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https://www.readbyqxmd.com/read/28338880/the-yield-and-feasibility-of-integrated-screening-for-tb-diabetes-and-hiv-in-four-public-hospitals-in-ethiopia
#1
Degu Jerene, Nebiyu Hiruy, Ilili Jemal, Wondimu Gebrekiros, Tadesse Anteneh, Dereje Habte, Muluken Melese, Pedro Suarez, Gloria Sangiwa
Background: Our objective was to demonstrate the feasibility of integrated care for TB, HIV and diabetes mellitus (DM) in a pilot project in Ethiopia. Methods: Healthcare workers in four hospitals screened patients with TB for HIV and DM; patients with HIV for DM and TB; and patients with DM for TB. Fasting and random plasma glucose (RPG) tests were used to confirm the diagnosis of DM. We used screening checklists for TB and DM, and additional risk scoring criteria to identify patients at risk of DM...
March 1, 2017: International Health
https://www.readbyqxmd.com/read/28306601/assessing-the-impact-of-diabetes-mellitus-on-donor-corneal-endothelial-cell-density
#2
Chase A Liaboe, Benjamin T Aldrich, Pamela C Carter, Jessica M Skeie, Kimberlee A Burckart, Gregory A Schmidt, Cynthia R Reed, M Bridget Zimmerman, Mark A Greiner
PURPOSE: To quantify changes in endothelial cell density (ECD) of donor corneal tissue in relation to the presence or absence of a medical history of diabetes mellitus diagnosis, treatment, and complications. METHODS: A retrospective review was performed for all corneas collected at Iowa Lions Eye Bank between January 2012 and December 2015. For purposes of analysis, donor corneas were divided into 4 groups: nondiabetic, non-insulin-dependent diabetic, insulin-dependent diabetic without medical complications due to diabetes, and insulin-dependent diabetic with medical complications due to diabetes...
May 2017: Cornea
https://www.readbyqxmd.com/read/28231380/perioperative-medications-for-preventing-temporarily-increased-intraocular-pressure-after-laser-trabeculoplasty
#3
REVIEW
Linda Zhang, Jennifer S Weizer, David C Musch
BACKGROUND: Glaucoma is the international leading cause of irreversible blindness. Intraocular pressure (IOP) is the only currently known modifiable risk factor; it can be reduced by medications, incisional surgery, or laser trabeculoplasty (LTP). LTP reduces IOP by 25% to 30% from baseline, but early acute IOP elevation after LTP is a common adverse effect. Most of these IOP elevations are transient, but temporarily elevated IOP may cause further optic nerve damage, worsening of glaucoma requiring additional therapy, and permanent vision loss...
February 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28219918/clinical-outcomes-of-remote-ischemic-preconditioning-prior-to-cardiac-surgery-a-meta-analysis-of-randomized-controlled-trials
#4
REVIEW
Brian Pierce, Indra Bole, Vaiibhav Patel, David L Brown
BACKGROUND: Multiple randomized controlled trials of remote ischemic preconditioning (RIPC) prior to cardiac surgery have failed to demonstrate clinical benefit. The aim of this updated meta-analysis was to evaluate the effect of RIPC on outcomes following cardiac surgery. METHODS AND RESULTS: Searches of PubMed, Cochrane, EMBASE, and Web of Science databases were performed for 1970 to December 13, 2015. Randomized controlled trials comparing RIPC with a sham procedure prior to cardiac surgery performed with cardiopulmonary bypass were assessed...
February 20, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28216912/pregnancy-outcomes-and-maternal-and-perinatal-complications-of-pregnancies-following-in-vitro-fertilization-intracytoplasmic-sperm-injection-using-own-oocytes-donor-oocytes-and-vitrified-embryos-a-prospective-follow-up-study
#5
Manish Banker, Vidhisha Mehta, Dipesh Sorathiya, Mira Dave, Sandeep Shah
BACKGROUND: Several global studies have assessed maternal and perinatal outcomes and complications with the type of embryo transfer (ET) following in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). The present study assessed the incidence of maternal and perinatal outcomes and complications following IVF/ICSI associated with the type of embryo transferred. METHODOLOGY: A total of 2112 ETs were performed in 2092 female patients aged 21-50 years between January 1 and December 31, 2014 (Group A: Fresh ET using self-oocytes: 691; Group B: Fresh ET using donor oocytes: 810; and Group C: Thaw ET using vitrified-warmed embryos: 611)...
October 2016: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/28091758/-deaths-from-propofol-abuse-survey-of-institutes-of-forensic-medicine-in-germany-austria-and-switzerland
#6
C Maier, J Iwunna, M Tsokos, F Mußhoff
Previous references suggesting a high mortality of propofol addiction in medical personnel were mostly based on surveys of the heads of medical departments or case reports; therefore, a questionnaire was sent to 48 forensic medicine departments in Germany, Austria and Switzerland concerning the number of autopsies carried out between 2002-2112 on medical personnel with the suspicion of abuse of propofol or other analgesics. The response rate was 67%. In 16 out of the 32 responding departments 39 deaths (27 males) were observed with previous connections to anesthesiology, intensive care or emergency departments of which 22 were physicians, 13 nurses, 2 other personnel and 2 were unknown...
February 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28072479/reference-values-for-sonographically-estimated-fetal-weight-in-twin-gestations-stratified-by-chorionicity-a-single-center-study
#7
Rinat Gabbay-Benziv, Sarah Crimmins, Stephen A Contag
OBJECTIVES: To determine reference values for sonography-based estimated fetal weight (EFW) in twin gestations in one single tertiary medical center in the United States. METHODS: A retrospective longitudinal analysis of EFW evaluations of fetuses of twin gestations between November 2006 and June 2016. Fetuses with major congenital anomalies or chromosomal abnormalities were excluded. Estimated fetal weight was calculated using the Hadlock 1985 formula. Linear mixed models were used to allow for multiple but inconsistent observations among individuals, and to account for intertwin differences as well as for gender...
January 10, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28004484/adolescent-life-with-diabetes-gender-matters-for-level-of-distress-experiences-from-the-national-tods-study
#8
Gun Forsander, Mette Bøgelund, Josephine Haas, Ulf Samuelsson
OBJECTIVE: To examine the relationship between diabetes distress and gender, and the association with glycemic control, social support, health behaviors, and socio-economic status. METHODS: All adolescents, aged 15 to 18 years, in the national, pediatric diabetes registry SWEDIABKIDS with type 1 diabetes were invited to complete an online questionnaire. A total of 2112 teenagers were identified. RESULTS: 453 complete responses were valid for analyses...
December 22, 2016: Pediatric Diabetes
https://www.readbyqxmd.com/read/27979222/effects-of-sulfur-dioxide-concentration-on-organic-acids-and-%C3%AE-carotene-in-dried-apricots-during-storage
#9
Ayşenur Salur-Can, Meltem Türkyılmaz, Mehmet Özkan
The effects of various sulfur dioxide (SO2) concentrations (0, 451, 832, 1594, 2112 and 3241mg/kg) on the profiles and contents of organic acids (OAs) and β-carotene in sulfured dried apricots (SDAs) were investigated during storage at 4, 20 and 30°C for 379days. In all samples, four OAs [malic acid (MA), citric acid (CA), succinic acid (SA) and oxalic acid (OXA)] were identified. SA (13.9-31.8g/kgdw) was the major OA in SDAs containing SO2 at lower than 1594mgSO2/kg, while MA (11.7-11.7g/kgdw) was the major OA in SDAs containing SO2 at higher than 1594mgSO2/kg...
April 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27959508/transformation-of-the-non-selective-aminocyclohexanol-based-hsp90-inhibitor-into-a-grp94-seletive-scaffold
#10
Sanket J Mishra, Suman Ghosh, Andrew R Stothert, Chad A Dickey, Brian S J Blagg
Glucose regulated protein 94 kDa, Grp94, is the endoplasmic reticulum (ER) localized isoform of heat shock protein 90 (Hsp90) that is responsible for the trafficking and maturation of toll-like receptors, immunoglobulins, and integrins. As a result, Grp94 has emerged as a therapeutic target to disrupt cellular communication, adhesion, and tumor proliferation, potentially with fewer side effects compared to pan-inhibitors of all Hsp90 isoforms. Although, the N-terminal ATP binding site is highly conserved among all four Hsp90 isoforms, recent cocrystal structures of Grp94 have revealed subtle differences between Grp94 and other Hsp90 isoforms that has been exploited for the development of Grp94-selective inhibitors...
December 13, 2016: ACS Chemical Biology
https://www.readbyqxmd.com/read/27884041/follow-up-strategies-for-patients-treated-for-non-metastatic-colorectal-cancer
#11
REVIEW
Mark Jeffery, Brigid E Hickey, Phil N Hider, Adrienne M See
BACKGROUND: It is common clinical practice to follow patients with colorectal cancer (CRC) for several years following their curative surgery or adjuvant therapy, or both. Despite this widespread practice, there is considerable controversy about how often patients should be seen, what tests should be performed, and whether these varying strategies have any significant impact on patient outcomes. This is the second update of a Cochrane Review first published in 2002 and first updated in 2007...
November 24, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27794394/who-should-be-checked-for-hepatitis-c-virus-infection-in-endemic-areas
#12
Wattana Sukeepaisalncharoen, Udomlack Peansukwech, Kittisak Sawanyawisuth
OBJECTIVE: To find additional factors suggestive of hepatitis C virus (HCV) infection in the general population by using data from a hepatitis virus survey. METHODS: This study collected data of HCV infection from a hepatitis virus survey. The survey was conducted in 13 provinces in the northeast Thailand in 2014 and 2015. During the survey, a blood test was performed to screen for HCV. A questionnaire was also distributed to all participants asking about baseline characteristics, risk factors for HCV infection, and daily life activities...
October 2016: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/27774806/-retired-physicians-in-hungary-nationwide-representative-study
#13
Zsuzsa Győrffy, Zsuzsanna Szél, Edmond Girasek
INTRODUCTION: The aging population and the aging physician society is an important challenge of the New Millenium. Despite this, very few publications are dealing with the older generations' physical and mental well-being, quality of life and working conditions. AIM: The aim of this study was to describe the retired physicians populations' (n = 2112) demographic data, work status, income and health status. METHOD: Data of this representative, cross-sectional epidemiological study was obtained from online and paper-based questionnaires completed by 2112 retired physicians...
October 2016: Orvosi Hetilap
https://www.readbyqxmd.com/read/27745903/clinical-characteristics-and-outcomes-of-diffuse-alveolar-hemorrhage-in-patients-with-systemic-lupus-erythematosus
#14
Dam Kim, Jeongim Choi, Soo-Kyung Cho, Chan-Bum Choi, Tae-Hwan Kim, Jae-Bum Jun, Dae-Hyun Yoo, Sang-Cheol Bae, Yoon-Kyoung Sung
OBJECTIVE: To identify the clinical characteristics of diffuse alveolar hemorrhage (DAH) compared to other types of acute diffuse lung infiltration in SLE patients, and the factors associated with mortality in these patients. METHODS: We studied a retrospective cohort including SLE patients with acute diffuse lung infiltration on thoracic CT between January 2004 and August 2014. We divided them into 2 groups, a DAH and a non-DAH group, and compared the clinical characteristics and outcomes in the 2 groups...
September 14, 2016: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/27687753/telehealth-monitor-to-measure-physical-activity-and-pressure-relief-maneuver-performance-in-wheelchair-users
#15
Ariel V Dowling, Valerie Eberly, Somboon Maneekobkunwong, Sara J Mulroy, Philip S Requejo, Joseph T Gwin
The purpose of this study was to demonstrate the feasibility of a device for monitoring pressure relief maneuvers and physical activity for wheelchair users. The device counts the number of wheel-pushes based on wheelchair acceleration and measures pressure relief maneuvers using a seat-sensor consisting of three force sensing resistors. To establish the feasibility of the seat-sensor for the detection of pressure relief maneuvers, ten wheelchair users and ten non-disabled controls completed a series of wheelchair depression raises, forward trunk leans, and lateral trunk leans...
September 29, 2016: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/27533472/acute-adverse-reactions-to-nonionic-iodinated-contrast-media-for-ct-prospective-randomized-evaluation-of-the-effects-of-dehydration-oral-rehydration-and-patient-risk-factors
#16
RANDOMIZED CONTROLLED TRIAL
Utaroh Motosugi, Tomoaki Ichikawa, Katsuhiro Sano, Hiroshi Onishi
OBJECTIVE: The objective of our study was to determine the effects of dehydration and oral rehydration on the incidence of acute adverse reactions to iodinated contrast media administered during abdominal and pelvic CT in outpatients. SUBJECTS AND METHODS: For our prospective randomized study performed at a single institution, adult outpatients undergoing contrast-enhanced abdominal CT were randomly divided into a rehydration group (n = 2244 patients [1379 men and 865 women]; mean age, 65...
November 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27420968/effect-of-snx-2112-on-proliferation-of-esophageal-cancer-cells-via-regulation-of-excision-repair-cross-complementing-1-epidermal-growth-factor-receptor-and-p53-expression
#17
C Y Li, Y J Ren, Y D Li
SNX-2112 is a potential molecular targeted therapeutic drug against esophageal cancer (EC). However, its exact mechanism of action remains to be explained. The aim of this study was to investigate the effect of SNX-2112 on excision repair cross- complementing 1 (ERCC1), epidermal growth factor receptor (EGFR), and p53, to elucidate the mechanism of action of SNX-2112 on EC. Fresh tumor sections were surgically obtained from 65 patients with EC, and the expression of ERCC1, EGFR, and p53 was determined by immunohistochemical staining...
June 24, 2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27360937/an-intervention-to-reduce-sedentary-time-and-change-perceived-wellness-in-women-office-workers-2112-board-264-june-2-3-30-pm-5-00-pm
#18
Joyan Urda, Jeffrey Lynn, Beth Larouere
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27306113/manipulating-the-charge-state-of-au-clusters-on-rutile-tio2-110-single-crystal-surfaces-through-molecular-reactions-probed-by-infrared-spectroscopy
#19
Yunjun Cao, Shujun Hu, Min Yu, Tingting Wang, Shiming Huang, Shishen Yan, Mingchun Xu
The charge state of Au clusters deposited on rutile TiO2(110) single crystal surfaces was studied by UHV-FTIRS using CO as a probe. The as-deposited Au clusters on oxidized TiO2(110) surfaces are electrically neutral and are identified by the 2105-2112 cm(-1) vibrational frequency of adsorbed CO depending on Au coverage. Annealing Au/TiO2(110) in a moderate O2 atmosphere at 400 K blue shifts the CO vibrational frequency by only 2-3 cm(-1) both on bare TiO2(110) surfaces and on Au clusters. However, NO exposure blue shifts the CO vibrational frequency by 16-26 cm(-1) for CO adsorbed on Au atoms near the interface and by 3-4 cm(-1) for CO adsorbed on top of Au clusters...
July 14, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27231263/chitosan-functionalised-single-walled-carbon-nanotube-mediated-drug-delivery-of-snx-2112-in-cancer-cells
#20
Lixia Zheng, Shao Wu, Li Tan, Huo Tan, Baodan Yu
Delivery of amphiphobic drugs (insoluble in both water and oil) has been a great challenge in drug delivery. SNX-2112, a novel inhibitor of Hsp90, is a promising drug candidate for treating various types of cancers; however, the insolubility greatly limits its clinical application. This study aimed to build a new type of drug delivery system using single-walled carbon nanotubes (SWNTs) for controllable release of SNX-2112; chitosan (CHI) was non-covalently added to SWNTs to improve their biocompatibility. SWNTs-CHI demonstrated high drug-loading capability; the release of SNX-2112 was pH triggered and time related...
September 2016: Journal of Biomaterials Applications
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