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Mechanical Circulatory Support

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https://www.readbyqxmd.com/read/29029180/cerebral-strokes-in-children-on-intracorporeal-ventricular-assist-devices-analysis-of-the-euromacs-registry
#1
Martin Schweiger, Oliver Miera, Theo M M H de By, Michael Hübler, Felix Berger, Mustafa Özbaran, Antonio Loforte, Burkhardt Seifert, Gaetano Gargiulo, Jan Gummert, Paul Mohacsi
OBJECTIVES: Little is known about cerebral strokes in paediatric patients supported by intracorporeal continuous-flow ventricular assist devices. METHODS: We retrospectively investigated patients younger than 19 years of age who were treated with an intracorporeal continuous-flow ventricular assist device in the European Registry for Patients with Mechanical Circulatory Support (EUROMACS) database. The patients were stratified by body surface area in Group 1 [<1...
September 25, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29029117/the-european-registry-for-patients-with-mechanical-circulatory-support-euromacs-of-the-european-association-for-cardio-thoracic-surgery-eacts-second-report
#2
Theo M M H de By, Paul Mohacsi, Brigitta Gahl, Armin Zittermann, Thomas Krabatsch, Finn Gustafsson, Pascal Leprince, Bart Meyns, Ivan Netuka, Kadir Caliskan, Evaristo Castedo, Francesco Musumeci, André Vincentelli, Roland Hetzer, Jan Gummert
OBJECTIVES: The European Registry for Patients with Mechanical Circulatory Support (EUROMACS) was founded in Berlin, Germany. EUROMACS is supported fully by the European Association for Cardio-Thoracic Surgery (EACTS) and, since 2014, has functioned as a committee of the EACTS. The purpose of having the EUROMACS as a part of the EACTS is to accumulate clinical data related to long-term mechanical circulatory support for scientific purposes and to publish annual reports. METHODS: Participating hospitals contributed surgical and cardiological pre-, peri- and long-term postoperative data of mechanical circulatory support implants to the registry...
September 29, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29028076/intestinal-probiotics-in-relieving-clinical-symptoms-of-severe-hand-foot-and-mouth-disease-and-potential-mechanism-analysis
#3
F Zhu, Z Jiang, H-W Li
OBJECTIVE: In this prospective cohort study, the efficacy and action mechanism of an intestinal probiotic formulation, Golden Bifid, in severe hand, foot, and mouth disease (HFMD) were determined in 63 consecutively admitted patients successfully treated in the Pediatrics Emergency Department of our hospital. PATIENTS AND METHODS: All patients had a persistent fever; 43 patients had rashes on hands, feet, crissum, and hips; and 45 patients had neurological signs and symptoms...
September 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29022269/experimental-evidences-supporting-training-induced-benefits-in-spontaneously-hypertensive-rats
#4
Gustavo S Masson, Lisete C Michelini
It is well known that chronic hypertension is accompanied by several functional deficits in the central nervous system and peripheral tissues, most of which are corrected by exercise training. However, the biological mechanisms underlying these effects are not yet well understood. In the present chapter we summarize recent experimental evidence on cellular/molecular mechanisms supporting not only the deleterious effects of hypertension on autonomic control and peripheral circulatory deficits, but also their reversion by low to moderate aerobic exercise training...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29021348/early-right-ventricular-assist-device-use-in-patients-undergoing-continuous-flow-left-ventricular-assist-device-implantation-incidence-and-risk-factors-from-the-interagency-registry-for-mechanically-assisted-circulatory-support
#5
Michael S Kiernan, E Wilson Grandin, Marshall Brinkley, Navin K Kapur, Duc Thinh Pham, Robin Ruthazer, J Eduardo Rame, Pavan Atluri, Edo Y Birati, Guilherme H Oliveira, Francis D Pagani, James K Kirklin, David Naftel, Robert L Kormos, Jeffrey J Teuteberg, David DeNofrio
BACKGROUND: To investigate preimplant risk factors associated with early right ventricular assist device (RVAD) use in patients undergoing continuous-flow left ventricular assist device (LVAD) surgery. METHODS AND RESULTS: Patients in the Interagency Registry for Mechanically Assisted Circulatory Support who underwent primary continuous-flow-LVAD surgery were examined for concurrent or subsequent RVAD implantation within 14 days of LVAD. Risk factors for RVAD implantation and the combined end point of RVAD or death within 14 days of LVAD were assessed with stepwise logistic regression...
October 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29020341/percutaneous-short-term-active-mechanical-support-devices-in-cardiogenic-shock-a-systematic-review-and-collaborative-meta-analysis-of-randomized-trials
#6
Holger Thiele, Alexander Jobs, Dagmar M Ouweneel, Jose P S Henriques, Melchior Seyfarth, Steffen Desch, Ingo Eitel, Janine Pöss, Georg Fuernau, Suzanne de Waha
Aims: Evidence on the impact on clinical outcome of active mechanical circulatory support (MCS) devices in cardiogenic shock (CS) is scarce. This collaborative meta-analysis of randomized trials thus aims to investigate the efficacy and safety of percutanzeous active MCS vs. control in CS. Methods and results: Randomized trials comparing percutaneous active MCS to control in patients with CS were identified through searches of medical literature databases. Risk ratios (RR) and 95% confidence intervals (95% CI) were calculated to analyse the primary endpoint of 30-day mortality and device-related complications including bleeding and leg ischaemia...
July 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29020331/mechanical-circulatory-support-harm-without-benefit-fascinated-by-devices-cardiologists-may-lose-common-sense
#7
Petr Widimsky
No abstract text is available yet for this article.
July 21, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28993843/in-hospital-mortality-after-acute-stemi-in-patients-undergoing-primary-pci
#8
M Ali, S A Lange, T Wittlinger, G Lehnert, A G Rigopoulos, M Noutsias
BACKGROUND: Acute myocardial infarction (AMI) is the main cause of global and in-hospital mortality in patients with cardiovascular diseases. We aimed to examine the association between the coronary artery involved and the in-hospital mortality in patients who underwent primary percutaneous coronary intervention (pPCI) after ST segment elevation myocardial infarction (STEMI). METHODS: The in-hospital mortality of STEMI patients who underwent pPCI was assessed at the Department of Cardiology, Harzklinik Goslar, Germany, which has no access to immediate mechanical circulatory support (MCS), between 2013 and 2017...
October 9, 2017: Herz
https://www.readbyqxmd.com/read/28987857/intracranial-hemorrhage-in-patients-with-durable-mechanical-circulatory-support-devices-institutional-review-and-proposed-treatment-algorithm
#9
Wyatt L Ramey, Robyn L Basken, Christina M Walter, Zain Khalpey, G Michael Lemole, Travis M Dumont
OBJECTIVE: Spontaneous intracranial hemorrhage (ICH) is frequently managed in neurosurgery. Patients with durable mechanical circulatory support devices, including total artificial hearts (TAHs) and left ventricular assist devices (LVADs) are often encountered in the setting of ICH. While durable mechanical circulatory support devices have improved survival and quality of life for patients with advanced heart failure, ICH is one of the most feared complications following LVAD and TAH implantation...
October 4, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28986059/the-day-of-the-week-and-acute-heart-failure-admissions-relationship-with-acute-myocardial-infarction-30-day-readmission-rate-and-in-hospital-mortality
#10
Mahek Shah, Soumya Patnaik, Brijesh Patel, Shilpkumar Arora, Nilay Patel, Sopan Lahewala, Vincent M Figueredo, Matthew W Martinez, Larry Jacobs
BACKGROUND: In-hospital care may be constrained during the weekend due to lesser resources. Impact on outcomes of weekend versus weekday care in congestive heart failure (HF) needs further study. METHODS: Admissions with a primary diagnosis of HF using ICD-9CM codes were studied. 22,287 HF-admissions from Einstein Medical Center (2003-2013) and 2,248,482 HF-admissions from the 2002-2012 Nationwide Inpatient Sample (NIS) were analyzed separately. Primary outcomes were 30-day HF-readmission and in-hospital mortality...
September 29, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28984061/management-of-patients-with-cardiogenic-shock-on-temporary-mechanical-circulatory-support-urgent-transplantation-or-on-to-the-next-pump
#11
EDITORIAL
Finn Gustafsson
No abstract text is available yet for this article.
October 6, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28980299/extracellular-vesicles-in-post-infarct-ventricular-remodelling
#12
Aleksandra Gasecka, Edwin van der Pol, Rienk Nieuwland, Ewa Stępień
Post-infarct left ventricle remodelling (LVR) is defined as the structural and functional changes of the myocardium occurring after acute myocardial infarction (AMI) and leading to the loss of contractile tissue and subsequently to post-infarct heart failure (HF). LVR affects 30% of patients after AMI, deteriorating the prognosis. At present, no clinical, biochemical and imaging parameters predict which patients will develop LVR and progress to HF. Despite recent progress in pharmacological treatment, mechanical circulatory support and multidisciplinary team management, none of the available treatments entirely prevent, inhibit or reverse LVR...
October 5, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28975854/clinical-application-of-intra-aortic-balloon-counterpulsation-in-high-risk-patients-undergoing-cardiac-surgery
#13
Dengbang Hou, Feng Yang, Xiaotong Hou
The intra-aortic balloon pump (IABP) has been the most commonly used mechanical circulatory support device for nearly five decades. In theory, the IABP can increase the blood and oxygen supply of the coronary artery by increasing the diastolic pressure in the aortic root when the balloon is inflated and reduce left ventricular afterload by rapidly deflating the balloon during the systolic phase. Therefore, some researchers put forward the idea of preoperative prophylactic use of an IABP, which has been frequently performed in high-risk patients undergoing elective percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG)...
October 1, 2017: Perfusion
https://www.readbyqxmd.com/read/28965736/second-annual-pediatric-interagency-registry-for-mechanical-circulatory-support-pedimacs-report-pre-implant-characteristics-and-outcomes
#14
Elizabeth D Blume, Christina VanderPluym, Angela Lorts, J Timothy Baldwin, Joseph W Rossano, David L S Morales, Ryan S Cantor, Marissa A Miller, James D St Louis, Devin Koehl, David L Sutcliffe, Pirooz Eghtesady, James K Kirklin, David N Rosenthal
BACKGROUND: Expanded use of pediatric ventricular assist devices (VADs) has decreased mortality in children awaiting heart transplantation. Pediatric Interagency Registry for Mechanical Circulatory Support (Pedimacs), a National Heart, Lung, and Blood Institute-sponsored North American database, provides a platform to understand this emerging population. METHODS: Between September 2012 and September 2016, patients aged younger than 19 years who underwent VAD implantation were enrolled in Pedimacs...
July 4, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28962495/is-there-a-role-for-upper-extremity-intra-aortic-balloon-counterpulsation-as-a-bridge-to-recovery-or-a-bridge-to-transplant-in-the-treatment-of-end-stage-heart-failure
#15
Nnamdi Nwaejike, Andre Y Son, Carmelo A Milano, Mani A Daneshmand
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was: Is there a role for upper-extremity intra-aortic balloon pump counterpulsation (UE-IABP) in the treatment of end-stage heart failure? Altogether 230 papers were found using the reported search, of which 6 papers represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated...
October 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28958345/intermacs-analysis-of-stroke-during-support-with-continuous-flow-left%C3%A2-ventricular-assist-devices-risk-factors-and-outcomes
#16
Deepak Acharya, Renzo Loyaga-Rendon, Charity J Morgan, Kara A Sands, Salpy V Pamboukian, Indranee Rajapreyar, William L Holman, James K Kirklin, José A Tallaj
OBJECTIVES: This study sought to evaluate predictors of stroke during left ventricular assist device (LVAD) support from data available prior to implantation, and quantify stroke-related morbidity and mortality. BACKGROUND: Stroke is a major complication after LVAD. Pre-implant factors that influence stroke are not well understood. METHODS: We evaluated all patients in INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) who were implanted with continuous flow LVADs from May 1, 2012, to March 31, 2015...
October 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28953199/the-utility-of-a-wireless-implantable-hemodynamic-monitoring-system-in-patients-requiring-mechanical-circulatory-support
#17
David S Feldman, Nader Moazami, Philip B Adamson, Juliane Vierecke, Nir Raval, Satya Shreenivas, Barry M Cabuay, Javier Jimenez, William T Abraham, John B O'Connell, Yoshifumi Naka
Proper timing of left ventricular assist device (LVAD) implantation in advanced heart failure patients is not well established and is an area of intense interest. In addition, optimizing LVAD performance after implantation remains difficult and represents a significant clinical need. Implantable hemodynamic monitoring systems may provide physicians with the physiologic information necessary to improve the timing of LVAD implantation as well as LVAD performance when compared with current methods. The CardioMEMS Heart sensor Allows for Monitoirng of Pressures to Improve Outcomes in NYHA Class III heart failure patients (CHAMPION) Trial enrolled 550 previously hospitalized patients with New York Heart Association (NYHA) class III heart failure...
September 25, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28951661/mechanical-circulatory-support-as-a-bridge-to-lung-transplantation-a-single-canadian-institution-review
#18
Katie Kinaschuk, Sabin J Bozso, Kieran Halloran, Ali Kapasi, Kathy Jackson, Jayan Nagendran
BACKGROUND: Lung transplant (LTx) waitlists continue to grow internationally. Consequently, more patients are progressing to require mechanical circulatory support (MCS) as a bridge to transplantation (BTT). MCS strategies include interventional lung assist (iLA) and venovenous (VV) and venoarterial (VA) extracorporeal membrane oxygenation (ECMO). We review our series of patients bridged with MCS while listed for LTx. METHODS: All consecutive patients, listed for LTx requiring MCS as a BTT at the University of Alberta from 2004 to 2015, were included...
2017: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/28949079/clinical-outcomes-of-temporary-mechanical-circulatory-support-as-a-direct-bridge-to-heart-transplantation-a-nationwide-spanish-registry
#19
Eduardo Barge-Caballero, Luis Almenar-Bonet, Francisco Gonzalez-Vilchez, José L Lambert-Rodríguez, José González-Costello, Javier Segovia-Cubero, María A Castel-Lavilla, Juan Delgado-Jiménez, Iris P Garrido-Bravo, Diego Rangel-Sousa, Manuel Martínez-Sellés, Luis De la Fuente-Galan, Gregorio Rábago-Juan-Aracil, Marisa Sanz-Julve, Daniela Hervás-Sotomayor, Sonia Mirabet-Pérez, Javier Muñiz, María G Crespo-Leiro
BACKGROUND: In Spain, listing for high-urgent heart transplantation is allowed for critically ill candidates not weanable from temporary mechanical circulatory support (T-MCS). We sought to analyse the clinical outcomes of this strategy. METHODS AND RESULTS: We conducted a case-by-case, retrospective review of clinical records of 291 adult patients listed for high-urgent heart transplantation under temporary devices from 2010 to 2015 in 16 Spanish institutions. Survival after listing and adverse clinical events were studied...
September 26, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28948385/delayed-sternal-closure-does-not-reduce-complications-associated-with-coagulopathy-and-right-ventricular-failure-after-left-ventricular-assist-device-implantation
#20
Roh Yanagida, Navin Rajagopalan, Daniel L Davenport, Thomas A Tribble, Mark A Bradley, Charles W Hoopes
Delayed sternal closure (DSC) is occasionally adopted after implantation of left ventricular assist device (LVAD). Recent studies suggest that DSC be used for high risk group of patients with coagulopathy, hemodynamic instability or right ventricular failure. However, whether DSC is efficacious for bleeding complication or right ventricular failure is not known. This study is single center analysis of 52 patients, who underwent LVAD implantation. Of those 52 patients, 40 consecutive patients underwent DSC routinely...
September 25, 2017: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
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