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Mortality in hemodialysis

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https://www.readbyqxmd.com/read/29457529/n-terminal-pro-b-type-natriuretic-peptide-associated-with-2-year-mortality-from-both-cardiovascular-and-non-cardiovascular-origins-in-prevalent-chronic-hemodialysis-patients
#1
Chihiro Kawagoe, Yuji Sato, Tatsunori Toida, Hideto Nakagawa, Yasuhiro Yamashita, Akihiro Fukuda, Shuji Iwatsubo, Shouichi Fujimoto
N-terminal-pro-B-type-natriuretic peptide (NT-proBNP) was a predictive marker of cardiovascular disease (CVD)-related death in chronic dialysis patients. NT-proBNP was also correlated with markers of inflammation, malnutrition and protein-energy wasting. We hypothesized whether NT-proBNP was also associated with non-CVD death in chronic dialysis patients. A prospective observational study for incidence of death in chronic dialysis patients was conducted. Prevalent chronic dialysis patients (n = 1310) were enrolled and followed for 24 months...
November 2018: Renal Failure
https://www.readbyqxmd.com/read/29456217/vascular-access-mortality-and-hospitalization-among-hemodialysis-patients-in-palestine
#2
Sondus A Hamadneh, Saja A Nueirat, Jamal Qadoomi', Mohammed Shurrab, Wajeh Y Qunibi, Zakaria Hamdan
Vascular access complications are common in patients with end-stage kidney disease who are receiving maintenance hemodialysis (HD) and are responsible for an enormous burden of morbidity and mortality among these patients. Differences in the all-cause mortality rate and hospitalization between dialysis catheter use and arteriovenous (AV) vascular access use have not been documented in our HD population. We performed a 12-month prospective analysis of our HD patients from four dialysis centers. We examined all-cause mortality and hospitalization in patients being dialyzed through HD catheters as compared to patients with AV access...
January 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29456210/appraising-the-outcome-and-complications-of-peritoneal-dialysis-patients-in-self-care-peritoneal-dialysis-and-assisted-peritoneal-dialysis-a-5-year-review-of-a-single-saudi-center
#3
Jamal Saleh Al Wakeel, Mohammed A Al Ghonaim, Abdullah Aldohayan, Saira Usama, Saad Al Obaili, Ahmad R Tarakji, Mohammad Alkhowaiter
Our objective is to study the outcomes and complications of peritoneal dialysis (PD) including comparison of self-care PD with home-care assisted PD during a five-year period. A retrospective study of PD data at King Saud University-affiliated hospital in Riyadh from January 1, 2009, to December 31, 2013. One hundred and eleven patients were included (female 55%). The average age was 47.4 (1-83) years. Twenty-one (18.91%) patients were on continuous ambulatory PD and 90 (81.08%) on automated PD. The mean time on PD was 23...
January 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29456209/assessment-of-prevalence-and-clinical-outcome-of-frailty-in-an-elderly-predialysis-cohort-using-simple-tools
#4
Hatem Ali, Tarek Abdelaziz, Fatima Abdelaal, Jyoti Baharani
The relationship between frailty and chronic kidney disease in elderly population has been recognized; however, studies concentrating on frailty in predialysis patients are limited. For nephrologists, the recognition of frailty is important as it has impact on decisions on the choice of dialysis modality and sometimes on whether dialysis is indeed in the patients' best interests. Many of the tools for routine assessment of frailty are not easily applicable to those clinicians not practicing elderly care medicine...
January 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29456208/morbidity-and-mortality-of-hospitalized-hip-fractures-in-chronic-hemodialysis
#5
Georgios Vlachopanos, Theodoras Kassimatis, Anastasia Kokkona, Adamantia Zerva, Eirini Stavroulaki, Charilaos Zacharogiannis, Athanasios Agrafiotis
Abnormal bone architecture contributes to high incidence of hip fractures in chronichemodialysis (HD) patients. Their clinical epidemiology is incompletely described. We conducted a retrospective cohort study to assess the implications ofhospitalization with hip fracture in HD patients compared to the nonchronic kidney disease population. Thirty-three chronic HD patients admitted with hip fracture overfiveyears were age- and sex-matched on a 1:1 ratio with controls that had hip fracture and normal renal function...
January 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29456130/increments-in-serum-high-density-lipoprotein-cholesterol-over-time-are-not-associated-with-improved-outcomes-in-incident-hemodialysis-patients
#6
Tae Ik Chang, Elani Streja, Melissa Soohoo, Gang Jee Ko, Connie M Rhee, Csaba P Kovesdy, Moti L Kashyap, Nosratola D Vaziri, Kamyar Kalantar-Zadeh, Hamid Moradi
BACKGROUND: Elevated serum high-density lipoprotein cholesterol (HDL-C) has not been associated with better cardiovascular (CV) and all-cause mortality in hemodialysis patients. However, the association between change in HDL over time and mortality has not been fully examined. OBJECTIVE: In a nationally representative cohort of incident hemodialysis patients who had available HDL data at baseline and 6 months after dialysis initiation, we studied the association of change in HDL-C during the first 6 months of dialysis with all-cause and CV mortality...
January 31, 2018: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29454069/recipient-characteristics-and-morbidity-and-mortality-after-liver-transplantation
#7
Sumeet K Asrani, Giovanna Saracino, Jacqueline G O'Leary, Stevan Gonzales, Peter Kim, Greg McKenna, Goran Klintmalm, James Trotter
BACKGROUND: Over the last decade, liver transplantation of sicker, older non-hepatitis C cirrhotics with multiple co-morbidities has increased in the United States. METHODS: We sought to identify a parsimonious set of recipient factors among HCV negative adult transplant recipients associated with significant morbidity and mortality within 5 years after liver transplantation using national (n=31,829, 2002-2015) and center specific data. Coefficients of relevant recipient factors were converted to weighted points and scaled from 0-5...
February 14, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29452460/outcomes-after-surgical-pulmonary-embolectomy-for-acute-submassive-and-massive-pulmonary-embolism-a-single-center-experience
#8
Chetan Pasrija, Anthony Kronfli, Michael Rouse, Maxwell Raithel, Gregory J Bittle, Sheelagh Pousatis, Mehrdad Ghoreishi, James S Gammie, Bartley P Griffith, Pablo G Sanchez, Zachary N Kon
OBJECTIVES: Ideal treatment strategies for submassive and massive pulmonary embolism remain unclear. Recent reports of surgical pulmonary embolectomy have demonstrated improved outcomes, but surgical technique and postoperative outcomes continue to be refined. The aim of this study is to describe in-hospital survival and right ventricular function after surgical pulmonary embolectomy for submassive and massive pulmonary embolism with excessive predicted mortality (≥5%). METHODS: All patients undergoing surgical pulmonary embolectomy (2011-2015) were retrospectively reviewed...
March 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29441480/prognostic-value-of-cardiovascular-calcifications-in-hemodialysis-patients-a-longitudinal-study
#9
Nada Dimkovic, Georg Schlieper, Aleksandar Jankovic, Zivka Djuric, Marcus Ketteler, Tatjana Damjanovic, Petar Djuric, Jelena Marinkovic, Zoran Radojcic, Natasa Markovic, Jürgen Floege
PURPOSE: Cardiovascular calcifications (CVC) are present in up to 70% of non-diabetic dialysis patients. Sparse data are available on predictors of very long-term outcomes of such patients. The Belgrade Aachen Study on Calcification in Hemodialysis patients (BASCH study) aimed to study this using a comprehensive CVC assessment. METHODS: We prospectively analyzed 220 hemodialysis patients followed for a mean of 76 months (median 73 months, range 6-160 months). We compared patients deceased from cardiovascular diseases (CVD) and survivors...
February 13, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29440923/managing-hyperparathyroidism-in-hemodialysis-role-of-etelcalcetide
#10
REVIEW
Keith E Eidman, James B Wetmore
Secondary hyperparathyroidism (SHPT) is common in patients receiving maintenance hemodialysis and is associated with adverse outcomes. Currently, SHPT is managed by reducing circulating levels of phosphate with oral binders and parathyroid hormone (PTH) with vitamin D analogs and/or the calcimimetic cinacalcet. Etelcalcetide, a novel calcimimetic administered intravenously (IV) at the end of a hemodialysis treatment session, effectively reduces PTH in clinical trials when given thrice weekly. Additional clinical effects include reductions in circulating levels of phosphate and FGF-23 and an improved profile of markers of bone turnover...
2018: International Journal of Nephrology and Renovascular Disease
https://www.readbyqxmd.com/read/29439257/assessing-extracellular-volume-in-hemodialysis-patients-using-intradialytic-blood-pressure-slopes
#11
Hao Liu, Rong Lu, Shani Shastri, Mark Sonderman, Peter Noel Van Buren
BACKGROUND/AIMS: Extracellular volume (ECV) overload is a mortality risk factor in hemodialysis patients, but no standard approach exists to objectively assess this clinically. We aimed to quantify relationships between slopes of repeated intradialytic blood pressure (BP) measurements and ECV. METHODS: In a cross-sectional study of 71 hemodialysis patients, we calculated BP slopes from all intradialytic measurements using Gaussian regression. We measured extracellular and total body water (TBW) with bioimpedance spectroscopy...
February 13, 2018: Nephron
https://www.readbyqxmd.com/read/29436152/immersion-enhanced-fluid-redistribution-can-prevent-intradialytic-hypotension-a-prospective-randomized-crossover-clinical-trial
#12
Keren Doenyas-Barak, Nedal Garra, Ilia Beberashvili, Shai Efrati
INTRODUCTION: Intradialytic hypotension (IDH) is an important cause of morbidity and mortality among hemodialysis patients. We used an immersion model to evaluate the role of reduced effective circulating volume, and to examine whether facilitated refilling can prevent IDH. METHODS: Ten male hemodialysis patients who had frequent episodes of IDH were randomized to a mid-week "wet" or "dry" hemodialysis session, and subsequently underwent the other session in a crossover manner...
February 13, 2018: Hemodialysis International
https://www.readbyqxmd.com/read/29427181/toxic-alcohol-diagnosis-and-management-an-emergency-medicine-review
#13
REVIEW
Patrick Chow Yuen Ng, Brit J Long, William Tyler Davis, Daniel J Sessions, Alex Koyfman
Toxic alcohols are a group of substances containing a hydroxyl group not meant to be ingested. They are the cause of a significant number of accidental and non-accidental exposures. Toxic alcohol poisoning can be associated with a significant degree of morbidity and mortality if not promptly recognized and treated. This review describes the clinical presentation and an approach to the recognition and management for toxic alcohol poisoning. Toxic alcohols classically refer to a group of alcohols not meant for ingestion...
February 9, 2018: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/29426785/long-term-prognostic-impact-of-anticoagulation-on-patients-with-atrial-fibrillation-undergoing-hemodialysis
#14
Ruth María Sánchez Soriano, María Dolores Albero Molina, Carlos Israel Chamorro Fernández, Rocío Juliá-Sanchís, Ramón López Menchero, Carlos Del Pozo Fernández, Guillermo Grau Jornet, Julio Núñez Villota
INTRODUCTION AND OBJECTIVES: Evidence for the efficacy and safety of oral anticoagulation with dicumarines in patients with atrial fibrillation (AF) on hemodialysis is controversial. The aim of our study is to evaluate the long-term prognostic implications of anticoagulation with dicumarines in a cohort of patients with non-valvular AF on a hemodialysis program due to end-stage renal disease. METHODS: Retrospective, observational study with consecutive inclusion of 74 patients with AF on hemodialysis...
February 6, 2018: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29424185/predictors-of-early-failure-and-secondary-patency-in-native-arteriovenous-fistulas-for-hemodialysis
#15
Rui Abreu, Sara Rioja, Joaquin Vallespin, Xavier Vinuesa, Ruben Iglesias, Jose Ibeas
BACKGROUND: Native arteriovenous fistula (AVF) is considered the gold standard of vascular access for hemodialysis due to its longer survival, fewer complications, lower mortality and costs. Patency is important for effective dialysis treatment and this remains a challenge in nephrology. There are no well-defined prognostic factors for early and long-term AVF survival. The aim of this study was to evaluate comorbidity, analytical and ultrasound (US) variables as prognostic factors for early failure and AVF patency...
February 8, 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29423212/chronic-kidney-disease-kidney-transplantation-and-oxidative-stress-a-new-look-to-successful-kidney-transplantation
#16
Hossein Tabriziani, Michael S Lipkowitz, Nhan Vuong
Oxidative stress plays a key role in the pathophysiological process of uremia and its complications, particularly in cardiovascular disease. The level of oxidative stress markers is known to increase as chronic kidney disease progresses and correlates significantly with the level of renal function. Hemodialysis and peritoneal dialysis are major modes of renal replacement therapy for end-stage renal disease patients, but unfortunately they are also accompanied by increased oxidative stress. Successful kidney transplantation, however, results in near normalization of the antioxidant status and lipid metabolism by eliminating free radicals despite the surge of oxidative stress caused by the surgical procedure and ischemic injury to the organ during the operation...
February 2018: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29422067/predictors-of-hospital-mortality-in-adult-trauma-patients-receiving-extracorporeal-membrane-oxygenation-for-advanced-life-support-a-retrospective-cohort-study
#17
Meng-Yu Wu, Pin-Li Chou, Tzu-I Wu, Pyng-Jing Lin
BACKGROUND: Using extracorporeal membrane oxygenation (ECMO) to provide advanced life support in adult trauma patients remains a controversial issue now. The study was aimed at identifying the independent predictors of hospital mortality in adult trauma patients receiving ECMO for advanced cardiopulmonary dysfunctions. METHODS: This retrospective study enrolled 36 adult trauma patients receiving ECMO due to advanced shock or respiratory failure in a level I trauma center between August 2006 and October 2014...
February 8, 2018: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/29421796/variability-in-predialysis-systolic-blood-pressure-and-long-term-outcomes-in-hemodialysis-patients
#18
Ying Wang, Yan Qin, Xiaohong Fan, Jianfang Cai, Wei Ye, Jinghua Xia, Mingxi Li, Xuemei Li, Xuewang Li, Limeng Chen
BACKGROUND/AIMS: While systolic blood pressure variability (SBPV) is an independent risk factor for mortality in the general population, its association with outcomes in hemodialysis patients has been less well-investigated. METHODS: In this retrospective study, we enrolled 99 eligible HD patients from 2006 to 2016. Predialysis blood pressure measurements obtained over 1-year period were used to determine each patient's BPV. The standard deviation (SD), the coefficient of variation (CV) and the variation independent of the mean (VIM) were used as metrics of BPV...
January 31, 2018: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29415829/evaluation-of-curcumin-s-effect-on-inflammation-in-hemodialysis-patients
#19
Fariba Samadian, Nooshin Dalili, Fatemeh Poor-Reza Gholi, Mahtab Fattah, Narges Malih, Mohsen Nafar, Ahmad Firoozan, Pedram Ahmadpoor, Shiva Samavat, Shadi Ziaie
OBJECTIVE: Despite advances in prevention of inflammatory milieu with different anti-inflammatory modalities in hemodialysis patients the rate of inflammatory markers in this population are still high. Inflammation is considered as a major player in uremia associated with morbidity and mortality in hemodialysis patients. The aim of this study was to evaluate the turmeric s effects on reduction of inflammatory markers in hemodialysis patients. METHODS: Hemodialysis patients over 18 years were recruited after fulfilling the inclusion criteria...
December 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29414834/phosphate-removal-during-conventional-hemodialysis-a-decades-old-misconception
#20
Rosilene M Elias, Valeria R C Alvares, Rosa M A Moysés
BACKGROUND/AIMS: Hyperphosphatemia is associated with high mortality rate in patients on dialysis. Conventional hemodialysis (HD) is a limit technique in removing phosphate (P). There is a widespread belief that P is removed mainly in the first hour of HD. The aim of this study was to certify the percentage of 1-hour removal of P as compared to the entire procedure. METHODS: data from the first dialysis of the week of 21 patients (13 men, age 44±15 years), for 3 consecutive dialysis sessions were evaluated...
January 31, 2018: Kidney & Blood Pressure Research
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