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Keywords perinatal infection and develo...

perinatal infection and development outcome

https://read.qxmd.com/read/38217616/risk-factors-for-postoperative-complications-in-preterm-infants-with-surgical-necrotizing-enterocolitis-and-associated-outcomes
#21
JOURNAL ARTICLE
P P Garg, R Riddick, M A Y Ansari, I Pittman, M R Ladd, P Porcelli, P M Garg
BACKGROUND: We aim to determine clinical risk factors for postoperative complications in preterm infants with surgical necrotizing enterocolitis (NEC) or spontaneous intestinal perforation (SIP). METHODS: A retrospective cohort study of preterm infants with surgical NEC or SIP to compare clinical factors between those with and without postoperative complications. RESULTS: 78/109 (71.5%) infants had any complication following surgical NEC. Adhesions (20/35, 57...
January 8, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38196206/effects-of-covid-19-virus-infection-on-pregnancy-outcomes-a-systematic-review-and-meta-analysis
#22
JOURNAL ARTICLE
Upendra Pandit, Niki Shrestha, Gayatri Khanal
BACKGROUND: Pregnant mothers are more susceptible to Corona Virus Diseases 2019 (COVID-19) during pandemic. Our aim was to find out the effects of the COVID-19 infection on pregnancy outcomes compared to mothers without COVID-19 diseases. METHODS: The review protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO) and obtained number of the Centre for review and Dissemination (CRD42021272321). The observational studies from September 1st to October 31, 2021 were searched with Medical Subject Heading (MeSH) term in the databases...
December 13, 2023: Journal of Nepal Health Research Council
https://read.qxmd.com/read/38134339/fetal-growth-restriction-a-comprehensive-review-of-major-guidelines
#23
REVIEW
Sonia Giouleka, Ioannis Tsakiridis, Apostolos Mamopoulos, Ioannis Kalogiannidis, Apostolos Athanasiadis, Themistoklis Dagklis
IMPORTANCE: Fetal growth restriction (FGR) is a common pregnancy complication and a significant contributor of fetal and neonatal morbidity and mortality, mainly due to the lack of effective screening, prevention, and management policies. OBJECTIVE: The aim of this study was to review and compare the most recently published influential guidelines on the management of pregnancies complicated by FGR. EVIDENCE ACQUISITION: A descriptive review of guidelines from the American College of Obstetricians and Gynecologists (ACOG), the Society for Maternal-Fetal Medicine, the International Federation of Gynecology and Obstetrics, the International Society of Ultrasound in Obstetrics and Gynecology, the Royal College of Obstetricians and Gynecologists, the Society of Obstetricians and Gynecologists of Canada (SOGC), the Perinatal Society of Australia and New Zealand, the Royal College of Physicians of Ireland, the French College of Gynecologists and Obstetricians (FCGO), and the German Society of Gynecology and Obstetrics on FGR was carried out...
November 2023: Obstetrical & Gynecological Survey
https://read.qxmd.com/read/38132664/perinatal-stressors-and-consequences-for-neonates-with-critical-congenital-heart-disease
#24
JOURNAL ARTICLE
Christina Ronai, Isabel Katlaps, Amanda Kim, Amy M Valent, Kent L Thornburg, Erin Madriago
INTRODUCTION: The prenatal diagnosis of congenital heart disease (CHD) is a traumatic event that can cause expectant parents to experience anxiety, depression, and toxic stress. Prenatal exposure to stress may impact neonatal postoperative outcomes. In addition, expectant parents may have other psychosocial stressors that may compound maternal stress. We investigated the relationship between stress in pregnancies complicated by prenatally diagnosed CHD and their neonatal outcomes. METHODS: A pilot retrospective cohort study of pregnancies with prenatally diagnosed critical CHD (2019-2021) was performed...
December 15, 2023: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/38118226/placental-pathology-in-a-large-swedish-cohort-of-sars-cov-2-infected-mothers
#25
JOURNAL ARTICLE
Lisa Fredriksson, Evelina Tidholm Qvist, Meeli Sirotkina, Karin Pettersson, Nikos Papadogiannakis
INTRODUCTION: SARS-CoV-2 placentitis is associated with placental destruction and insufficiency and can affect perinatal outcome. The aim of the current study was to contribute with increased knowledge regarding placental histology in maternal SARS-CoV-2 infection during the pregnancy, as well as the correlation to the severity of maternal SARS-CoV-2 infection. MATERIAL AND METHODS: This retrospective observational study included 116 women who had a verified SARS-CoV-2 infection during pregnancy and gave birth between April 2020 and February 2022 in the Stockholm region, Sweden...
December 15, 2023: Placenta
https://read.qxmd.com/read/38098237/a-multivariable-prediction-model-for-intra-amniotic-infection-in-patients-with-preterm-labor-and-intact-membranes-including-a-point-of-care-system-that-measures-amniotic-fluid-mmp-8
#26
JOURNAL ARTICLE
Teresa Cobo, Silvia Ferrero, Anna Haavisto, Paula Luokola, Ana B Sanchez-Garcia, Jordi Bosch, Amadeu Gené, Clara Murillo, Claudia Rueda, Bernardino González-de la Presa, Susana Santamaria, Júlia Ponce, David Boada, Montse Palacio
OBJECTIVES: Among patients with preterm labor and intact membranes (PTL), those with intra-amniotic infection (IAI) present the highest risk of adverse perinatal outcomes. Current identification of IAI, based on microbiological cultures and/or polymerase chain reaction amplification of the 16S ribosomal RNA gene, delay diagnosis and, consequently, antenatal management. The aim to of the study was to assess the performance of a multivariable prediction model for diagnosing IAI in patients with PTL below 34...
December 15, 2023: Journal of Perinatal Medicine
https://read.qxmd.com/read/38090413/a-narrative-review-of-maternal-and-perinatal-outcomes-of-dengue-in-pregnancy
#27
REVIEW
Shivani Ahuja, Pramita Muntode Gharde
Dengue is one of the most prevalent mosquito-borne diseases in today's world, especially in India. It is an important health problem and it is very important to address it promptly. Acquiring dengue during pregnancy can have a considerable influence on the health of the mother and baby. In dengue fever, moderate to severe consequences can occur in the mother. Severe dengue poses additional risks to pregnant women due to the likelihood of sequelae such as severe dengue, preeclampsia, gestational hypertension, anemia, maternal death and hemolysis, organ dysfunction, and even death...
November 2023: Curēus
https://read.qxmd.com/read/38072494/cohort-profile-the-pregnancy-risk-infant-surveillance-and-measurement-alliance-prisma-pakistan
#28
JOURNAL ARTICLE
Sabahat Naz, Ali Jaffar, Nida Yazdani, Muhammad Kashif, Zaid Hussain, Uzma Khan, Fouzia Farooq, Muhammad Imran Nisar, Fyezah Jehan, Emily Smith, Zahra Hoodbhoy
PURPOSE: Pakistan has disproportionately high maternal and neonatal morbidity and mortality. There is a lack of detailed, population-representative data to provide evidence for risk factors, morbidities and mortality among pregnant women and their newborns. The Pregnancy Risk, Infant Surveillance and Measurement Alliance (PRISMA) is a multicountry open cohort that aims to collect high-dimensional, standardised data across five South Asian and African countries for estimating risk and developing innovative strategies to optimise pregnancy outcomes for mothers and their newborns...
December 10, 2023: BMJ Open
https://read.qxmd.com/read/38057580/postnatal-acetaminophen-exposure-and-neurodevelopmental-outcomes-at-18-21-months-corrected-gestational-age-in-preterm-infants-29-weeks-gestation-a-retrospective-cohort-study
#29
JOURNAL ARTICLE
Amelia Srajer, Smita Roychoudhury, Selphee Tang, Shabih U Hasan, Sarfaraz Momin, Leonora Hendson, Belal Alshaikh, Kamran Yusuf
BACKGROUND: Studies have reported prenatal acetaminophen exposure is associated with abnormal neurodevelopment. There is limited and conflicting data on neurodevelopmental outcomes following postnatal acetaminophen exposure. Our objective was to investigate the neurodevelopmental outcomes of preterm infants < 29 weeks gestation postnatally exposed to acetaminophen. METHODS: Retrospective cohort study of infants born between 2008 and 2017 at a tertiary care perinatal center...
December 7, 2023: Pediatric Research
https://read.qxmd.com/read/38026389/perinatal-tuberculosis-an-approach-to-an-under-recognized-diagnosis
#30
REVIEW
H Simon Schaaf, Adrie Bekker, Helena Rabie
Tuberculosis (TB) in young infants (<3 months of age), often referred to as perinatal TB, is underdiagnosed, leading to severe morbidity and high mortality. Perinatal TB includes both congenital and postnatal transmission of Mycobacterium tuberculosis . We aimed to increase an awareness of TB in neonates and young infants and to provide guidance on the assessment and management when in contact with mothers with TB during or soon after pregnancy. Approximately 217,000 pregnant women develop TB annually; if they are not diagnosed and treated during pregnancy, their infants are at high risk of adverse birth outcomes and TB disease...
2023: Frontiers in Public Health
https://read.qxmd.com/read/38026062/universal-screening-for-sars-cov-2-in-obstetric-care-clinical-characteristics-and-maternofetal-outcomes-in-a-latin-american-high-complexity-unit
#31
JOURNAL ARTICLE
María Fernanda Escobar Vidarte, Maria Paula Echavarria, Javier Andrés Carvajal, Ludwig Luis Albornoz, Evelyn E Peña-Zarate, Laura Libreros, Daniela Nasner, Juan Diego Vélez
The asymptomatic population's role in COVID-19 transmission poses challenges for control efforts. Pregnant women are susceptible to severe manifestations, increasing maternal and perinatal morbidity and mortality. This study describes the clinical characteristics, maternal and fetal outcomes, and our experience in universal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) screening of pregnant women admitted to a high-complexity obstetric unit in Latin America. Of 568 pregnant women tested for SARS-CoV-2, 23 obtained a positive result...
2023: Journal of Patient Experience
https://read.qxmd.com/read/38002589/group-a-streptococcus-infection-in-neonatal-population-a-systematic-review-of-the-literature
#32
REVIEW
Rozeta Sokou, Filippos Filippatos, Vasiliki Daniil, Efstathia-Danai Bikouli, Andreas G Tsantes, Daniele Piovani, Stefanos Bonovas, Zoi Iliodromiti, Theodora Boutsikou, Argirios E Tsantes, Nicoletta Iacovidou, Aikaterini Konstantinidi
(1) Background: The importance of group A streptococcus (GAS) infection severity has been recognized in children and adults. However, to our knowledge, there have been no systematic reviews or pooled assessments of the incidence and outcome of invasive GAS (iGAS) disease in neonates, a potentially high-risk population. Therefore, we performed a systematic review of available data regarding the risk factors, clinical presentation, and outcome of GAS infection in neonates. (2) Methods: An electronic search of the existing literature was carried out during the period July 2023-September 2023 in the PubMed and Scopus databases, considering studies referring to GAS infection in the neonatal population...
November 8, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37927663/role-of-lactate-dehydrogenase-and-lymphocyte-count-as-predictors-of-poor-perinatal-outcomes-in-covid-19-infected-pregnancies-requiring-hospitalization-and-delivery-a-retrospective-cohort-study
#33
JOURNAL ARTICLE
Sebnem Alanya Tosun, Kivanc Celikkalkan, Alptekin Tosun, Azime Bulut, Enis Ozkaya, Ilknur Senel, Muhammet Bulut, Gokhan Ordu
INTRODUCTION: Physiological, hormonal, or biochemical changes may be related to the increased morbidity of COVID-19 during pregnancy. Our knowledge remains limited about which pregnant women will worsen and develop complications. The aim was to evaluate the maternal, fetal, and neonatal outcomes in hospitalized pregnant women who delivered while infected with acute COVID-19 and to investigate the possible predictors of poor prognosis in a tertiary pandemic center. METHODS: A retrospective cohort study was conducted on pregnant women who required termination or delivery during a COVID-19 infection in a tertiary hospital...
October 2023: Curēus
https://read.qxmd.com/read/37927616/effects-of-covid-19-infection-on-the-oral-glucose-tolerance-test-results-in-pregnancy
#34
JOURNAL ARTICLE
Cevat Rifat Cundubey, Mehmet Ak, Bertan Demir, Seyma Cam
INTRODUCTION: The aim of this study was to evaluate the results of a 75 g oral glucose tolerance test (OGTT) performed in the second trimester of pregnancy, the prevalence of gestational diabetes mellitus (GDM), and perinatal outcomes in pregnant women with a history of coronavirus disease 2019 (COVID-19) infection and to examine the effect of COVID-19 infection history on OGTT results and GDM prevalence. METHODS: We retrospectively analyzed the data of 463 patients who visited the Gynecology and Obstetrics Department of Kayseri City Hospital between March 2020 and January 2023 and were administered a 75-g OGTT in the second trimester of their pregnancy...
October 2023: Curēus
https://read.qxmd.com/read/37927397/clinical-characteristics-treatment-outcome-and-associated-factors-of-epilepsy-among-children-at-hospitals-of-north-west-ethiopia
#35
JOURNAL ARTICLE
Mohammed Nasir, Ermias Abebaw, Muluken Ahmed, Daniel Bekele Ketema
BACKGROUND: Epilepsy is an important cause of neurological morbidity in children and adolescents. Clinical parameters are the main diagnostic tools, especially in developing countries. Although cost-effective treatments for epilepsy are available, studies have shown that uncontrolled seizures can occur in many patients. OBJECTIVE: To assess clinical characteristics, treatment outcomes, and associated factors for controlled epilepsy among children with epilepsy who underwent follow-up at the Debre Markos Comprehensive Specialized Hospital, North-west Ethiopia from October 28, 2020, to April 28, 2021...
2023: Pediatric Health, Medicine and Therapeutics
https://read.qxmd.com/read/37918833/covid-19-pregnancy-and-diabetes-mellitus
#36
JOURNAL ARTICLE
Helmut J Kleinwechter, Katharina S Weber, Tatjana P Liedtke, Ute Schäfer-Graf, Tanja Groten, Mario Rüdiger, Ulrich Pecks
During the severe acute respiratory distress virus coronavirus type 2 (SARS-CoV-2) pandemic, many women were infected during their pregnancies. The SARS-CoV-2-induced coronavirus disease 19 (COVID-19) has an impact on maternal health and pregnancy outcomes; peripartum and perinatal morbidity and mortality are increased. Pregnancy is considered a risk factor for severe COVID-19 course. Additional risk factors during pregnancy are diabetes mellitus, gestational diabetes mellitus (GDM), and obesity. Systemic inflammation can lead to severe metabolic dysregulation with ketoacidosis...
November 2, 2023: Zeitschrift Für Geburtshilfe und Neonatologie
https://read.qxmd.com/read/37909232/neurodevelopment-among-children-exposed-to-hiv-and-uninfected-in-sub-saharan-africa
#37
JOURNAL ARTICLE
Michelle A Bulterys, Irene Njuguna, Mary Mahy, Laurie A Gulaid, Katheen M Powis, Catherine J Wedderburn, Grace John-Stewart
INTRODUCTION: The population of 16 million children exposed to HIV and uninfected (CHEU) under 15 years of age continues to expand rapidly, and the estimated prevalence of CHEU exceeds 20% in several countries in sub-Saharan Africa with high HIV prevalence. Some evidence suggests that CHEU experience suboptimal neurodevelopmental outcomes compared to children born to women without HIV. In this commentary, we discuss the latest research on biologic and socio-behavioural factors associated with neurodevelopmental outcomes among CHEU...
October 2023: Journal of the International AIDS Society
https://read.qxmd.com/read/37909219/strengthening-the-evidence-to-improve-health-outcomes-of-children-with-perinatal-hiv-exposure
#38
JOURNAL ARTICLE
Sonia Lee, Susannah Allison, Pim Brouwers
INTRODUCTION: The number of children exposed to HIV and possibly to antiretroviral therapy (ART) in utero and during breastfeeding and are uninfected (HEU) globally will continue to increase from the estimated 15.9 million in 2021. DISCUSSION: There are still significant gaps in our understanding of the impact of HIV and/or ART exposure in children who are HEU, in terms of prevalence/incidence and severity on health and wellbeing, and long after exposure has ended...
October 2023: Journal of the International AIDS Society
https://read.qxmd.com/read/37879386/development-of-a-prediction-model-of-postpartum-hospital-use-using-an-equity-focused-approach
#39
JOURNAL ARTICLE
Teresa Janevic, Lewis E Tomalin, Kimberly B Glazer, Natalie Boychuk, Adina Kern-Goldberger, Micki Burdick, Frances Howell, Mayte Suarez-Farinas, Natalia Egorova, Jennifer Zeitlin, Paul Hebert, Elizabeth A Howell
BACKGROUND: Racial inequities in maternal morbidity and mortality persist into the postpartum period, leading to a higher rate of postpartum hospital use among Black and Hispanic people. Delivery hospitalizations provide an opportunity to screen and identify people at high risk to prevent adverse postpartum outcomes. Current models do not adequately incorporate social and structural determinants of health, and some include race, which may result in biased risk stratification. OBJECTIVE: This study aimed to develop a risk prediction model of postpartum hospital use while incorporating social and structural determinants of health and using an equity approach...
October 23, 2023: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/37824725/the-neural-and-cardiovascular-effects-of-exposure-of-gram-positive-bacterial-inflammation-in-preterm-fetal-sheep
#40
JOURNAL ARTICLE
Simerdeep K Dhillon, Christopher A Lear, Joanne O Davidson, Shoichi Magawa, Alistair J Gunn, Laura Bennet
Perinatal infection or inflammation are associated with adverse neurodevelopmental effects and cardiovascular impairments in preterm infants. Most preclinical studies have examined the effects of gram-negative bacterial inflammation on the developing brain, although gram-positive bacterial infections are a major contributor to adverse outcomes. Killed Su-strain group 3 A streptococcus pyogenes (Picibanil, OK-432) is being used for pleurodesis in fetal hydrothorax/chylothorax. We therefore examined the neural and cardiovascular effects of clinically relevant intra-plural infusions of Picibanil...
October 12, 2023: Journal of Cerebral Blood Flow and Metabolism
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