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https://www.readbyqxmd.com/read/28823099/evidence-of-dysexecutive-syndrome-in-patients-with-acromegaly
#1
Shaobo Shan, Lingling Fang, Jia Huang, Raymond C K Chan, Guijun Jia, Weiqing Wan
PURPOSE: This study aimed to explore different aspects of executive function in patients with acromegaly and investigate the cause of dysexecutive syndrome in these patients. METHODS: We conducted five typical executive function tests (Stroop test, verbal fluency [VF] test, Hayling Sentence Completion Test [HSCT], N-back test, and Sustained Attention to Response Task [SART]) on 42 acromegalic patients and 42 strictly matched healthy controls. Comparative analyses were conducted for five major executive function domains...
August 19, 2017: Pituitary
https://www.readbyqxmd.com/read/28822983/impulsivity-in-parkinson-s-disease-is-associated-with-altered-subthalamic-but-not-globus-pallidus-internus-activity
#2
Peter Justin Rossi, Jonathan B Shute, Enrico Opri, Rene Molina, Corinna Peden, Oscar Castellanos, Kelly D Foote, Aysegul Gunduz, Michael S Okun
BACKGROUND: A significant subset of patients with Parkinson's disease (PD) suffer from impulse control disorders (ICDs). A hallmark feature of many ICDs is the pursuit of rewarding behaviours despite negative consequences. Recent evidence implicates the subthalamic nucleus (STN) and globus pallidus internus (GPi) in reward and punishment processing, and deep brain stimulation (DBS) of these structures has been associated with changes in ICD symptoms. METHODS: We tested the hypothesis that in patients with PD diagnosed with ICD, neurons in the STN and GPi would be more responsive to reward-related stimuli and less responsive to loss-related stimuli...
August 19, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28822914/motor-correlates-of-phantom-limb-pain
#3
Sanne Kikkert, Melvin Mezue, David Henderson Slater, Heidi Johansen-Berg, Irene Tracey, Tamar R Makin
Following amputation, individuals ubiquitously report experiencing lingering sensations of their missing limb. While phantom sensations can be innocuous, they are often manifested as painful. Phantom limb pain (PLP) is notorious for being difficult to monitor and treat. A major challenge in PLP management is the difficulty in assessing PLP symptoms, given the physical absence of the affected body part. Here, we offer a means of quantifying chronic PLP by harnessing the known ability of amputees to voluntarily move their phantom limbs...
July 25, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28822879/patient-recall-of-specific-cognitive-therapy-contents-predicts-adherence-and-outcome-in-adults-with-major-depressive-disorder
#4
Lu Dong, Xin Zhao, Stacie L Ong, Allison G Harvey
The current study examined whether and which specific contents of patients' memory for cognitive therapy (CT) were associated with treatment adherence and outcome. Data were drawn from a pilot RCT of forty-eight depressed adults, who received either CT plus Memory Support Intervention (CT + Memory Support) or CT-as-usual. Patients' memory for treatment was measured using the Patient Recall Task and responses were coded into cognitive behavioral therapy (CBT) codes, such as CBT Model and Cognitive Restructuring, and non-CBT codes, such as individual coping strategies and no code...
August 10, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28822862/testing-the-performance-of-superhydrophobic-aluminum-surfaces
#5
F Javier Montes Ruiz-Cabello, Pablo F Ibáñez-Ibáñez, J Francisco Gómez-Lopera, José Martínez-Aroza, Miguel Cabrerizo-Vílchez, Miguel A Rodríguez-Valverde
The analysis of wetting properties of superhydrophobic surfaces may be a difficult task due to the restless behavior of drops on this type of surfaces and the limitations of goniometry for high contact angles. A method to validate the performance of superhydrophobic surfaces, rather than standard goniometry, is required. In this work, we used bouncing drop dynamics as a useful tool to predict the water repellency of different superhydrophobic surfaces. From bouncing drop experiments conducted over a wide range of superhydrophobic surfaces, we found that those surfaces with a proper roughness degree and homogeneous chemical composition showed higher water-repellency...
August 12, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28822751/using-multi-level-bayesian-lesion-symptom-mapping-to-probe-the-body-part-specificity-of-gesture-imitation-skills
#6
Elisabeth I S Achilles, Peter H Weiss, Gereon R Fink, Ellen Binder, Cathy J Price, Thomas M H Hope
Past attempts to identify the neural substrates of hand and finger imitation skills in the left hemisphere of the brain have yielded inconsistent results. Here, we analyse those associations in a large sample of 257 left hemisphere stroke patients. By introducing novel Bayesian methods, we characterise lesion symptom associations at three levels: the voxel-level, the single-region level (using anatomically defined regions), and the region-pair level. The results are inconsistent across those three levels and we argue that each level of analysis makes assumptions which constrain the results it can produce...
August 16, 2017: NeuroImage
https://www.readbyqxmd.com/read/28822742/strategy-set-shifting-and-response-inhibition-in-adult-rats-exposed-to-an-environmental-polychlorinated-biphenyl-mixture-during-adolescence
#7
Supida Monaikul, Paul Eubig, Stan Floresco, Susan Schantz
Converging evidence from studies with animal models and humans suggests that early developmental exposure to polychlorinated biphenyls (PCBs) leads to deficits in cognitive flexibility and inhibitory control. These processes are mediated to a large extent by the prefrontal cortex, thus we examined the effects of PCB exposure during adolescence-a period of robust prefrontal cortical development-on both processes. Specifically, we used operant set-shifting and differential reinforcement of low rates of responding (DRL) tasks to assess cognitive flexibility and response inhibition, respectively...
August 16, 2017: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/28822715/reproductive-outcomes-of-segmented-in-vitro-fertilization-in-patients-diagnosed-with-endometriomas
#8
Kemal Ozgur, Hasan Bulut, Murat Berkkanoglu, Kevin Coetzee
STUDY OBJECTIVE: To assess the impact of ovarian endometriomas on endometrial receptivity in frozen embryo transfers (FET) of segmented in vitro fertilization (IVF) cycles. DESIGN: Retrospective, matched-control study (Canadian Task Force Classification II-2). SETTING: A single, private assisted reproductive technology center. PATIENTS: Thirty patients diagnosed with unilateral or bilateral endometrioma were compared with 60 patients without endometrioma from 1,894 patients who underwent segmented IVF treatment between September 2014 and September 2016...
August 16, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28822703/turning-the-screw-even-further-to-increase-microparticle-retention-and-ocular-bioavailability-of-associated-drugs-the-bioadhesion-goal
#9
J Rodríguez Villanueva, L Rodríguez Villanueva
Ocular drug delivery is one of the most fascinating and challenging tasks facing pharmaceutical researchers. Improving drug ocular residence time and/or penetration is complex. Microparticles (MP) provide interesting opportunities to increase ocular bioavailability of drugs and patient compliance brought about by decreased frequency of dosing. However, sustained-release microsphere formulation would fail to accomplish the task of long-lasting drug release unless microspheres remained for a prolonged period at the site of action...
August 16, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28822694/sex-and-the-housing-effects-on-behavior-cortisol-levels-and-weight-in-zebrafish
#10
Gustavo Kellermann Reolon, Gabriela Madalena de Melo, João Gabriel Dos Santos da Rosa, Leonardo José Gil Barcellos, Carla Denise Bonan
Studies with zebrafish use acclimatizing periods of at least one week immediately before the experiments. During this time, animals can be housed in sexually segregated conditions (only females or males in the tank) or in mixed-sex conditions (both sexes in the tank). The influence of sex and housing conditions regarding the presence of one or two sexes is largely unknown in zebrafish. Our aim was to evaluate the influence that sex and housing regarding the sex of animals had in the open tank task, in the inhibitory avoidance memory test, in cortisol levels and weight in zebrafish...
August 16, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28822621/chondrosarcoma-of-the-epiglottis-a-case-report-and-literature-review
#11
REVIEW
Jonathan Choi, Harish Dharmarajan, Andrew Victores, Ashley Wenaas, Julina Ongkasuwan
BACKGROUND: Laryngeal chondrosarcoma (LCS) is an exceedingly rare malignancy and least frequently reported in the epiglottis. METHODS AND RESULTS: We report a case of a 71-year-old male smoker who presented with sore throat, dysphagia, and odynophagia for 3 months. Computed tomography scan revealed an inhomogeneously enhancing necrotic mass emanating from the right epiglottis and traveling along the aryepiglottic fold. The mass was removed via endoscopic en bloc laser resection...
August 16, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28822580/otologic-skills-training
#12
REVIEW
Gregory J Wiet, Mads Sølvsten Sørensen, Steven Arild Wuyts Andersen
This article presents a summary of the current simulation training for otologic skills. There is a wide variety of educational approaches, assessment tools, and simulators in use, including simple low-cost task trainers to complex computer-based virtual reality systems. A systematic approach to otologic skills training using adult learning theory concepts, such as repeated and distributed practice, self-directed learning, and mastery learning, is necessary for these educational interventions to be effective...
August 16, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28822579/facilitation-and-debriefing-in-simulation-education
#13
REVIEW
Sarah N Bowe, Kaalan Johnson, Liana Puscas
Successful simulation requires effective facilitation and debriefing to achieve educational goals. Simulation educational methods are diverse, ranging from partial task training to complicated, interdisciplinary team training. Various debriefing models have emerged based on method of instruction, learner experience, time and equipment capability, and physical facilities. The general structure of most debriefing sessions focuses on participant reactions, followed by analysis, and ending with a discussion of lessons learned...
August 16, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28822506/innovation-information-technology-and-task-sharing-for-management-of-burden-of-hypertension-in-india
#14
Anunay Gupta, Ambuj Roy
No abstract text is available yet for this article.
July 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28822474/the-effect-of-augmented-feedback-and-expertise-on-spinal-manipulation-skills-an-experimental-study
#15
Mégane Pasquier, Charlène Cheron, Claude Dugas, Arnaud Lardon, Martin Descarreaux
OBJECTIVES: The purpose of this study was to investigate the combined effect of augmented feedback and expertise on the performance and retention of basic motor learning spinal manipulation skills. METHODS: A total of 103 chiropractic students with various training expertise were recruited for the study. Participants were evaluated at baseline, immediately after trials of augmented feedback practice and 1 week later. During all 3 assessments, students were asked to perform several trials of the same spinal manipulation, for which the maximum preload force, onset of thrust, thrust duration, force and peak force, thrust duration, rate of force application, and any drop in preload force were calculated...
July 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28822460/-french-society-for-biological-psychiatry-and-neuropsychopharmacology-and-fondation-fondamental-task-force-formal-consensus-for-the-management-of-treatment-resistant-depression
#16
T Charpeaud, J-B Genty, S Destouches, A Yrondi, S Lancrenon, N Alaïli, F Bellivier, D Bennabi, T Bougerol, V Camus, T D'amato, O Doumy, F Haesebaert, J Holtzmann, C Lançon, M Lefebvre, F Moliere, I Nieto, R Richieri, L Schmitt, F Stephan, G Vaiva, M Walter, M Leboyer, W El-Hage, E Haffen, P-M Llorca, P Courtet, B Aouizerate
Major depression represents among the most frequent psychiatric disorders in the general population with an estimated lifetime prevalence of 16-17%. It is characterized by high levels of comorbidities with other psychiatric conditions or somatic diseases as well as a recurrent or chronic course in 50 to 80% of the cases leading to negative repercussions on the daily functioning, with an impaired quality of life, and to severe direct/indirect costs. Large cohort studies have supported that failure of a first-line antidepressant treatment is observed in more than 60% of patients...
September 2017: L'Encéphale
https://www.readbyqxmd.com/read/28822349/the-icrc-am-pm-database-challenges-in-forensic-data-management-in-the-humanitarian-sphere
#17
Ute Hofmeister, Shuala S Martin, Carlos Villalobos, Juliana Padilla, Oran Finegan
Large-scale forensic investigations should include a robust data management system with software capable of performing all tasks relevant to achieving the objectives of the investigation. Data management involves the collection, archiving, analysis and reporting of data. A successful data management system requires the development of protocols, procedures and policies, such as on data protection, as well as tools, including software. Adequate training for staff is also required, along with strict quality control and assurance regimens...
July 27, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28822296/developmental-changes-in-the-mental-transformation-of-spatial-arrays
#18
Christos S Michaelides, Marios N Avraamides
An experiment was conducted to investigate the spatial memory and transformation of spatial relations in a sample of 7-, 9-, and 11-year-olds and to compare their performance with that of adults. Four pictures of animals were presented at different locations on the outline of a circle. Participants were instructed to memorize the array of locations and then, in a direct retrieval task, to reconstruct it from memory on a piece of paper that included only the circle outline. Then, in the transformation task, participants were asked to randomly place one of the animals at a new position around the circle and then to place the remaining three animals so that object-to-object locations were preserved...
August 16, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28822262/evaluating-the-influence-of-at-risk-alcohol-use-on-factors-associated-with-smoking-cessation-combining-laboratory-and-ecological-momentary-assessment
#19
Joanna R Sells, Andrew J Waters, R Ross MacLean
OBJECTIVE: Most smokers want to quit but most cessation attempts end in failure. Alcohol consumption is associated with smoking behavior and relapse. We examined the associations between severity of drinking and psychological processes during a cessation attempt in the laboratory and during a quit attempt. METHODS: Smokers (N=209) enrolled in a smoking cessation study were followed from 2 weeks pre-quit through 4 weeks post-quit. Participants scoring 0-7 and 8-15 on the Alcohol Use Disorders Identification Test (AUDIT) were classified as low-risk and high-risk drinkers, respectively...
July 4, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28822099/insecticide-toxicity-to-the-borer-neoleucinodes-elegantalis-guen%C3%A3-e-lepidoptera-crambidae-developmental-and-egg-laying-effects
#20
R S Silva, L P Arcanjo, J R S Soares, D O Ferreira, J E Serrão, J C Martins, Á H Costa, M C Picanço
Neoleucinodes elegantalis (Guenée) (Lepidoptera: Crambidae) is one of the major pests of solanaceous plants in South America. It is considered a great threat by the European and Mediterranean Plant Protection Organization due to the serious economic damage that it causes on tomato farms; therefore, controlling this pest is a challenging task in South America. Controlling N. elegantalis at the egg stage is the best way to prevent it from damaging crops; however, thorough studies about the effectiveness of chemicals on the different life stages of this insect pest are lacking...
August 18, 2017: Neotropical Entomology
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