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https://www.readbyqxmd.com/read/29049712/easy-technique-for-emergency-fenestration-in-non-fenestrated-fontan-patients
#1
Qiang Fan, Yunfei Ling, Yabo Wang, Qi An
The Fontan procedure is a commonly used final pathway of palliation for single-ventricle physiology. Performing it without fenestration can avoid fenestration-related drawbacks, including subnormal oxygen saturation, decreased exercise tolerance, paradoxical embolization and subsequent need for closure by catheter intervention. If emergency fenestration is required, however, it is not always technically easy to perform, particularly when the atrium is posteriorly located and difficult to expose. We describe an easy technique for creating an anastomosis using a ring-supported polytetrafluoroethylene graft to the atrium for fenestration, performed in 2 patients who underwent extracardiac conduit Fontan procedures without fenestration...
July 13, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29044337/beneficial-effects-of-intradialytic-cardiopulmonary-rehabilitation
#2
Bruno Medeiros Guio, Carlos Perez Gomes, Fabio Brandão da Costa, Adriana Dos Santos de Oliveira, Marta Turano Duarte, Maurilo Leite
INTRODUCTION: Patients on hemodialysis (HD) present high mortality from cardiovascular complications and high morbidity, including decreasing functional capacity and quality of life. OBJECTIVE: To analyze clinical and laboratory responses of patients in HD to intradialytic cardiopulmonary rehabilitation on an outpatient basis. METHODS: We evaluated 14 patients in a prospective study for 8 months using cardiopulmonary rehabilitation protocol (CRehab) consisted of intradialytic aerobic exercise with a cycle ergometer...
July 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29042272/effect-of-dietary-nitrate-on-respiratory-physiology-at-high-altitude-results-from-the-xtreme-alps-study
#3
Andrew Cumpstey, Philip J Hennis, Edward T Gilbert-Kawai, Bernadette O Fernandez, Matthieu Poudevigne, Alexandra Cobb, Paula Meale, Kay Mitchell, Helen Moyses, Helmut Pöhnl, Monty G Mythen, Michael P W Grocott, Martin Feelisch, Daniel S Martin
Nitric oxide (NO) production plays a central role in conferring tolerance to hypoxia. Tibetan highlanders, successful high-altitude dwellers for millennia, have higher circulating nitrate and exhaled NO (ENO) levels than native lowlanders. Since nitrate itself can reduce the oxygen cost of exercise in normoxia it may confer additional benefits at high altitude. Xtreme Alps was a double-blinded randomised placebo-controlled trial to investigate how dietary nitrate supplementation affects physiological responses to hypoxia in 28 healthy adult volunteers resident at 4559 m for 1 week; 14 receiving a beetroot-based high-nitrate supplement and 14 receiving a low-nitrate 'placebo' of matching appearance/taste...
October 14, 2017: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/29038746/influence-of-exercise-duration-on-cardiorespiratory-responses-energy-cost-and-tissue-oxygenation-within-a-6-hour-treadmill-run
#4
Hugo A Kerhervé, Scott McLean, Karen Birkenhead, David Parr, Colin Solomon
PURPOSE: The physiological mechanisms for alterations in oxygen utilization ([Formula: see text]) and the energy cost of running (Cr ) during prolonged running are not completely understood, and could be linked with alterations in muscle and cerebral tissue oxygenation. METHODS: Eight trained ultramarathon runners (three women; mean ± SD; age 37 ± 7 yr; maximum [Formula: see text] 60 ± 15 mL min(-1) kg(-1)) completed a 6 hr treadmill run (6TR), which consisted of four modules, including periods of moderate (3 min at 10 km h(-1), 10-CR) and heavy exercise intensities (6 min at 70% of maximum [Formula: see text], HILL), separated by three, 100 min periods of self-paced running (SP)...
2017: PeerJ
https://www.readbyqxmd.com/read/29035586/hemoconcentration-during-maximum-exercise-in-miners-with-chronic-intermittent-exposure-to-hypobaric-hypoxia-3800%C3%A2-m
#5
Fernando A Moraga, Jorge Osorio, Rodrigo Calderón-Jofré, Andrés Pedreros
Moraga, Fernando A., Jorge Osorio, Rodrigo Calderón-Jofré, and Andrés Pedreros. Hemoconcentration during maximum exercise in miners with chronic intermittent exposure to hypobaric hypoxia (3800 m). High Alt Med Biol. 16:000-000, 2017. OBJECTIVE: To evaluate the effect of maximum exercise on hemoconcentration in miners with chronic intermittent hypobaric hypoxia (CIHH) at 3800 m. MATERIALS AND METHODS: Sixteen miners with CIHH at high altitude (3800 m) were subjected to maximum exercise levels on a cycle ergometer, increasing exercise load by 50 W every 3 minutes at sea level and high altitude (3800 m)...
October 16, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29032393/acute-effects-of-repeated-cycling-sprints-in-hypoxia-induced-by-voluntary-hypoventilation
#6
Xavier Woorons, Patrick Mucci, Julien Aucouturier, Agathe Anthierens, Grégoire P Millet
PURPOSE: This study aimed to investigate the acute responses to repeated-sprint exercise (RSE) in hypoxia induced by voluntary hypoventilation at low lung volume (VHL). METHODS: Nine well-trained subjects performed two sets of eight 6-s sprints on a cycle ergometer followed by 24 s of inactive recovery. RSE was randomly carried out either with normal breathing (RSN) or with VHL (RSH-VHL). Peak (PPO) and mean power output (MPO) of each sprint were measured. Arterial oxygen saturation, heart rate (HR), gas exchange and muscle concentrations of oxy-([O2Hb]) and deoxyhaemoglobin/myoglobin ([HHb]) were continuously recorded throughout exercise...
October 14, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29024041/strength-training-improves-double-poling-performance-after-prolonged-submaximal-exercise-in-cross-country-skiers
#7
S Øfsteng, Ø Sandbakk, M van Beekvelt, D Hammarström, R Kristoffersen, J Hansen, G Paulsen, B R Rønnestad
The purpose of this study was to investigate the effects of adding strength training with or without vibration to cross-country (XC) skiers' endurance training on double poling (DP) performance, physiological and kinematic adaptations. Twenty-one well-trained male XC skiers combined endurance- and upper-body strength-training three times per week, either with (n=11) or without (n=10) superimposed vibrations for 8 weeks, whereas eight skiers performed endurance training only (CON). Testing included 1RM in upper-body exercises, work economy, neural activation, oxygen saturation in muscle and DP kinematics during a prolonged submaximal DP roller ski test which was directly followed by a time to exhaustion (TTE) test...
October 10, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28984368/autogenic-drainage-for-airway-clearance-in-cystic-fibrosis
#8
REVIEW
Pamela McCormack, Paul Burnham, Kevin W Southern
BACKGROUND: Autogenic drainage is an airway clearance technique that was developed by Jean Chevaillier in 1967. The technique is characterised by breathing control using expiratory airflow to mobilise secretions from smaller to larger airways. Secretions are cleared independently by adjusting the depth and speed of respiration in a sequence of controlled breathing techniques during exhalation. The technique requires training, concentration and effort from the individual. It is important to systematically review the evidence demonstrating that autogenic drainage is an effective intervention for people with cystic fibrosis...
October 6, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28975517/the-effects-of-hyperoxia-on-sea-level-exercise-performance-training-and-recovery-a-meta-analysis
#9
REVIEW
Matthew M Mallette, Desmond G Stewart, Stephen S Cheung
BACKGROUND: Acute exercise performance can be limited by arterial hypoxemia, such that hyperoxia may be an ergogenic aid by increasing tissue oxygen availability. Hyperoxia during a single bout of exercise performance has been examined using many test modalities, including time trials (TTs), time to exhaustion (TTE), graded exercise tests (GXTs), and dynamic muscle function tests. Hyperoxia has also been used as a long-term training stimulus or a recovery intervention between bouts of exercise...
October 3, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28969859/effects-of-acute-use-of-pursed-lips-breathing-during-exercise-in-patients-with-copd-a-systematic-review-and-meta-analysis
#10
REVIEW
Anamaria Fleig Mayer, Manuela Karloh, Karoliny Dos Santos, Cintia Laura Pereira de Araujo, Aline Almeida Gulart
BACKGROUND: Pursed-lips breathing (PLB) is a ventilatory strategy frequently adopted spontaneously by patients with chronic obstructive pulmonary disease (COPD) to relieve dyspnoea, and its practice is widely taught as a respiratory strategy to increase exercise tolerance. OBJECTIVE: To investigate the effects of acute use of PLB in exercise performance, dyspnoea, ventilatory parameters and oxygen saturation during exercise in patients with COPD. DATA SOURCES: PEDro, EMBASE, MEDLINE via OVID, and EBSCO up to May 2016...
August 31, 2017: Physiotherapy
https://www.readbyqxmd.com/read/28966706/the-effect-of-psychomotor-performance-cerebral-and-arterial-blood-saturation-between-african-american-and-caucasian-males-before-during-and-after-normobaric-hypoxic-exercise
#11
Matthew R Feeback, Yongsuk Seo, Matthew Dancy, Ellen L Glickman
To further elucidate physiological and cognitive performance differences between African-American (AA) and Caucasian individuals (CAU) before, during or after hypoxic and normoxic exercise. Twelve college aged (18-25) apparently healthy African-American (six volunteers) and Caucasian (six subjects) males took part in two trials consisting of normobaric normoxia and normobaric hypoxia (12% oxygen). Each subject cycled at 50% of their altitude adjusted VO2max (-26% of normoxia VO2max) for one hour after a two-hour baseline...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/28966315/prognostic-value-of-pulmonary-artery-compliance-in-patients-with-pulmonary-arterial-hypertension-associated-with-adult-congenital-heart-disease
#12
Xiao-Ling Cheng, Zhi-Hong Liu, Qing Gu, Xin-Hai Ni, Qin Luo, Zhi-Hui Zhao, Jian-Guo He, Chang-Ming Xiong
In congenital heart disease (CHD), the presence of pulmonary arterial hypertension (PAH) is associated with a poor prognosis. In this study, we aim to investigate the role of pulmonary artery compliance (Cp) in predicting the mortality of PAH associated with adult congenital heart disease (APAH-CHD). One-hundred and seventy-five patients ofAPAH-CHD who underwent a comprehensive clinical evaluation were included in this study. All patients were followed up in a 6-month interval and the primary end point was all cause of death...
September 30, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28960914/cpap-and-epap-elicit-similar-lung-deflation-in-a-non-equivalent-mode-in-gold-3-4-copd-patients
#13
Paulo de Tarso Müller, Gustavo Christofoletti, Rodrigo Koch, João Henrique Zardetti Nogueira, Luiz Armando Pereira Patusco, Gaspar Rogério Chiappa
Introduction Lung hyperinflation is associated with inspiratory muscle strength reduction, nocturnal desaturation, dyspnea, altered cardiac function and poor exercise capacity in advanced COPD. Objectives We investigated the responses of inspiratory capacity (IC) and inspiratory muscle strength (PImax), comparing continuous positive airway pressure (CPAP) and expiratory positive airway pressure (EPAP) with the main hypothesis that there would be similar effects on lung deflation. Methods Eligible patients were submitted to 10 cmH2 O CPAP and EPAP on different days, under careful ECG (HR) and peripheral oxygen saturation (SpO2 ) monitoring...
September 28, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28959210/in-vivo-assessment-of-mitochondrial-dysfunction-in-clinical-populations-using-near-infrared-spectroscopy
#14
REVIEW
T Bradley Willingham, Kevin K McCully
The ability to sustain submaximal exercise is largely dependent on the oxidative capacity of mitochondria within skeletal muscle, and impairments in oxidative metabolism have been implicated in many neurologic and cardiovascular pathologies. Here we review studies which have demonstrated the utility of Near-infrared spectroscopy (NIRS) as a method of evaluating of skeletal muscle mitochondrial dysfunction in clinical human populations. NIRS has been previously used to noninvasively measure tissue oxygen saturation, but recent studies have demonstrated the utility of NIRS as a method of evaluating skeletal muscle oxidative capacity using post-exercise recovery kinetics of oxygen metabolism...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28954015/changes-on-physiological-parameters-of-tambaqui-colossoma-macropomum-fed-with-diets-supplemented-with-amazonian-fruit-camu-camu-myrciaria-dubia
#15
P H R Aride, A M Oliveira, R B Batista, M S Ferreira, J Pantoja-Lima, D S Ladislau, P D S Castro, A T Oliveira
The physiological responses of juvenile tambaqui (Colossoma macropomum) fed commercial feed supplemented with different concentrations of camu camu (Myrciaria dubia) were evaluated. The design was completely randomized, with treatments arranged in a factorial design with three proportions of camu camu (15%, 30% and 45%) and a control treatment (100% commercial diet), with four replicates per treatment. A total of 96 tambaqui specimens were used, with a mean initial weight of 11.69 ± 2.68 g and a mean length of 7...
September 21, 2017: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/28924565/nirs-based-cerebrovascular-regulation-assessment-exercise-and-cerebrovascular-reactivity
#16
Stephanie Miller, Kunal Mitra
Alterations to cerebral blood flow (CBF) have been implicated in diverse neurological conditions. Near-infrared spectroscopy (NIRS)-measured regional cerebral tissue oxygen saturation ([Formula: see text]) provides an estimate of oxygenation of interrogated cerebral volume useful in identifying variations in oxygen supply to cerebral tissue and in monitoring cerebrovascular function. [Formula: see text]-inhalation-based hypercapnic breathing challenges were used to simulate CBF dysregulation, utilizing NIRS to monitor the CBF autoregulatory response...
October 2017: Neurophotonics
https://www.readbyqxmd.com/read/28922681/exercise-training-protects-cardiomyocytes-from-deleterious-effects-of-palmitate
#17
Marcia Netto Magalhães Alves, Danilo Roman-Campos, Amanda B Parreira, Pedro W M Almeida, Jader Santos Cruz, Silvia Guatimosim, Marco Fabricio Dias-Peixoto
We investigated the effects of palmitate, a high saturated fat, on Ca(2+), action potential and reactive oxygen species dynamics in cardiomyocytes from untrained and trained mice. Male mice were subjected to moderate intensity exercise training on a treadmill. Cardiomyocytes of untrained and trained mice were isolated, treated for 30 min with palmitate and intracellular calcium transient and action potential duration were recorded. Additionally, we assessed reactive oxygen species generation. Treatment of cardiomyocytes from untrained mice with palmitate induced a significant decrease in Ca(2+) transient magnitude by 34%...
September 18, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28911936/exercise-training-in-patients-with-pulmonary-and-systemic-hypertension-a-unique-therapy-for-two-different-diseases
#18
REVIEW
Massimo Leggio, Augusto Fusco, Giorgio Limongelli, Luca Sgorbini
Pulmonary hypertension is a potentially life-threatening condition. Given its evolving definition, the incidence and prevalence of the disease is difficult to define, but registries suggest an increased global awareness. The management of patients with pulmonary arterial hypertension is highly specialised and requires multi-disciplinary input from a range of healthcare professionals, including cardiologists, respiratory physicians, rheumatologists, rehabilitation physicians and cardio-pulmonary physiotherapists...
September 11, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28887041/partial-anomalous-pulmonary-venous-connection-in-a-dog
#19
Chloe L Thorn, Naomi R Ford, Meg M Sleeper
A 2-year-old male intact Belgian Malinois was presented for exercise intolerance. A grade III/VI left basilar systolic murmur was detected. Echocardiography revealed moderate right atrial and ventricular dilation and increased pulmonic outflow velocity. Thoracic radiographs showed right heart enlargement and a dilated caudal vena cava. In addition, on the left lateral projection, an enlarged aberrant right cranial pulmonary lobar vein was suspected to be diverging ventrally from the course of the right cranial lobar bronchus and inserting more ventrally than normal in the region of the right atrium...
September 5, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28878483/factors-affecting-dyspnea-after-the-6-minute-walk-test-in-idiopathic-pulmonary-fibrosis-patients-presenting-with-exercise-induced-hypoxemia
#20
Akira Morino, Hiroki Takahashi, Hirofumi Chiba, Sumio Ishiai
[Purpose] The current study aimed to investigate factors affecting dyspnea after the 6-minute walk test (6MWT) in idiopathic pulmonary fibrosis (IPF) patients presenting with hypoxemia. [Subjects and Methods] The subjects were IPF out-patients with stable symptoms whose percutaneous arterial oxygen saturation fell to 88% during the 6MWT test. Quadriceps force, 6-minute walk distance (6MWD), dyspnea after the 6MWT, and leg fatigue (LF) were evaluated as exercise-related variables. [Results] The subjects were 14 patients (mean age 73...
August 2017: Journal of Physical Therapy Science
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