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https://www.readbyqxmd.com/read/28629811/tbt-and-its-metabolites-in-sediments-survey-at-a-german-coastal-site-and-the-central-baltic-sea
#1
Marion Abraham, Lina Westphal, Ines Hand, Astrid Lerz, Jenny Jeschek, Dennis Bunke, Thomas Leipe, Detlef Schulz-Bull
Since the 1950s the organotin compound tributyltin (TBT) was intensively used in antifouling paints for marine vessels and it became of concern for the marine environment. Herein, we report on a study from 2015 on TBT and its metabolites monobutyltin (MBT) and dibutyltin (DBT) in sediments from the central Baltic Sea and a Baltic Sea coastal site with strong harbor activities (Warnemünde). Sublayers from a sediment core from the Arkona Basin were analyzed to investigate the long term organotin pressure for the Baltic Sea...
June 16, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28617103/effects-of-mindfulness-based-therapies-for-female-sexual-dysfunction-a-meta-analytic-review
#2
Kyle R Stephenson, Jonathan Kerth
Mindfulness-based therapy (MBT) represents a potentially efficacious treatment for female sexual dysfunction (FSD). A number of recent trials assessing MBT for FSD have been published, but we are aware of no existing meta-analysis synthesizing these results. We conducted a literature review to identify all published trials of MBT for FSD. References of retrieved studies were searched and key authors were contacted with requests for complete but unpublished trials. Eleven trials, including a total of 449 participants, were identified...
June 15, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28614044/validation-of-odour-concentration-from-mbt-piles-using-static-chamber-and-wind-tunnel-with-the-different-wind-speed-values
#3
Mirosław Szyłak-Szydłowski
The basic principle of odour sampling from surface sources is based primarily on the amount of air obtained from a specific area of the ground, which acts as a source of malodourous compounds. Wind tunnels and flux chambers are often the only available, direct method of evaluating the odour fluxes from small area sources. There are currently no widely accepted chamber-based methods, thus there is still a need for standardization of them to ensure accuracy and comparability. Previous research has established that there is a significant difference between the odour concentration values obtained using the Lindvall chamber and those obtained by a dynamic flow chamber...
June 14, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/28595542/synthesis-of-99mtc-rifabutin-a-potential-tuberculosis-radiodiagnostic-agent
#4
Syed Qaiser Shah, Mamoona Alam
BACKGROUND: Rifabutin (RFN) is bactericidal antibiotic with a very broad spectrum of activity against gram positive & gram negative organisms including Pseudomonas aeruginosa and specifically Mycobacterium tuberculosis. OBJECTIVE: RFN inhibits DNA dependent RNA polymerase activity in susceptible cells. In the instant work, the therapeutic characteristics of RFN were intended for diagnostic rationale by labeling it with 99mTc (Technetium-99m). The 99mTc labeled RFN (99mTc-RFN) was investigated for labeling capacity, steadiness in saline & serum, in vitro Mycobacterium tuberculosis (MBT) uptake & distribution in MBT stained animal model rats...
June 5, 2017: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/28566855/assessment-of-bracket-surface-morphology-and-dimensional-change
#5
Pillai Devu Radhakrishnan, N K Sapna Varma, V V Ajith
OBJECTIVE: The objective of this study was to compare the surface morphology and dimensional stability of the bracket slot at the onset of treatment and after 12 months of intraoral exposure. The study also compared the amount of calcium at the bracket base which indicates enamel loss among the three orthodontic brackets following debonding after 12 months of intraoral exposure. MATERIALS AND METHODS: The sample consisted of 60 (0.022" MBT) canine brackets. They were divided into three groups: self-ligating, ceramic bracket with metal slot, and stainless steel (SS) brackets...
January 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/28559583/many-body-tunneling-and-nonequilibrium-dynamics-of-doublons-in-strongly-correlated-quantum-dots
#6
WenJie Hou, YuanDong Wang, JianHua Wei, ZhenGang Zhu, YiJing Yan
Quantum tunneling dominates coherent transport at low temperatures in many systems of great interest. In this work we report a many-body tunneling (MBT), by nonperturbatively solving the Anderson multi-impurity model, and identify it a fundamental tunneling process on top of the well-acknowledged sequential tunneling and cotunneling. We show that the MBT involves the dynamics of doublons in strongly correlated systems. Proportional to the numbers of dynamical doublons, the MBT can dominate the off-resonant transport in the strongly correlated regime...
May 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28552546/use-of-the-crispr-cas9-system-for-genome-editing-in-cultured-drosophila-ovarian-somatic-cells
#7
Hirotsugu Ishizu, Tetsutaro Sumiyoshi, Mikiko C Siomi
The CRISPR-Cas9 system can be used for genome engineering in many organisms. PIWI-interacting RNAs (piRNAs) play a crucial role in repressing transposons to maintain genome integrity in Drosophila ovaries, and cultured ovarian somatic cells (OSCs) are widely used to elucidate the molecular mechanisms underlying the piRNA pathway. However, the germline-specific piRNA amplification system known as the ping-pong machinery does not occur in OSCs, making them unsuitable for elucidating the underlying mechanisms...
May 25, 2017: Methods: a Companion to Methods in Enzymology
https://www.readbyqxmd.com/read/28521384/analysis-of-tenodesis-techiques-for-treatment-of-scapholunate-instability-using-the-finite-element-method
#8
Teresa Alonso Rasgado, Qinghang Zhang, David Jimenez Cruz, Colin Bailey, Elizabeth Pinder, Avanthi Mandaleson, Sumedh Talwalkar
Chronic Scapholunate ligament (SL) injuries are difficult to treat and can lead to wrist dysfunction. Whilst several tendon reconstruction techniques have been employed in the management of SL instability, SL gap reappearance after surgery has been reported. Using finite element model and cadaveric study data we investigated the performance of the Corella, schapolunate axis (SLAM) and modified Brunelli tenodesis (MBT) techniques. Virtual tenodesis surgery was undertaken in 3D finite element (FE) models to obtain the scapholunate (SL) gap and angle resulting from the three reconstruction techniques...
May 18, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/28515048/essential-function-of-the-serine-hydroxymethyl-transferase-shmt-gene-during-rapid-syncytial-cell-cycles-in-drosophila
#9
Franziska Winkler, Maria Kriebel, Michaela Clever, Stephanie Gröning, Jörg Großhans
Many metabolic enzymes are evolutionary highly conserved and serve a central function for catabolism and anabolism of cells. The serine hydroxymethyl transferase (SHMT) catalysing the conversion of serine and glycine and vice versa feeds into the tetrahydrofolate mediated C1 metabolism. We identified a Drosophila mutation in SHMT (CG3011) in a screen for blastoderm mutants. Embryos from SHMT mutant germline clones specifically arrest the cell cycle in interphase 13 at the time of the mid blastula transition (MBT) and prior to cellularisation...
May 17, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28513880/unstable-rocker-shoes-promote-recovery-from-marathon-induced-muscle-damage-in-novice-runners
#10
Kento Nakagawa, Takayuki Inami, Takahisa Yonezu, Yuta Kenmotsu, Takaya Narita, Yasuo Kawakami, Kazuyuki Kanosue
We recently reported that wearing unstable rocker shoes (Masai Barefoot Technology: MBT) may enhance recovery from marathon race induced fatigue. However, this earlier study only utilized a questionnaire. In the present study, we evaluated MBT utilizing objective physiological measures of recovery from marathon induced muscle damages. Twenty-five university student novice runners were divided into two groups. After running a full marathon, one group wore MBT shoes (MBT group), and the control group (CON) wore ordinary shoes daily for one week following the race...
May 17, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28506668/characterization-of-selected-municipal-solid-waste-components-to-estimate-their-biodegradability
#11
R Bayard, H Benbelkacem, R Gourdon, P Buffière
Biological treatments of Residual Municipal Solid Waste (RMSW) allow to divert biodegradable materials from landfilling and recover valuable alternative resources. The biodegradability of the waste components needs however to be assessed in order to design the bioprocesses properly. The present study investigated complementary approaches to aerobic and anaerobic biotests for a more rapid evaluation. A representative sample of residual MSW was collected from a Mechanical Biological Treatment (MBT) plant and sorted out into 13 fractions according to the French standard procedure MODECOM™...
May 12, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28505220/multicenter-evaluation-of-the-bruker-maldi-biotyper-ca-system-for-the-identification-of-clinically-important-bacteria-and-yeasts
#12
Deborah A Wilson, Stephen Young, Karen Timm, Susan Novak-Weekley, Elizabeth M Marlowe, Neil Madisen, Jennifer L Lillie, Nathan A Ledeboer, Rebecca Smith, Josh Hyke, Christen Griego-Fullbright, Patricia Jim, Paul A Granato, Matthew L Faron, Joven Cumpio, Blake W Buchan, Gary W Procop
Objectives: A report on the multicenter evaluation of the Bruker MALDI Biotyper CA System (MBT-CA; Bruker Daltonics, Billerica, MA) for the identification of clinically important bacteria and yeasts. Methods: In total, 4,399 isolates of medically important bacteria and yeasts were assessed in the MBT-CA. These included 2,262 aerobic gram-positive (AGP) bacteria, 792 aerobic gram-negative (AGN) bacteria 530 anaerobic (AnA) bacteria, and 815 yeasts (YSTs). Three processing methods were assesed...
June 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28504676/developing-spindlin1-small-molecule-inhibitors-by-using-protein-microarrays
#13
Narkhyun Bae, Monica Viviano, Xiaonan Su, Jie Lv, Donghang Cheng, Cari Sagum, Sabrina Castellano, Xue Bai, Claire Johnson, Mahmoud Ibrahim Khalil, Jianjun Shen, Kaifu Chen, Haitao Li, Gianluca Sbardella, Mark T Bedford
The discovery of inhibitors of methyl- and acetyl-binding domains has provided evidence for the 'druggability' of epigenetic effector molecules. The small-molecule probe UNC1215 prevents methyl-dependent protein-protein interactions by engaging the aromatic cage of MBT domains and, with lower affinity, Tudor domains. Using a library of tagged UNC1215 analogs, we screened a protein-domain microarray of human methyllysine effector molecules to rapidly detect compounds with new binding profiles with either increased or decreased specificity...
July 2017: Nature Chemical Biology
https://www.readbyqxmd.com/read/28498870/brg1-chromatin-remodeling-atpase-balances-germ-layer-patterning-by-amplifying-the-transcriptional-burst-at-midblastula-transition
#14
Gabriele Wagner, Nishant Singhal, Dario Nicetto, Tobias Straub, Elisabeth Kremmer, Ralph A W Rupp
Zygotic gene expression programs control cell differentiation in vertebrate development. In Xenopus, these programs are initiated by local induction of regulatory genes through maternal signaling activities in the wake of zygotic genome activation (ZGA) at the midblastula transition (MBT). These programs lay down the vertebrate body plan through gastrulation and neurulation, and are accompanied by massive changes in chromatin structure, which increasingly constrain cellular plasticity. Here we report on developmental functions for Brahma related gene 1 (Brg1), a key component of embyronic SWI/SNF chromatin remodeling complexes...
May 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28488379/barriers-and-facilitators-to-the-implementation-of-mentalization-based-treatment-mbt-for-borderline-personality-disorder
#15
Dawn L Bales, Roel Verheul, Joost Hutsebaut
There are several evidence-based treatments for borderline personality disorder, but very little is known about the success or failure of implementation in daily practice. This study aims to investigate the success or failure of newly started mentalization-based treatment programs, and to explore the barriers and facilitators. The implementation trajectories of seven different mentalization-based treatment programs in six mental health clinics in the Netherlands were included in a multiple case study combining a qualitative and quantitative design...
May 2017: Personality and Mental Health
https://www.readbyqxmd.com/read/28487778/cl-ii-malocclusion-treatment-using-the-modified-twin-block-appliance-coordinated-with-fixed-orthodontics-in-a-postmenarche-patient
#16
Amin Aminian, Shahriar Sarvareh Azimzadeh, Elina Rahmanian
Functional appliances have been used for treatment of Class II patients for a long time. The main objective of therapy with functional appliances is to induce supplementary lengthening of the mandible by stimulating increased growth at the condylar cartilage. The Twin Block appliance is one of the most commonly used functional appliances. The aim of this paper is to present a case report of mandibular deficiency treatment with Twin Block appliance in a female patient whose sexual maturation (one and a half years after menarche) and cervical vertebral maturation stage indicated the end of the growth peak...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28486429/mechanics-based-tomography-a-preliminary-feasibility-study
#17
Yue Mei, Sicheng Wang, Xin Shen, Stephen Rabke, Sevan Goenezen
We present a non-destructive approach to sense inclusion objects embedded in a solid medium remotely from force sensors applied to the medium and boundary displacements that could be measured via a digital image correlation system using a set of cameras. We provide a rationale and strategy to uniquely identify the heterogeneous sample composition based on stiffness (here, shear modulus) maps. The feasibility of this inversion scheme is tested with simulated experiments that could have clinical relevance in diagnostic imaging (e...
May 9, 2017: Sensors
https://www.readbyqxmd.com/read/28470325/continuous-fabrication-of-microcapsules-with-controllable-metal-covered-nanoparticle-arrays-using-droplet-microfluidics-for-localized-surface-plasmon-resonance
#18
Juan Wang, Mingliang Jin, Yingxin Gong, Hao Li, Sujuan Wu, Zhang Zhang, Guofu Zhou, Lingling Shui, Jan C T Eijkel, Albert van den Berg
The construction of ordered nanoparticle arrays is important for nanophotonics and sensing applications. We report a facile technology for continuous-flow fabrication of particle-laden plasmonic microcapsules (PLPMs) by combining droplet microfluidics, nanoparticle self-assembly and thin film deposition. The metallic hierarchical nanostructures on PLPMs are presented with high-density "hot-spot" scattering sites with the nanoarray pitch and gap distance being controlled by the deposited metal film thickness and nanoparticle size...
May 31, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28468565/-mentalization-based-treatment-of-an-adolescent-girl-with-conduct-disorder
#19
Melanie Reiter, Astrid Bock, Marie-Luise Althoff, Svenja Taubner, Kathrin Sevecke
Mentalization Based Treatment of an Adolescent Girl with Conduct Disorder This paper will give a short overview on the theoretical concept of mentalization and its specific characteristics in adolescence. A previous study on Mentalization based treatment for adolescents (MBT-A) demonstrated the effectiveness of MBT-A for the treatment of adolescents with symptoms of deliberate self-harm (Rossouw u. Fonagy, 2012). Based on the results of this study Taubner, Gablonski, Sevecke, and Volkert (in preparation) developed a manual for mentalization based treatment for adolescents with conduct disorders (MBT-CD)...
May 2017: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://www.readbyqxmd.com/read/28464298/yield-cultivation-of-magnetotactic-bacteria-and-magnetosomes-a-review
#20
REVIEW
Imran Ali, Changsheng Peng, Zahid M Khan, Iffat Naz
Magnetotactic bacteria (MTB) have started to be employed for the biosynthesis of magnetic nanoparticles, due to the rapidly increasing demand for nanoparticles in biomedical, biotechnology and environmental protection. MBT are the group of prokaryotes that have the ability to produce bio-magnetic minerals or bio-magnetic crystals of either magnetite (Fe3 O4 ) or greigite (Fe3 S4 ) in numerous shapes and size ranges, known as magnetosomes (MS). MS compel MTB to respond to the applied external magnetic field...
May 2, 2017: Journal of Basic Microbiology
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