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https://www.readbyqxmd.com/read/28822256/addressing-harmful-algal-blooms-habs-impacts-with-ferrate-vi-simultaneous-removal-of-algal-cells-and-toxins-for-drinking-water-treatment
#1
Yang Deng, Meiyin Wu, Huiqin Zhang, Lei Zheng, Yaritza Acosta, Tsung-Ta D Hsu
Although ferrate(VI) has long been recognized as a multi-purpose treatment agent, previous investigations regarding ferrate(VI) for addressing harmful algal blooms (HABs) impacts in drinking water treatment only focused on a single HAB pollutant (e.g. algal cells or algal toxins). Moreover, the performance of ferrate(VI)-driven coagulation was poorly investigated in comparison with ferrate(VI) oxidation, though it has been widely acknowledged as a major ferrate(VI) treatment mechanism. We herein reported ferrate(VI) as an emerging agent for simultaneous and effective removal of algal cells and toxins in a simulated HAB-impacted water...
August 11, 2017: Chemosphere
https://www.readbyqxmd.com/read/28821421/exploring-canadian-physicians-experiences-with-diabetes-care-for-indigenous-patients
#2
Lynden Lindsay Crowshoe, Rita I Henderson, Michael E Green, Kristen M Jacklin, Leah M Walker, Betty Calam
OBJECTIVES: The perspectives of physicians caring for Indigenous patients with diabetes offer important insights into the provision of health-care services. The purpose of this study was to describe Canadian physicians' perspectives on diabetes care of Indigenous patients, a preliminary step in developing a continuing medical education intervention described elsewhere. METHODS: Through in-depth semistructured interviews, Canadian family physicians and specialists with sizeable proportions of Indigenous clientele shared their experiences of working with Indigenous patients who have type 2 diabetes...
August 15, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28819829/surgical-treatment-for-symptomatic-non-ossifying-fibromas-of-the-lower-extremity-with-calcium-sulfate-grafts-in-skeletally-immature-patients
#3
Antonio Andreacchio, Flavia Alberghina, Gianluca Testa, Federico Canavese
BACKGROUND: Non-ossifying fibromas (NOFs) are common benign bone lesions found in children and adolescents. They usually involve metaphysis of long bones, tend to gradually disappear with age and usually do not require surgery, while they are not associated with pathological fractures. The aim of this study was to evaluate the outcome and efficacy of a single-stage procedure, comprising curettage of the lesion and calcium sulfate pellet (CaSP) grafting, in skeletally immature patients with large, symptomatic NOF of the lower extremity, and the possible limitations of the procedure...
August 17, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28819690/conductance-based-refractory-density-approach-comparison-with-experimental-data-and-generalization-to-lognormal-distribution-of-input-current
#4
Anton V Chizhov
The conductance-based refractory density (CBRD) approach is an efficient tool for modeling interacting neuronal populations. The model describes the firing activity of a statistical ensemble of uncoupled Hodgkin-Huxley-like neurons, each receiving individual Gaussian noise and a common time-varying deterministic input. However, the approach requires experimental validation and extension to cases of distributed input signals (or input weights) among different neurons of such an ensemble. Here the CBRD model is verified by comparing with experimental data and then generalized for a lognormal (LN) distribution of the input weights...
August 17, 2017: Biological Cybernetics
https://www.readbyqxmd.com/read/28819303/automated-segmentation-of-light-sheet-fluorescent-imaging-to-characterize-experimental-doxorubicin-induced-cardiac-injury-and-repair
#5
René R Sevag Packard, Kyung In Baek, Tyler Beebe, Nelson Jen, Yichen Ding, Feng Shi, Peng Fei, Bong Jin Kang, Po-Heng Chen, Jonathan Gau, Michael Chen, Jonathan Y Tang, Yu-Huan Shih, Yonghe Ding, Debiao Li, Xiaolei Xu, Tzung K Hsiai
This study sought to develop an automated segmentation approach based on histogram analysis of raw axial images acquired by light-sheet fluorescent imaging (LSFI) to establish rapid reconstruction of the 3-D zebrafish cardiac architecture in response to doxorubicin-induced injury and repair. Input images underwent a 4-step automated image segmentation process consisting of stationary noise removal, histogram equalization, adaptive thresholding, and image fusion followed by 3-D reconstruction. We applied this method to 3-month old zebrafish injected intraperitoneally with doxorubicin followed by LSFI at 3, 30, and 60 days post-injection...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819068/rural-emergency-care-360%C3%A2-mobilising-healthcare-professionals-decision-makers-patients-and-citizens-to-improve-rural-emergency-care-in-the-province-of-quebec-canada-a-qualitative-study-protocol
#6
Richard Fleet, Gilles Dupuis, Jean-Paul Fortin, Jocelyn Gravel, Mathieu Ouimet, Julien Poitras, France Légaré
INTRODUCTION: Emergency departments (EDs) are an important safety net for rural populations. Results of our earlier studies suggest that rural Canadian hospitals have limited access to advanced imaging services and intensive care units and that patients are transferred over large distances. They also revealed significant geographical variations in rural services. In the absence of national standards, our studies raise questions about inequities in rural access to emergency services and the risks for citizens...
August 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28817239/novel-dissection-of-the-central-nervous-system-to-bridge-gross-anatomy-and-neuroscience-for-an-integrated-medical-curriculum
#7
Rebecca J Hlavac, Rachel Klaus, Kourtney Betts, Shilo M Smith, Maureen E Stabio
Medical schools in the United States continue to undergo curricular change, reorganization, and reformation as more schools transition to an integrated curriculum. Anatomy educators must find novel approaches to teach in a way that will bridge multiple disciplines. The cadaveric extraction of the central nervous system (CNS) provides an opportunity to bridge gross anatomy, neuroanatomy, and clinical neurology. In this dissection, the brain, brainstem, spinal cord, cauda equina, optic nerve/tract, and eyes are removed in one piece so that the entire CNS and its gateway to the periphery through the spinal roots can be appreciated...
August 17, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28817209/huntington-s-disease-a-clinical-review
#8
Peter McColgan, Sarah J Tabrizi
Huntington's disease (HD) is a fully penetrant neurodegenerative disease caused by a dominantly inherited CAG trinucleotide repeat expansion in the huntingtin gene on chromosome 4. In Western populations HD has a prevalence of 10.6-13.7 individuals per 100,000. It is characterised by cognitive, motor and psychiatric disturbance. At the cellular level mutant huntingtin results in neuronal dysfunction and death through a number of mechanisms, including disruption of proteostasis, transcription and mitochondrial function and direct toxicity of the mutant protein...
August 17, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28816718/double-composite-tissue-z-plasty-technique-for-anatomical-restoration-of-severe-nasal-deformity-in-secondary-unilateral-cleft-lip
#9
Jiao Wei, Tanja Herrler, Hua Xu, Qingfeng Li, Chuanchang Dai
BACKGROUND: Patients with secondary unilateral cleft lip are regularly affected by serious nasal deformities especially of the alar and nasal floor. A large number of techniques for correction have been published, but symmetrical restoration of severe nasal deformation is difficult to achieve. We propose an innovative approach for anatomical restoration for this entity of nasal deformities to achieve long-term symmetrical appearance and muscular function. METHODS: A total of 68 patients with severe nasal deformity due to secondary unilateral cleft lip underwent reconstructive surgery using a double composite tissue Z-plasty technique for anatomical restoration of cartilage, muscle, and soft tissue layers...
August 14, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28814079/measuring-the-edge-recombination-velocity-of-monolayer-semiconductors
#10
Peida Zhao, Matin Amani, Der-Hsien Lien, Geun Ho Ahn, Daisuke Kiriya, James P Mastandrea, Joel W Ager, Eli Yablonovitch, Daryl C Chrzan, Ali Javey
Understanding edge effects and quantifying their impact on the carrier properties of two-dimensional (2D) semiconductors is an essential step toward utilizing this material for high performance electronic and optoelectronic devices. WS2 monolayers patterned into disks of varying diameters are used to experimentally explore the influence of edges on the material's optical properties. Carrier lifetime measurements show a decrease in the effective lifetime, τeffective, as a function of decreasing diameter, suggesting that the edges are active sites for carrier recombination...
August 18, 2017: Nano Letters
https://www.readbyqxmd.com/read/28813806/design-of-continuous-emg-classification-approaches-towards-the-control-of-a-robotic-exoskeleton-in-reaching-movements
#11
Nerea Irastorza-Landa, Andrea Sarasola-Sanz, Eduardo Lopez-Larraz, Carlos Bibian, Parid Shiman, Niels Birbaumer, Ander Ramos-Murguialday
Myoelectric control of rehabilitation devices engages active recruitment of muscles for motor task accomplishment, which has been proven to be essential in motor rehabilitation. Unfortunately, most electromyographic (EMG) activity-based controls are limited to one single degree-of-freedom (DoF), not permitting multi-joint functional tasks. On the other hand, discrete EMG-triggered approaches fail to provide continuous feedback about muscle recruitment during movement. For such purposes, myoelectric interfaces for continuous recognition of functional movements are necessary...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28811985/incidence-impact-and-risk-factors-for-30-day-wound-complications-following-elective-adult-spinal-deformity-surgery
#12
Nathan J Lee, John I Shin, Parth Kothari, Jun S Kim, Dante M Leven, Jeremy Steinberger, Javier Z Guzman, Branko Skovrlj, John M Caridi, Samuel K Cho
STUDY DESIGN: Case-control study. OBJECTIVE: To determine the incidence, impact, and risk factors for wound complications within 30 days following elective adult spinal deformity surgery. METHODS: Current Procedural Terminology and International Classification of Diseases, Ninth Edition, diagnosis codes were used to query the database for adults who underwent spinal deformity surgery from 2010 to 2014. Patients were separated into groups of those with and without wound complications...
August 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28809462/multiple-electronic-and-structural-factors-control-cpd-and-6-4-thymine-thymine-photodimerization-in-dna-duplex
#13
Irene Conti, Lara Martinez Fernandez, Luciana Esposito, Siegfried Hofinger, Artur Nenov, Marco Garavelli, Roberto Improta
The T-T photodimerization paths leading to the formation of cyclobutane pyrimidine dimer (CPD) and 6-4 pyrimidine pyrimidone (64-PP), the two main DNA photolesions, have been resolved for a T-T step in a DNA duplex by two complementary state-of-the art quantum mechanical approaches: QM(CASPT2//CASSCF)/MM and TD-DFT/PCM. Based on the analysis of several different representative structures, we define a new-ensemble of cooperating geometrical and electronic factors (besides the distance between the reacting bonds) ruling T-T photodimerization in DNA...
August 15, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28809430/a-one-step-method-for-the-functional-and-property-modification-of-dopa-based-nanocoatings
#14
Qinghua Lyu, Jieyu Zhang, Koon Gee Neoh, Christina Li Lin Chai
Biomimetic poly(catecholamine) coatings have gained much attention in recent years due to their versatility as functional materials. Despite this, only limited methods are available to modify the function and property of poly(catecholamine) coatings, primarily through post-modification methods. Our approach reported herein provides a simple approach to the fabrication of novel functionalized poly(catecholamine) coatings. The strategy employs the copolymerization of N-Ac-3,4-dihydroxyphenylalanine methyl ester (NADOPAMe) with nucleophilic additives, giving rise to nano-coatings on various surfaces including plastic, metal, glass and polymers...
August 15, 2017: Nanoscale
https://www.readbyqxmd.com/read/28809398/precision-medicine-for-suicidality-from-universality-to-subtypes-and-personalization
#15
A B Niculescu, H Le-Niculescu, D F Levey, P L Phalen, H L Dainton, K Roseberry, E M Niculescu, J O Niezer, A Williams, D L Graham, T J Jones, V Venugopal, A Ballew, M Yard, T Gelbart, S M Kurian, A Shekhar, N J Schork, G E Sandusky, D R Salomon
Suicide remains a clear, present and increasing public health problem, despite being a potentially preventable tragedy. Its incidence is particularly high in people with overt or un(der)diagnosed psychiatric disorders. Objective and precise identification of individuals at risk, ways of monitoring response to treatments and novel preventive therapeutics need to be discovered, employed and widely deployed. We sought to investigate whether blood gene expression biomarkers for suicide (that is, a 'liquid biopsy' approach) can be identified that are more universal in nature, working across psychiatric diagnoses and genders, using larger cohorts than in previous studies...
August 15, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28807362/leg-movement-tracking-in-automatic-video-based-one-leg-stance-evaluation
#16
Jacek Kawa, Paula Stępień, Wojciech Kapko, Aleksandra Niedziela, Jarosław Derejczyk
Falls are a major risk in elder population. Early diagnosis is therefore an important step towards increasing the safety of elders. One of the common diagnostic tests is the Berg Balance Scale (BBS), consisting of 14 exercises arranged from the easiest (sitting-to-standing) to the most demanding (one-leg stance). In this study a novel approach to the automatic assessment of the time in which the patient can remain in the one-leg stance position without loosing balance is introduced. The data is collected using a regular video camera...
August 3, 2017: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/28805860/synthesis-of-n-doped-graphene-quantum-dots-by-pulsed-laser-ablation-with-diethylenetriamine-deta-and-their-photoluminescence
#17
S R M Santiago, T N Lin, C H Chang, Y A Wong, C A J Lin, C T Yuan, J L Shen
We report a facile, fast, and one-step approach to prepare N-doped graphene quantum dots (GQDs) using pulsed laser ablation with diethylenetriamine (DETA). The synthesized N-doped GQDs with an average size of about 3.4 nm and an N/C atomic ratio of 26% have been demonstrated. Compared to pristine GQDs, the N-doped GQDs emit enhanced photoluminescence (PL) with a factor as high as 66, originated from the enhanced densities of pyridinic and graphitic N. The temperature-dependent PL of the N-doped GQDs was studied from cryogenic to room temperature...
August 14, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28804809/therapeutic-patient-education-in-cancer-pain-management-from-practice-to-research-proposals-and-strategy-of-the-french-effadol-program
#18
Virginie Prevost, Bénédicte Clarisse, Natacha Heutte, Alexandra Leconte, Cécile Bisson, Rachel Bignon, Sonia Cauchin, Maryline Feuillet, Sylvie Gehanne, Maud Gicquère, Marie-Christine Grach, Cyril Guillaumé, Christine Le Gal, Joelle Le Garrec, Franck Lecaer, Isabelle Lepleux, Anne-Laure Millet, Marie-Claude Ropartz, Nathalie Roux, Virith Sep Hieng, Carole Van Delook, Aline Le Chevalier, Claire Delorme
In the field of cancer pain, therapeutic patient education (TPE) allows patients to develop skills to better manage their pain. In the Lower Normandy region of France, the management of pain is based on networking, thus allowing proximity and accessibility for all concerned. We have thus designed and initiated a broad five-stage research program that includes the following: (1) training for caregivers in TPE; (2) identifying the educational expectations of patients and their relatives with regard to cancer pain; (3) the design of a TPE program; (4) the evaluation of its quality; and (5) the evaluation of its effectiveness by comparative randomization...
August 13, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28803650/lipid-determination-in-bone-marrow-and-mineralized-bone-tissue-from-sample-preparation-to-improved-high-performance-thin-layer-and-liquid-chromatographic-approaches
#19
Alexandrine During
In view of their key roles in the bone physiology (e.g., in the biomineralization process) and their potential implication in bone pathologies, an approach to study lipids in situ is needed. The aim of the present paper is to propose an original procedure to characterize lipids in both bone marrow (BM) and mineralized tissue (MT) compartments, taking into consideration sample preparation, lipid extraction and analytical issues, when using small sample size (≤ 0.5g of rat femurs). The potential contamination of the MT by marrow lipids and the poor accessibility of certain lipids from the MT - two major issues in bone handling - were taking care, respectively by performing two cleaning steps after BM removal and by adding a demineralization step to the overall lipid extraction protocol...
August 3, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28799403/combined-4-component-and-relativistic-pseudopotential-study-of-tho-for-the-electron-electric-dipole-moment-search
#20
L V Skripnikov
A precise theoretical study of the electronic structure of heavy atom diatomic molecules is of key importance to interpret the experiments in the search for violation of time-reversal (T) and spatial-parity (P) symmetries of fundamental interactions in terms of the electron electric dipole moment, eEDM, and dimensionless constant, kT,P, characterizing the strength of the T,P-odd pseudoscalar-scalar electron-nucleus neutral current interaction. The ACME collaboration has recently improved limits on these quantities using a beam of ThO molecules in the electronic H(3)Δ1 state [J...
December 7, 2016: Journal of Chemical Physics
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