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spinal cord infarction

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https://www.readbyqxmd.com/read/28740568/methane-suppresses-microglial-activation-related-to-oxidative-inflammatory-and-apoptotic-injury-during-spinal-cord-injury-in-rats
#1
WeiHeng Wang, Xiaodong Huang, Jian Li, Aijun Sun, Jiangming Yu, Ning Xie, YanHai Xi, Xiaojian Ye
OBJECTIVE: We investigated the hypothesis that methane-rich saline (MS) can be used to repair spinal cord injury (SCI) in a rat model through suppressing microglial activation related to oxidative, inflammatory, and apoptotic injury. METHODS: MS was injected intraperitoneally in rats after SCI. Hematoxylin-eosin (HE) staining, oxidative stress, inflammatory parameters, and cell apoptosis were detected 72 h after SCI to determine the optimal dose. Then, we investigated the protective mechanisms and the long-term effects of MS on SCI...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28718588/-spinal-injection-risks-and-side-effects
#2
Evangelia Passia, Stéphane Genevay
The efficacy of spinal injection for chronic spinal pain is dubious for most conditions. They are however frequently prescribed. Side effects are poorly reported in the literature. In addition to benign and transient problems, serious and lethal side effects have been reported due to infection, hematoma or central and spinal cord infarctions which could be related to intravascular injection of corticoids. Although their frequency is excessively low, they should be discussed with every patient before prescription and should be mentioned in the consent form...
March 8, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28717781/spinal-cord-infarction-mimicking-ischemic-heart-disease
#3
Dae Won Lee, Yoon Hee Choi
Spinal cord infarction is a rare condition and is easily misdiagnosed owing to its initial non-specific manifestation. We report a case of a 77-year-old man who presented with chest pain and upper back pain initially, and was misdiagnosed with a myocardial infarction. Four hours after admission, he complained of numbness in his entire left leg below the knee, with rapid deterioration of neurological symptoms. After 9 hours, loss of sensation progressed up to the T4 dermatome, strength of both lower extremities deteriorated to grade 0, and decrease in anal tone and deep tendon reflex was observed...
June 2017: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/28702119/a-population-based-study-of-the-incidence-of-acute-spinal-cord-infarction
#4
Adnan I Qureshi, Mohammad Rauf Afzal, M Fareed K Suri
BACKGROUND: There is a paucity of reliable data regarding incidence of acute spinal cord infarction in population-based studies. OBJECTIVES: To determine the incidence of acute spinal cord infarction using a population-based design. METHODS: Medical records and neuroimaging data of all patients with acute spinal cord infarction from Stearns and Benton Counties, Minnesota, between January 1, 2010 and May 31, 2014 were reviewed. Patients with a first-time diagnosis of spinal cord infarction were categorized as primary or secondary depending upon underlying etiology identified...
June 2017: Journal of Vascular and Interventional Neurology
https://www.readbyqxmd.com/read/28690873/spinal-cord-infarction-in-a-sick-neonate-from-predominant-haemorrhagic-aetiology-a-case-report
#5
Richa Kulshrestha, Joy R Chowdhury, Radhesh K Lalam, Nigel T Kiely
INTRODUCTION: Spinal cord injuries in new born infants following a traumatic delivery or umbilical cord catheterisation due to thromboembolism are well known. Cases with atraumatic acute onset of neonatal paraplegia have also been described in preterm babies or babies born small for gestational age with a stormy postnatal course related to ischaemic aetiology. We describe a rare case of infarction of the spinal cord from a predominant haemorrhagic aetiology. CASE PRESENTATION: A term female baby, first child of unrelated parents, was born by normal vaginal delivery...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28688063/spinal-cord-infarcts-risk-factors-management-and-prognosis
#6
REVIEW
Deena M Nasr, Alejandro Rabinstein
There are no standard guidelines for treatment of spinal cord ischemia due to how rare it is and the diverse etiology and presentations involved. In addition, to date, there have been no large clinical trials examining ideal pharmacologic treatment options for spinal cord infarct. In our practice, we rely on hemodynamic augmentation initiated as soon as possible. Otherwise, treatment is usually geared towards the etiology of spinal cord ischemia. For instance, spinal cord ischemia occurring after aortic aneurysmal repair may improve with CSF drainage through a lumbar catheter in the periprocedural setting...
August 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/28667382/magnetic-resonance-imaging-and-clinical-features-in-acute-and-subacute-myelopathies
#7
REVIEW
Stefan Weidauer, Marlies Wagner, Michael Nichtweiß
Differential diagnosis of acute and subacute transverse myelopathy includes inflammatory, infectious, vascular, metabolic and paraneoplastic etiologies. Information on the diagnostic approach to transverse myelopathy with regard to daily clinical practice is provided. The differentiation between five lesion patterns on magnetic resonance imaging (MRI) in myelitis may be helpful: (1) longitudinal extensive transverse myelitis, (2) short segment ovoid or peripherally located, (3) "polio-like", (4) granulomatous and (5) segmental with rash...
June 30, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/28655811/rates-of-spinal-cord-infarction-after-repair-of-aortic-aneurysm-or-dissection
#8
Gino Gialdini, Neal S Parikh, Abhinaba Chatterjee, Michael P Lerario, Hooman Kamel, Darren B Schneider, Babak B Navi, Santosh B Murthy, Costantino Iadecola, Alexander E Merkler
BACKGROUND AND PURPOSE: The rate of spinal cord infarction (SCI) after surgical or endovascular repair of an aortic aneurysm or dissection is unclear. METHODS: Using administrative claims data, we identified adult patients discharged from nonfederal acute care hospitals in California, New York, and Florida who underwent surgical or endovascular repair of an aortic aneurysm or dissection between 2005 and 2013. Patients with SCI diagnosed before the aortic repair were excluded...
June 27, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28648010/-experience-of-sun-s-procedure-for-chronic-type-b-dissection-with-aortic-arch-involvement
#9
R D Qi, J M Zhu, L Chen, C N Li, Z Y Qiao, L J Cheng, Y P Ge, H O Hu, Y Xia, X Y Xing, T Zheng, Y M Liu, L Z Sun
Objective: To study the surgical treatment of chronic type B dissection with aortic arch involvement using Sun's procedure. Methods: Between February 2009 and December 2015, 29 patients [20 males, 9 females, with a mean age of (41±12) years, range 24-64 years] with type B dissection with aortic arch involvement underwent Sun's procedure. Sixteen patient had a history of hypertension. Marfan syndrome was observed in 9 cases, coronary artery disease in 3 cases, mitral regurgitation in 3 patients, cerebrovascular disease in one patient...
June 27, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28605426/biomarkers-of-cerebral-injury-and-inflammation-in-pediatric-tuberculous-meningitis
#10
Ursula K Rohlwink, Katya Mauff, Katalin A Wilkinson, Nico Enslin, Emmanuel Wegoye, Robert J Wilkinson, Anthony A Figaji
Background: Tuberculous meningitis (TBM) leads to death or disability in half the affected individuals. Tools to assess severity and predict outcome are lacking. Neuro-specific biomarkers could serve as markers of the severity and evolution of brain injury, but have not been widely explored in TBM. We examined biomarkers of neurological injury (neuromarkers) and inflammation in pediatric TBM and their association with outcome. Methods: Blood and cerebrospinal fluid (CSF) of children with TBM and hydrocephalus taken on admission and over 3 weeks were analysed for neuromarkers S100B, neuron-specific enolase (NSE) and glial fibrillary acidic protein (GFAP), and multiple inflammatory markers...
June 9, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28596039/assessment-of-aortic-wall-thrombus-predicts-outcomes-of-endovascular-repair-of-complex-aortic-aneurysms-using-fenestrated-and-branched-endografts
#11
Mauricio Ribeiro, Gustavo S Oderich, Thanila Macedo, Terri J Vrtiska, Jan Hofer, Julia Chini, Bernardo Mendes, Stephen Cha
OBJECTIVE: The goal of this study was to investigate the correlation between atherothrombotic aortic wall thrombus (AWT) and clinical outcomes in patients treated by fenestrated-branched endovascular aortic repair (F-BEVAR) and present a new classification system for assessment of AWT burden. METHODS: The clinical data of 301 patients treated for pararenal and thoracoabdominal aortic aneurysms (TAAAs) by F-BEVAR was reviewed. The study excluded 89 patients with extent I to III TAAA because of extensive laminated thrombus within the aneurysm sac...
June 5, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28578817/childhood-idiopathic-spinal-cord-infarction-description-of-7-cases-and-review-of-the-literature
#12
Claire Bar, Emmanuel Cheuret, Pierre Bessou, Jean-Michel Pedespan
OBJECTIVES: To describe the clinical course, neuroimaging findings and functional outcome of idiopathic spinal cord infarction (SCI) in adolescents. METHODS: Retrospective and descriptive analyses of seven patients with idiopathic SCI and 50 additional cases from the literature were included. Data collected concerned clinical presentation, MRI findings, initial diagnosis, treatments and functional outcome at the last medical visit. RESULTS: Mean age at presentation was 13...
May 31, 2017: Brain & Development
https://www.readbyqxmd.com/read/28548204/endovascular-treatment-for-ruptured-abdominal-aortic-aneurysm
#13
REVIEW
Stephen Badger, Rachel Forster, Paul H Blair, Peter Ellis, Frank Kee, Denis W Harkin
BACKGROUND: An abdominal aortic aneurysm (AAA) (pathological enlargement of the aorta) is a condition that can occur as a person ages. It is most commonly seen in men older than 65 years of age. Progressive aneurysm enlargement can lead to rupture and massive internal bleeding, which is fatal unless timely repair can be achieved. Despite improvements in perioperative care, mortality remains high (approximately 50%) after conventional open surgical repair. Endovascular aneurysm repair (EVAR), a minimally invasive technique, has been shown to reduce early morbidity and mortality as compared to conventional open surgery for planned AAA repair...
May 26, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28546875/spinal-cord-infarct-caused-from-suspected-fibrocartilaginous-embolism
#14
Ayham M Alkhachroum, Danielle Weiss, Alan Lerner, Michael A De Georgia
INTRODUCTION: We report a case of spinal cord infarct as a result of suspected fibrocartilaginous embolism (FCE). CASE PRESENTATION: A 23-year-old man presented with sudden onset cervical and upper back pain followed by progressive weakness in his extremities after throwing a baseball. History, neurologic examination and spinal cord imaging were consistent with spinal cord infarct. We believe the cause was from FCE. DISCUSSION: Though rare, physicians should be familiar with this diagnosis and the proposed mechanisms...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28460036/reoperative-repair-of-descending-thoracic-and-thoracoabdominal-aneurysms%C3%A2
#15
Christopher Lau, Mario Gaudino, Ivancarmine Gambardella, Erin Mills, Monica Munjal, Mohamed Elsayed, Leonard Girardi
OBJECTIVES: To evaluate the results of reoperation on descending thoracic and thoracoabdominal aneurysms. METHODS: Sixty-nine consecutive patients undergoing reoperative aneurysm repair (20 descending thoracic and 49 thoracoabdominal) were compared to 602 contemporary primary repairs. Propensity matching was used to reduce observable differences in preoperative characteristics. RESULTS: The reoperation group was younger (60.2 vs 65.3 years, P  = 0...
April 27, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28446898/delayed-hospital-presentation-and-neuroimaging-in-non-surgical-spinal-cord-infarction
#16
Slaven Pikija, Johannes Sebastian Mutzenbach, Alexander B Kunz, Raffaele Nardone, Stefan Leis, Ildiko Deak, Mark R McCoy, Eugen Trinka, Johann Sellner
BACKGROUND: Lack of timely recognition and neuroimaging may be a barrier to reperfusion efforts in acute spinal cord infarction. METHODS: We performed a retrospective study of patients diagnosed with acute non-surgical spinal cord infarction at our tertiary academic center from 2001 to 2015. We studied parameters associated with time from symptom onset to initial hospital presentation and magnetic resonance imaging (MRI) of the spinal cord. RESULTS: We identified 39 patients among whom anterior spinal artery syndrome was the most frequent presentation (87...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28431007/letter-surfer-s-myelopathy-a-rare-form-of-spinal-cord-infarction-in-novice-surfers-a-systematic-review
#17
John R Silver
No abstract text is available yet for this article.
April 20, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28409289/expert-s-comment-concerning-grand-rounds-case-entitled-acute-complete-paraplegia-of-a-8-year-old-girl-caused-by-spinal-cord-infarction-following-minor-trauma-complicated-with-longitudinal-signal-change-of-spinal-cord-by-k-nagata-et-al-eur-spine-j-2017-doi-10
#18
https://www.readbyqxmd.com/read/28404376/watershed-spinal-cord-infarction-developing-after-a-hypotensive-episode-secondary-to-massive-rectus-sheath-hematoma
#19
Adviye Ergun, Oktay Akalın, Mehmet Sukru Sahin, Kosdere Serkan
No abstract text is available yet for this article.
July 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28402553/in-reply-surfer-s-myelopathy-a-rare-form-of-spinal-cord-infarction-in-novice-surfers-a-systematic-review
#20
Brett A Freedman, David G Malone, Peter A Rasmussen, Edward C Benzel
No abstract text is available yet for this article.
June 1, 2017: Neurosurgery
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