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https://www.readbyqxmd.com/read/28917811/electrochemical-characterization-of-in-situ-functionalized-gold-organosulfur-self-assembled-monolayer-with-conducting-polymer-and-carbon-nanotubes-for-determination-of-rutin
#1
Majid Arvand, Mona Farahpour, Masoomeh Sayyar Ardaki
In this study, attempts were made to present a sensitive strategy for determining rutin. To reach the goal of the study, a poly(sulfosalicylic acid) film was electropolymerized on a gold electrode, which was modified by 2-mercaptobenzothiazole self-assembled monolayer and multi-walled carbon nanotubes (PSSA/CNTs/MBT/Au). The proposed sensor was characterized by different techniques including field emission scanning electron microscopy, energy dispersive X-ray spectroscopy and Fourier transform infrared spectroscopy...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28913787/mortality-rates-and-risk-factors-for-emergent-open-repair-of-abdominal-aortic-aneurysms-in-the-endovascular-era
#2
Felice Pecoraro, Steffen Gloekler, Caecilia E Mader, Malgorzata Roos, Lyubov Chaykovska, Frank J Veith, Neal S Cayne, Nicola Mangialardi, Thomas Neff, Mario Lachat
The background of this paper is to report the mortality at 30 and 90 days and at mean follow-up after open abdominal aortic aneurysms (AAA) emergent repair and to identify predictive risk factors for 30- and 90-day mortality. Between 1997 and 2002, 104 patients underwent emergent AAA open surgery. Symptomatic and ruptured AAAs were observed, respectively, in 21 and 79% of cases. Mean patient age was 70 (SD 9.2) years. Mean aneurysm maximal diameter was 7.4 (SD 1.6) cm. Primary endpoints were 30- and 90-day mortality...
September 14, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28881578/the-establishment-of-a-growth-controllable-orthotopic-bladder-cancer-model-through-the-down-regulation-of-c-myc-expression
#3
Ho Kyung Seo, Seung-Phil Shin, Na-Rae Jung, Whi-An Kwon, Kyung-Chae Jeong, Sang-Jin Lee
To properly evaluate the biological effects of immunotherapy, it is critical to utilize a model of cancer in immune-competent mice. Currently, MBT-2 is the most common murine bladder cancer cell line used in orthotopic bladder cancer models, even though this cell type often has an inappropriate genetic mutation landscape. In these models, after tumors are detected with in vivo imaging, the mouse usually dies within two to three weeks due to post-renal azotemia caused by the rapidly growing mass. This event prohibits the evaluation of tumor behavior upon intravesical drug treatment...
August 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28877351/evaluation-of-a-novel-collimator-for-molecular-breast-tomosynthesis
#4
David R Gilland, Benjamin L Welch, Seungjoon Lee, Brian Kross, Andrew G Weisenberger
PURPOSE: This study investigated a novel gamma camera for molecular breast tomosynthesis (MBT), which is a nuclear breast imaging method that uses limited angle tomography. The camera is equipped with a variable angle, slant-hole (VASH) collimator that allows the camera to remain close to the breast throughout the acquisition. The goal of this study was to evaluate the spatial resolution and count sensitivity of this camera and to compare contrast and contrast-to-noise ratio (CNR) with conventional planar imaging using an experimental breast phantom...
September 6, 2017: Medical Physics
https://www.readbyqxmd.com/read/28866454/gait-abnormalities-of-copd-are-not-directly-related-to-respiratory-function
#5
Paola Morlino, Bruno Balbi, Simone Guglielmetti, Marica Giardini, Margherita Grasso, Chiara Giordano, Marco Schieppati, Antonio Nardone
STUDY OBJECTIVE: To assess whether gait abnormalities in COPD depend on mere impairment of respiratory function. METHODS: In 40 patients with COPD at different GOLD stages and 28 controls, we evaluated: forced expiratory volume in 1s (FEV1); partial pressure of oxygen; Mini-Mental State Examination (MMSE); dynamic balance through the Mini-BESTest (MBT); Timed Up and Go (TUG) test without and with dual task counting aloud back by three; 6-min walk test (6MWT); body sway during quiet stance (stabilometry); spatial-temporal variables of gait by a 4-m long sensorized walkway (baropodometry)...
August 18, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28866279/simulation-of-the-behavior-of-a-refuse-landfill-on-a-laboratory-scale
#6
Joan Esteban-Altabella, Francisco J Colomer-Mendoza, Antonio Gallardo-Izquierdo
The characteristics and properties of waste in a landfill, and its evolution over time, are difficult to estimate because of the heterogeneity of materials, biomass degradation, density, cover material, and infiltration of water. In this work, a lysimeter was used to simulate how refuse from mechanical-biological treatment (MBT) plants evolved in a landfill over a 45-day period. Water was added as a way to imitate the effects produced during rainy seasons. Field capacity and changes in the physical and chemical properties (volatile solids, biomass, and heating value) were analyzed...
August 31, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28855394/an-in-vivo-genetic-screen-in-drosophila-identifies-the-orthologue-of-human-cancer-testis-gene-spo11-among-a-network-of-targets-to-inhibit-lethal-3-malignant-brain-tumour-growth
#7
Fabrizio Rossi, Cristina Molnar, Kazuya Hashiyama, Jan P Heinen, Judit Pampalona, Salud Llamazares, José Reina, Tomomi Hashiyama, Madhulika Rai, Giulia Pollarolo, Ismael Fernández-Hernández, Cayetano Gonzalez
Using transgenic RNAi technology, we have screened over 4000 genes to identify targets to inhibit malignant growth caused by the loss of function of lethal(3)malignant brain tumour in Drosophila in vivo We have identified 131 targets, which belong to a wide range of gene ontologies. Most of these target genes are not significantly overexpressed in mbt tumours hence showing that, rather counterintuitively, tumour-linked overexpression is not a good predictor of functional requirement. Moreover, we have found that most of the genes upregulated in mbt tumours remain overexpressed in tumour-suppressed double-mutant conditions, hence revealing that most of the tumour transcriptome signature is not necessarily correlated with malignant growth...
August 2017: Open Biology
https://www.readbyqxmd.com/read/28845176/effects-of-mind-body-training-on-cytokines-and-their-interactions-with-catecholamines
#8
Joon Hwan Jang, Hye Yoon Park, Ui Soon Lee, Kyung-Jun Lee, Do-Hyung Kang
OBJECTIVE: Mind-body training (MBT) may control reactions to stress and regulate the nervous and immune systems. The present study was designed to assess the effects of MBT on plasma cytokines and their interactions with catecholamines. METHODS: The study group consisted of 80 subjects who practice MBT and a control group of 62 healthy subjects. Plasma catecholamine (norepinephrine, NE; epinephrine, E; and dopamine, DA) and cytokine (TNF-alpha, IL-6, IFN-gamma, and IL-10) levels were measured, and the differences between the MBT and control groups and the interactions of cytokines with catecholamines were investigated...
July 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/28838769/evaluation-of-the-rotary-drum-reactor-process-as-pretreatment-technology-of-municipal-solid-waste-for-thermophilic-anaerobic-digestion-and-biogas-production
#9
Petros Gikas, Baoning Zhu, Nicolas Ion Batistatos, Ruihong Zhang
Municipal solid waste (MSW) contains a large fraction of biodegradable organic materials. When disposed in landfills, these materials can cause adverse environmental impact due to gaseous emissions and leachate generation. This study was performed with an aim of effectively separating the biodegradable materials from a Mechanical Biological Treatment (MBT) facility and treating them in well-controlled anaerobic digesters for biogas production. The rotary drum reactor (RDR) process (a sub-process of the MBT facilities studied in the present work) was evaluated as an MSW pretreatment technology for separating and preparing the biodegradable materials in MSW to be used as feedstock for anaerobic digestion...
August 21, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28801588/both-nuclear-size-and-dna-amount-contribute-to-midblastula-transition-timing-in-xenopus-laevis
#10
Predrag Jevtić, Daniel L Levy
During early Xenopus laevis embryogenesis both nuclear and cell volumes decrease with the nuclear-to-cytoplasmic (N/C) volume ratio reaching a maximum at the midblastula transition (MBT). At the MBT, embryonic transcription is upregulated and cell cycles lengthen. Early studies demonstrated a role for the DNA-to-cytoplasmic ratio in the control of MBT timing. By altering nuclear size, we previously showed that the N/C volume ratio also contributes to proper MBT timing. Here we examine the relative contributions of nuclear size and DNA amount to MBT timing by simultaneously altering nuclear size and ploidy in X...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28789618/genome-wide-copy-number-variation-analysis-identified-deletions-in-sfmbt1-associated-with-fasting-plasma-glucose-in-a-han-chinese-population
#11
Ren-Hua Chung, Yen-Feng Chiu, Yi-Jen Hung, Wen-Jane Lee, Kwan-Dun Wu, Hui-Ling Chen, Ming-Wei Lin, Yii-Der I Chen, Thomas Quertermous, Chao A Hsiung
BACKGROUND: Fasting glucose and fasting insulin are glycemic traits closely related to diabetes, and understanding the role of genetic factors in these traits can help reveal the etiology of type 2 diabetes. Although single nucleotide polymorphisms (SNPs) in several candidate genes have been found to be associated with fasting glucose and fasting insulin, copy number variations (CNVs), which have been reported to be associated with several complex traits, have not been reported for association with these two traits...
August 8, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28783602/organotin-compounds-in-brachidontes-rodriguezii-mussels-from-the-bah%C3%A3-a-blanca-estuary-argentina
#12
Pamela Y Quintas, Andrés H Arias, Ana L Oliva, Claudia E Domini, Mónica B Alvarez, Mariano Garrido, Jorge E Marcovecchio
Levels of tributyltin and its breakdown compounds, including the first record of monobutyltin (MBT) in history for Latin America, were determined in native mussels (Brachidontes rodriguezii) by means of CG-MS, after extraction/derivatization assisted by ultrasound. The samples were collected in 2013 in Bahía Blanca Estuary (Argentina) at 6 sites, which reflect different levels of maritime activities. Total butyltins (TBts = TBT+ DBT+ MBT) levels ranged from 19.64 to 180.57ng Sn g(-1) dry weight. According to the Oslo-Paris commission, the results indicated that 73...
August 4, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28769107/innate-immune-basis-for-rift-valley-fever-susceptibility-in-mouse-models
#13
Rashida Lathan, Dominique Simon-Chazottes, Grégory Jouvion, Ophélie Godon, Marie Malissen, Marie Flamand, Pierre Bruhns, Jean-Jacques Panthier
Rift Valley fever virus (RVFV) leads to varied clinical manifestations in animals and in humans that range from moderate fever to fatal illness, suggesting that host immune responses are important determinants of the disease severity. We investigated the immune basis for the extreme susceptibility of MBT/Pas mice that die with mild to acute hepatitis by day 3 post-infection compared to more resistant BALB/cByJ mice that survive up to a week longer. Lower levels of neutrophils observed in the bone marrow and blood of infected MBT/Pas mice are unlikely to be causative of increased RVFV susceptibility as constitutive neutropenia in specific mutant mice did not change survival outcome...
August 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28758571/experimental-simulation-and-fuzzy-modelling-of-landfill-biogas-production-from-low-biodegradable-mbt-waste-under-leachate-recirculation
#14
Martina Di Addario, Bernardo Ruggeri
In the perspective of a sustainable waste management, the amount of biodegradable municipal solid waste destined to landfilling should be reduced. In such context, new technologies have been developed in recent years with the aim of a more rapid stabilization of the waste. In this work, the combination of waste pretreatments and leachate recirculation was studied. A lab-scale experimental approach and a fuzzy-modelling approach were chosen to predict cumulative methane production from low biodegradable waste under leachate recirculation...
July 31, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28745946/mentalization-based-treatment-for-borderline-personality-disorder-in-adults-and-adolescents-for-whom-when-and-how
#15
Dine J Feenstra, Patrick Luyten, Dawn L Bales
Borderline personality disorder (BPD) is common in clinical practice. Psychotherapy is the treatment of choice, and mentalization-based treatment (MBT) is one of the empirically supported treatments that are currently available. For adults, two variants of MBT (MBT day hospital [MBT-DH] and MBT intensive outpatient [MBT-IOP]) have been developed and empirically evaluated. The authors review research on the development, efficacy, and implementation of MBT. In conclusion, the authors focus on the implementation of treatment programs for BPD patients...
2017: Bulletin of the Menninger Clinic
https://www.readbyqxmd.com/read/28741997/paracoccus-hibiscisoli-sp-nov-isolated-from-the-rhizosphere-of-mugunghwa-hibiscus-syriacus
#16
Pei Lin, Zheng-Fei Yan, Kyung-Hwa Won, Jung-Eun Yang, Chang-Tian Li, MooChang Kook, Qi-Jun Wang, Tae-Hoo Yi
A Gram-reaction-negative, aerobic, non-motile, short-rod-shaped bacterium (THG-T2.31T) was isolated from the rhizosphere of Mugunghwa (Hibiscus syriacus). Growth occurred at 10-35 °C (optimum 28 °C), at pH 5.0-8.0 (optimum pH 7.0) and with 0-4.0 % NaCl (optimum 1.0 %). Based on 16S rRNA gene sequence analysis, the nearest phylogenetic neighbours of strain THG-T2.31T were identified as Paracoccus marcusii DSM 11574T (98.4 %), Paracoccus haeundaensis BC74171T (98.3 %), Paracoccus carotinifaciens E-396T (98...
July 26, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28726169/comparison-of-the-systemic-and-local-pharmacokinetics-of-clonidine-mucoadhesive-buccal-tablets-with-reference-clonidine-oral-tablets-in-healthy-volunteers-an-open-label-randomised-cross-over-trial
#17
Bérangère Vasseur, Alain Dufour, Laetitia Houdas, Helen Goodwin, Kathryn Harries, Neslihan Yesiltas Emul, Simon Hutchings
INTRODUCTION: The clonidine mucoadhesive buccal tablet (MBT) is a novel delivery system resulting in high and sustained concentrations of clonidine in the oral cavity. In a phase II clinical trial, clonidine MBT reduced the incidence of severe oral mucositis (OM) compared to placebo in head and neck cancer patients undergoing chemoradiation. This study compared the pharmacokinetics (PK), safety and tolerability of clonidine MBT with a reference oral tablet (OT). METHODS: This was a randomised, three-period, single-dose crossover study in 36 healthy subjects aged 18-50 years...
July 19, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28720113/evaluation-of-electric-nets-as-means-to-sample-mosquito-vectors-host-seeking-on-humans-and-primates
#18
Frances Hawkes, Benny Obrain Manin, Sui Han Ng, Stephen J Torr, Chris Drakeley, Tock H Chua, Heather M Ferguson
BACKGROUND: Plasmodium knowlesi is found in macaques and is the only major zoonotic malaria to affect humans. Transmission of P. knowlesi between people and macaques depends on the host species preferences and feeding behavior of mosquito vectors. However, these behaviours are difficult to measure due to the lack of standardized methods for sampling potential vectors attracted to different host species. This study evaluated electrocuting net traps as a safe, standardised method for sampling P...
July 18, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28718968/the-design-of-the-mbt-g-adherence-and-quality-scale
#19
Espen J Folmo, Sigmund W Karterud, Kjetil Bremer, Kristoffer L Walther, Elfrida H Kvarstein, Geir A F Pedersen
Few group psychotherapy studies focus on therapists' interventions, and instruments that can measure group psychotherapy treatment fidelity are scarce. The aim of the present study was to evaluate the reliability of the Mentalization-based Group Therapy Adherence and Quality Scale (MBT-G-AQS), which is a 19-item scale developed to measure adherence and quality in mentalization-based group therapy (MBT-G). Eight MBT groups and eight psychodynamic groups (a total of 16 videotaped therapy sessions) were rated independently by five raters...
August 2017: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/28701091/-mentalization-based-treatment-for-adolescents-with-borderline-personality-disorder-concept-and-efficacy
#20
Svenja Taubner, Jana Volkert, Thorsten-Christian Gablonski, Trudie Rossouw
Mentalization-Based Treatment for Adolescents with Borderline Personality Disorder - Concept and Efficacy In recent years, the concept of mentalization has become increasingly important in practice and research. It describes the imaginative ability to understand human behavior in terms of mental states. Mentalization is a central component to understand the etiology and to treat patients with borderline personality disorder (BPD). Both adult and adolescent patients with BPD have limited mentalization abilities, which can be reliably assessed using the Reflective Functioning Scale...
July 2017: Praxis der Kinderpsychologie und Kinderpsychiatrie
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