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https://www.readbyqxmd.com/read/28817825/muscle-strength-and-muscle-mass-in-older-patients-during-hospitalization-the-empower-study
#1
Jeanine M Van Ancum, Kira Scheerman, Vincent D Pierik, Siger T Numans, Sjors Verlaan, Hanne E Smeenk, Monique Slee-Valentijn, Roeliene C Kruizinga, Carel G M Meskers, Andrea B Maier
BACKGROUND: Low muscle strength and muscle mass are associated with an increased length of hospital stay and higher mortality rate in inpatients. To what extent hospitalization affects muscle strength and muscle mass is unclear. OBJECTIVE: We aimed to assess muscle strength and muscle mass at admission and during hospitalization in older patients and its relation with being at risk of geriatric conditions. METHODS: The EMPOWER study included patients aged 70 years and older, admitted to 4 wards of the VU University Medical Center in the Netherlands between April and December 2015...
August 18, 2017: Gerontology
https://www.readbyqxmd.com/read/28817452/cms-mds-3-0-section-m-skin-conditions-in-long-term-care-pressure-ulcers-skin-tears-and-moisture-associated-skin-damage-data-update
#2
Elizabeth A Ayello
GENERAL PURPOSE: The purpose of this learning activity is to provide information about the updates to the Centers for Medicare & Medicaid Services (CMS) MDS 3.0 Section M, Skin Conditions documentation in long-term care. TARGET AUDIENCE: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES: After participating in this educational activity, the participant should be better able to:1...
September 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/28817439/faculty-development-for-the-operating-room-an-examination-of-the-effectiveness-of-an-intraoperative-teaching-course-for-surgeons
#3
Aimee K Gardner, Matthew D Timberlake, Brian J Dunkin
OBJECTIVE: We describe a half-day faculty development course designed to equip surgical educators with evidence-based teaching frameworks shown to promote learning in the operating room (OR). We hypothesize that participating faculty will deliver improved instruction as perceived by residents. METHODS: Residents anonymously rated faculty teaching behaviors among whom they had recently worked in the OR (minimum 3 cases in preceding 6 months) using the Briefing - Intraoperative teaching - Debriefing Assessment Tool (BIDAT; 1 = never, 5 = always)...
August 16, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28817305/foot-massage-touch-and-presence-in-decreasing-anxiety-during-a-magnetic-resonance-imaging-a-feasibility-study
#4
Rajni Parmar, Barbara B Brewer, Laura A Szalacha
OBJECTIVES: The purpose of the study was to determine (1) recruitment feasibility; (2) intervention adherence; (3) intervention acceptability; and (4) the preliminary effects of touch or foot massage interventions on anxiety during a magnetic resonance imaging (MRI). DESIGN: A quasi-experimental design was used. INTERVENTION: Foot massage and touch were the intervention groups and "presence" was the control group. SETTING: The study was conducted at the Center for Neurosciences, a freestanding facility, in southern Arizona...
August 17, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28817223/single-dose-euglycemic-clamp-studies-demonstrating-pharmacokinetic-and-pharmacodynamic-similarity-between-mk-1293-insulin-glargine-and-originator-insulin-glargine-lantus-in-type-1-diabetes-and-healthy-subjects
#5
Michael Crutchlow, John S Palcza, Kate M Mostoller, Chantal D Mahon, April M Barbour, Michael C Marcos, Yang Xu, Elaine Watkins, Linda Morrow, Marcus Hompesch
AIMS: MK-1293 is an insulin glargine that has an identical amino acid sequence to that of Lantus, the originator insulin glargine. Two euglycemic clamp studies, one in subjects with Type 1 diabetes (T1D) and one in healthy subjects, were conducted to demonstrate pharmacokinetic (PK) and pharmacodynamic (PD) similarity between MK-1293 and Lantus commercially procured in both the European Union (EU-Lantus) and United States (US-Lantus). MATERIALS AND METHODS: Both studies were single-dose, randomized, double-blind, single-center, crossover studies with ≥7 days between dosing periods...
August 17, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28817195/vertical-off-centering-affects-organ-dose-in-chest-ct-evidence-from-monte-carlo-simulations-in-anthropomorphic-phantoms
#6
Natalia Saltybaeva, Hatem Alkadhi
PURPOSE: The objective of our study was to assess the effect of patient vertical off-centering on organ dose in chest CT with tube current modulation. METHODS: For this purpose, anthropomorphic phantoms representing adult male, female and overweight male were scanned on 192-slice CT scanner at eleven different vertical positions (maximal off-centering ± 5 cm). Monte Carlo simulations were performed for each of the investigated setup, using tube current values extracted from the raw data, in order to obtain 3D dose distributions...
August 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28817182/centralized-patient-reported-outcome-data-collection-in-transplantation-is-feasible-and-clinically-meaningful
#7
Bronwen E Shaw, Ruta Brazauskas, Heather R Millard, Rachel Fonstad, Kathryn E Flynn, Amy Abernethy, Jenny Vogel, Charney Petroske, Deborah Mattila, Rebecca Drexler, Stephanie J Lee, Mary M Horowitz, J Douglas Rizzo
BACKGROUND: Allogeneic hematopoietic cell transplantation (HCT) cures many patients, but often with the risk of late effects and impaired quality of life. The value of quantifying patient-reported outcomes (PROs) is increasingly being recognized, but the routine collection of PROs is uncommon. This study evaluated the feasibility of prospective PRO collection by an outcome registry at multiple time points from unselected HCT patients undergoing transplantation at centers contributing clinical data to the Center for International Blood and Marrow Transplant Research (CIBMTR), and then it correlated the PRO data with clinical and demographic data...
August 17, 2017: Cancer
https://www.readbyqxmd.com/read/28817180/preventable-and-mitigable-adverse-events-in-cancer-care-measuring-risk-and-harm-across-the-continuum
#8
Allison Lipitz-Snyderman, David Pfister, David Classen, Coral L Atoria, Aileen Killen, Andrew S Epstein, Christopher Anderson, Elizabeth Fortier, Saul N Weingart
BACKGROUND: Patient safety is a critical concern in clinical oncology, but the ability to measure adverse events (AEs) across cancer care is limited by a narrow focus on treatment-related toxicities. The objective of this study was to assess the nature and extent of AEs among cancer patients across inpatient and outpatient settings. METHODS: This was a retrospective cohort study of 400 adult patients selected by stratified random sampling who had breast (n = 128), colorectal (n = 136), or lung cancer (n = 136) treated at a comprehensive cancer center in 2012...
August 17, 2017: Cancer
https://www.readbyqxmd.com/read/28817074/familial-resemblance-in-dietary-intakes-of-children-adolescents-and-parents-does-dietary-quality-play-a-role
#9
Leonie H Bogl, Karri Silventoinen, Antje Hebestreit, Timm Intemann, Garrath Williams, Nathalie Michels, Dénes Molnár, Angie S Page, Valeria Pala, Stalo Papoutsou, Iris Pigeot, Lucia A Reisch, Paola Russo, Toomas Veidebaum, Luis A Moreno, Lauren Lissner, Jaakko Kaprio
Information on familial resemblance is important for the design of effective family-based interventions. We aimed to quantify familial correlations and estimate the proportion of variation attributable to genetic and shared environmental effects (i.e., familiality) for dietary intake variables and determine whether they vary by generation, sex, dietary quality, or by the age of the children. The study sample consisted of 1435 families (1007 mothers, 438 fathers, 1035 daughters, and 1080 sons) from the multi-center I...
August 17, 2017: Nutrients
https://www.readbyqxmd.com/read/28816962/relationships-of-capsule-endoscopy-lewis-score-with-clinical-disease-activity-indices-c-reactive-protein-and-small-bowel-transit-time-in-pediatric-and-adult-patients-with-small-bowel-crohn-s-disease
#10
Chengcheng He, Jie Zhang, Zhenyu Chen, Xicheng Feng, Zibin Luo, Tianmo Wan, Aimin Li, Side Liu, Yuexin Ren
Relationships between the capsule endoscopy Lewis score (LS) and clinical disease activity indices and C-reactive protein (CRP) are controversial in adult patients with Crohn's disease (CD). Also, data on pediatric patients are relatively less. However, correlation between LS and small bowel transit time (SBTT) remains investigational. The aim of the present study was to explore the correlations between LS and clinical disease activity indices, CRP, SBTT in pediatric, and adult patients with small bowel CD...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28816915/physician-awareness-of-developmental-screening-and-referral-in-the-state-of-kuwait
#11
Hollie Hix-Small, Khaled Alkherainej
OBJECTIVE: In the State of Kuwait, family physicians and pediatricians are responsible for identifying and referring children at risk of disability. The aims of this study were to better understand physician (1) use of developmental screening instruments, (2) referral practices for children at risk of developmental disability, (3) interpretation of screening results, and (4) anticipatory guidance topics prioritized over child screening. METHODS: A nonprobability volunteer, self-selection sample of family physicians, general practitioners, and pediatricians (n = 398) completed a 60-item paper questionnaire...
August 9, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28816837/individualizing-thresholds-of-cerebral-perfusion-pressure-using-estimated-limits-of-autoregulation
#12
Joseph Donnelly, Marek Czosnyka, Hadie Adams, Chiara Robba, Luzius A Steiner, Danilo Cardim, Brenno Cabella, Xiuyun Liu, Ari Ercole, Peter John Hutchinson, David Krishna Menon, Marcel J H Aries, Peter Smielewski
OBJECTIVES: In severe traumatic brain injury, cerebral perfusion pressure management based on cerebrovascular pressure reactivity index has the potential to provide a personalized treatment target to improve patient outcomes. So far, the methods have focused on identifying "one" autoregulation-guided cerebral perfusion pressure target-called "cerebral perfusion pressure optimal". We investigated whether a cerebral perfusion pressure autoregulation range-which uses a continuous estimation of the "lower" and "upper" cerebral perfusion pressure limits of cerebrovascular pressure autoregulation (assessed with pressure reactivity index)-has prognostic value...
September 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28816541/variability-in-thyroid-cancer-management-and-prognosis-among-hispanic-versus-non-hispanic-patients-17-years-data-from-university-of-texas-health-science-center-and-university-health-system-at-san-antonio
#13
Sara Ahmadi, Carol Ramirez Rojas, Maria Luisa Policarpio-Nicolas, Darlene Metter, Diane Avery, Thomas J Prihoda, Mona M Sabra
Abstracts: Objective : Given the increase in the incidence of thyroid cancer in the United States, and it's potential public health implications, patient studies assessing ethnic, disparity and health care access are important. In this study, we retrospectively examined the variability in stage of thyroid cancer at presentation and final outcome among Hispanic vs non-Hispanic patients. METHOD: After obtaining IRB approval, we retrospectively reviewed the medical records of 220 adult patients with papillary thyroid carcinoma(PTC) who were treated at UT Health Science Center San Antonio between1996 and 2013...
August 17, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28816276/-percutaneous-biopsy-of-the-renal-masses-under-ultrasound-a-single-center-14-years-experience
#14
Y X Zhang, X B Meng, L Yao, C J Zhang, G Song, L Cai, Z Zhang, X S Li, K Gong, S Q Li, G Z Shan, Q He, X Y Yang, Z S He, L Q Zhou
OBJECTIVE: To assess the diagnostic rate, safety and clinical application of percutaneous renal masses biopsy for advanced renal cell carcinoma patients. METHODS: In this retrospective study, we collected the data of renal masses from the patients who underwent renal masses biopsy under ultrasound from April 2001 to December 2014 in Peking University First Hospital. A total of 75 patients who were undiagnosed or diagnosed with advanced renal cell carcinoma by the imageological method were enrolled in this study...
August 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28816194/risk-factors-associated-with-dental-implant-failure-a-study-of-302-implants-placed-in-a-regional-center
#15
Mehmet Oztel, Wojciech M Bilski, Arthur Bilski
AIM: The aim of this research is to determine which risk factors are associated with dental implant failure and survival. MATERIALS AND METHODS: Data pertaining to patients who received one or more dental implants from 2011 to 2013 in a regional center were retrospectively reviewed. This included a total of 302 Biomet 3i NanoTite Tapered Certain implants placed in 177 patients. All patients were followed up until the end of 2015. RESULTS: This study found an overall success rate of 95%...
August 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28816058/tscc-and-tscyc-screening-forms-in-a-clinical-sample-reliability-validity-and-creating-local-clinical-norms
#16
Jeffrey N Wherry, Catherine E Dunlop
Clinical norms were developed for two screening tools recently developed by Briere and published by Psychological Assessment Resources. The screening measures were derived from the most predictive items of the Trauma Symptom Checklist for Children (TSCC) and the Trauma Symptom Checklist for Young Children (TSCYC). Both screening measures (TSCC-Screening Form and TSCYC-Screening Form) have a total of 20 items measuring general trauma (12 items) and sexual concerns (8 items). Briere and Wherry report on the reliability and validity of the instrument when used with a normative group of children who are not identified as abused...
January 1, 2017: Child Maltreatment
https://www.readbyqxmd.com/read/28816053/in-vitro-exposure-systems-and-dosimetry-assessment-tools-for-inhaled-tobacco-products-workshop-proceedings-conclusions-and-paths-forward-for-in-vitro-model-use
#17
Holger Behrsing, Erin Hill, Hans Raabe, Raymond Tice, Suzanne Fitzpatrick, Robert Devlin, Kent Pinkerton, Günter Oberdörster, Chris Wright, Roman Wieczorek, Michaela Aufderheide, Sandro Steiner, Tobias Krebs, Bahman Asgharian, Richard Corley, Michael Oldham, Jason Adamson, Xiang Li, Irfan Rahman, Sonia Grego, Pei-Hsuan Chu, Shaun McCullough, Rodger Curren
In 2009, the passing of the Family Smoking Prevention and Tobacco Control Act facilitated the establishment of the FDA Center for Tobacco Products (CTP), and gave it regulatory authority over the marketing, manufacture and distribution of tobacco products, including those termed 'modified risk'. On 4-6 April 2016, the Institute for In Vitro Sciences, Inc. (IIVS) convened a workshop conference entitled, In Vitro Exposure Systems and Dosimetry Assessment Tools for Inhaled Tobacco Products, to bring together stakeholders representing regulatory agencies, academia and industry to address the research priorities articulated by the FDA CTP...
July 2017: Alternatives to Laboratory Animals: ATLA
https://www.readbyqxmd.com/read/28815699/application-of-the-condensed-protocol-for-the-nia-aa-guidelines-for-the-neuropathologic-assessment-of-alzheimer-s-disease-in-an-academic-clinical-practice
#18
Rajnish Bharadwaj, Patrick J Cimino, Margaret E Flanagan, Caitlin S Latimer, Luis F Gonzalez-Cuyar, Gordana Juric-Sekhar, Thomas J Montine, Desiree A Marshall, C Dirk Keene
AIMS: In response to concerns regarding resource expenditures required to fully implement the 2012 NIA-AA Sponsored Guidelines for the neuropathologic assessment of Alzheimer's disease (AD), we previously developed a sensitive and cost-reducing Condensed Protocol (CP) at the University of Washington (UW) Alzheimer's Disease Research Center (ADRC) that consolidated the recommended NIA-AA protocol into fewer cassettes requiring fewer immunohistochemical stains. The CP was not designed to replace NIA-AA protocols, but instead to make the NIA-AA criteria accessible to clinical and forensic neuropathology practices where resources limit full implementation of NIA-AA guidelines...
August 16, 2017: Histopathology
https://www.readbyqxmd.com/read/28815564/target-temperature-34-vs-36%C3%A2-c-after-out-of-hospital-cardiac-arrest-a-retrospective-observational-study
#19
L Arvidsson, S Lindgren, L Martinell, S Lundin, C Rylander
BACKGROUND: Intensive care for comatose survivors of cardiac arrest includes targeted temperature management (TTM) to attenuate cerebral reperfusion injury. A recent multi-center clinical trial did not show any difference in mortality or neurological outcome between TTM targeting 33°C or 36°C after out-of-hospital-cardiac-arrest (OHCA). In our institution, the TTM target was changed accordingly from 34 to 36°C. The aim of this retrospective study was to analyze if this change had affected patient outcome...
August 16, 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28815414/comparison-of-image-quality-between-step-and-shoot-and-continuous-bed-motion-techniques-in-whole-body-18-f-fluorodeoxyglucose-positron-emission-tomography-with-the-same-acquisition-duration
#20
Shozo Yamashita, Haruki Yamamoto, Tetsu Nakaichi, Tatsuya Yoneyama, Kunihiko Yokoyama
OBJECTIVE: This study aimed to compare the qualities of whole-body positron emission tomography (PET) images acquired by the step-and-shoot (SS) and continuous bed motion (CBM) techniques with approximately the same acquisition duration, through phantom and clinical studies. METHODS: A body phantom with 10-37 mm spheres was filled with (18)F-fluorodeoxyglucose (FDG) solution at a sphere-to-background radioactivity ratio of 4:1 and acquired by both techniques. Reconstructed images were evaluated by visual assessment, percentages of contrast (%Q H) and background variability (%N) in accordance with the Japanese guideline for oncology FDG-PET/computed tomography (CT)...
August 16, 2017: Annals of Nuclear Medicine
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