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https://www.readbyqxmd.com/read/25719487/glp-1-and-exendin-4-for-imaging-endocrine-pancreas-a-review-labelled-glucagon-like-peptide-1-analogues-past-present-and-future
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A Hubalewska-Dydejczyk, A Sowa-Staszczak, M Tomaszuk, A StefaƄska
Glucagon-like peptide 1 (GLP-1) receptors expression has been found on many types of cancer cells. In case of benign insulinoma the density of those receptors is even higher than the density of somatostatin receptors. This article presents the results of clinical trials proving the utility of GLP-1 receptors imaging. Scintigraphy or positron emission tomography with the use of GLP-1 analogues labelled with appropriate radioisotopes (111In, 99mTc, 68Ga, 18F or 64Cu) seem to be superior compared with other available techniques in diagnosis of hardly detectable benign insulinoma...
June 2015: Quarterly Journal of Nuclear Medicine and Molecular Imaging
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