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https://www.readbyqxmd.com/read/28571677/brm-promoter-insertion-polymorphisms-increase-the-risk-of-cancer-a-meta-analysis
#1
REVIEW
Ouyang Xi, Xiao Long Ye, Hong Bo Wei
INTRODUCTION: Many studies have suggested that the BRM promoter insertion polymorphisms might be associated with susceptibility to many different types of cancer. However, previous studies reported contradictory results. This current meta-analysis was performed to address this issue. EVIDENCE ACQUISITION: A comprehensive search was conducted in multiple databases, including PubMed, Embase and China National Knowledge Infrastructure (CNKI). We collected relevant articles to explore the association between the BRM insertion polymorphisms and susceptibility of cancers...
May 29, 2017: Gene
https://www.readbyqxmd.com/read/28497594/the-impact-of-regulatory-action-on-the-co-prescribing-of-renin-angiotensin-system-blockers-in-uk-primary-care
#2
Craig Allen, Katherine Donegan
PURPOSE: The aim of this study was to assess the impact of regulatory action taken in June 2014 on the co-prescribing of renin-angiotensin system (RAS) blockers in UK primary care. METHODS: RAS blocker prescriptions, issued between 01/01/2009-30/06/2015, were extracted from the Clinical Practice Research Datalink to estimate the quarterly prevalence (number of patients with at least one co-prescription) and incidence (number of patients first receiving a RAS blocker co-prescription) of co-prescribing...
May 11, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28456547/visual-outcomes-following-bilateral-lmplantation-of-two-diffractive-trifocal-iols-in-10-084-eyes
#3
Rafael Bilbao-Calabuig, Andrea Llovet-Rausell, Julio Ortega-Usobiaga, Mercedes Martínez-Del-Pozo, Fernando Mayordomo-Cerdá, Celia Segura-Albentosa, Julio Baviera, Fernando Llovet-Osuna
PURPOSE: To investigate refractive and visual acuity outcomes, patient satisfaction and spectacle independence at three months of two diffractive (non-toric) trifocal IOLs in a large series of patients. DESIGN: Multicenter, retrospective, non-randomized clinical study. METHODS: Patients underwent lens phacoemulsification and were implanted bilaterally with a diffractive trifocal IOL: FineVision MicroF or AT Lisa tri 839MP. Surgeries were performed between 2011 and 2015 with at least 3 months of follow-up...
April 26, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28217856/molecular-characterization-of-a-new-gene-cluster-for-steroid-degradation-in-mycobacterium-smegmatis
#4
Lorena Fernández-Cabezón, Esther García-Fernández, Beatriz Galán, José L García
The C-19 steroids 4-androstene-3,17-dione (AD), 1,4-androstadiene-3,17-dione (ADD) or 9α-hydroxy-4-androstene-3,17-dione (9OH-AD), which have been postulated as intermediates of the cholesterol catabolic pathway in Mycobacterium smegmatis, cannot be used as sole carbon and energy sources by this bacterium. Only the ΔkstR mutant which constitutively expresses the genes repressed by the KstR regulator can metabolize AD and ADD with severe difficulties but still cannot metabolize 9OH-AD, suggesting that these compounds are not true intermediates but side products of the cholesterol pathway...
February 20, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28033521/physical-activity-and-sedentary-behavior-in-people-with-major-depressive-disorder-a-systematic-review-and-meta-analysis
#5
REVIEW
Felipe Schuch, Davy Vancampfort, Joseph Firth, Simon Rosenbaum, Philip Ward, Thaís Reichert, Natália Carvalho Bagatini, Roberta Bgeginski, Brendon Stubbs
BACKGROUND: Low levels of physical activity (PA) and sedentary behavior (SB) are independent risk factors for cardiovascular disease and premature mortality in people with major depressive disorder (MDD). AIMS: Investigate levels of PA and SB and their predictors in people with MDD. METHODS: Electronic databases were searched from inception till 04/2016 for articles measuring PA and SB with a self-report questionnaire (SRQ) or objective measure (e...
March 1, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28025574/intervention-related-increases-in-preoperative-physical-activity-are-maintained-6-months-after-bariatric-surgery-results-from-the-bari-active-trial
#6
D S Bond, J G Thomas, S Vithiananthan, J Unick, J Webster, G D Roye, B A Ryder, H C Sax
Higher preoperative physical activity (PA) strongly predicts higher post-operative PA in bariatric surgery (BS) patients, providing rationale for preoperative PA interventions (PAIs). However, whether PAI-related increases can be maintained post-operatively has not been examined. This study compared PA changes across pre- (baseline, post-intervention) and post-operative (6-month follow up) periods in participants randomized to 6 weeks of preoperative PAI or standard care control (SC). Of 75 participants initially randomized, 36 (PAI n=22; SC n=14) underwent BS...
March 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27890632/evidence-of-genotypes-1-and-3-of-avian-hepatitis-e-virus-in-wild-birds
#7
Xinquan Zhang, Ivana Bilic, Salome Troxler, Michael Hess
Although the presence of four genotypes of avian hepatitis E virus (HEV) in chickens has been demonstrated, its natural host range is still barely known. In this study, swab samples from 626 wild birds originating from 62 bird species were investigated for HEV detection by molecular methods. The aim was to explore the cross-species infection of avian HEV and to compare the genetic diversity between strains infecting chicken and wild birds. In total, 8 positive samples from 4 different bird species (song thrush, little owl, feral pigeon and common buzzard) were identified and further confirmed by partial sequencing of ORF3...
January 15, 2017: Virus Research
https://www.readbyqxmd.com/read/27878226/psychometric-properties-of-multidimensional-health-locus-of-control-a-and-general-self-efficacy-scale-in-civil-servants-elsa-brasil-musculoskeletal-study-elsa-brasil-msk
#8
Luciana A C Machado, Rosa W Telles, Luciana Costa-Silva, Sandhi M Barreto
Background: Health-related control and self-efficacy beliefs can be assessed in the general population using Multidimensional Health Locus of Control-A subscales (MHLC-A) and the General Self-Efficacy Scale (GSES), respectively. Objective: To test construct validity, internal consistency, reliability (test-retest) and ceiling and floor effects of Portuguese-Brazil versions of MHLC-A and GSES. Method: Civil servants (N=2901) enrolled in a large Brazilian cohort were included...
June 30, 2016: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/27709265/increased-incidence-of-co-infection-in-critically-ill-patients-with-influenza
#9
Ignacio Martin-Loeches, Marcus J Schultz, Jean-Louis Vincent, Francisco Alvarez-Lerma, Lieuwe D Bos, Jordi Solé-Violán, Antoni Torres, Alejandro Rodriguez
BACKGROUND: Co-infection is frequently seen in critically ill patients with influenza, although the exact rate is unknown. We determined the rate of co-infection, the risk factors and the outcomes associated with co-infection in critically ill patients with influenza over a 7-year period in 148 Spanish intensive care units (ICUs). METHODS: This was a prospective, observational, multicentre study. Influenza was diagnosed using the polymerase chain reaction. Co-infection had to be confirmed using standard bacteriological tests...
January 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/27677621/trajectories-of-total-and-central-adiposity-throughout-adolescence-and-cardiometabolic-factors-in-early-adulthood
#10
J Araújo, H Barros, E Ramos, L Li
BACKGROUND/OBJECTIVES: Our aim was to identify trajectories of total and central adiposity from 13 to 21 years, and to investigate how adiposity changes at different phases of adolescence relate to adulthood cardiovascular risk factors. SUBJECTS/METHODS: This study included participants from a population-based cohort (EPITeen), Portugal. Body mass index (BMI) and waist circumference (WC) were measured at 13, 17 and 21 years, and sex- and age-specific z-scores were calculated...
December 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27555176/use-of-cuffed-tracheal-tubes-in-neonates-infants-and-children-a-practice-survey-of-members-of-the-society-of-pediatric-anesthesia
#11
Madhankumar Sathyamoorthy, Jerrold Lerman, Victoria I Okhomina, Alan D Penman
STUDY OBJECTIVE: This study aimed to characterize the current practice patterns with cuffed tracheal tubes (CTT) in neonates, infants, and children among members of the Society of Pediatric Anesthesia (SPA). DESIGN AND SETTING: An electronic mail survey was distributed using Survey Monkey to members of SPA between December 2013 and February 2014. Each member was permitted one response. PATIENTS/INTERVENTION/MEASUREMENTS: Not applicable as this is a practice survey study...
September 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27361470/effect-of-raw-acceleration-filtering-methods-on-the-relationship-between-accelerometer-outputs-and-energy-expenditure-2901-june-3-2-45-pm-3-00-pm
#12
John M Schuna, Daniel S Hsia, William D Johnson, Catrine Tudor-Locke
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27216214/prevalence-and-risk-factors-of-chronic-obstructive-pulmonary-diseases-in-a-hlai-community-in-hainan-island-of-china
#13
Yipeng Ding, Danlei Yang, Ping He, Jinjian Yao, Pei Sun, Quanni Li, Pingdong Xie, Daobo Lin, Dingwei Sun, Huan Niu, Zhongjie Tian
OBJECTIVES: We investigated prevalence and risk factors of chronic obstructive pulmonary disease (COPD) in a population of Hlai (the Li) ethnicity, a major minority, in Qicha Town, Changjiang County, Hainan Province, PRC, during 2014. METHODS: All residents at the age of 40 years or older were interviewed with standardized questionnaires. Spirometry was performed to measure the possible airflow limitation. According to the GOLD criteria, post bronchodilator FEV1/FVC<70% was defined as COPD...
May 23, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27196952/prevalence-and-causes-of-visual-impairment-and-blindness-in-chinese-american-adults-the-chinese-american-eye-study
#14
Rohit Varma, Jeniffer S Kim, Bruce S Burkemper, Ge Wen, Mina Torres, Chunyi Hsu, Farzana Choudhury, Stanley P Azen, Roberta McKean-Cowdin
IMPORTANCE: Visual impairment (VI) and blindness continue to be major public health problems worldwide. Despite previously published studies on VI in Chinese and other racial/ethnic populations, there are no data specific to Chinese American adults. OBJECTIVES: To determine the age- and sex-specific prevalence and causes of VI and blindness in adult Chinese Americans and to compare the prevalence to other racial/ethnic groups. DESIGN, SETTING, AND PARTICIPANTS: In this population-based, cross-sectional study of 10 US Census tracts in the city of Monterey Park, California, 4582 Chinese American adults 50 years and older underwent complete ophthalmologic examinations, including measurement of presenting and best-corrected visual acuity (BCVA) for distance using the Early Treatment Diabetic Retinopathy Study protocol from February 1, 2010, through October 31, 2013...
July 1, 2016: JAMA Ophthalmology
https://www.readbyqxmd.com/read/27133095/changes-in-food-specific-ige-over-time-in-the-national-health-and-nutrition-examination-survey-nhanes
#15
Emily C McGowan, Roger D Peng, Päivi M Salo, Darryl C Zeldin, Corinne A Keet
BACKGROUND: Food allergy prevalence appears to have recently risen, with larger increases among non-Hispanic blacks. However, it is unclear whether these trends represent shifts in recognition of food allergy or in sensitization. OBJECTIVE: The objective of this study was to determine whether sensitization to common food allergens increased in US children from 1988-1994 to 2005-2006 and whether these trends differed by race and/or ethnicity. METHODS: Food-specific immunoglobulin E (IgE; to peanut, milk, egg, and shrimp) was measured by ImmunoCAP in stored sera from subjects aged 6-19 in the National Health and Nutrition Examination Survey (NHANES) III (1988-1994) and was compared with NHANES 2005-2006...
July 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27129000/long-term-retrospective-evaluation-of-dental-implants-placed-in-resorbed-jaws-reconstructed-with-appositional-fresh-frozen-bone-allografts
#16
Carlo Maiorana, Pier Paolo Poli, Andrea Enrico Borgonovo, Davide Rancitelli, Anna Chiara Frigo, Stefano Pieroni, Franco Santoro
INTRODUCTION: The aim of this study was to evaluate the outcome of fresh-frozen bone allografts in preprosthetic surgery for implant placement purposes. MATERIALS AND METHODS: The cohort comprised 45 patients treated with fresh-frozen bone block grafts and dental implants. Clinical and radiological evaluations were performed to evaluate the survival rate. The data were statistically analyzed with the Kaplan-Meier estimator to assess the influence of possible predictors of implant failure on survival...
June 2016: Implant Dentistry
https://www.readbyqxmd.com/read/26957935/the-total-work-measured-during-a-high-intensity-isokinetic-fatigue-test-is-associated-with-anaerobic-work-capacity
#17
Laurent Bosquet, Kenan Gouadec, Nicolas Berryman, Cyril Duclos, Vincent Gremeaux, Jean Louis Croisier
The purpose of the study was to determine whether total work measured during a high intensity isokinetic fatigue test (TWFAT) could be considered as a valid measure of anaerobic work capacity (AWC), such as determined by total work measured during a Wingate Anaerobic Test (TWWAnT). Twenty well-trained cyclists performed 2 randomly ordered sessions involving a high intensity isokinetic fatigue test consisting in 30 reciprocal maximal concentric contractions of knee flexors and extensors at 180°·s(-1), and a Wingate Anaerobic Test...
March 2016: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/26893071/physical-activity-and-non-movement-behaviours-their-independent-and-combined-associations-with-metabolic-syndrome
#18
Deepa P Rao, Heather Orpana, Daniel Krewski
BACKGROUND: Metabolic syndrome (MetS) is a prevalent risk condition associated with a higher risk of chronic conditions, including diabetes and cardiovascular diseases. Physical activity and non-movement behaviours (NMB), including sleep, screen time and sedentary activity, have been associated with MetS. In light of the increasing prevalence of NMBs, and the moderate rates of physical activity guideline adherence in Canada, this analysis examines the independent and combined associations of NMB and physical activity with MetS...
2016: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/26892991/impact-of-human-papillomavirus-hpv-16-and-18-vaccination-on-prevalent-infections-and-rates-of-cervical-lesions-after-excisional-treatment
#19
Allan Hildesheim, Paula Gonzalez, Aimee R Kreimer, Sholom Wacholder, John Schussler, Ana C Rodriguez, Carolina Porras, Mark Schiffman, Mary Sidawy, John T Schiller, Douglas R Lowy, Rolando Herrero
BACKGROUND: Human papillomavirus vaccines prevent human papillomavirus infection and cervical precancers. The impact of vaccinating women with a current infection or after treatment for an human papillomavirus-associated lesion is not fully understood. OBJECTIVES: To determine whether human papillomavirus-16/18 vaccination influences the outcome of infections present at vaccination and the rate of infection and disease after treatment of lesions. STUDY DESIGN: We included 1711 women (18-25 years) with carcinogenic human papillomavirus infection and 311 women of similar age who underwent treatment for cervical precancer and who participated in a community-based trial of the AS04-adjuvanted human papillomavirus-16/18 virus-like particle vaccine...
August 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26870428/crystal-structure-of-bis-acetonyltri-phenyl-phospho-nium-tetra-chlorido-cobaltate-ii
#20
Mouhamadou Birame Diop, Libasse Diop, Allen G Oliver
The complex title salt, (C21H20OP)2[CoCl4], is the reaction product of CoCl2 with acetonyltri-phenyl-phospho-nium chloride in aceto-nitrile. In the anion, the Co(II) atom exhibits a typical tetra-hedral environment, with Co-Cl distances ranging from 2.2721 (6) to 2.2901 (6) Å, and with Cl-Co-Cl angles ranging from 106.12 (2) to 112.24 (2)°. The two phospho-nium cations likewise show the expected tetra-hedral configuration, with P-C distances ranging from 1.785 (2) to 1.8059 (18) Å and C-P-C angles ranging from 106...
December 1, 2015: Acta Crystallographica. Section E, Crystallographic Communications
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