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https://www.readbyqxmd.com/read/29663938/cohousing-male-mice-with-and-without-segmental-bone-defects
#1
Jeffrey D Rytlewski, Paul J Childress, David C Scofield, Faisal Khan, Marta B Alvarez, Aamir T Tucker, Jonathan S Harris, Jessica L Peveler, Debra L Hickman, Tien-Min G Chu, Melissa A Kacena
Spaceflight results in bone loss like that associated with osteoporosis or decreased weight-bearing (for example, high-energy trauma such as explosive injuries and automobile accidents). Thus, the unique spaceflight laboratory on the International Space Station presents the opportunity to test bone healing agents during weightlessness. We are collaborating with NASA and the US Army to study bone healing in spaceflight. Given the unique constraints of spaceflight, study design optimization was required. Male mice were selected primarily because their femur is larger than females', allowing for more reproducible surgical outcomes...
April 2, 2018: Comparative Medicine
https://www.readbyqxmd.com/read/29658926/evaluation-of-stem-cell-therapies-in-a-bilateral-patellar-tendon-injury-model-in-rats
#2
John R Wagner, Takashi Taguchi, Jane Y Cho, Chandrashekhar Charavaryamath, Dominique J Griffon
Regenerative medicine provides novel alternatives to conditions that challenge traditional treatments. The prevalence and morbidity of tendinopathy across species, combined with the limited healing properties of this tissue, have prompted the search for cellular therapies and propelled the development of experimental models to study their efficacy. Umbilical cord matrix-derived mesenchymal stem cells (UCM-MSC) are appealing candidates because they are abundant, easy to collect, circumvent the ethical concerns and risk of teratoma formation, yet resemble primitive embryonic stem cells more closely than adult tissue-derived MSCs...
March 30, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29658112/the-influential-factors-on-the-morphological-changes-of-upper-airway-associated-with-mouth-opening
#3
Bin Hu, Jingying Ye, Guoping Yin, Yuhuan Zhang
OBJECTIVE: This study aimed to evaluate the influential factors on the morphological changes of upper airway caused by mouth opening (MO). METHODS: One hundred and thirty-eight obstructive sleep apnea-hypopnea syndrome (OSAHS) patients were enrolled. Anthropometric and demographic data, Friedman tongue position (FTP), and tonsil scores were recorded. Overnight polysomnography and upper airway computed tomography scans under two conditions (mouth closed [MC] and MO) were acquired...
April 15, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29656064/a-prospective-study-of-patient-reported-pain-after-bulbar-urethroplasty
#4
Patrick Evans, Sorena Keihani, Benjamin N Breyer, Bradley A Erickson, James M Hotaling, Sara M Lenherr, Jeremy B Myers
PURPOSE: To understand the prevalence of chronic perineal pain, activity limitations, and patient satisfaction after urethroplasty. METHODS: From 2014-2016, we prospectively enrolled men undergoing urethroplasty for bulbar urethral strictures. Patients, before and after surgery, completed questions from the Core Lower Urinary Tract Symptom Score (CLSS) assessing pain frequency in the bladder and penis/urethra, as well as non-validated questions assessing perineal pain...
April 12, 2018: Urology
https://www.readbyqxmd.com/read/29652032/prevalence-and-clinical-predictors-of-lpr-among-patients-diagnosed-with-gerd-according-to-the-reflux-symptom-index-questionnaire
#5
Mahmoud Mosli, Bashaer Alkhathlan, Abdulmalik Abumohssin, Mazin Merdad, Ameen Alherabi, Osama Marglani, Hani Jawa, Talal Alkhatib, Hani Z Marzouki
Background/Aims: Gastroesophageal reflux disease (GERD) is a common condition that can lead to significant morbidity. Laryngopharyngeal reflux (LPR) is a distinct clinical entity that can occur simultaneously with GERD, necessitating additional treatment measures. The degree of overlap and clinical predictors of LPR among patients with GERD remains unknown. We aim to measure the prevalence of LPR in patients with GERD and identify clinical predictors. Patients and Methods: We performed a cross-sectional study involving patients with confirmed GERD according to the GERD questionnaire (GerdQ) using the reflux symptom index (RSI)...
April 13, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29642681/the-effect-of-nutrition-and-body-condition-of-triplet-bearing-ewes-during-late-pregnancy-on-the-behaviour-of-ewes-and-lambs
#6
Gabriella V Gronqvist, Rene A Corner-Thomas, Paul R Kenyon, Kevin J Stafford, Stephen T Morris, Rebecca Edith Hickson
Objective: Triplet-born lambs are less likely to survive to weaning than twin-born or single-born lambs. Appropriate ewe-lamb bonding behaviours and lamb vigour behaviours are necessary for survival of lambs. The aim of this experiment was to determine whether maternal nutrition during late pregnancy influenced behaviour of the ewe and her lambs soon after birth, and to determine whether mid-pregnancy body condition score (BCS) influenced any behavioural response. Methods: The experiments included ewes that were in BCS 2...
April 12, 2018: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/29629635/juror-decision-making-in-acquaintance-and-marital-rape-the-influence-of-clothing-alcohol-and-preexisting-stereotypical-attitudes
#7
Kirsty Osborn, Josh P Davis, Susan Button, John Foster
Stereotypical biases about women's roles in intimate relationships including their marital status and lifestyle choices such as clothing and alcohol use influence juror attributions of rape case defendant guilt, potentially reducing access to justice for victims. Across two mock-juror decision-making experiments, participants read identical fictitious sexual assault vignettes varying in intoxicated defendant-complainant relationship (married vs. acquaintance), accompanied by photographs of complainant clothing at the crime (body revealing vs...
April 1, 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29628881/posture-motor-and-posture-ideomotor-dual-tasking-a-putative-marker-of-psychomotor-retardation-and-depressive-rumination-in-patients-with-major-depressive-disorder
#8
Lyubomir I Aftanas, Olga M Bazanova, Nataliya V Novozhilova
Background: Recent studies have demonstrated that the assessment of postural performance may be a potentially reliable and objective marker of the psychomotor retardation (PMR) in the major depressive disorder (MDD). One of the important facets of MDD-related PMR is reflected in disrupted central mechanisms of psychomotor control, heavily influenced by compelling maladaptive depressive rumination. In view of this we designed a research paradigm that included sequential execution of simple single-posture task followed by more challenging divided attention posture tasks, involving concurring motor and ideomotor workloads...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29627608/effect-of-wheelchair-stroke-pattern-on-upper-extremity-muscle-fatigue
#9
Brittany Bickelhaupt, Sakiko Oyama, Jonathan Benfield, Keith Burau, Shuko Lee, Michelle Trbovich
BACKGROUND: Shoulder dysfunction is common in persons with spinal cord injury (SCI) with an incidence of up to 63%1 . Dysfunction is a result of muscle imbalances, specifically denervated rotator cuff muscles that are repetitively used during manual wheelchair propulsion. OBJECTIVE: To determine which arm stroke technique, pump (P) or semicircular (SC), is most energy efficient for long periods of propulsion. DESIGN: A small randomized study with repeated-measures observations...
April 5, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29627253/yeast-culture-increased-plasma-niacin-concentration-evaporative-heat-loss-and-feed-efficiency-of-dairy-cows-in-a-hot-environment
#10
Julia D L Dias, Rayana B Silva, Tatiane Fernandes, Eugenio F Barbosa, Larissa E C Graças, Rafael C Araujo, Renata A N Pereira, Marcos N Pereira
The supplementation of dairy cows with yeast culture may increase diet digestibility, plasma niacin concentration, heat dissipation, and lactation performance. Our objective was to evaluate the response of Holstein cows in late lactation (234 ± 131 d in milk) to dead yeast culture (YC, 15 g/d, Factor SC, GRASP, Saccharomyces cerevisiae) during Brazilian summer (temperature-humidity index >68 for 92.2% of the time). Thirty-two cows were individually fed a standard total mixed ration for 14 d and control (CTL) or YC treatments for 35 d, in a covariate adjusted complete randomized block design...
April 4, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29627246/robustness-and-sensitivity-of-a-blueprint-for-on-farm-estimation-of-dairy-cow-energy-balance
#11
Vivi M Thorup, Mizeck G G Chagunda, Amelie Fischer, Martin R Weisbjerg, Nicolas C Friggens
Excessive negative energy balance (EB) has been associated with decreased reproductive performance and increased risk of lameness and metabolic diseases. On-farm, automated EB estimates for individual cows would enable dairy farmers to detect excessive negative EB early and act to minimize its extent and duration by altering feeding. Previously, we have shown that EB can be estimated from frequent measurements of body weight (BW) and body condition score (BCS) changes, referred to as EBbody . In this study, we investigated the robustness and sensitivity of the EBbody method to assess its genericity and on-farm applicability...
April 4, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29627241/influence-of-adipocyte-size-and-adipose-depot-on-the-number-of-adipose-tissue-macrophages-and-the-expression-of-adipokines-in-dairy-cows-at-the-end-of-pregnancy
#12
E Depreester, J De Koster, M Van Poucke, M Hostens, W Van den Broeck, L Peelman, G A Contreras, G Opsomer
The aim of this study was to determine the number of adipose tissue macrophages (ATM) and the mRNA expression of adipokines [adiponectin (ADIPOQ), leptin (LEP), interleukin 6 (IL6), tumor necrosis factor (TNF), and interleukin 10 (IL10)] in different adipose depots from cows with a variable body condition score (BCS) at the end of the dry period. We hypothesized that the number of ATM and the expression of these adipokines depend on adipocyte size and the anatomical location of the adipose depot. Subcutaneous, omental, mesenteric, perirenal, and intrapelvic adipose tissue samples were taken immediately after euthanasia of 10 Holstein Friesian dairy cows (upcoming parity 2 to 5, age 3...
April 4, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29624596/embodied-pain-in-fibromyalgia-disturbed-somatorepresentations-and-increased-plasticity-of-the-body-schema
#13
Endika Martínez, Zigor Aira, Itsaso Buesa, Ibane Aizpurua, Diego Rada, Jon Jatsu Azkue
Fibromyalgia syndrome (FMS) is a highly prevalent, chronic musculoskeletal condition characterized by widespread pain and evoked pain at tender points. This study evaluated various aspects of body awareness in a sample of 14 women with FMS and 13 healthy controls, such as plasticity of the body schema, body esteem, and interoceptive awareness. To this end, the Rubber Hand Illusion (RHI), the Body Esteem Scale (BES), and the Body Perception Questionnaire (BPQ) were used, respectively. Consistent with increased plasticity of the body schema, FMS patients scored higher, with large or very large effect sizes, across all three domains evaluated in the RHI paradigm, namely proprioceptive drift and perceived ownership and motor control over the rubber hand...
2018: PloS One
https://www.readbyqxmd.com/read/29622474/the-burden-of-not-weighted-factors-nursing-workload-in-a-medical-intensive-care-unit
#14
Enrico Giuliani, Giovanni Lionte, Paola Ferri, Alberto Barbieri
OBJECTIVES: Body weight and infection status affect nursing workload and are not accounted for in the Therapeutic Intervention Scoring System 28 (TISS-28) and Nine Equivalents of Nursing Manpower Use Score (NEMS). The objective of this study was to analyse the correlation between weight and infection status with TISS 28 and NEMS in a cohort of medical Intensive Care Unit patients. RESEARCH METHODOLOGY: A retrospective observational trial was conducted on the nursing records of 26 randomly selected patients over a 12-month period...
April 2, 2018: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/29618013/fgf21-is-associated-with-metabolic-effects-and-treatment-response-in-depressed-bipolar-ii-disorder-patients-treated-with-valproate
#15
Hui Hua Chang, Po See Chen, Yung Wen Cheng, Tzu-Yun Wang, Yen Kuang Yang, Ru-Band Lu
Background: Patients with bipolar disorder are at high risk of metabolic disturbance after mood stabilizer treatment. However, the mediators linking the two conditions remain unknown. In this study, we investigated whether fibroblast growth factor-21 (FGF21) was associated with metabolic effects and treatment response in depressed bipolar disorder patients. Methods: We recruited 78 community-dwelling controls and 137 bipolar disorder patients; the latter were interviewed using the Chinese Version of the Modified Schedule of Affective Disorder and Schizophrenia-Life Time...
April 1, 2018: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29617471/hypophosphatemic-rickets-case-report
#16
Marta Liliane de Almeida Maia, Ana Lucia Santos Abreu, Paulo Cesar Koch Nogueira, Maria Luiza Dautro Moreira do Val, João Tomas de Abreu Carvalhaes, Maria Cristina de Andrade
OBJECTIVE: Early diagnosis and immediate treatment of hypophosphatemic rickets is of utmost importance as it may prevent subsequent sequelae. This report aims at warning pediatricians to consider the presence of the disease. CASE DESCRIPTION: Description of the metabolic profile, creatinine clearance, nutritional status, weight and body structure of a patient who presented the clinical-laboratorial characteristics of hypophosphatemic rickets and was followed in an outpatient clinic for tubulopathies over the period of 12 months...
March 29, 2018: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/29613996/timing-and-predictors-of-mild-and-severe-heat-illness-among-new-military-enlistees
#17
D Alan Nelson, Patricia A Deuster, Francis G OʼConnor, Lianne M Kurina
PURPOSE: Heat illnesses are important and potentially fatal conditions among physically active individuals. We determined predictors of heat illness among enlistees in a large military population experiencing common physical activity patterns. METHODS: We estimated the adjusted odds of mild and severe heat illness associated with demographic, health-related, and geographic factors among active-duty, United States Army soldiers enlisting between January 2011 - December 2014 (N=238,168) using discrete-time multivariable logistic regression analyses...
April 27, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29608999/experimental-effects-of-acute-exercise-and-music-listening-on-cognitive-creativity
#18
Emily Frith, Paul D Loprinzi
OBJECTIVE: The purpose of this study was to extend previous experimental work suggesting that both exercise and music-based interventions may influence creativity processes, by investigating the independent influences of exercise or music stimuli on verbal creative performances in the laboratory environment. METHODS: 32 students at the University of Mississippi participated in this within-subject intervention, which included three laboratory visits per participant...
March 30, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29608076/body-image-and-self-esteem-in-disorders-of-sex-development-a-european-multicenter-study
#19
Tim C van de Grift, Peggy T Cohen-Kettenis, Annelou L C de Vries, Baudewijntje P C Kreukels
OBJECTIVE: Disorders/differences of sex development (DSD) refer to congenital conditions with atypical sex development and are associated with psychosexual issues. The aim of this study was to assess body image and self-esteem across the DSD spectrum and to study the impact of diagnosis and mediating characteristics. METHOD: Data collection was part of dsd-LIFE, a cross-sectional study conducted by 14 European expert clinics on wellbeing and health care evaluation of adults diagnosed with DSD...
April 2018: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/29607474/health-related-quality-of-life-of-the-elderly-in-institutional-care-and-non-institutional-care-in-southwestern-nigeria-a-comparative-study
#20
A O Ogunyemi, K A Odeyemi, O J Kanma-Okafor, T W Ladi-Akinyemi
BACKGROUND: The world population is rapidly ageing and people aged 60 years and above are growing faster than any other age group. In Africa, the most rapid growth of older persons is expected in Western and Northern Africa. STUDY DESIGN: This was a comparative cross-sectional study of a total of 360 respondents. A multi-stage sampling method was used in selecting 240 respondents in the non-institutional group while all the respondents (120) in the institutional group were included in the study...
January 2018: West African Journal of Medicine
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