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Mechanical Circulatory Support

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https://www.readbyqxmd.com/read/29677081/changes-in-pediatric-heart-transplant-hospitalization-costs-over-time
#1
Justin Godown, Cary Thurm, Matt Hall, Jonathan H Soslow, Brian Feingold, Bret A Mettler, Andrew H Smith, David W Bearl, Debra A Dodd
BACKGROUND: Despite significant changes in the past decade for children undergoing heart-transplantation, including the evolution of mechanical circulatory support and increasing patient complexity, costs and resource utilization have not been reassessed. We sought to utilize a novel linkage of clinical-registry and administrative data to examine changes in hospitalization costs over time in this population. METHODS: We identified all pediatric heart transplant recipients in a unique linked PHIS/SRTR dataset (2002-2016)...
April 19, 2018: Transplantation
https://www.readbyqxmd.com/read/29674141/trends-in-utilization-of-mechanical-circulatory-support-in-patients-hospitalized-after-out-of-hospital-cardiac-arrest
#2
Nileshkumar J Patel, Nish Patel, Bhaskar Bhardwaj, Harsh Golwala, Varun Kumar, Varunsiri Atti, Shilpkumar Arora, Smit Patel, Nilay Patel, Gabriel A Hernandez, Apurva Badheka, Carlos E Alfonso, Mauricio G Cohen, Deepak L Bhatt, Navin K Kapur
OBJECTIVE: This study sought to examine the trends and predictors of mechanical circulatory support (MCS) use in patients hospitalized after out-of-hospital cardiac arrest (OHCA). BACKGROUND: There is a paucity of data regarding MCS use in patients hospitalized after OHCA. METHODS: We conducted an observational analysis of MCS use in 960,428 patients hospitalized after OHCA between January 2008 and December 2014 in the Nationwide Inpatient Sample database...
April 16, 2018: Resuscitation
https://www.readbyqxmd.com/read/29673652/the-checklist-manifesto-for-mechanical-circulatory-support-targeting-anti-coagulation-efficiency
#3
EDITORIAL
Patricia A Uber, Hector O Ventura
No abstract text is available yet for this article.
May 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29673634/the-right-tool-for-the-right-job-bridging-a-failing-fontan-to-transplant
#4
Kyle W Riggs, Angela Lorts, Chet R Villa, James Tweddell, Roosevelt Bryant, David Ls Morales
Mechanical circulatory support and heart transplantation are both becoming increasingly common in Fontan patients as this growing cohort of patients is reaching young adulthood. Though device placement may present challenges, the new focus is on selecting the correct cannulation sites and devices at the correct time in order to successfully bridge these challenging patients to heart transplant. Herein, we report the use of multiple mechanical circulatory support strategies tailored to the clinical setting which culminated in 130 days of support prior to cardiac transplantation in a young adult with a failing Fontan circulation...
April 16, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29667251/animal-models-for-pediatric-mechanical-circulatory-support-research-at-penn-state-health
#5
EDITORIAL
Jenelle M Izer, Ronald P Wilson, Joseph B Clark, John L Myers, William W Weiss, Akif Ündar
No abstract text is available yet for this article.
April 2018: Artificial Organs
https://www.readbyqxmd.com/read/29664407/mechanical-circulatory-support-device-utilization-and-heart-transplant-waitlist-outcomes-in-patients-with-restrictive-and-hypertrophic-cardiomyopathy
#6
Lakshmi Sridharan, Brian Wayda, Lauren K Truby, Farhana Latif, Susan Restaino, Koji Takeda, Hiroo Takayama, Yoshifumi Naka, Paolo C Colombo, Mathew Maurer, Maryjane A Farr, Veli K Topkara
BACKGROUND: Patients with restrictive cardiomyopathy (RCM) and hypertrophic cardiomyopathy (HCM) generally are considered poor candidates for mechanical circulatory support devices (MCSDs) and often not able to be bridged mechanically to heart transplantation. This study characterized MCSD utilization and transplant waitlist outcomes in patients with RCM/HCM under the current allocation system and discusses changes in the era of the new donor allocation system. METHODS AND RESULTS: Patients waitlisted from 2006 to 2016 in the United Network for Organ Sharing registry were stratified by RCM/HCM versus other diagnoses...
March 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29655880/efficacy-and-safety-of-the-heartmate-percutaneous-heart-pump-during-high-risk-percutaneous-coronary-intervention-from-the-shield-i-trial
#7
Dariusz Dudek, Adrian Ebner, Robert Sobczyński, Jarosław Trębacz, Boris Vesga, Juan Granada, Marian Zembala, Adam Witkowski, Nicolas M Van Mieghem, Poornima Sood, Andrzej Ochała, Artur Dziewierz, Krzysztof Żmudka
This study aimed to evaluate the use of the HeartMate percutaneous heart pump, a catheter-based axial flow pump designed to provide partial left ventricular support, in patients who underwent high-risk percutaneous coronary intervention (PCI). Patients who are hemodynamically unstable, or at risk of being hemodynamically unstable, while undergoing PCI may require mechanical circulatory support. Fifty high-risk patients were enrolled in a prospective, nonrandomized, multicenter, open-label trial. Primary end points were freedom from hemodynamic compromise during PCI and a composite measure of major adverse events...
March 13, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29655828/venoarterial-extracorporeal-membrane-oxygenation-in-cardiogenic-shock
#8
REVIEW
Mary E Keebler, Elias V Haddad, Chun W Choi, Stuart McGrane, Sandip Zalawadiya, Kelly H Schlendorf, D Marshall Brinkley, Matthew R Danter, Mark Wigger, Jonathan N Menachem, Ashish Shah, JoAnn Lindenfeld
Venoarterial extracorporeal membrane oxygenation has emerged as a viable treatment for patients in cardiogenic shock with biventricular failure and pulmonary dysfunction. Advances in pump and oxygenator technology, cannulation strategies, patient selection and management, and durable mechanical circulatory support have contributed to expanded utilization of this technology. However, challenges remain that require investigation to improve outcomes.
April 5, 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/29643259/cerebrovascular-accidents-during-mechanical-circulatory-support-new-predictors-of-ischemic-and-hemorrhagic-strokes-and-outcome
#9
Saef Izzy, Daniel B Rubin, Firas S Ahmed, Feras Akbik, Simone Renault, Katelyn W Sylvester, Henrikas Vaitkevicius, Jennifer A Smallwood, Michael M Givertz, Steven K Feske
BACKGROUND AND PURPOSE: Left ventricular assist devices (LVADs) have emerged as an effective treatment for patients with advanced heart failure refractory to medical therapy. Post-LVAD strokes are an important cause of morbidity and reduced quality of life. Data on risks that distinguish between ischemic and hemorrhagic post-LVAD strokes are limited. The aim of this study was to determine the incidence of post-LVAD ischemic and hemorrhagic strokes, their association with stroke risk factors, and their effect on mortality...
April 11, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29643128/effects-of-impella-on-coronary-perfusion-in-patients-with-critical-coronary-artery-stenosis
#10
Mohammad Alqarqaz, Mir Basir, Khaldoon Alaswad, William O'Neill
BACKGROUND: Mechanical circulatory support devices are used to maintain hemodynamic stability during high-risk percutaneous coronary interventions. Little is known on the effects of such devices on coronary hemodynamics in patients with significant coronary stenosis. We sought to investigate whether mechanical circulatory support in the form of Impella (Abiomed Inc, Danvers, MA) can improve coronary hemodynamics in the presence of a critical coronary stenosis. METHODS AND RESULTS: We examined coronary perfusion pressures and coronary pressure distal to a critical stenosis using a coronary pressure wire in 11 patients (12 coronary lesions) undergoing high-risk percutaneous coronary interventions with the use of mechanical circulatory support...
April 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29629994/the-achilles-heel-of-left-ventricular-assist-device-therapy-right-ventricle
#11
Neel K Ranganath, Deane E Smith, Nader Moazami
PURPOSE OF REVIEW: Many patients suffer from either persistent right ventricular failure (RVF) at the time of left ventricular assist device (LVAD) or have ongoing symptoms consistent with RVF during chronic mechanical circulatory support. The lack of long-term right ventricular assist devices (RVADs) has limited the impact that mechanical circulatory support can provide to patients with biventricular failure. We aim to review the entire spectrum of RVF in patients receiving LVADs and reflect on why this entity remains the Achilles' heel of LVAD therapy...
April 7, 2018: Current Opinion in Organ Transplantation
https://www.readbyqxmd.com/read/29628145/percutaneous-biventricular-impella-support-in-therapy-refractory-cardiogenic-shock
#12
Cheng-Ying Chiu, Robert Hättasch, Damaris Praeger, Fabian Knebel, Karl Stangl, Ivan Diaz Ramirez, Henryk Dreger
INTRODUCTION: Percutaneous mechanical circulatory support systems have increasingly been adopted as a bail out strategy in patients with cardiogenic shock. Since studies showed mostly mixed results, however, the use of support systems remains a case by case decision. CASE: Here, we report on a case of therapy-refractory cardiogenic shock due to acute myocardial infarction treated with percutaneous right and left ventricular assist devices (Impella RP and CP). CONCLUSION: Due to myocardial stunning, even patients with fulminant cardiogenic shock have the potential for full recovery...
April 5, 2018: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/29628136/balancing-decisions-in-mechanical-circulatory-support-it-s-all-in-the-timing
#13
EDITORIAL
Christopher S Hayward
No abstract text is available yet for this article.
February 27, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29624172/mechanical-circulatory-support-the-last-resort-in-cardiogenic-shock
#14
Holger Thiele, Steffen Desch, Suzanne de Waha
No abstract text is available yet for this article.
April 6, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29623530/novel-insights-and-treatment-strategies-for-right-heart-failure
#15
REVIEW
Weiqin Lin, Ai-Ling Poh, W H Wilson Tang
PURPOSE OF REVIEW: The function of the right ventricle (RV) is intimately linked to its preload (systemic volume status) and afterload (pulmonary vasculature). In this review, we explore current knowledge in RV physiology, RV function assessment, causes of right heart failure (RHF), and specific treatment strategies for RHF. RECENT FINDINGS: We examine the evidence behind new pharmacological therapies available, such as macitentan and riociguat in the treatment of specific etiologies of RHF...
April 6, 2018: Current Heart Failure Reports
https://www.readbyqxmd.com/read/29623383/-mechanical-circulatory-support-in-terminal-heart-failure
#16
REVIEW
M Derwall, A Moza, A Brücken
BACKGROUND: After exhaustion of all conservative measures in the treatment of acute and chronic heart insufficiency, there is the possibility to temporarily or permanently support or replace the pump performance of the heart by mechanical circulatory support (MCS) systems. OBJECTIVE: Presentation of the most important cardiac support systems for intensive care medicine, their indications and important risk factors. MATERIAL AND METHODS: Critical review of device manufacturer's specifications, current research and expert opinions...
April 5, 2018: Der Anaesthesist
https://www.readbyqxmd.com/read/29623169/mechanical-circulatory-support-in-high-risk-percutaneous-coronary-intervention
#17
REVIEW
Bhuvnesh Aggarwal, Wahaj Aman, Omar Jeroudi, Neal S Kleiman
Due to advancing age and increasing comorbidities, the current population has a higher incidence of complex coronary artery disease, often without surgical options for revascularization. In this setting, hemodynamic support devices are an important adjunct in the interventionist's toolbox as they allow for a safer, more effective procedure. The following paper reviews the indications of various available mechanical support devices, highlights their clinical data and technical parameters, and offers a practical approach towards appropriate patient and device selection...
January 2018: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/29620610/applications-of-implantable-hemodynamic-monitoring-in-the-setting-of-durable-mechanical-circulatory-support
#18
Francis D Pagani
No abstract text is available yet for this article.
March 15, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29617917/management-of-hypercalcaemia-induced-heart-failure-using-mechanical-circulatory-support
#19
Katharina Knoll, Volkhard Kurowski, Heribert Schunkert, Hendrik B Sager
Acute heart failure is associated with high morbidity and mortality. Heart failure is caused by various conditions, including electrolyte imbalances. We report a rare case of hypercalcaemia-induced acute heart failure complicated by cardiogenic shock. Mechanical circulatory support was used successfully in this patient until calcium homeostasis was restored.
March 30, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29608506/the-physiological-rationale-for-incorporating-pulsatility-in-continuous-flow-left-ventricular-assist-devices
#20
Liza Grosman-Rimon, Filio Billia, Jeremy Kobulnik, Stacey Pollock Bar-Ziv, David Z Cherney, Vivek Rao
Over the past few decades, left ventricular assist device (LVAD) support has extended the lives of many patients with end-stage heart failure. The most common devices are continuous-flow (CF) LVADs. The use of the CF-LVADs has required that clinicians learn the physiological and clinical consequences of long-term continuous blood flow. While this alteration in the normal physiology still offers advantages from mechanical circulatory support, the lack of pulsatility may also increase the likelihood of adverse events...
March 30, 2018: Cardiology in Review
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