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https://www.readbyqxmd.com/read/27834480/a-caucasian-jk-a-jk-b-woman-with-jk-a-b-red-blood-cells-anti-jkb-and-a-novel-jk-b-allele-c-1038delg
#1
Glenn Ramsey, Ricardo D Sumugod, Paul F Lindholm, Jules G Zinni, Jessica A Keller, Trina Horn, Margaret A Keller
No abstract text is available yet for this article.
September 2016: Immunohematology
https://www.readbyqxmd.com/read/27720088/association-between-factor-v-leiden-mutation-small-for-gestational-age-and-preterm-birth-a-systematic-review-and-meta-analysis
#2
Erin M Hemsworth, Amanda M O'Reilly, Victoria M Allen, Stefan Kuhle, Jo-Ann K Brock
OBJECTIVE: To estimate the association of a maternal factor V Leiden (FVL) mutation with SGA and preterm birth. DATA SOURCES: We performed a search of PubMed, Embase, Scopus, CINAHL, and the Cochrane Library from inception to April 2016 for cohort and case-control studies of women with FVL mutation and associated outcomes of SGA and preterm birth that included a reference group without FVL mutation. Additional studies were identified from reference lists of relevant research and review articles...
October 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/27385728/id2-mediates-the-transforming-growth-factor-%C3%AE-1-induced-warburg-like-effect-seen-in-the-peritoneum-of-women-with-endometriosis
#3
Vicky J Young, Syed F Ahmad, Jeremy K Brown, W Colin Duncan, Andrew W Horne
STUDY QUESTION: Is inhibitor of DNA-binding protein 2 (ID2) a mediator of the transforming growth factor (TGF)-β1-induced Warburg-like effect seen in the peritoneum of women with endometriosis? SUMMARY ANSWER: The TGF-β1-induced changes in the metabolic phenotype of peritoneal mesothelial cells from women with endometriosis are mediated through the ID2 pathway. WHAT IS KNOWN ALREADY: TGF-β1 induces the metabolic conversion of glucose to lactate via aerobic glycolysis (the 'Warburg effect') in the peritoneum of women with endometriosis, through increased expression of the transcription factor hypoxia inducible factor α (HIF-1α)...
September 2016: Molecular Human Reproduction
https://www.readbyqxmd.com/read/27267757/sub-saharan-red-cell-antigen-phenotypes-and-glucose-6-phosphate-dehydrogenase-deficiency-variants-in-french-guiana
#4
Florence Petit, Pascal Bailly, Jacques Chiaroni, Stéphane Mazières
BACKGROUND: The treatment of Plasmodium vivax infections requires the use of primaquine, which can lead to severe haemolysis in glucose-6-phosphate dehydrogenase (G6PD)-deficient individuals. However, most of the Latin American countries, which are still endemic for vivax malaria, lack information on the distribution of G6PD deficiency (G6PDd). No survey has been performed so far in French Guiana. Herein, 80 individuals of the French Guianan Noir Marron population were scrutinized for red cell surface antigens of six blood group systems (ABO, Rh, Kell, Kidd, Duffy and MNS) and G6PD genetic polymorphisms...
2016: Malaria Journal
https://www.readbyqxmd.com/read/26866167/risk-of-red-blood-cell-alloimmunisation-in-rwanda-assessment-of-pretransfusion-crossmatch-techniques-used-in-district-hospitals
#5
E Ndahimana, A Gothot, C Gérard, F Senyana, S R'Zik, O Mukabayire, L Mutesa
BACKGROUND: Screening of alloantibodies in patients is not yet done in district hospitals of Rwanda. The practice is to transfuse ABO/D compatible blood following an immediate spin crossmatch (IS-XM) or indirect antiglobulin test crossmatch (IAT-XM). OBJECTIVES: To assess the risk of red blood cell (RBC) alloimmunisation associated with the use of IS-XM compared to the IAT-XM in patients receiving blood transfusions in district hospitals in Rwanda. DESIGN: A cross-sectional comparative descriptive study...
April 2013: East African Medical Journal
https://www.readbyqxmd.com/read/26866096/risk-of-red-blood-cell-alloimmunisation-in-rwanda-assessment-of-pretransfusion-crossmatch-techniques-used-in-district-hospitals
#6
E Ndahimana, A Gothot, C Gérard, F Senyana, S R'Zik, O Mukabayire, L Mutesa
BACKGROUND: Screening of alloantibodies in patients is not yet done in district hospitals of Rwanda. The practice is to transfuse ABO/D compatible blood following an immediate spin crossmatch (IS-XM) or indirect antiglobulin test crossmatch (IAT-XM). OBJECTIVES: To assess the risk of red blood cell (RBC) alloimmunisation associated with the use of IS-XM compared to the IAT-XM in patients receiving blood transfusions in district hospitals in Rwanda. DESIGN: A cross-sectional comparative descriptive study...
April 2013: East African Medical Journal
https://www.readbyqxmd.com/read/26605447/alloimmune-red-blood-cell-antibodies-prevalence-and-pathogenicity-in-a-canadian-prenatal-population
#7
Rhonda Zwingerman, Venu Jain, Judith Hannon, Nora Zwingerman, Gwen Clarke
OBJECTIVE: The goals of this study were to determine the prevalence and relative frequencies of red blood cell antibodies in a Canadian prenatal population, and to evaluate the fetal and neonatal outcomes of affected pregnancies. METHODS: We conducted a retrospective review of pregnancies that screened positive for red cell antibodies between 2006 and 2010. The following antibodies were included: anti-D, -C, -c, -E, -e, -Fya, -Fyb, -Jka, and-Jkb. Cases of anti-Kell as the sole antibody were excluded...
September 2015: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/26363547/autologous-infant-and-allogeneic-adult-red-cells-demonstrate-similar-concurrent-post-transfusion-survival-in-very-low-birth-weight-neonates
#8
John A Widness, Denison J Kuruvilla, Donald M Mock, Nell I Matthews, Demet Nalbant, Gretchen A Cress, Robert L Schmidt, Ronald G Strauss, M Bridget Zimmerman, Peter Veng-Pedersen
OBJECTIVE: Based on the hypothesis that neonatal autologous red blood cell (RBC) survival (RCS) is substantially shorter than adult RBC, we concurrently tracked the survival of transfused biotin-labeled autologous neonatal and allogeneic adult RBC into ventilated, very low birth weight infants. STUDY DESIGN: RBC aliquots from the first clinically ordered, allogeneic adult RBC transfusion and from autologous infant blood were labeled at separate biotin densities (biotin-labeled RBC [BioRBC]) and transfused...
November 2015: Journal of Pediatrics
https://www.readbyqxmd.com/read/25637293/importance-of-direct-antiglobulin-test-dat-in-cord-blood-causes-of-dat-in-a-cohort-study
#9
Serena Valsami, Marianna Politou, Τheodora Boutsikou, Despina Briana, Milena Papatesta, Ariadne Malamitsi-Puchner
BACKGROUND: The direct antiglobulin test (DAT) is the cornerstone of the diagnosis of hemolytic disease of the newborn (HDN). The aim of this study was to review the incidence and causes of positive DAT in cord blood in relation to development of HDN. METHODS: We retrospectively reviewed all results of DAT, which is routinely performed in cord blood samples, along with the laboratory and infants' medical records. RESULTS: DAT was positive in 70/2695 (2...
August 2015: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/25312103/kidd-blood-group-phenotypes-among-pregnant-women-in-sokoto-north-western-nigeria
#10
Osaro Erhabor, Mairo Hassan, Yusuf Bashir Alhaji, Ahmed Yakubu, Hauwa Buhari
OBJECTIVE: To investigate the prevalence of Kidd antigens among pregnant women in Sokoto, North Western Nigeria. METHODS: One hundred and sixty two pregnant women aged 18-45 years [mean age (27.19±4.72) years] attending antenatal clinic in Usmanu Danfodiyo University Teaching Hospital, Sokoto, were screened for the presence of Kidd blood group antigens using the conventional tube method and anti-Jka and Jkb reagents (Lorne Laboratories, UK). RESULTS: Out of the 162 pregnant women tested, 82 (50...
September 2014: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/24877238/jk-null-alleles-identified-from-japanese-individuals-with-jk-a%C3%A2-b%C3%A2-phenotype
#11
T Onodera, K Sasaki, H Tsuneyama, K Isa, K Ogasawara, M Satake, K Tadokoro, M Uchikawa
The Kidd blood group system consists of three common phenotypes: Jk(a+b−), Jk(a−b+) and Jk(a+b+), and one rare phenotype, Jk(a−b−). Jka/Jkb polymorphism is associated with c.838G>A (p.Asp280Asn) in exon 9 of the JK (SLC14A1) gene, and the corresponding alleles are named JK*01 and JK*02. The rare phenotype Jk(a−b−) was first found in a Filipina of Spanish and Chinese ancestry, and to date, several JK null alleles responsible for the Jk(a−b−) phenotype have been reported. We report seven novel JK null alleles, 4 with a JK*01 background and 3 with a JK*02 background, identified from Jk(a−b−) Japanese...
May 2014: Vox Sanguinis
https://www.readbyqxmd.com/read/24839583/dna-binding-polyamides-and-the-importance-of-dna-recognition-in-their-use-as-gene-specific-and-antiviral-agents
#12
Kevin J Koeller, G Davis Harris, Karl Aston, Gaofei He, Carlos H Castaneda, Melissa A Thornton, Terri G Edwards, Shuo Wang, Rupesh Nanjunda, W David Wilson, Chris Fisher, James K Bashkin
There is a long history for the bioorganic and biomedical use of N-methyl-pyrrole-derived polyamides (PAs) that are higher homologs of natural products such as distamycin A and netropsin. This work has been pursued by many groups, with the Dervan and Sugiyama groups responsible for many breakthroughs. We have studied PAs since about 1999, partly in industry and partly in academia. Early in this program, we reported methods to control cellular uptake of polyamides in cancer cell lines and other cells likely to have multidrug resistance efflux pumps induced...
February 20, 2014: Medicinal Chemistry
https://www.readbyqxmd.com/read/24839369/hemolytic-disease-of-the-newborn-due-to-anti-jkb-case-report-and-review-of-the-literature
#13
Diego Velasco Rodríguez, G Pérez-Segura, A Jiménez-Ubieto, M A Rodríguez, L Montejano
Although anti-Jkb is a well-defined cause of severe acute or delayed hemolytic transfusion reactions, it is rarely associated with severe Hemolytic Disease of the Newborn (HDN), even with high antibody titer. To date, only 13 cases have been reported, so the possible reasons for that still remain unclear. Most of HDN due to anti-Jkb are mild-to-moderate, and usually have a good prognosis. A 41-years-old woman, who had a positive antibody screening test in her 13th week of pregnancy, was sent to the blood bank for study before an amniocentesis...
June 2014: Indian Journal of Hematology & Blood Transfusion
https://www.readbyqxmd.com/read/24689681/prevalence-of-clinically-significant-red-blood-cell-alloantibodies-in-pregnant-women-at-a-large-tertiary-care-facility
#14
Heather M Smith, Rosetta S Shirey, Sandra K Thoman, Jay B Jackson
More than 50 red blood cell (RBC) alloantibodies are known to cause hemolytic disease of the fetus and newborn (HDFN).Although Rh immune globulin (RhiG) prophylaxis has significantly reduced the incidence of pregnancies complicated by anti-D, the need to detect and monitor maternal allo antibodies capable of causing HDFN is still a concern. The prevalence and specificity of these alloantibodies were determined. In this retrospective study, the prevalence and specificities of unexpected RBC alloantibodies known to cause HDFN in pregnant women at a tertiary-care facility during a 5-year period were compiled and analyzed...
2013: Immunohematology
https://www.readbyqxmd.com/read/23826966/alloimmunisation-during-pregnancy-in-greece-need-for-nationwide-hdfn-prevention-programme
#15
MULTICENTER STUDY
L Foudoulaki-Paparizos, S Valsami, N Bournas, A Tsantes, P Grapsas, G Mantzios, A Travlou, M Politou
AIM/OBJECTIVES: To access the incidence and specificity of maternal red blood cells alloimmunisation and its relevant clinical impact in Greece. BACKGROUND: The rate of alloimmunisation in pregnant women in Greece is unknown. MATERIALS/METHODS: We performed a 4-year study in two tertiary hospitals in Greece. Demographics, transfusion and obstetric history were analysed. Maternal alloimmunisation was detected with indirect anti-globulin test...
August 2013: Transfusion Medicine
https://www.readbyqxmd.com/read/22937494/impact-of-timing-to-coronary-angiography-in-acute-coronary-syndrome-on-contemporary-clinical-practice
#16
Angela S Koh, Stanley Chia, Tan Jkb, Siti M Zaini, Guo Kwq, Yeo Kk, Chua Tsj, Tian Hai Koh, Jack W C Tan
Recent studies appear to suggest a correlation between timing to coronary angiography and clinical outcome among patients with acute coronary syndrome (ACS). We aim to study 12-month outcomes of ACS patients who are stratified according to early (≤24 hours), intermediate (>24 to <48 hours) and delayed (≥48 hours) coronary angiography. This is a prospective observational study of patients with ACS defined as either unstable angina pectoris or non-ST elevation myocardial infarction (MI) admitted between October 2008 and July 2009...
2012: American Journal of Cardiovascular Disease
https://www.readbyqxmd.com/read/22858444/is-there-any-relationship-between-expressions-of-minor-blood-group-antigens-with-htlv-i-infection
#17
Mohammad Hadi Sadeghian, Mohammad Reza Keramati, Hossein Ayatollahi, Atefeh Shirinzadeh Feizabadi, Farahnaz Tehranaian, Hossein Shakibyee
BACKGROUND: The frequency of Human T lymphotropic Virus-1 (HTLV 1) is 2-3% in the general population and 0.7% in blood donors in northeast Iran. It is very important that we recognize the contributing factors in the pathogenesis of this virus. There are many reports that show that susceptibility to some infections is closely linked to the expression of certain blood group antigens. This study was performed to evaluate any association between minor blood group antigens and HTLV-I infection in northeast Iran...
October 2012: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/21291870/opioid-like-compound-exerts-anti-fibrotic-activity-via-decreased-hepatic-stellate-cell-activation-and-inflammation
#18
Stephani A Day, Ashley M Lakner, Cathy C Moore, Mao-Hsiung Yen, Mark G Clemens, Edwin S Wu, Laura W Schrum
Hepatic fibrosis is characterized by excess type I collagen deposition and exacerbated inflammatory response. Naltrexone, an opioid receptor antagonist used for treating alcohol abuse, attenuates hepatocellular injury in fibrotic animal models, which can be accompanied by deleterious side effects. Additionally, opioid neurotransmission is upregulated in patients with inflammatory liver disease. Several derivatives of Naltrexone, Nalmefene (Nal) and JKB-119, exert immunomodulatory activity; however, unlike Nal, JKB-119 does not show significant opioid receptor antagonism...
April 15, 2011: Biochemical Pharmacology
https://www.readbyqxmd.com/read/18705240/the-role-of-the-direct-antiglobulin-test-in-pre-transfusion-investigations-and-the-approach-to-selecting-blood-for-transfusion-in-autoimmune-haemolytic-anaemia-results-of-a-regional-survey
#19
Giancarlo Maria Liumbruno, Adriana Tognaccini, Rosaria Bonini, Giuseppe Curciarello, Isio Masini, Alvaro Ringressi, Francesco Tornabene, Renato Vanacore
INTRODUCTION: The aim of this study was to conduct a Regional survey to determine the policies and ways of performing the direct antiglobulin test in pre-transfusion screening, the approach used in cases giving positive results with this test and the technical and operative modalities for choosing blood for transfusion in cases of autoimmune haemolytic anaemia. MATERIALS AND METHODS: A questionnaire, containing ten multiple-choice questions, was sent to all the transfusion centres in the Region of Tuscany...
July 2008: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/18664282/candida-tropicalis-spondylodiskitis-in-a-patient-with-carcinoma-of-sigmoid-colon-a-case-report
#20
Chandra Jkb Parthiban, Shiju A Majeed, Shanthanam S Mahalingam
ABSTRACT: Fungal spondylodiskitis is being increasingly reported in immunocompromised patients. A patient who presented with severe back pain three months following laparoscopic resection of Carcinoma of Sigmoid colon is presented here. Magnetic Resonance Imaging of the spine showed evidence of multilevel lumbar spondylodiskitis. Biopsy done via the posterior approach showed Candida tropicalis sensitive to fluconazole and resistant to Amphotericin B. Patient was treated with fluconazole and had good relief...
2008: Cases Journal
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