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Francisco-J Renero-C
Background: One of the complications of the diabetes mellitus is the amputation of the lower limbs. This complication may be developed after an insidious ulcer, that may be raised by the peripheral neuropathy or the ischaemic limb, and that the ulcer get infected. That is, to develop an ulcer, in the diabetic patient, three factors should be taken into the account, the autonomic nervous system, the blood supply and the inmune system. Methods: In this work, the thermogram is used to identify regions on the plantar skin with blood supply deficiencies and the behaviour of the thermoregulation process...
2018: Diabetic Foot & Ankle
J Benitez-Del-Castillo Sánchez, M D Morillo-Rojas, C Galbis-Estrada, M D Pinazo-Duran
OBJECTIVE: To determine the expression profile of immune response and inflammation (IRI) mediator molecules in tears from patients with dry eye (DE), and those suspected of having or have primary open-angle glaucoma (POAG) under treatment and compare them with healthy controls. METHODS: A prospective observational cohort study including 107 participants sub-divided into: healthy controls (CG; n=30), patients with DE (DEG; n=41) and patients suspected of having or have POAG and on hypotensive treatment (POAG-G; n=36)...
May 2017: Archivos de la Sociedad Española de Oftalmología
Lorena Martín-Jaular, Armando de Menezes-Neto, Marta Monguió-Tortajada, Aleix Elizalde-Torrent, Míriam Díaz-Varela, Carmen Fernández-Becerra, Francesc E Borras, Maria Montoya, Hernando A Del Portillo
Reticulocyte-derived exosomes (rex) are 30-100 nm membrane vesicles of endocytic origin released during the maturation of reticulocytes to erythrocytes upon fusion of multivesicular bodies with the plasma membrane. Combination of CpG-ODN with rex obtained from BALB/c mice infected with the reticulocyte-prone non-lethal P. yoelii 17X malaria strain (rexPy), had been shown to induce survival and long lasting protection. Here, we show that splenectomized mice are not protected upon rexPy+CpG inmunizations and that protection is restored upon passive transfer of splenocytes obtained from animals immunized with rexPy+CpG...
2016: Frontiers in Cell and Developmental Biology
Ana M López-Sobaler, Aránzazu Aparicio Vizuete, Rosa María Ortega Anta
Both the Green® kiwifruit (Actinidia deliciosa)and the Sungold® one (A. chinensis)stand out among other commonly consumed fruits for their nutritional composition. They are fruits exceptionally rich in vitamin C, since green kiwi fruit have twice and Sungold® have three times the same amount of the vitamin of strawberries or oranges. Kiwifruit is very rich in vitamins E, K, folates, carotenoids, potassium, fiber and other phytochemicals. Regular consumption of kiwifruit, in the context of a balanced diet, has proven to have beneficial effects on immune function and antioxidant defense; also in the gastrointestinal function, improving protein digestion and constipation; and in the upper respiratory tract, preventing infections and improving their symptoms...
July 12, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Bingsong Wang, Yijun Li, Xiaolu Wu, Qingqing Liu, Xue Tang, Zuo Wang
Objetivos: oligoelementos como zinc (Zn), hierro (Fe) y cobre (Cu) tienen una influencia significativa en el mantenimiento de la función inmune y del metabolismo normales; modulan la función immune e influyen en la susceptibilidad del organismo ante infecciones. Pero la relación entre trazas de estos elementos y la bronconeumonía resultó incierta. Métodos: en este estudio fueron incluidos 28 niños con bronconeumonía y 46 niños sanos agrupados por edad. Se determinaron los niveles de Zn, Cu, Fe, calcio (Ca) y/o magnesio (Mg) en el suero de los niños con bronconeumonía y sin ella mediante espectrofotometría de absorción atómica...
March 25, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
M Carolina Rivacoba, José Cofré, M Elena Santolaya
Invasive pneumococcal disease (IPD) remains as an important cause of morbidity in the world and in our country, while in Chile the incidence has decreased after the incorporation of the 10 valent pneumococcal conjugate vaccine, in the routine infant inmunization schedule (EPI). One of the expected effects of the program after vaccination with 10-valent pneumococcal vaccine is the likely replacement serotype phenomenon that means the presence of ENI caused by serotypes not included in the vaccine. In this context, we present the case of a child with pneumococcal meningitis caused by serotype 19 A of fatal course...
February 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
Anju Seth, Sudha Deepa, Renu Dutta, Jagdish Chandra
BACKGROUND: Children with HIV (CLHIV) respond poorly to primary immunization with measles vaccine and those responding tend to lose protective titer of antibodies by 2-3 years old. Revaccinating CLHIV after immune reconstitution with antiretroviral therapy (ART) may result in good seroconversion, thereby conferring them protection from measles. The objective was to study prevalence of measles antibodies in CLHIV receiving ART before and after immunization with MMR vaccine. METHODS: CLHIV in the age 5-18 years receiving ART for >6 months and with CD 4 count >15% were included in this prospective study...
January 2016: Pediatric Infectious Disease Journal
Belén Zapatera, Andreu Prados, Sonia Gómez-Martínez, Ascensión Marcos
Immunonutrition is an emergent and interdisciplinary subject, since it comprises several aspects related to Nutrition, Immunity, Infection, Inflammation, and Injury or tissue damage, what is known as Nutrition and 4 “Is”. Within these interactions the endocrine, nervous and immune systems are involved, microbiota being a part of the last one. Nowadays, gut microbiota has been shown to play an essential role, not only in the gastrointestinal tract but also into the nervous system, because of its bilateral connection...
February 26, 2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Lilian María Mederos Cuervo, Angélica Reyes Pérez, Lidunka Valdes Alonso, Francisco Rodríguez Delgado, Misleydis Sardiñas Aragón, María Rosarys Martínez Romero, Raúl Díaz Romero
A case is presented of coinfection with Mycobacterium malmoense and Mycobacterium tuberculosis in a Cuban patient with AIDS which produced respiratory and liver disease respectively. Cultures done from sputum samples showed the presence of a non-pigmented, slow growing mycobacterial strain belonging to Runyon group III and identified as Mycobacterium malmoense. From cultures of liver tissue removed laparoscopically, a strain was isolated and subsequently identified as Mycobacterium tuberculosis. Anatomapathologic examination confirmed the diagnosis of tuberculosis, the patient received specific treatment and had a favorable clinical course...
October 2014: Revista Peruana de Medicina Experimental y Salud Pública
Edward Mezones-Holguín, Rafael Bolaños-Díaz, Víctor Fiestas, César Sanabria, Alfonso Gutiérrez-Aguado, Fabián Fiestas, Víctor J Suárez, Alfonso J Rodriguez-Morales, Adrián V Hernández
INTRODUCTION: Pneumococcal pneumonia (PP) has a high burden of morbimortality in children. Use of pneumococcal conjugate vaccines (PCVs) is an effective preventive measure. After PCV 7-valent (PCV7) withdrawal, PCV 10-valent (PCV10) and PCV 13-valent (PCV13) are the alternatives in Peru. This study aimed to evaluate cost effectiveness of these vaccines in preventing PP in Peruvian children <5 years-old. METHODOLOGY: A cost-effectiveness analysis was developed in three phases: a systematic evidence search for calculating effectiveness; a cost analysis for vaccine strategies and outcome management; and an economic model based on decision tree analysis, including deterministic and probabilistic sensitivity analysis using acceptability curves, tornado diagram, and Monte Carlo simulation...
December 15, 2014: Journal of Infection in Developing Countries
Carlos Grande García, Rafael Martínez Martínez, David Valcarcel Ferreiras
No abstract text is available yet for this article.
November 7, 2014: Medicina Clínica
Cecília Maria Passos Vázquez, Raquel Simões Mendes Netto, Kiriaque Barra Ferreira Barbosa, Tatiana Rodrigues de Moura, Roque Pacheco de Almeida, Malcolm S Duthie, Amelia Ribeiro de Jesus
Leprosy is a chronic infectious disease caused by Mycobacterium leprae, an intracellular bacillus of airborne transmission. The disease affects the skin and peripheral nerves and can cause neurological sequelae. The bacillus multiplies slowly in the host and the disease probably occurs due to malfunctioning in host immune response. This review addresses the role of some specific micronutrients in the immune response, such as Vitamins A, D, E, C, Zinc and Selenium, detailing their mechanisms of actions in infectious diseases, and in leprosy...
January 1, 2014: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
P Casas Rodera, D A de Luis, C Gómez Candela, J M Culebras
INTRODUCTION: Significant malnutrition exists in a high percentage of patients with head and neck cancer. Malnutrition is associated with defects in immune function that may impair the host response to malignancy. Malnutrition and immunosupression make patients highly susceptible to postoperative infections and complications. OBJECTIVES: Some studies of patients receiving immuno-nutrition in the perioperative period in head and neck cancer have shown beneficial effects on clinical outcome and inmune status...
May 2012: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Miguel A Zambrano-Velarde, Daniel de la O-Peña, Quetzalcóatl Chávez-Peña, Martín Bedolla-Barajas
BACKGROUND: immune thrombocytopenic purpura is characterized by bleeding disorders associated with decreased platelet count secondary to antiplatelet autoantibodies. The aim of this study was to evaluate the utility of rituximab in the management of refractory immune thrombocytopenic purpura. CLINICAL CASES: four women with immune thrombocytopenic purpura unresponsiveness to standard therapy were evaluated in relation to clinical response and total platelets counts at different time intervals after rituximab administration...
March 2012: Revista Médica del Instituto Mexicano del Seguro Social
María Consuelo Calomarde Rees, Carlos Iglesias Sánchez, Elena Martín Boado, Gabriel Vegas, Félix Omeñaca, Antonio González González
Perinatal hemolytic disease occurs secondary to a hemolytic phenomenon of immune origin resulting in fetal or neonatal anemia. A 38-year-old pregnant woman was referred to the Department of high risk Obstetrics, Hospital Universitario La Paz Madrid because of presenting a dichorionic diamniotic twin pregnancy spontaneously, pre-pregnancy diabetes poorly controlled and severe alloinmunization anti-D. Her first pregnancy ended in a normal delivery at term; in the period of 4 years, she has three newborn with 36, 34 and 40 weeks respectively, who die with a week of life...
March 2012: Ginecología y Obstetricia de México
J A Petan, N Undre, M R First, K Saito, T Ohara, O Iwabe, H Mimura, M Suzuki, S Kitamura
Tacrolimus is an important immunosuppressive agent used to prevent allograft rejection after transplantation. Tacrolimus has a narrow therapeutic index; therefore, it is essential that the physicochemical properties of generic formulations be identical to the brand-name formulation, Prograf. In this study, the physicochemical properties of generic tacrolimus formulations were compared with Prograf. The drug dissolution profiles of generic formulations of tacrolimus were different from that of Prograf. Tacrobell and T-Inmun exhibited faster dissolution than Prograf, and Tenacrine, Framebin, and Talgraf showed slower and incomplete drug dissolution, releasing 24% to 51% of tacrolimus within 2 hours...
June 2008: Transplantation Proceedings
V U Vaughan
No abstract text is available yet for this article.
October 27, 1893: Science
Gerardo A Belletti, Verónica Savio, Daniel Minoldo, Susana Caminos, Marcelo A Yorio
A 66 years female, who was since last year under astenia, arthralgias, pimply lesions in spread plates and tests showing eritrosedimentation over 100 mm, anemi, leucocitosis with neutrofilia, policlonal hypergammaglobulinemia, slight proteinuria and IgE on 900. This patient was sporadically treated with corticoids. When made the medical consult had lost 34lb., was under anorexy, as well as dyspepsia. Hemoglobyn 6.9 gr/dl, leucocytes 20000/mm3, neutrofils at 90%, proteinogram the same as former, with hypoalbuminemia...
2004: Revista de la Facultad de Ciencias Médicas
Teresita Tiznado Orozco, Modesto Orea Solano
Dendritic cells in the epidermis have an important role in the skin inmunity since they have an immunogenic capacity. The dendritic cell prototype is Langerhans cell (LC), however, nowadays it is known that there are other dendritic cells in the skin as dermic dendritic cells (DDCs). In this review we examined the functions and characteristics of these cells and their role in the atopic dermatitis.
May 2004: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
Shi-Fang Yuan, Kai-Zong Li, Ling Wang, Zhen Yan, Wei Han, Ying-Qi Zhang
AIM: To observe the specific cytotoxic T lymphocyte and humoral immune response induced by MUC1 DNA inmunization in mice. METHODS: Female BALB/c mice were immunized intramuscularly with 100 microg pcDNA3.1-MUC1 3 times at intervals of 3 weeks. Three weeks after the last immunization, tumor challenge experiments were performed by inoculation of MUC1 positive breast cancer cell line EMT6. Both humoral immune response and CTL-specific cytotoxicity were detected by immunohistochemical staining and (51)Cr release assay, respectively...
July 2003: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
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