevalence of clinically diagnosed symptomatic knee OA from the National Health Interview Survey 2007-08 and derived the proportion with advanced disease (Kellgren-Lawrence grades 3-4) using the Osteoarthritis Policy Model, a validated simulation model of knee OA...
March 25, 2016: Arthritis Care & Research
Celine Ward, Krysta Contino, Akshar Patel, Eben Eno Mbei, Satyajeet Roy, Krystal Hunter, Shivani Gandhi
BACKGROUND: Low serum 25-hydroxyvitamin D [25(OH)D] and osteoarthritis (OA) are commonly found in patients followed up in a primary care office. Clear evidence to support the link between 25-hydroxyvitamin D levels and OA is lacking. AIM: To describe the association of serum 25-hydroxyvitamin D status in patients with OA in the primary care office. MATERIALS AND METHODS: We reviewed the records of 1,455 patients seen in our primary care office between November 2013 and October 2014...
January 2016: North American Journal of Medical Sciences
M Kretzschmar, U Heilmeier, A Yu, G B Joseph, F Liu, M Solka, C E McCulloch, M C Nevitt, T M Link
OBJECTIVES: To investigate the change in cartilage T2 values and structural degeneration in knee joints over 72 months in women of African American (AA) vs Caucasian American (CA) ethnicity. METHODS: Knee 3T magnetic resonance imaging (MRIs) from baseline, 24, 48 and 72 months visits of 100 AA and 100 CA women from the Osteoarthritis Initiative (OAI) were assessed for cartilage T2 values and whole-organ magnetic resonance imaging (WORMS) score. Subjects were pair-matched by age, body mass index (BMI), Kellgren-Lawrence (KL) score, clinical site and subcohort within the OAI...
August 2016: Osteoarthritis and Cartilage
William Mayers, Brian Schwartz, Aaron Schwartz, Vincent Moretti, Wayne Goldstein, Ritesh Shah
PURPOSE: While a majority of total hip arthroplasty (THA) is performed for osteoarthritis (OA), a significant portion is performed in the setting of avascular necrosis (AVN). The purpose of this study is to evaluate recent trends, patient demographics, and in hospital outcomes for primary THA in the setting of AVN in the United States. METHODS: The National Hospital Discharge Survey database was searched for patients admitted to US hospitals after a primary THA for the years 2001-2010...
September 2016: International Orthopaedics
Bridget Foley, Rebecca J Cleveland, Jordan B Renner, Joanne M Jordan, Amanda E Nelson
BACKGROUND: To identify baseline radiographic features that predict hip osteoarthritis (HOA) progression, and to explore differences in these associations by race. METHODS: Radiographs from the community-based Johnston County OA Project were scored using Kellgren-Lawrence (KL) grade and for presence and location of joint space narrowing (JSN), osteophytes, and subchondral changes. Associations between these features and HOA progression (increase of at least 1 KL grade, interval hip replacement, range of motion [ROM, a reduction of ≥10° in internal rotation], or disability [increase of ≥0...
2015: Arthritis Research & Therapy
C Kent Kwoh, Ernest R Vina, Yona K Cloonan, Michael J Hannon, Robert M Boudreau, Said A Ibrahim
INTRODUCTION: Patient preferences contribute to marked racial disparities in the utilization of total knee replacement (TKR). The objectives of this study were to identify the determinants of knee osteoarthritis (OA) patients' preferences regarding TKR by race and to identify the variables that may mediate racial differences in willingness to undergo TKR. METHODS: Five hundred fourteen White (WH) and 285 African-American (AA) patients with chronic knee pain and radiographic evidence of OA participated in the study...
December 3, 2015: Arthritis Research & Therapy
H An, J S Marron, T A Schwartz, J B Renner, F Liu, J A Lynch, N E Lane, J M Jordan, A E Nelson
INTRODUCTION: Hip shape is a risk factor for the development of hip osteoarthritis (OA), and current methods to assess hip shape from radiographs are limited; therefore this study explored current and novel methods to assess hip shape. METHODS: Data from a prior case-control study nested in the Johnston County OA Project were used, including 382 hips (from 342 individuals). Hips were classified by radiographic hip OA (RHOA) status as RHOA cases (baseline Kellgren Lawrence grade [KLG] 0 or 1, follow-up [mean 6 years] KLG ≥ 2) or controls (KLG = 0 or 1 at both baseline and follow-up)...
April 2016: Osteoarthritis and Cartilage
Daniel L Riddle, Mateusz Makowski
OBJECTIVE: Knee pain location is routinely assessed in clinical practice. We determined the patterns of patient-reported pain locations for persons with knee osteoarthritis (OA). We also examined associations between knee pain patterns and severity of self-reported pain with activity and self-reported functional status. METHODS: The Osteoarthritis Initiative data were used to examine reports of pain location (localized, regional, or global) and type and extent of knee OA...
December 2015: Journal of Rheumatology
A E Nelson, J L Stiller, X A Shi, K M Leyland, J B Renner, T A Schwartz, N K Arden, J M Jordan
OBJECTIVES: We sought to describe the effect of alterations in hip morphology with respect to worsening hip OA in a community-based sample including African American (AA) and white men and women. METHODS: This nested case-control study defined case hips as Kellgren Lawrence grade (KLG) <3 on baseline supine pelvis radiographs and KLG ≥3 or THR for OA at the 1st or 2nd follow-up visit (mean 6 and 13 years, respectively); control hips had KLG <3 at both visits, with gender/race distribution similar to cases...
March 2016: Osteoarthritis and Cartilage
Toni L Glover, Ann L Horgas, Roger B Fillingim, Burel R Goodin
Diagnostic imaging of disease severity has been found thus far to be a relatively modest predictor of knee osteoarthritis (OA) pain and disability, suggesting that other factors likely contribute to clinical symptoms in this condition. Recent evidence suggests that sensitization of the peripheral and central pathways that process nociceptive information (i.e., pain sensitization) is an important contributor to knee OA clinical symptoms. Furthermore, low levels of vitamin D have been found to be associated with the presence of pain sensitization, as well as the overall experience of clinical pain severity in knee OA...
2015: Pain Management
Linda M Gerber, Ya-Lin Chiu, Mohamud Verjee, Hassan Ghomrawi
OBJECTIVE: The prevalence of osteoarthritis (OA) and rheumatoid arthritis (RA) has been poorly documented in the Middle East and North African region, including the State of Qatar. Given that musculoskeletal pain is commonly reported among midlife women, we evaluated the association between self-report of either OA or RA and health-related quality of life (HRQoL) among midlife women in Qatar. In addition, HRQoL among women in Qatar was compared with that of women in the Study of Women's Health Across the Nation (SWAN)...
March 2016: Menopause: the Journal of the North American Menopause Society
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