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Surgical sealant

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https://www.readbyqxmd.com/read/29738754/closure-of-a-post-transplant-bronchial-dehiscence-with-endobronchial-fibrin-sealant
#1
Branden W Luna, Luca Paoletti, Chadrick E Denlinger, Nicholas J Pastis, Timothy P Whelan
Airway complications following lung transplantation are well described and can lead to significant morbidity and mortality. Treatment options for anastomotic dehiscence include expectant management, placement of endobronchial stents, or surgical repair. The use of fibrin sealant instilled via bronchoscopy to seal a dehiscence has not been well described. Our patient is a 57 year old male who underwent orthotropic bilateral lung transplantation for end stage COPD. He was found to have a partial bronchial anastomosis dehiscence and subsequently treated with endobronchial fibrin sealant glue instillation...
May 5, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29730270/management-of-iatrogenic-spinal-cerebrospinal-fluid-leaks-a-cohort-of-124-patients
#2
Royce W Woodroffe, Kirill V Nourski, Logan C Helland, Brian Walsh, Jennifer Noeller, Panagiotis Kerezoudis, Patrick W Hitchon
OBJECTIVES: Cerebrospinal fluid leaks are a frequent complication of spinal surgery, with reported rates between 2 and 20%. Management is highly variable and dependent on comorbidities, complexity of the index procedure, and surgeons' experience. Treatment options include primary or delayed repair, with or without spinal drainage. Using a retrospective cohort, the authors aim to identify the appropriate management of iatrogenic spinal cerebrospinal fluid (CSF) leaks. PATIENTS AND METHODS: We queried our institutional database for postoperative spinal CSF leaks between 1/1/2007 and 3/14/2017 using Current Procedural Terminology (CPT) and International Classification of Disease (ICD) codes...
April 22, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29710057/efficacy-of-dural-sealant-system-for-preventing-brain-shift-and-improving-accuracy-in-deep-brain-stimulation-surgery
#3
Tatsuya Sasaki, Takashi Agari, Ken Kuwahara, Ittetsu Kin, Mihoko Okazaki, Susumu Sasada, Aiko Shinko, Masahiro Kameda, Takao Yasuhara, Isao Date
The success of deep brain stimulation (DBS) depends heavily on surgical accuracy, and brain shift is recognized as a significant factor influencing accuracy. We investigated the factors associated with surgical accuracy and showed the effectiveness of a dural sealant system for preventing brain shift in 32 consecutive cases receiving DBS. Thirty-two patients receiving DBS between March 2014 and May 2015 were included in this study. We employed conventional burr hole techniques for the first 18 cases (Group I) and a dural sealant system (DuraSeal) for the subsequent 14 cases (Group II)...
May 1, 2018: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/29704585/the-role-of-human-acellular-dermis-in-preventing-fistulas-after-bladder-neck-transection-in-the-exstrophy-epispadias-complex
#4
Karl S Benz, John Jayman, Mahir Maruf, Gregory Joice, Matthew Kasprenski, Nikolai Sopko, Heather Di Carlo, John Gearhart
OBJECTIVES: To evaluate Human Acellular Dermis (HAD) as an adjunct during Bladder Neck Transection (BNT) by comparing surgical outcomes with other types of tissue interposition. METHODS: A prospectively-maintained institutional database of Exstrophy-Epispadias Complex (EEC) patients was reviewed for those who underwent a BNT with at least 6 months follow-up. The primary outcome was the occurrence of BNT-related fistulas. RESULTS: In total, 147 EEC patients underwent a BNT with a mean follow-up time of 6...
April 25, 2018: Urology
https://www.readbyqxmd.com/read/29696515/use-of-bioglue%C3%A2-to-seal-a-difficult-to-treat-air-leak-in-a-complicated-empyema-patient
#5
Vasileios Kouritas, Emmanouel Kefaloyannis, Peter Tcherveniakov
Surgical sealants have been used in thoracic surgery in an effort to reduce air leak duration, intercostal drain duration, length of stay and complications. They are instilled over a defect usually treated with other means. We herein present the technique of controlling a difficult to treat defect by directly instilling Bioglue™ alone into a crater, caused during empyema Video-assisted thoracic surgery in a 50-year-old patient with a trapped lung. This deep crater had caused a significant air leak rendering intraoperative ventilation challenging...
April 25, 2018: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29682257/therapeutic-efficiency-of-platelet-gel-for-the-treatment-of-oral-ulcers-related-to-chronic-graft-versus-host-disease-after-allogeneic-haematopoietic-stem-cell-transplantation
#6
A Picardi, A S Ferraro, M Miranda, F Meconi, A Lanti, G Adorno, W Arcese, P Bollero
Background: Platelet (PLT) gel has been successfully used in tissue regeneration of diabetic and surgical wounds through the releasing of growth factors such as basic fibroblast and PLT-derived growth factors. Based on this background, our previous clinical trial have assessed the feasibility and efficacy of PLT gel for the treatment of muco-cutaneous lesions related to graft versus host disease (GvHD) after allogeneic haematopoietic stem cell transplantion (HSCT). The promising results reported in a small series of 6 patients, of whom 1 with oral ulcers, represent the rationale of the present study...
October 2017: Oral & Implantology
https://www.readbyqxmd.com/read/29681965/the-use-of-an-autologous-fibrin-sealant-during-a-complex-cardiac-surgical-procedure
#7
Radosław Jarząbek, Paweł Bugajski, Krzysztof Greberski, Ryszard Kalawski
No abstract text is available yet for this article.
March 2018: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/29681920/combination-of-heterologous-fibrin-sealant-and-bioengineered-human-embryonic-stem-cells-to-improve-regeneration-following-autogenous-sciatic-nerve-grafting-repair
#8
Roghayeh Mozafari, Sergiy Kyrylenko, Mateus Vidigal Castro, Rui Seabra Ferreira, Benedito Barraviera, Alexandre Leite Rodrigues Oliveira
Background: Peripheral nerve injury is a worldwide clinical problem, and the preferred surgical method for treating it is the end-to-end neurorrhaphy. When it is not possible due to a large nerve gap, autologous nerve grafting is used. However, these surgical techniques result in nerve regeneration at highly variable degrees. It is thus very important to seek complementary techniques to improve motor and sensory recovery. One promising approach could be cell therapy. Transplantation therapy with human embryonic stem cells (hESCs) is appealing because these cells are pluripotent and can differentiate into specialized cell types and have self-renewal ability...
2018: Journal of Venomous Animals and Toxins Including Tropical Diseases
https://www.readbyqxmd.com/read/29658322/clinical-effectiveness-and-versatility-of-a-sealing-hemostatic-patch-hemopatch-in-multiple-surgical-specialties
#9
Kevin M Lewis, Shelly Ikeme, Tolu Olubunmi, Carl Erik Kuntze
Intraoperative surgical sealants and hemostatic agents have been shown to reduce postoperative complications, transfusions and hospital resource utilization. Despite availability of these agents, the incidence and burden of bleeding remains high and surgeons' requirements for hemostatic control continue to evolve. A burgeoning class of hemostatic agents are hemostatic patches, which offer package-to-patient readiness and direct application. In addition, hemostatic patches may provide tissue sealing capabilities...
April 16, 2018: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/29557532/cisterna-magna-arachnoid-membrane-suturing-decreases-incidence-of-pseudomeningocele-formation-and-incisional-csf-leakage
#10
David Pitskhelauri, Elina Kudieva, Dmitrii Moshchev, Evgeny Ananev, Michail Shifrin, Gleb Danilov, Tatiana Melnikova-Pitskhelauri, Igor Kachkov, Andrey Bykanov, Alexander Sanikidze
OBJECTIVE: A pseudomeningocele and an incisional cerebrospinal fluid leak are considered frequent complications following neurosurgical operations. The rate of these complications especially increases following neurosurgical procedures on the posterior cranial fossae. According to some publications, the rate of pseudomeningoceles has been reported as high as 40%, whereas that of incisional cerebrospinal fluid leaks is up to 17%. For the purposes of reducing the risk of these complications after a midline suboccipital craniotomy, we propose suturing the arachnoid membrane of the cisterna magna...
May 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29524461/endolymphatic-interventions-for-the-treatment-of-chylothorax-and-chylous-ascites-in-neonates-technical-and-clinical-success-and-complications
#11
Rajiv N Srinivasa, Jeffrey Forris Beecham Chick, Joseph J Gemmete, Anthony N Hage, Ravi N Srinivasa
BACKGROUND: The aim of this study was to report the technical and clinical success of performing minimally invasive endolymphatic embolization in neonates presenting with a chylothorax or chylous ascites. METHODS: Three neonates, 2 males and 1 female, with a mean age of 28 days (range: 19-39 days) presented with a chylothorax or chylous ascites that was refractory to conservative management. All 3 patients (1 previously reported) underwent intranodal lymphangiography, followed by thoracic duct embolization, with 1 patient undergoing additional sclerosis of the retroperitoneal abdominal lymphatics...
March 7, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29512618/the-hemostatic-power-of-fat-an-effective-inexpensive-and-biocompatible-method-to-achieve-hemostasis-in-cardiac-surgery
#12
María Elena Arnáiz-García, Jose María González-Santos, Javier López-Rodríguez, Ana María Arnáiz-García, Javier Arnáiz
Postoperative bleeding with its important socioeconomic cost is associated with an increased morbidity and mortality. It causes hemodynamic instability, increases blood loss, and multiplies the number of transfusions required. Especially in vascular or aortic surgery, postoperative bleeding can become a life-threatening complication due to anticoagulant or antiaggregation preoperative status or postoperative coagulation dysfunction after a high level of heparinization. Presently described is the case of a patient who underwent an aortic valve and ascending aorta replacement...
March 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/29465600/a-novel-endobronchial-approach-to-massive-hemoptysis-complicating-silicone-y-stent-placement-for-tracheobronchomalacia-a-case-report
#13
Changwan Ryu, Daniel Boffa, Kyle Bramley, Margaret Pisani, Jonathan Puchalski
RATIONALE: Airway stabilization for severe, symptomatic tracheobronchomalacia (TBM) may be accomplished by silicone Y-stent placement. Common complications of the Y-stent include mucus plugging and granulation tissue formation. PATIENT CONCERNS: We describe a rare case of massive hemoptysis originating from a silicone Y-stent placed for TBM. DIAGNOSES: An emergent bronchoscopy showed an actively bleeding, pulsatile vessel at the distal end of the left bronchial limb of the Y-stent...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29462710/fibrin-glue-mesh-fixation-combined-with-mesenchymal-stem-cells-or-exosomes-modulates-the-inflammatory-reaction-in-a-murine-model-of-incisional-hernia
#14
Rebeca Blázquez, Francisco Miguel Sánchez-Margallo, Verónica Álvarez, Alejandra Usón, Federica Marinaro, Javier G Casado
Surgical meshes are effective and frequently used to reinforce soft tissues. Fibrin glue (FG) has been widely used for mesh fixation and is also considered an optimal vehicle for stem cell delivery. The aim of this preclinical study was to evaluate the therapeutic effect of MSCs and their exosomes combined with FG for the treatment of incisional hernia. A murine incisional hernia model was used to implant surgical meshes and different treatments with FG, MSCs and exo-MSCs were applied. The implanted meshes were evaluated at day 7 by anatomopathology, cellular analysis of infiltrating leukocytes and gene expression analysis of TH1/TH2 cytokines, MMPs, TIMPs and collagens...
April 15, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29462440/metro-a-new-surgical-sealant
#15
David L Penn, John H Chi
No abstract text is available yet for this article.
March 1, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29427781/retroperitoneal-laparoscopic-para-aortic-lymphadenectomy-in-para-aortic-staging-of-locally-advanced-cervical-cancer
#16
Daniel Vázquez-Vicente, Bárbara Fernández Del Bas, José García Villayzán, Javier Plaza Arranz, Luis Chiva
STUDY OBJECTIVE: To review/learn a surgical technique not very well-known by gynecologic oncologists. DESIGN: Level of evidence III. SETTING: A review of a surgical technique with emphasis on the para-aortic sentinel lymph nodes using indocyanine green. INTERVENTION: The film features the following steps to perform the procedure: 1. Creating a retroperitoneal window. 2. What to do if the peritoneum is torn. 3. Finding the psoas muscle, right ureter, and common iliac artery...
February 7, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29406579/intraoperative-interventions-for-preventing-surgical-site-infection-an-overview-of-cochrane-reviews
#17
REVIEW
Zhenmi Liu, Jo C Dumville, Gill Norman, Maggie J Westby, Jane Blazeby, Emma McFarlane, Nicky J Welton, Louise O'Connor, Julie Cawthorne, Ryan P George, Emma J Crosbie, Amber D Rithalia, Hung-Yuan Cheng
BACKGROUND: Surgical site infection (SSI) rates vary from 1% to 5% in the month following surgery. Due to the large number of surgical procedures conducted annually, the costs of these SSIs can be considerable in financial and social terms. Many interventions are used with the aim of reducing the risk of SSI in people undergoing surgery. These interventions can be broadly delivered at three stages: preoperatively, intraoperatively and postoperatively. The intraoperative interventions are largely focused on decontamination of skin using soap and antiseptics; the use of barriers to prevent movement of micro-organisms into incisions; and optimising the patient's own bodily functions to promote best recovery...
February 6, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29359610/effectiveness-of-a-bipolar-vessel-sealant-device-for-ovariohysterectomy-in-cats-with-pyometra
#18
Jean-François Boursier, Jean Bassanino, Dimitri Leperlier
Objectives The objective was to describe the use of a bipolar vessel sealant device for complete ovariohysterectomy in cats - both the ovarian pedicle and the uterine body and vessels - and to report on the feasibility of ovariohysterectomy in cats with pyometra. Methods Cats with confirmed pyometra and whose owners agreed to the surgical procedure were prospectively included in the study. Ovaries were visualised and the vessel sealant device was used to coagulate and cut the suspensory ligament, the ovarian pedicle and the broad ligament up to the level of the uterine body...
January 1, 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29280707/successful-conservative-treatment-of-enterocutaneous-fistula-with-cyanoacrylate-surgical-sealant-case-report
#19
N Musa, F Aquilino, P Panzera, G Martines
AIM: Enterocutaneous (EC) fistula is an abnormal communication between the gastrointestinal tract and the skin. The majority of EC fistulas result from surgery. Only 15-25% of EC fistulas are spontaneous and they often result from underlying diseases such as Crohn's disease, radiation and chemotherapy. CASE REPORT: A 62-year old woman who, in 2012, underwent Pylorus-preserving cephalic pancreaticoduodenectomy (PPPD sec. Traverso-Longmire), due to an advanced pancreatic ductal adenocarcinoma (pT3N1M1)...
September 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/29224839/intraoperative-costs-of-video-assisted-thoracoscopic-lobectomy-can-be-dramatically-reduced-without-compromising-outcomes
#20
Michael T Richardson, Leah M Backhus, Mark F Berry, Daniel G Vail, Kelsey C Ayers, Jalen A Benson, Prasha Bhandari, Mehran Teymourtash, Joseph B Shrager
OBJECTIVE: To determine whether surgeon selection of instrumentation and other supplies during video-assisted thoracoscopic lobectomy (VATSL) can safely reduce intraoperative costs. METHODS: In this retrospective, cost-focused review of all video-assisted thoracoscopic surgery anatomic lung resections performed by 2 surgeons at a single institution between 2010 and 2014, we compared VATSL hospital costs and perioperative outcomes between the surgeons, as well as costs of VATSL compared with thoracotomy lobectomy (THORL)...
March 2018: Journal of Thoracic and Cardiovascular Surgery
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