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https://www.readbyqxmd.com/read/28633458/causes-of-death-and-mortality-trends-of-all-individuals-reported-with-hiv-aids-in-israel-1985-2010
#1
Zohar Mor, Rivka Sheffer, Daniel Chemtob
Background: Highly active antiretroviral therapy (HAART) has changed life-expectancy and mortality trends among people living with HIV/AIDS (PLWHA) since 1996. This retrospective cohort study aimed to assess the mortality epidemiology of PLWHA in Israel and analyze the causes of death. Methods: This cohort study included all adult Israeli-citizens PLWHA between 1985 and 2010 and crossed matched with the Civil Registry to identify those who died. Death certificates were classified into AIDS or non-AIDS deaths related-causes...
June 17, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/28633116/spatial-and-temporal-variation-in-autochthonous-and-allochthonous-contributors-to-increased-organic-carbon-and-nitrogen-burial-in-a-plateau-lake
#2
Changchun Huang, Ling Yao, Yunlin Zhang, Tao Huang, Mingli Zhang, A-Xing Zhu, Hao Yang
Increased organic carbon and nitrogen accumulation rates (OCAR and ONAR) in lake sediment significantly regulate the global carbon cycle. However, the reasons for and contributors to the increased OCAR and ONAR are unclear. Seven sediment cores, collected in July 2014 from Dianchi Lake, China, were used to evaluate the effects of autochthonous and allochthonous sources on OCAR and ONAR. The results indicate that OCAR and ONAR increased by factors of 4.33 and 7.34 over the past hundred years (1900-2000), particularly after algal blooms began to occur frequently (beginning in the 1980s)...
June 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28631310/zinc-supplementation-for-the-treatment-of-measles-in-children
#3
REVIEW
Ajibola A Awotiwon, Olabisi Oduwole, Anju Sinha, Charles I Okwundu
BACKGROUND: Measles is an important cause of childhood morbidity and mortality globally, despite increasing vaccine coverage. Zinc plays a significant role in the maintenance of normal immunological functions, therefore supplements given to zinc-deficient children will increase the availability of zinc and could reduce measles-related morbidity and mortality. This is an update of a review first published in 2015. OBJECTIVES: To assess the effects of zinc supplementation in reducing morbidity and mortality in children with measles...
June 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28628281/genomic-analysis-of-melanoma-evolution-following-a-30-year-disease-free-interval
#4
Jerry J Miller, Kristopher A Lofgren, Sarah R Hughes, Steven E Cash, Paraic A Kenny
Ultra-late melanoma recurrence is infrequent, poorly understood and, in most cases, difficult to unambiguously distinguish from a new primary melanoma. We identified a patient with a second melanoma diagnosed after a 30 year disease-free interval, and sought to determine if this new lesion was a recurrence of the original melanoma. Here we report the genomic sequence analysis of the exomes of two melanoma lesions isolated from the same individual in 1985 and 2015, and their comparison to each other and to the germline DNA of the patient...
June 19, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28627229/cobicistat-versus-ritonavir-similar-pharmacokinetic-enhancers-but-some-important-differences
#5
Alice Tseng, Christine A Hughes, Janet Wu, Jason Seet, Elizabeth J Phillips
OBJECTIVE: To describe properties of cobicistat and ritonavir; compare boosting data with atazanavir, darunavir, and elvitegravir; and summarize antiretroviral and comedication interaction studies, with a focus on similarities and differences between ritonavir and cobicistat. Considerations when switching from one booster to another are discussed. DATA SOURCES: A literature search of MEDLINE was performed (1985 to April 2017) using the following search terms: cobicistat, ritonavir, pharmacokinetic, drug interactions, booster, pharmacokinetic enhancer, HIV, antiretrovirals...
June 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28626902/haemophilus-influenzae-oral-vaccination-for-preventing-acute-exacerbations-of-chronic-bronchitis-and-chronic-obstructive-pulmonary-disease
#6
REVIEW
Edward Teo, Kathleen Lockhart, Sai Navya Purchuri, Jennifer Pushparajah, Allan W Cripps, Mieke L van Driel
BACKGROUND: Chronic bronchitis and chronic obstructive pulmonary disease (COPD) are serious conditions in which patients are predisposed to viral and bacterial infections resulting in potentially fatal acute exacerbations. Chronic obstructive pulmonary disease is defined as a lung disease characterised by obstruction to lung airflow that interferes with normal breathing. Antibiotic therapy has not been particularly useful in eradicating bacteria such as non-typeable Haemophilus influenzae (NTHi) because they are naturally occurring flora of the upper respiratory tract in many people...
June 19, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28625648/contrasting-temporal-trends-in-lung-cancer-incidence-by-socioeconomic-status-among-women-in-new-south-wales-australia-1985-2009
#7
Xue Qin Yu, Qingwei Luo, Clare Kahn, Paul Grogan, Dianne L O'Connell, Ahmedin Jemal
OBJECTIVE: We examined long-term trends in lung cancer incidence for women by socioeconomic groups in New South Wales (NSW), Australia. METHODS: Data on lung cancer incidence for women were extracted from the NSW Cancer Registry database. We divided the study cohort into five quintiles according to an area-based index of education and occupation (IEO) and calculated annual age-standardised incidence rates by IEO quintile for the period 1985-2009. The age-standardised incidence ratio (SIR) was estimated for IEO quintiles and 5-year period of diagnosis using the highest IEO quintile as the reference...
June 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28625133/recent-advances-in-targeting-the-hiv-1-tat-tar-complex
#8
Fardokht A Abulwerdi, Stuart F J Le Grice
Following seminal discoveries by Rosen and co-workers in 1985, the HIV-1 TAR has emerged as one of the most extensively studied regulatory elements of the HIV-1 genome. Located adjacent to the long terminal repeat promoter, this cis-acting motif, in conjunction with the viral Tat protein, plays a critical role in viral genomic RNA synthesis via modification of the transcription complex. As such, the Tat/TAR axis has been the subject of intense efforts aimed at developing therapeutic interventions, directed against both the protein and nucleic acid components...
June 15, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28625009/modifications-in-the-treatment-of-advanced-laryngeal-cancer-throughout-the-last-30%C3%A2-years
#9
Jacinto García Lorenzo, Victoria Montoro Martínez, Antonio Rigo Quera, Alberto Codina Aroca, Montserrat López Vilas, Miquel Quer Agustí, Xavier León Vintró
In the last decades, the treatment schemes for patients with locally advanced laryngeal cancer have changed significantly. These changes may have an impact in the survival of these patients. Our objective is to review the treatments administered to patients with locally advanced larynx tumors during a period of 30 years in our institution and to evaluate the prognostic impact of the changes in treatment protocols. Retrospective analysis of a cohort of 830 consecutive patients with T3 or T4 laryngeal carcinomas diagnosed and treated between 1985 and 2014 with a minimum follow-up of 1...
June 17, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28621180/interview-with-derek-connolly
#10
Derek Leslie Connolly
Dr Derek Connolly speaks to Adam Price-Evans, Commissioning Editor of Future Cardiology: Derek Leslie Connolly is a Consultant Interventional Cardiologist at Birmingham City Hospital (UK). He qualified from the University of Edinburgh (UK) summa cum laude in Pharmacology in 1985 and in Medicine in 1988 where he was the Brunton Medalist. As a Carnegie scholar at the University of California San Diego (CA, USA) he saw the early promise of angioplasty and changed his career plan from cardiac surgery to coronary intervention...
June 16, 2017: Future Cardiology
https://www.readbyqxmd.com/read/28620113/cell-scientist-to-watch-mads-gyrd-hansen
#11
(no author information available yet)
Mads Gyrd-Hansen studied biochemistry at the University of Copenhagen and received his PhD in 2005 under the supervision of Marja Jäättelä at the Danish Cancer Society Research Centre. He then joined the laboratory of Pascal Meier at the Institute of Cancer Research in London to work on the inhibitor of apoptosis (IAP) proteins. Mads returned to Copenhagen in 2008 to the Biotech Research and Innovation Centre (BRIC) in a senior postdoctoral position with Morten Frödin, and subsequently started his own research group with a career-development fellowship from the Danish Research Councils as part of the laboratory of Niels Mailand at the Novo Nordisk Foundation Centre for Protein Research...
June 15, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28618100/characteristics-of-an-effective-nursing-clinical-instructor-the-state-of-the-science
#12
Angela Dawn Collier
AIM AND OBJECTIVES: The aim of this paper is to analyze the perceived characteristics of an effective nursing clinical instructor and methods for measure instructor effectiveness. This review also examined importance of characteristics based on student age. BACKGROUND: The clinical instructor has a vital role in clinical education. While the role may be well defined, the characteristics these instructors need to do their jobs effectively are not. DESIGN: An integrative review from 1985 to present using four key terms: nursing, clinical, teaching, and effectiveness...
June 15, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28614232/the-efficiency-and-safety-of-dexamethasone-for-pain-control-in-total-joint-arthroplasty-a-meta-analysis-of-randomized-controlled-trials
#13
Jian Meng, Lin Li
BACKGROUND: This meta-analysis aimed to evaluate the efficiency and safety of dexamethasone administration in total knee and hip arthroplasties. METHODS: Two researchers search the relevant studies independently including Embase (1980-017.04), PubMed (1966-017.04), ScienceDirect (1985-017.04), Web of Science (1950-2017.03), and Cochrane Library for potential relevant studies. After testing for heterogeneity between studies, data were aggregated for random-effects models when necessary...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28613408/pre-admission-antibiotics-for-suspected-cases-of-meningococcal-disease
#14
REVIEW
Thambu D Sudarsanam, Priscilla Rupali, Prathap Tharyan, Ooriapadickal Cherian Abraham, Kurien Thomas
BACKGROUND: Meningococcal disease can lead to death or disability within hours after onset. Pre-admission antibiotics aim to reduce the risk of serious disease and death by preventing delays in starting therapy before confirmation of the diagnosis. OBJECTIVES: To study the effectiveness and safety of pre-admission antibiotics versus no pre-admission antibiotics or placebo, and different pre-admission antibiotic regimens in decreasing mortality, clinical failure, and morbidity in people suspected of meningococcal disease...
June 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28611886/managing-acute-behavioural-disturbances-in-the-emergency-department-using-the-environment-policies-and-practices-a-systematic-review
#15
Tracey J Weiland, Sean Ivory, Jennie Hutton
INTRODUCTION: Effective strategies for managing acute behavioural disturbances (ABDs) within emergency departments (EDs) are needed given their rising occurrence and negative impact on safety, psychological wellbeing, and staff turnover. Non-pharmacological interventions for ABD management generally fall into four categories: environmental modifications; policies; practice changes; and education. Our objective was to systematically review the efficacy of strategies for ABD management within EDs that involved changes to environment, architecture, policy and practice...
June 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28610375/description-of-six-new-species-of-the-genus-ripeacma-lepidoptera-oecophoridae-from-china-with-a-checklist-of-the-world-species
#16
Suran Li, Shuxia Wang
Six new species of the genus Ripeacma Moriuti, Saito & Lewvanich, 1985 are described: R. rostratiformis sp. nov. from Hainan, R. angustizonalis sp. nov. from Guangdong, Guangxi and Hainan, R. fusoidea sp. nov. from Yunnan, R. lunata sp. nov. from Guizhou, R. ventilatiformis sp. nov. from Hong Kong and Hainan, and R. sentosa sp. nov. from Guangxi; three species are newly recorded for China: R. yaiensis Moriuti, Saito & Lewvanich, 1985, R. nangae Moriuti, Saito & Lewvanich, 1985 and R. tirawati Moriuti, Saito & Lewvanich, 1985...
May 16, 2017: Zootaxa
https://www.readbyqxmd.com/read/28610162/revalidation-of-i-platystigma-i-kennedy-1920-with-a-synopsis-of-the-i-quadratum-i-species-group-and-the-description-of-three-new-species-odonata-pseudostigmatidae
#17
Angelo B M Machado, Déborah S Soldati Lacerda
The genus Platystigma Kennedy, 1920 is revalidated based mainly on the third segment of the penis that is plate-like, whereas in the other Pseudostigmatidae it is a flagellum. Dijkstra et al (2014) have merged this family into the Coenagrionidae. However, we prefer to maintain the long-used name Pseudostigmatidae until more detailed phylogenetic studies with more sampling are done. Eight species are here considered in the genus, three of which are described as new: P. humaita, P. minimum and P. quadratum. The genus is divided in two species group, jocaste and quadratum, the latter studied here...
March 13, 2017: Zootaxa
https://www.readbyqxmd.com/read/28609968/-i-hersilia-i-i-aadi-i-pravalikha-srinivasulu-amp-srinivasulu-2014-a-junior-synonym-of-i-hersilia-savignyi-i-lucas-1836-araneae-hersiliidae
#18
John T D Caleb, G B Pravalikha, Benaiah Ebenezer Johnson, Mitemlu Manyu, Soreiphy Mungkung, Manu Thomas Mathai
The genus Hersilia was established by Audouin in 1826 with H. caudata Audouin, 1826 as the type species. It is the most speciose hersiliid genus presently comprising 79 described species worldwide (World Spider Catalog 2017, version 18). There are seven species known from India: H. aadi Pravalikha, Srinivasulu & Srinivasulu, 2014, H. longivulva Sen et al., 2010, H. orvakalensis Javed et al., 2010, H. savignyi Lucas, 1836, H. striata Wang & Yin, 1985, H. sumatrana (Thorell, 1890), H. tibialis Baehr & Baehr, 1993...
April 18, 2017: Zootaxa
https://www.readbyqxmd.com/read/28609921/first-report-of-the-genus-i-tettigonia-i-linnaeus-orthoptera-tettigoniidae-tettigoniinae-and-record-of-i-tettigonia-i-i-caudata-i-i-caudata-i-charpentier-1842-from-india
#19
Rajendra Nagar, R Swaminathan
The genus Tettigonia Linnaeus (Tettigoniidae; Tettigoniinae) with the type species, Gryllus (Tettigonia) viridissima Linnaeus, 1758 belongs to the tribe Tettigoniini, which is represented by 15 genera and 27 species worldwide (Cigliano et al., 2017). According to the annotated checklist, the subfamily Tettigoniinae includes the only tribe Platycleidini Brunner von Wattenwyl, 1893 with 2 genera and 3 species as reported from India by Shishodia et al. (2010). In a review of Orthoptera from the Eastern Palearctic region, the genus Tettigonia Linnaeus was reported by Storozhenko (1994); additionally, some new species of Tettigonia have been described by Ogawa (2003), Greenwalt and Rust (2014), Chobanov et al...
April 28, 2017: Zootaxa
https://www.readbyqxmd.com/read/28609864/species-of-wadicosa-araneae-lycosidae-a-new-species-from-madagascar
#20
Torbjörn Kronestedt
Since establishing the wolf spider genus Wadicosa Zyuzin, 1985 (Zyuzin 1985), eleven species have been accepted in it, either by transfer from Lycosa Latreille, 1804 or Pardosa C.L. Koch, 1847 or by original designation (WSC 2017). However, according to Kronestedt (1987), additional species wait to be formally transferred to Wadicosa. The genus is restricted to the Old World, with one species, Wadicosa jocquei Kronestedt, 2015, recently described from Madagascar and surrounding islands.
May 10, 2017: Zootaxa
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