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https://www.readbyqxmd.com/read/29651598/geriatric-assessment-for-older-patients-with-non-small-cell-lung-cancer-daily-practice-of-centers-participating-in-the-nvalt25-eldapt-trial
#1
Elisabeth J M Driessen, Judith G M van Loon, Huub A Maas, Anne-Marie C Dingemans, Maryska L G Janssen-Heijnen
INTRODUCTION: Geriatric assessment (GA) for older patients with lung cancer could provide insight into vulnerability, cognitive impairment, and risk of toxicity. Discontinuation and complications of intensive treatment could potentially be prevented in vulnerable and frail patients. This study aimed to evaluate current clinical practice of GA for older patients with lung cancer in the Netherlands and identify potential hurdles for implementation. METHODS: Pulmonologists and radiation oncologists participating in the NVALT25-ELDAPT trial completed an online questionnaire regarding current practice of GA, added value of GA for treatment decision-making and logistic barriers for patients with non-small cell lung cancer...
April 12, 2018: Lung
https://www.readbyqxmd.com/read/29650190/improving-the-utilization-of-health-services-among-high-risk-pregnant-women-through-community-health-nurse-assistance
#2
Asti Melani Astari, Yeni Rustina, Hadi Pratomo, Sabarinah B Prasetyo
OBJECTIVE: The objective of this study was to identify the impact of implementing community health nurse assistance for high-risk pregnant women on utilization of health services. METHOD: The study was quasi experimental with a control group design. The sample included high-risk pregnant women in 10 community health centers in Indonesia who were selected by consecutive sampling. The total sample included 66 women in both the intervention and the control groups. The high-risk pregnant women in the intervention group received nurses' assistance during the third trimester and until giving birth...
February 2018: Enfermería Clínica
https://www.readbyqxmd.com/read/29629790/the-association-between-adverse-childhood-experience-ace-and-school-success-in-elementary-school-children
#3
Christopher Blodgett, Jane D Lanigan
We explored the feasibility of using school personnel as reporters to examine the relationship between the level of adverse childhood experiences (ACEs) exposure in a nonclinical sample of public elementary schoolchildren and academic risk. We selected a random sample of 2,101 children from kindergarten through 6th grade classroom rosters at 10 elementary schools. Students were 50% male, 78% White, and 55% free and reduced meal program participants. School personnel reported their factual knowledge of 10 ACEs and academic risk in a database controlled by the schools...
March 2018: School Psychology Quarterly
https://www.readbyqxmd.com/read/29629328/knowledge-attitudes-and-practices-among-health-care-providers-regarding-zika-virus-infection
#4
Swati Sharma, Apurva Tyagi, Sujatha Ramachandra, Lipsa Bhuyan, Kailash Chandra Dash, Malvika Raghuvanshi
Aims and Objectives: Zika virus (ZIKV) is a mosquito-borne flavivirus that was first identified in Uganda in 1947 in monkeys. The study was designed to assess the knowledge, attitude, and practices regarding ZIKV infection among rural health-care providers in Aligarh district, Uttar Pradesh, India. Materials and Methods: A total of 600 health-care providers were selected through stratified random sampling in an interventional survey. A self-structured, closed-ended questionnaire was administered to each participant in two phases to record their demographic, professional characteristics, knowledge, attitude, and practices regarding ZIKV...
January 2018: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/29625608/the-obesogenic-environment-around-elementary-schools-food-and-beverage-marketing-to-children-in-two-mexican-cities
#5
Simón Barquera, Lucia Hernández-Barrera, Stephen J Rothenberg, Enrique Cifuentes
BACKGROUND: Unhealthy environments and food advertisements are major determinants of childhood obesity. Recent regulation has banned unhealthy foods from schools in Mexico. However, currently there is no regulation limiting exposure to food marketing around schools. Thus, our objective was to analyze the characteristics of food advertising practices around 60 elementary schools in two cities and to evaluate compliance with the Pan American Health Organization (PAHO) recommendations and the local food industry self-regulatory marketing code...
April 7, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29619075/in-vitro-toxicological-evaluation-of-surgical-smoke-from-human-tissue
#6
Jennifer D Sisler, Justine Shaffer, Jhy-Charm Soo, Ryan F LeBouf, Martin Harper, Yong Qian, Taekhee Lee
Background: Operating room personnel have the potential to be exposed to surgical smoke, the by-product of using electrocautery or laser surgical device, on a daily basis. Surgical smoke is made up of both biological by-products and chemical pollutants that have been shown to cause eye, skin and pulmonary irritation. Methods: In this study, surgical smoke was collected in real time in cell culture media by using an electrocautery surgical device to cut and coagulate human breast tissues...
2018: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/29616653/accessibility-of-cesarean-deliveries-in-benin
#7
V Mongbo, J Saïzonou, G Sopoh, C Sossa-Jérôme, E M Ouendo, I Godin
To be used effectively, emergency obstetric and neonatal care must be available and accessible. This study sought to measure the accessibility of cesarean deliveries in Benin. Cross-sectional study of randomly selected women in each of the 12 obstetrics departments in Benin. Geographical accessibility was measured by estimating the distance between the parturientes residence and the hospital. Financial accessibility was the average direct cost of the cesarean delivery -the sum of medical and non-medical costs...
February 1, 2018: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/29610129/ultrasound-for-lower-extremity-deep-venous-thrombosis-multidisciplinary-recommendations-from-the-society-of-radiologists-in-ultrasound-consensus-conference
#8
REVIEW
Laurence Needleman, John J Cronan, Michael P Lilly, Geno J Merli, Srikar Adhikari, Barbara S Hertzberg, M Robert DeJong, Michael B Streiff, Mark H Meissner
Venous ultrasound is the standard imaging test for patients suspected of having acute deep venous thrombosis (DVT). There is variability and disagreement among authoritative groups regarding the necessary components of the test. Some protocols include scanning the entire lower extremity, whereas others recommend scans limited to the thigh and knee supplemented with serial testing. Some protocols use gray-scale ultrasound alone, whereas others include Doppler interrogation. Point-of-care ultrasound is recommended in some settings, and there is heterogeneity of these protocols as well...
April 3, 2018: Circulation
https://www.readbyqxmd.com/read/29608170/multiplexed-isothermal-amplification-based-diagnostic-platform-to-detect-zika-chikungunya-and-dengue-1
#9
Ozlem Yaren, Barry W Alto, Kevin M Bradley, Patricia Moussatche, Lyudmyla Glushakova, Steven A Benner
Zika, dengue, and chikungunya viruses are transmitted by mosquitoes, causing diseases with similar patient symptoms. However, they have different downstream patient-to-patient transmission potentials, and require very different patient treatments. Thus, recent Zika outbreaks make it urgent to develop tools that rapidly discriminate these viruses in patients and trapped mosquitoes, to select the correct patient treatment, and to understand and manage their epidemiology in real time. Unfortunately, current diagnostic tests, including those receiving 2016 emergency use authorizations and fast-track status, detect viral RNA by reverse transcription polymerase chain reaction (RT-PCR), which requires instrumentation, trained users, and considerable sample preparation...
March 13, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29606655/should-dental-schools-invest-in-training-predoctoral-students-for-academic-careers-two-viewpoints-viewpoint-1-dental-schools-should-add-academic-careers-training-to-their-predoctoral-curricula-to-enhance-faculty-recruitment-and-viewpoint-2-addition-of-academic
#10
Brent Fung, Mahnaz Fatahzadeh, Keith L Kirkwood, Jeffery Hicks, Sherry R Timmons
This Point/Counterpoint considers whether providing dental students with academic career training and teaching experiences during their predoctoral education would be valuable to recruit dental academicians. While training the next generation of dentists continues to be the primary focus for dental schools, the cultivation and recruitment of dental faculty members from the pool of dental students remain challenges. Viewpoint 1 supports the position that providing dental students with exposure to academic career opportunities has positive value in recruiting new dental faculty...
April 2018: Journal of Dental Education
https://www.readbyqxmd.com/read/29606016/laboratory-diagnosis-of-lyme-borreliosis-current-state-of-the-art-and-future-perspectives
#11
Benedikt Lohr, Volker Fingerle, Douglas E Norris, Klaus-Peter Hunfeld
This review is directed at physicians and laboratory personnel in private practice and clinics who treat and diagnose Lyme borreliosis (LB) in patients as part of their daily work. A major objective of this paper is to bring together background information on Borrelia (B.) burgdorferi sensu lato (s.l.) and basic clinical knowledge of LB, which is one of the most frequently reported vector-borne diseases in the Northern Hemisphere. The goal is to provide practical guidance for clinicians and for laboratory physicians, and scientists for a better understanding of current achievements and ongoing obstacles in the laboratory diagnosis of LB, an infectious disease that still remains one of the diagnostic chameleons of modern clinical medicine...
April 2, 2018: Critical Reviews in Clinical Laboratory Sciences
https://www.readbyqxmd.com/read/29596532/intention-to-quit-and-the-role-of-dark-personality-and-perceived-organizational-support-a-moderation-and-mediation-model
#12
Luke Treglown, Katarina Zivkov, Anthony Zarola, Adrian Furnham
This study investigated the role of individual differences (dark personality) and situational factors (perceived organisational support) in explaining intention to quit. Four hundred and fifty-one (50 of which females) ambulance personnel completed three questionnaires (Hogan Development Survey; Perceived Organisational Support Survey; and a single item Intention to Quit measure) as a part of a selection and development assessment. Employees high on Excitable, Sceptical, and Mischievous, but low on Colourful were found to have greater intentions to quit...
2018: PloS One
https://www.readbyqxmd.com/read/29594017/multivariable-risk-based-patient-selection-for-prostate-biopsy-in-a-primary-health-care-setting-referral-rate-and-biopsy-results-from-a-urology-outpatient-clinic
#13
Daniël F Osses, Arnout R Alberts, Gonny C F Bausch, Monique J Roobol
Background: According to their guidelines, Dutch general practitioners (GPs) refer men with prostate-specific antigen (PSA) level ≥3.0 ng/mL to the urologist for risk-based patient selection for prostate biopsy using the Rotterdam Prostate Cancer Risk Calculator (RPCRC). Use of the RPCRC in primary care could optimize the diagnostic pathway even further by reducing unnecessary referrals. To investigate this, we calculated the risk and assessed the rate of men referred to the urologist with PSA level ≥3...
February 2018: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29592840/doravirine-versus-ritonavir-boosted-darunavir-in-antiretroviral-naive-adults-with-hiv-1-drive-forward-48-week-results-of-a-randomised-double-blind-phase-3-non-inferiority-trial
#14
Jean-Michel Molina, Kathleen Squires, Paul E Sax, Pedro Cahn, Johan Lombaard, Edwin DeJesus, Ming-Tain Lai, Xia Xu, Anthony Rodgers, Lisa Lupinacci, Sushma Kumar, Peter Sklar, Bach-Yen Nguyen, George J Hanna, Carey Hwang
BACKGROUND: Doravirine is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) with a pharmacokinetic profile supporting once-daily dosing, and potent in-vitro activity against the most common NNRTI-resistant HIV-1 variants. We compared doravirine with ritonavir-boosted darunavir, when both were given with two nucleoside reverse transcriptase inhibitors (NRTIs), in adults with previously untreated HIV-1 infection. METHODS: In this randomised, controlled, double-blind, multicentre, non-inferiority trial, adults with HIV-1 infection were screened and enrolled at 125 clinical centres in 15 countries...
March 23, 2018: Lancet HIV
https://www.readbyqxmd.com/read/29590473/disability-rating-age-at-death-and-cause-of-death-in-u-s-veterans-with-service-connected-conditions
#15
Charles Maynard, Ranak Trivedi, Karin Nelson, Stephan D Fihn
Introduction: The association between disability and cause of death in Veterans with service-connected disabilities has not been studied. The objective of this study was to compare age at death, military service and disability characteristics, including disability rating, and cause of death by year of birth. We also examined cause of death for specific service-connected conditions. Materials and methods: This study used information from the VETSNET file, which is a snapshot of selected items from the Veterans Benefits Administration corporate database...
March 26, 2018: Military Medicine
https://www.readbyqxmd.com/read/29580189/occupational-exposure-monitoring-data-collection-storage-and-use-among-state-based-and-private-workers-compensation-insurers
#16
Taylor M Shockey, Kelsey R Babik, Steven J Wurzelbacher, Libby L Moore, Michael S Bisesi
Despite substantial financial and personnel resources being devoted to occupational exposure monitoring (OEM) by employers, workers' compensation insurers, and other organizations, the United States (US) lacks comprehensive occupational exposure databases to use for research and surveillance activities. OEM data are necessary for determining the levels of workers' exposures; compliance with regulations; developing control measures; establishing worker exposure profiles; and improving preventive and responsive exposure surveillance and policy efforts...
March 26, 2018: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/29571230/analysis-of-factors-related-to-failure-in-the-pressure-test-a-six-year-experience-in-taiwan
#17
Wei-Shih Tseng, Man-Yuan Huang, Hui-Chieh Lee, Wen-Shyan Huang, Bor-Hwang Kang
Introduction: The Republic of China Navy instituted the pressure test as one of the selection tools for diving troops and submarine crews. We analyzed factors associated with failure in the pressure test. Methods: This was a retrospective cohort study designed to investigate pressure test failure in Navy recruits between January 2010 and August 2015. The recruits received pressurization in a hyperbaric chamber to a simulated depth of 112 feet of seawater (fsw) at a rate of 25 fsw/minute...
January 2018: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29563775/development-of-small-bisquaternary-cholinesterase-inhibitors-as-drugs-for-pre-treatment-of-nerve-agent-poisonings
#18
Kamil Kuca, Jana Zdarova Karasova, Ondrej Soukup, Jiri Kassa, Eva Novotna, Vendula Sepsova, Anna Horova, Jaroslav Pejchal, Martina Hrabinova, Eva Vodakova, Daniel Jun, Eugenie Nepovimova, Martin Valis, Kamil Musilek
Background: Intoxication by nerve agents could be prevented by using small acetylcholinesterase inhibitors (eg, pyridostigmine) for potentially exposed personnel. However, the serious side effects of currently used drugs led to research of novel potent molecules for prophylaxis of organophosphorus intoxication. Methods: The molecular design, molecular docking, chemical synthesis, in vitro methods (enzyme inhibition, cytotoxicity, and nicotinic receptors modulation), and in vivo methods (acute toxicity and prophylactic effect) were used to study bispyridinium, bisquinolinium, bisisoquinolinium, and pyridinium-quinolinium/isoquinolinium molecules presented in this study...
2018: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29562812/balanced-scorecard-based-performance-evaluation-of-chinese-county-hospitals-in-underdeveloped-areas
#19
Hongda Gao, He Chen, Jun Feng, Xianjing Qin, Xuan Wang, Shenglin Liang, Jinmin Zhao, Qiming Feng
Objective Since the Guangxi government implemented public county hospital reform in 2009, there have been no studies of county hospitals in this underdeveloped area of China. This study aimed to establish an evaluation indicator system for Guangxi county hospitals and to generate recommendations for hospital development and policymaking. Methods A performance evaluation indicator system was developed based on balanced scorecard theory. Opinions were elicited from 25 experts from administrative units, universities and hospitals and the Delphi method was used to modify the performance indicators...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29560801/analysis-of-human-and-organizational-factors-that-influence-mining-accidents-based-on-bayesian-network
#20
Mostafa Mirzaei Aliabadi, Hamed Aghaei, Omid Kalatpour, Ali Reza Soltanian, Asghar Nikravesh
PURPOSE: The present study was aimed to analyze human and organizational factors involved in mining accidents and determine the relationships among these factors. MATERIALS AND METHODS: In this study, Human Factors Analysis and Classification System (HFACS) with Bayesian network (BN) were combined in order to analyze contributing factors in mining accidents. BN was constructed based on a hierarchal structure of HFACS. The required data were collected from a total of 295 cases of Iranian mining accidents and analyzed using HFACS...
March 21, 2018: International Journal of Occupational Safety and Ergonomics: JOSE
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