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https://www.readbyqxmd.com/read/28329332/excessive-daytime-sleepiness-predicts-neurodegeneration-in-idiopathic-rem-sleep-behavior-disorder
#1
Junying Zhou, Jihui Zhang, Siu Ping Lam, Joey Wy Chan, Vincent Mok, Anne Chan, Shirley Xin Li, Yaping Liu, Xiangdong Tang, Wing Ho Yung, Yun Kwok Wing
Study Objectives: To determine the association of excessive daytime sleepiness (EDS) with the conversion of neurodegenerative diseases in patients with idiopathic REM sleep behavior disorder (iRBD). Methods: A total of 179 patients with iRBD (79.1% males, mean age = 66.3 ± 9.8 years) were consecutively recruited. Forty-five patients with Epworth Sleepiness Scale score ≥ 14 were defined as having EDS. Demographic, clinical and polysomnographic data were compared between iRBD patients with and without EDS...
March 16, 2017: Sleep
https://www.readbyqxmd.com/read/28329254/periodic-limb-movements-and-white-matter-hyperintensities-in-first-ever-minor-stroke-or-high-risk-tia
#2
Mark I Boulos, Brian J Murray, Ryan T Muir, Fuqiang Gao, Gregory M Szilagyi, Menal Huroy, Alexander Kiss, Arthur S Walters, Sandra E Black, Andrew S Lim, Richard H Swartz
Study Objectives: Emerging evidence suggests that periodic limb movements (PLMs) may contribute to the development of cerebrovascular disease. White matter hyperintensities (WMHs), a widely accepted biomarker for cerebral small vessel disease, are associated with incident stroke and death. We evaluated the association between increased PLM indices and WMH burden in patients presenting with stroke or transient ischemic attack (TIA), while controlling for vascular risk factors and stroke severity...
December 29, 2016: Sleep
https://www.readbyqxmd.com/read/28329231/cardiac-protective-effects-of-remote-ischaemic-preconditioning-in-children-undergoing-tetralogy-of-fallot-repair-surgery-a-randomized-controlled-trial
#3
Qingping Wu, Tingting Wang, Shiqiang Chen, Quanjun Zhou, Haobo Li, Na Hu, Yinglu Feng, Nianguo Dong, Shanglong Yao, Zhengyuan Xia
Aims: Remote ischaemic preconditioning (RIPC) by inducing brief ischaemia in distant tissues protects the heart against myocardial ischaemia-reperfusion injury (IRI) in children undergoing open-heart surgery, although its effectiveness in adults with comorbidities is controversial. The effectiveness and mechanism of RIPC with respect to myocardial IRI in children with tetralogy of Fallot (ToF), a severe cyanotic congenital cardiac disease, undergoing open heart surgery are unclear. We hypothesized that RIPC can confer cardioprotection in children undergoing ToF repair surgery...
February 18, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28329227/incident-cardiovascular-events-and-death-in-individuals-with-restless-legs-syndrome-or-periodic-limb-movements-in-sleep-a-systematic-review
#4
Tetyana Kendzerska, Maneesha Kamra, Brian J Murray, Mark I Boulos
Study Objectives: To systematically review the current evidence examining restless legs syndrome (RLS) and periodic limb movements (PLMS) as prognostic factors for all-cause mortality and incident cardiovascular events (CVE) in longitudinal studies published in the adult population. Methods: All English language studies (from 1947 to 2016) found through Medline and Embase, as well as bibliographies of identified articles, were considered eligible. Quality was evaluated using published guidelines...
February 9, 2017: Sleep
https://www.readbyqxmd.com/read/28328865/novel-management-of-distal-tibial-and-fibular-fractures-with-acumed-fibular-nail-and-minimally-invasive-plating-osteosynthesis-technique-a-case-report
#5
Tie-Jun Wang, Wei-Na Ju, Bao-Chang Qi
RATIONALE: Anatomical characteristics, such as subcutaneous position and minimal muscle cover, contribute to the complexity of fractures of the distal third of the tibia and fibula. Severe damage to soft tissue and instability ensure high risk of delayed bone union and wound complications such as nonunion, infection, and necrosis. PATIENT CONCERNS: This case report discusses management in a 54-year-old woman who sustained fractures of the distal third of the left tibia and fibula, with damage to overlying soft tissue (swelling and blisters)...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28328817/retrospective-analysis-of-the-overt-proteinuria-diabetic-kidney-disease-in-the-treatment-of-modified-shenzhuo-formula-for-2-years
#6
Hongdong Chen, Jing Guo, Xuemin Zhao, Xinhui He, Zhongchen He, Linhua Zhao, Xiaolin Tong
The objective of the present study was to evaluate the 2-year effectiveness of modified Shenzhuo formula in the treatment of overt proteinuria diabetic kidney disease (DKD).Patients diagnosed with type 2 DKD in the clinical research database of Prof Xiaolin Tong (>20,000 data points) with >1-year follow-up were screened for this study. Patients' demographic data, chief complaint, present illness, past history, allergic history, personal history, family history, test results, tongue images, pulse information, and prescription information at 1, 1...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28328732/reliable-method-for-avoiding-malrotation-deformity-after-intramedullary-nailing-of-comminuted-femur-fractures-clinical-validation-of-a-previously-described-technique
#7
Ashoke Sathy, Jonathan C Barnwell, Sean N Shahrestani, Daniel Moore
OBJECTIVES: To evaluate a previously described technique using the inherent anteversion of intramedullary nail (IMN) to avoid malrotation in comminuted femur fractures and describe the use of magnetic resonance imaging (MRI) as an alternative method for assessing postoperative femoral version. DESIGN: Prospective consecutive cohort study. SETTING: Level I trauma center. PATIENT/PARTICIPANTS: Twenty-five consecutive patients with comminuted femur fractures (Winquist III/IV, OTA/AO 32-B/32-C) treated by a single surgeon with IMN between September 1, 2011, and February 28, 2015...
April 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28328714/somatic-profile-of-the-elite-boulderers-in-poland
#8
Mariusz Ozimek, Marcin Krawczyk, Emilian Zadarko, Zbigniew Barabasz, Tadeusz Ambroży, Arkadiusz Stanula, Dawid K Mucha, Adam Jurczak, Dariusz Mucha
Ozimek, M, Krawczyk, M, Zadarko, E, Barabasz, Z, Ambroży, T, Stanula, A, Mucha, DK, Jurczak, A, and Mucha, D. Somatic profile of the elite boulderers in Poland. J Strength Cond Res 31(4): 963-970, 2017-The study was designed to determine the values of selected somatic characteristics, body proportions, and the somatotype of elite bouldering climbers in Poland and to establish the relationships between the values of the somatic characteristics and climber's performance in bouldering. The study was conducted in a group of elite sport climbers (n = 10) who were ranked by the Polish Mountaineering Association in 2011, 2012, and 2013...
April 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28328683/surgical-support-during-the-terrorist-attacks-in-paris-13-november-2015-experience-at-b%C3%A3-gin-military-teaching-hospital
#9
Olivier Barbier, Brice Malgras, Camille Choufani, Antoine Bouchard, Didier Ollat, Gilbert Versier
BACKGROUND: Recent conflicts have allowed the French Army Health Service to improve management quality for wartime-injured people during military operations. On 13 November 2015, it was in Paris that France was directly attacked and Bégin Military Teaching Hospital, like several hospitals in Paris, had to face a large number of gunshot victims. Thanks to our operational experience, injured people hospitalized in military hospitals benefited from a management based on triage and damage control (DC) principles...
March 21, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28328660/addressing-the-barriers-to-bioimpedance-spectroscopy-use-in-major-burns-alternate-electrode-placement
#10
Pippa Kenworthy, Tiffany L Grisbrook, Michael Phillips, William Gibson, Fiona M Wood, Dale W Edgar
Bioimpedance spectroscopy (BIS) is a method used to assess body composition and fluid distribution. As a technology for measurement of fluid shifts during acute burn resuscitation, there are potential barriers to its use due to the location of wounds. This study aimed to determine whether alternate electrode positions were a suitable alternative compared to standardized (manufacturer) positions in moderate to large size burns for the measurement of BIS resistance and fluid changes. BIS measurements were collected in standard and alternate electrode placements and in an open wound and Acticoat™ dressing condition...
March 15, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28328304/influence-of-additional-ankle-weights-on-kinematic-variables-of-late-preterm-infants-aged-3-4-months
#11
Jadiane Dionisio, Gabriela Lopes Dos Santos, Eloisa Tudella
The authors analyzed and compared the effect of additional weight on the spatiotemporal parameters of the kicking movement of late preterm and full-term infants. The experiment was divided into 4 conditions: training, baseline, weight, and postweight. In the W condition, a weight of one third the lower limb mass was added to the infant's ankle. During the baseline and postweight conditions, the ankle weight was removed. Late preterm infants do not differ from full-term infants in relation to spatiotemporal variables at 3 and 4 months...
March 22, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/28328141/a-590-kb-deletion-caused-by-non-allelic-homologous-recombination-between-two-line-1-elements-in-a-patient-with-mesomelia-synostosis-syndrome
#12
Tomohiro Kohmoto, Takuya Naruto, Miki Watanabe, Yuji Fujita, Sae Ujiro, Nana Okamoto, Hideaki Horikawa, Kiyoshi Masuda, Issei Imoto
Mesomelia-synostoses syndrome (MSS) is a rare, autosomal-dominant, syndromal osteochondrodysplasia characterized by mesomelic limb shortening, acral synostoses, and multiple congenital malformations due to a non-recurrent deletion at 8q13 that always encompasses two coding-genes, SULF1 and SLCO5A1. To date, five unrelated patients have been reported worldwide, and MMS was previously proposed to not be a genomic disorder associated with deletions recurring from non-allelic homologous recombination (NAHR) in at least two analyzed cases...
April 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28327689/unusual-case-of-failure-to-thrive-type-iii-bartter-syndrome
#13
S Agrawal, K Subedi, P Ray, A Rayamajhi
Bartter syndrome Type III is a rare autosomal recessive disorder resulting from an inherited defect in the thick ascending limb of the loop of henle of the nephrons in kidney. The typical clinical manifestations in childhood are failure to thrive and recurrent episodes of vomiting. Typical laboratory findings which help in the diagnosis are hypokalemic metabolic alkalosis, hypomagnesemia and hypercalciuria. We report a case of Type III Bartter syndrome not responding to repeated conventional treatment of failure to thrive...
September 2016: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28327564/quantification-of-whole-body-and-segmental-skeletal-muscle-mass-using-phase-sensitive-8-electrode-medical-bioelectrical-impedance-devices
#14
A Bosy-Westphal, B Jensen, W Braun, M Pourhassan, D Gallagher, M J Müller
BACKGROUND/OBJECTIVES: Bioelectrical impedance analysis (BIA) provides noninvasive measures of skeletal muscle mass (SMM) and visceral adipose tissue (VAT). This study (i) analyzes the impact of conventional wrist-ankle vs segmental technology and standing vs supine position on BIA equations and (ii) compares BIA validation against magnetic resonance imaging (MRI) and dual X-ray absorptiometry (DXA). SUBJECTS/METHODS: One hundred and thirty-six healthy Caucasian adults (70 men, 66 women; age 40±12 years) were measured by a phase-sensitive multifrequency BIA (seca medical body composition analyzers 515 and 525)...
March 22, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28327549/scaling-and-functional-morphology-in-strigiform-hind-limbs
#15
Meena A Madan, Emily J Rayfield, Jen A Bright
Strigiformes are an order of raptorial birds consisting exclusively of owls: the Tytonidae (barn owls) and the Strigidae (true owls), united by a suite of adaptations aiding a keen predatory lifestyle, including robust hind limb elements modified for grip strength. To assess variation in hind limb morphology, we analysed how the dimensions of the major hind limb elements in subfossil and modern species scaled with body mass. Comparing hind limb element length, midshaft width, and robusticity index (RI: ratio of midshaft width to maximum length) to body mass revealed that femoral and tibiotarsal width scale with isometry, whilst length scales with negative allometry, and close to elastic similarity in the tibiotarsus...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28327505/technical-aspects-and-validation-of-a-new-biofeedback-system-for-measuring-lower-limb-loading-in-the-dynamic-situation
#16
Marco Raaben, Herman R Holtslag, Robin Augustine, Rutger O van Merkerk, Bart F J M Koopman, Taco J Blokhuis
BACKGROUND: A variety of techniques for measuring lower limb loading exists, each with their own limitations. A new ambulatory biofeedback system was developed to overcome these limitations. In this study, we described the technical aspects and validated the accuracy of this system. METHODS: A bench press was used to validate the system in the static situation. Ten healthy volunteers were measured by the new biofeedback system and a dual-belt instrumented treadmill to validate the system in the dynamic situation...
March 22, 2017: Sensors
https://www.readbyqxmd.com/read/28327419/concomitant-unilateral-post-traumatic-leg-and-foot-compartment-syndrome-in-a-5-years-old-child-case-report
#17
Aissam Elmhiregh, Adel El Feghih, Khaled Faraj
BACKGROUND: Compartment syndrome is one of the most serious orthopedic emergencies [4]. It is usually anticipated and looked at in every single orthopedic case. Early recognition and management of those cases are quite important in order to avoid the devastating consequences of such condition. CASE SUMMARY: This is a case report of a 5 years old child with concomitant unilateral leg and foot compartment syndrome after a roll over trauma. The patient was presented with significant leg and foot swelling, severe pain and absent distal pulses...
February 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28327299/subject-specific-musculoskeletal-modeling-in-the-evaluation-of-shoulder-muscle-and-joint-function
#18
Wen Wu, Peter V S Lee, Adam L Bryant, Mary Galea, David C Ackland
Upper limb muscle force estimation using Hill-type muscle models depends on musculotendon parameter values, which cannot be readily measured non-invasively. Generic and scaled-generic parameters may be quickly and easily employed, but these approaches do not account for an individual subject's joint torque capacity. The objective of the present study was to develop a subject-specific experimental testing and modeling framework to evaluate shoulder muscle and joint function during activities of daily living, and to assess the capacity of generic and scaled-generic musculotendon parameters to predict muscle and joint function...
November 7, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/28327184/catestatin-vasostatin-cortisol-and-pain-assessments-in-dogs-suffering-from-traumatic-bone-fractures
#19
Thanikul Srithunyarat, Ragnvi Hagman, Odd V Höglund, Mats Stridsberg, Ulf Olsson, Jeanette Hanson, Chalermkwan Nonthakotr, Anne-Sofie Lagerstedt, Ann Pettersson
BACKGROUND: Traumatic bone fractures cause moderate to severe pain, which needs to be minimized for optimal recovery and animal welfare, illustrating the need for reliable objective pain biomarkers for use in a clinical setting. The objectives of this study were to investigate catestatin (CST) and vasostatin (VS) concentrations as two new potential biomarkers, and cortisol concentrations, scores of the short form of the Glasgow composite measure pain scale (CMPS-SF), and visual analog scale (VAS) in dogs suffering from traumatic bone fractures before and after morphine administration in comparison with healthy dogs...
March 21, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28327058/extending-energy-optimization-in-goal-directed-aiming-from-movement-kinematics-to-joint-angles
#20
James J Burkitt, Raoul M Bongers, Digby Elliott, Steve Hansen, James L Lyons
Energy optimization in goal-directed aiming has been demonstrated as an undershoot bias in primary movement endpoint locations, especially in conditions where corrections to target overshoots must be made against gravity. Two-component models of upper limb movement have not yet considered how joint angles are organized to deal with the energy constraints associated with moving the upper limb in goal-directed aiming tasks. To address this limitation, participants performed aiming movements to targets in the up and down directions with the index finger and two types of rod extensions attached to the index finger...
March 2017: Journal of Motor Behavior
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