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oxygen saturation exercise

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Background Long-term treatment with supplemental oxygen has unknown efficacy in patients with stable chronic obstructive pulmonary disease (COPD) and resting or exercise-induced moderate desaturation. Methods We originally designed the trial to test whether long-term treatment with supplemental oxygen would result in a longer time to death than no use of supplemental oxygen among patients who had stable COPD with moderate resting desaturation (oxyhemoglobin saturation as measured by pulse oximetry [Spo2], 89 to 93%)...
October 27, 2016: New England Journal of Medicine
Toshiyuki Ohya, Ryo Yamanaka, Hayato Ohnuma, Masahiro Hagiwara, Yasuhiro Suzuki
BACKGROUND: Some endurance athletes exhibit exercise-induced arterial hypoxemia during high-intensity exercise. Inhalation of hyperoxic gas during exercise has been shown to counteract this exercise-associated reduction in hemoglobin oxygen saturation (SaO2), but the effects of hyperoxic gas inhalation on performance and SaO2 during high-intensity intermittent exercise remain unclear. This study investigated the effects of hyperoxic gas inhalation on performance and SaO2 during high-intensity intermittent cycling exercise...
December 2016: Sports Medicine—Open
Konstantina Dipla, Areti Triantafyllou, Iris Grigoriadou, Evangelia Kintiraki, Georgios A Triantafyllou, Pavlos Poulios, Ioannis S Vrabas, Andreas Zafeiridis, Stella Douma, Dimitrios G Goulis
AIMS/HYPOTHESIS: Gestational diabetes mellitus (GDM) is a risk factor for the development of endothelial dysfunction and cardiovascular disease. However, in vivo microvascular endothelial function in GDM has not been investigated. This study aimed to examine, using near-infrared spectroscopy (NIRS), whether: (1) there are differences in microvascular reactivity and skeletal muscle oxygen consumption (m[Formula: see text]) at rest and during exercise between GDM and uncomplicated pregnancies; and (2) there is an association of NIRS indices with macrovascular function and cardiovascular disease risk factors...
October 8, 2016: Diabetologia
Jianxiong Shen, Youxi Lin, Jinmei Luo, Yi Xiao
BACKGROUND: Scoliosis causes impairment of the respiratory and cardiovascular systems. Traditional pulmonary function tests only examine patients under static conditions. The aim of our study was to investigate the correlation between radiographic parameters and dynamic cardiopulmonary capacity in patients with idiopathic scoliosis. METHODS: Forty patients with idiopathic scoliosis were included in this prospective study from January 2014 to February 2016. The patients underwent full radiographic assessment of deformity, pulmonary function testing, and cardiopulmonary bicycle ergometer testing...
October 5, 2016: Journal of Bone and Joint Surgery. American Volume
Richard B Thompson, Joseph J Pagano, Kory W Mathewson, Ian Paterson, Jason R Dyck, Dalane W Kitzman, Mark J Haykowsky
The goals of the current study were to compare leg blood flow, oxygen extraction and oxygen uptake (VO2) after constant load sub-maximal unilateral knee extension (ULKE) exercise in patients with heart failure with reduced ejection fraction (HFrEF) compared to those with preserved ejection fraction (HFpEF). Previously, it has been shown that prolonged whole body VO2 recovery kinetics are directly related to disease severity and all-cause mortality in HFrEF patients. To date, no study has simultaneously measured muscle-specific blood flow and oxygen extraction post exercise recovery kinetics in HFrEF or HFpEF patients; therefore it is unknown if muscle VO2 recovery kinetics, and more specifically, the recovery kinetics of blood flow and oxygen extraction at the level of the muscle, differ between HF phenotypes...
2016: PloS One
Valérie Julian, David Thivel, Bruno Pereira, Frédéric Costes, Ruddy Richard, Martine Duclos
OBJECTIVE: The effects of a training program (TP) on muscle microvascularization during exercise remained to be explored in adolescents with obesity. We hypothesized that a TP would lead to better microvascular adaptations to exercise in skeletal muscle. METHODS: 15 inactive adolescents followed a 12-week TP where both peripheral (muscular microvascularization) and central (cardiac) adaptations to exercise (40 min exercise set at 70% V̇O2peak) were assessed before and after intervention...
October 4, 2016: Obesity Facts
Vasileios Andrianopoulos, Bartolome R Celli, Frits M E Franssen, Victor M Pinto-Plata, Peter M A Calverley, Lowie E G W Vanfleteren, Ioannis Vogiatzis, Jørgen Vestbo, Alvar Agusti, Per S Bakke, Stephen I Rennard, William MacNee, Ruth Tal-Singer, Julie C Yates, Emiel F M Wouters, Martijn A Spruit
Exercise-induced oxygen desaturation (EID) is related to mortality in patients with chronic obstructive pulmonary disease (COPD). We investigated: (1) the prevalence of EID; (2) the relative-weight of several physiological determinants of EID including pulmonary emphysema, and (3) the relationship of EID with certain patients' clinical characteristics. Data from 2050 COPD patients (age: 63.3 ± 7.1years; FEV1: 48.7 ± 15.7%pred.) were analyzed. The occurrence of EID (SpO2post ≤88%) at the six-minute walking test (6MWT) was investigated in association with emphysema quantified by computed-tomography (QCT), and several clinical characteristics...
October 2016: Respiratory Medicine
Brendan R Scott, Katie M Slattery, Dean V Sculley, Catriona Lockhart, Ben J Dascombe
This study assessed whether hypoxia augments anabolic responses to moderate-load resistance exercise. Fourteen trained males performed moderate-load resistance exercise in normoxia (NORM; fraction of inspired oxygen [FIO2] = 21%) and moderate-level hypoxia (MH; FIO2 = 16%). Exercise comprised 3 sets of 10 repetitions of squats and deadlifts at 60% of 1-repetition maximum, with 60 s inter-set rest. Blood lactate (BLa) was quantified after each exercise, while arterial oxygen saturation (SpO2) and heart rate (HR) were assessed following each set...
September 20, 2016: Journal of Strength and Conditioning Research
Igor Cigarroa, Rodrigo Barriga, Camila Michéas, Rafael Zapata-Lamana, Claudio Soto, Tomas Manukian
BACKGROUND: Exercise may be a therapeutic tool for improving the functional capacity in patients with chronic kidney disease (CKD) who are on hemodialysis (HD). AIM: To determine the effects on muscle strength (MS), functional capacity (FC) and quality of life related to health (QOLRH) of a resistance training program in patients with CKD on HD. PATIENTS AND METHODS: Thirteen CKD patients aged 38.8 ± 3 years, (7 men) on HD for more than one year participated in an exercise program twice a week during 8 weeks...
July 2016: Revista Médica de Chile
Piotr Niewinski, Dariusz Janczak, Artur Rucinski, Stanislaw Tubek, Zoar J Engelman, Pawel Piesiak, Przemyslaw Jazwiec, Waldemar Banasiak, Marat Fudim, Paul A Sobotka, Shahrokh Javaheri, Emma C J Hart, Julian F R Paton, Piotr Ponikowski
AIMS: Augmented reflex responses from peripheral chemoreceptors, which are mainly localized in the carotid bodies (CBs), characterize patients with systolic heart failure and contribute to adrenergic hyperactivation. We investigated whether surgical resection of CBs in these patients can be performed safely to decrease sympathetic tone. METHODS AND RESULTS: We studied 10 male patients with systolic heart failure (age, 59 ± 3 years; LVEF, 27 ± 7%) who underwent unilateral right-sided CB resection (four patients) or bilateral CB resection (six patients)...
September 20, 2016: European Journal of Heart Failure
Erica J Roelofs, Abbie E Smith-Ryan, Eric T Trexler, Katie R Hirsch, Meredith G Mock
The effects of pomegranate extract (PE) supplementation were evaluated on high-intensity exercise performance, blood flow, vessel diameter, oxygen saturation (SPO2), heart rate (HR), and blood pressure (BP). In a randomized, crossover design, nineteen recreationally resistance-trained participants were randomly assigned to PE (1000 mg) or placebo (PL), which were consumed 30 min prior to a repeated sprint ability (RSA) test and repetitions to fatigue (RTF) on bench and leg press. The RSA consisted of ten six-second sprints on a friction-loaded cycle ergometer with 30 s recovery...
September 20, 2016: European Journal of Sport Science
Samuel Helfer, Joseph Quackenbush, Michael Fletcher, David R Pendergast
BACKGROUND: Climbing and trekking at altitude are common recreational and military activities. Physiological effects of altitude are hypoxia and hyperventilation. The hyperventilatory response to altitude may cause respiratory muscle fatigue and reduce sustained submaximal exercise. Voluntary isocapnic hyperpnea respiratory muscle training (VIHT) improves exercise endurance at sea level and at depth. The purpose of this study was to test the hypothesis that VIHT would improve exercise time at altitude [3600 m (11,811 ft)] compared to control and placebo groups...
August 2016: Aerospace Medicine and Human Performance
Dae-Hyouk Bang, Young-Lan Son
[Purpose] To investigate the effects of intensive aerobic exercise on respiratory capacity and walking ability in chronic stroke patients. [Subjects and Methods] The subjects were randomly assigned to an experimental group (n=6) or a control group (n=6). Patients in the experimental group received intensive aerobic exercise for 30 minutes and traditional physical therapy once a day, five days a week, for four weeks. The control group received aerobic exercise for 30 minutes and traditional physical therapy for 30 minutes a day, five days a week, for four weeks...
August 2016: Journal of Physical Therapy Science
Gidugu Himashree, Latika Mohan, Yogesh Singh
UNLABELLED: Context • High altitude (HA) is a psychophysiological stressor for natives of lower altitudes. Reducing the morbidity and optimizing the performance of individuals deployed in an HA region has been attempted and reported with varied results. Objective • The present study intended to explore the effects of comprehensive yogic practices on the health and performance of Indian soldiers deployed at HAs. Design • The research team designed a prospective, randomized, case-control study...
September 2016: Alternative Therapies in Health and Medicine
Philip J Hennis, Kay Mitchell, Edward Gilbert-Kawai, Vassiliki Bountziouka, Angie Wade, Martin Feelisch, Michael P Grocott, Daniel S Martin
: The purpose of this study was to investigate the effects of dietary nitrate supplementation, in the form of beetroot juice, on acute mountain sickness (AMS) symptoms and physiological responses, in a group of young males trekking to Mount Everest Base Camp (EBC). Forty healthy male students (mean age (SD): 16 (1) yrs) trekked to EBC over 11 days. Following an overnight fast, each morning participants completed the Lake Louise AMS questionnaire and underwent a series of physiological tests: resting blood pressure as well as resting and exercising heart rate, respiratory rate, and peripheral oxygen saturation...
September 2, 2016: Nitric Oxide: Biology and Chemistry
Anne-Fleur Gaston, Fabienne Durand, Emma Roca, Grégory Doucende, Ilona Hapkova, Enric Subirats
PURPOSE: The aim of this study was to investigate the impact of exercise-induced hypoxaemia (EIH) developed at sea-level on exercise responses at moderate acute altitude. METHODS: Twenty three subjects divided in three groups of individuals: highly trained with EIH (n = 7); highly trained without EIH (n = 8) and untrained participants (n = 8) performed two maximal incremental tests at sea-level and at 2,150 m. Haemoglobin O2 saturation (SpO2), heart rate, oxygen uptake (VO2) and several ventilatory parameters were measured continuously during the tests...
2016: PloS One
Serena Cirio, Manuela Piran, Michele Vitacca, Giancarlo Piaggi, Piero Ceriana, Matteo Prazzoli, Mara Paneroni, Annalisa Carlucci
INTRODUCTION: High flow nasal cannula (HFNC) was shown to washout the anatomical dead space, permitting a higher fraction of minute ventilation to participate in gas pulmonary exchanges. Moreover, it is able to guarantee the desired inhaled oxygen fraction (FiO2) even at high level of patient's minute ventilation by minimizing the room air entrainment. The effect of HFNC has never been investigated on stable severe COPD patients in term of endurance capacity with standardised laboratory tests...
September 2016: Respiratory Medicine
Jennifer Panosian, Su-Ann Ding, Marlene Wewalka, Donald C Simonson, Ann Goebel-Fabbri, Kathleen Foster, Florencia Halperin, Ashley Vernon, Allison B Goldfine
BACKGROUND: The purpose of this study was to compare effects of Roux-en-Y gastric bypass versus a multidisciplinary, group-based medical diabetes and weight management program on physical fitness and behaviors. METHODS: Physical behavior and fitness were assessed in participants of the study Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes (SLIMM-T2D) (NCT01073020), a randomized, parallel-group trial conducted at a US academic hospital and diabetes clinic with 18- to 24-month follow-up...
August 20, 2016: American Journal of Medicine
Oliver Michael Shannon, Lauren Duckworth, Matthew John Barlow, David Woods, Jose Lara, Mario Siervo, John Paul O'Hara
Nitrate-rich beetroot juice (BRJ) increases plasma nitrite concentrations, lowers the oxygen cost (V⋅O2) of steady-state exercise and improves exercise performance in sedentary and moderately-trained, but rarely in well-trained individuals exercising at sea-level. BRJ supplementation may be more effective in a hypoxic environment, where the reduction of nitrite into nitric oxide (NO) is potentiated, such that well-trained and less well-trained individuals may derive a similar ergogenic effect. We conducted a randomised, counterbalanced, double-blind placebo controlled trial to determine the effects of BRJ on treadmill running performance in moderate normobaric hypoxia (equivalent to 2500 m altitude) in participants with a range of aerobic fitness levels...
September 30, 2016: Nitric Oxide: Biology and Chemistry
Cristina Gonzalez-Millan, Dario Perez-Brunicardi, Juan Jose Salinero, Beatriz Lara, Javier Abián-Vicen, Francisco Areces, Diana Ruiz-Vicente, Lidon Soriano, Juan Del Coso
The aim of this study was to assess different physiological variables before and after a 5 km (women) and 10 km (men) cross-country skiing competition to determine potential mechanisms of fatigue. Fourteen elite-level skiers competed in an official cross-country skiing competition using the classical style (9 men and 5 women). Instantaneous skiing velocity was measured during the race by means of 15-Hz GPS devices. Before and after the race, a sample of venous blood was obtained to assess changes in blood lactate and serum electrolyte and myoglobin concentrations...
August 18, 2016: Journal of Strength and Conditioning Research
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