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surgical oncology research

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https://www.readbyqxmd.com/read/27905372/-combined-surgery-for-locally-advanced-colorectal-cancer
#1
O I Kit, Yu A Gevorkyan, N V Soldatkina, E N Kolesnikov, V E Kolesnikov, M A Kozhushko, A V Dashkov
AIM: To study the types and early outcomes of combined interventions for locally advanced colorectal cancer. MATERIAL AND METHODS: Since 2009 four hundreds and ninety eight patients underwent surgery in the Rostov Research Institute of Oncology for locally advanced colorectal cancer. Most cases of surgical procedures on adjacent organs included resection of small intestine (23.69%), supravaginal hysterectomy (16.47%), resection of bladder (12.25%), total hysterectomy (11...
2016: Khirurgiia
https://www.readbyqxmd.com/read/27898067/the-need-for-multidisciplinarity-in-specialist-training-to-optimize-future-patient-care
#2
REVIEW
Alison C Tree, Victoria Harding, Aneel Bhangu, Venkatesh Krishnasamy, Dion Morton, Justin Stebbing, Bradford J Wood, Ricky A Sharma
Harmonious interactions between radiation, medical, interventional and surgical oncologists, as well as other members of multidisciplinary teams, are essential for the optimization of patient care in oncology. This multidisciplinary approach is particularly important in the current landscape, in which standard-of-care approaches to cancer treatment are evolving towards highly targeted treatments, precise image guidance and personalized cancer therapy. Herein, we highlight the importance of multidisciplinarity and interdisciplinarity at all levels of clinical oncology training...
November 29, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27896519/image-guidance-technology-and-the-surgical-resection-of-spinal-column-tumors
#3
REVIEW
Bhargav Desai, Jonathan Hobbs, Grant Hartung, Guoren Xu, Ziya L Gokaslan, Andreas Linninger, Ankit I Mehta
Precision imaging is paramount to achieving success in surgical resection of many spinal tumors, whether the goal involves guiding a surgical cure for primary tumors or improving neurological decompression for metastatic lesions. Pre-operatively, image visualization is intimately involved with defining a clear target and surgical planning. Intra-operatively, image-guidance technology allows for surgeons to maximize the probability for gross total resection of spinal cord tumors and minimize damage to adjacent structures...
November 28, 2016: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/27889271/assessment-of-perioperative-nutrition-practices-and-attitudes-a-national-survey-of-colorectal-and-gi-surgical-oncology-programs
#4
J D Williams, Paul E Wischmeyer
BACKGROUND: Implementation of evidence-based peri-operative nutrition in the U.S. is poorly described and hypothesized to be suboptimal. This study broadly describes practices and attitudes regarding nutrition screening/intervention in U.S. gastrointestinal and oncologic surgeons. METHODS: Nationwide nutritional practice survey of GI/Oncologic surgical faculty. RESULTS: Program response rates were 57% and 81% for colorectal and oncology fellowships, respectively...
November 17, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27864705/the-clinical-and-financial-impact-of-a-pediatric-surgical-neuro-oncology-clinical-trial
#5
Eric M Thompson, Sridharan Gururangan, Gerald Grant, Duane Mitchell, John H Sampson
Pediatric surgical trials are rare and the impact of such trials on the institutions in which they are conducted is unknown. The purpose of this study was to analyze the clinical and financial impact of The Re-MATCH trial, a Phase I clinical trial requiring the biopsy or resection of recurrent medulloblastoma or PNET for enrollment. Inpatient financial and clinical volume information was collected during the 3 years of trial enrollment and the years preceding and following it. The primary endpoints were the difference in direct contribution margin (DCM), or net gain, of study and non-study patients and the difference in surgical volume during the study and non-study periods...
November 18, 2016: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/27855106/the-ibra-2-immediate-breast-reconstruction-and-adjuvant-therapy-audit-study-protocol-for-a-prospective-national-multicentre-cohort-study-to-evaluate-the-impact-of-immediate-breast-reconstruction-on-the-delivery-of-adjuvant-therapy
#6
Rajiv Dave, Rachel O'Connell, Tim Rattay, Zoe Tolkien, Nicola Barnes, Joanna Skillman, Paula Williamson, Elizabeth Conroy, Matthew Gardiner, Adrian Harnett, Ciara O'Brien, Jane Blazeby, Shelley Potter, Chris Holcombe
INTRODUCTION: Immediate breast reconstruction (IBR) is routinely offered to improve quality of life for women with breast cancer requiring a mastectomy, but there are concerns that more complex surgery may delay the delivery of adjuvant oncological treatments and compromise long-term oncological outcomes. High-quality evidence, however, is lacking. iBRA-2 is a national prospective multicentre cohort study that aims to investigate the effect of IBR on the delivery of adjuvant therapy. METHODS AND ANALYSIS: Breast and plastic surgery centres in the UK performing mastectomy with or without (±) IBR will be invited to participate in the study through the trainee research collaborative network...
October 7, 2016: BMJ Open
https://www.readbyqxmd.com/read/27825699/implementation-of-a-standardized-electronic-tool-improves-compliance-accuracy-and-efficiency-of-trainee-to-trainee-patient-care-handoffs-after-complex-general-surgical-oncology-procedures
#7
Callisia N Clarke, Sameer H Patel, Ryan W Day, Sobha George, Colin Sweeney, Georgina Avaloa Monetes De Oca, Mohamed Ait Aiss, Elizabeth G Grubbs, Brian K Bednarski, Jeffery E Lee, Diane C Bodurka, John M Skibber, Thomas A Aloia
BACKGROUND: Duty-hour regulations have increased the frequency of trainee-trainee patient handoffs. Each handoff creates a potential source for communication errors that can lead to near-miss and patient-harm events. We investigated the utility, efficacy, and trainee experience associated with implementation of a novel, standardized, electronic handoff system. METHODS: We conducted a prospective intervention study of trainee-trainee handoffs of inpatients undergoing complex general surgical oncology procedures at a large tertiary institution...
November 5, 2016: Surgery
https://www.readbyqxmd.com/read/27822109/the-danish-neuro-oncology-registry
#8
REVIEW
Steinbjørn Hansen
AIM OF DATABASE: The Danish Neuro-Oncology Registry (DNOR) was established by the Danish Neuro-Oncology Group as a national clinical database. It was established for the purpose of supporting research and development in adult patients with primary brain tumors in Denmark. STUDY POPULATION: DNOR has registered clinical data on diagnostics and treatment of all adult patients diagnosed with glioma since January 1, 2009, which numbers approximately 400 patients each year...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27806156/reliability-and-photographic-equivalency-of-the-scar-cosmesis-assessment-and-rating-scar-scale-an-outcome-measure-for-postoperative-scars
#9
Jonathan Kantor
Importance: Until recently, no ideal valid, feasible, and reliable scar scale existed to effectively assess the quality of postoperative linear scars. The Scar Cosmesis Assessment and Rating (SCAR) scale was developed and validated as a tool to assess the quality of postoperative scars in clinical and research settings. Objective: To assess the reliability of using photographs in lieu of live patient scar rating assessments, and to determine the interrater and intrarater reliability of the SCAR scale...
November 2, 2016: JAMA Dermatology
https://www.readbyqxmd.com/read/27797436/radio-guided-sentinel-lymph-node-detection-and-lymph-node-mapping-in-invasive-urinary-bladder-cancer-a-prospective-clinical-study
#10
F Aljabery, I Shabo, Hans Olson, Oliver Gimm, Staffan Jahnson
OBJECTIVES: We investigated the possibility to detect sentinel nodes in patients with urinary bladder cancer (UBC) intra-operatively and whether the histopathological status of the identified sentinel nodes reflected that of the lymphatic field. PATIENTS AND METHODS: We studied 103 patients with UBC pathological stage T1-T4 who were treated with cystectomy and pelvic lymph node (LN) dissection during 2005-2011 at the Department of Urology, Linköping University Hospital...
October 31, 2016: BJU International
https://www.readbyqxmd.com/read/27795811/current-debate-in-the-oncologic-management-of-rectal-cancer
#11
REVIEW
Trish Millard, Paul R Kunk, Erika Ramsdale, Osama E Rahma
Despite the considerable amount of research in the field, the management of locally advanced rectal cancer remains a subject to debate. To date, effective treatment centers on surgical resection with the standard approach of total mesorectal resection. Radiation therapy and chemotherapy have been incorporated in order to decrease local and systemic recurrence. While it is accepted that a multimodality treatment regimen is indicated, there remains significant debate for how best to accomplish this in regards to order, dosing, and choice of agents...
October 15, 2016: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/27794404/limited-thymectomy-as-a-potential-alternative-treatment-option-for-early-stage-thymoma-a-multi-institutional-propensity-matched-study
#12
Kyoung Shik Narm, Chang Young Lee, Young Woo Do, Hee Suk Jung, Go Eun Byun, Jin Gu Lee, Dae Joon Kim, Yoohwa Hwang, In Kyu Park, Chang Hyun Kang, Young Tae Kim, Jong Ho Cho, Yong Soo Choi, Jhingook Kim, Yong Mog Shim, Su Kyung Hwang, Yong-Hee Kim, Dong Kwan Kim, Seung-Il Park, Kyung Young Chung
OBJECTIVES: For early-stage thymoma, complete thymectomy has classically been regarded as the standard treatment protocol. However, several studies have shown that limited thymectomy may be an alternative treatment option for thymoma. This study compared perioperative outcomes, survival, and recurrence rates between patients undergoing limited thymectomy and complete thymectomy. MATERIALS AND METHODS: Between January 2000 and December 2013, a total of 762 patients underwent thymectomy for stage I or II thymomas at four institutions participating in the Korean Association for Research on the Thymus...
November 2016: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/27754474/zero-ischaemia-partial-nephrectomy-a-call-for-standardized-nomenclature-and-functional-outcomes
#13
Ahmad Alenezi, Giacomo Novara, Alexander Mottrie, Salah Al-Buheissi, Omer Karim
Nephron-sparing surgery for the removal of small renal masses delivers equivalent oncological outcomes and better functional outcomes compared with those associated with radical nephrectomy. All contemporary partial nephrectomy techniques including open, laparoscopic and robotic approaches involve the use of hilar clamping in order to facilitate haemostasis, and to enable accurate tumour excision and parenchymal reconstruction. Zero ischaemia was subsequently introduced as a technique to eliminate the renal ischaemia induced by hilar clamping...
October 18, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27753784/when-less-is-more-the-indications-for-mis-techniques-and-separation-surgery-in-metastatic-spine-disease
#14
Scott L Zuckerman, Ilya Laufer, Arjun Sahgal, Yoshiya J Yamada, Meic H Schmidt, Dean Chou, John H Shin, Naresh Kumar, Daniel M Sciubba
STUDY DESIGN: Systematic review. OBJECTIVE: The aim of this study was to review the techniques, indications, and outcomes of minimally invasive surgery (MIS) and separation surgery with subsequent radiosurgery in the treatment of patients with metastatic spine disease. SUMMARY OF BACKGROUND DATA: The utilization of MIS techniques in patients with spine metastases is a growing area within spinal oncology. Separation surgery represents a novel paradigm where radiosurgery provides long-term control after tumor is surgically separated from the neural elements...
October 15, 2016: Spine
https://www.readbyqxmd.com/read/27752811/ergonomics-in-the-operating-room
#15
Shiromani Janki, Evalyn E A P Mulder, Jan N M IJzermans, T C Khe Tran
BACKGROUND: Since the introduction of minimally invasive surgery, surgeons appear to be experiencing more occupational musculoskeletal injuries. The aim of this study is to investigate the current frequency and effects of occupational musculoskeletal injuries on work absence. METHODS: An online questionnaire was conducted among all surgeons affiliated to the Dutch Society for Endoscopic Surgery, Gastrointestinal Surgery, and Surgical Oncology. In addition, this survey was conducted among surgeons, gynaecologists, and urologists of one cluster of training hospitals in the Netherlands...
October 17, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27720536/pathophysiology-and-contributing-factors-in-postprostatectomy-incontinence-a-review
#16
John Heesakkers, Fawzy Farag, Ricarda M Bauer, Jaspreet Sandhu, Dirk De Ridder, Arnulf Stenzl
CONTEXT: The incidence and awareness of postprostatectomy incontinence (PPI) has increased during the past few years, probably because of an increase in prostate cancer surgery. Many theories have been postulated to explain the pathophysiology of PPI. OBJECTIVE: The current review scrutinizes various pathophysiologic mechanisms underlying the occurrence of PPI. EVIDENCE ACQUISITION: A search was conducted on PubMed and EMBASE for publications on PPI...
October 6, 2016: European Urology
https://www.readbyqxmd.com/read/27708827/surgical-readmissions-results-of-integrating-pre-peri-and-postsurgical-care
#17
Katia Noyes, Janet Baack-Kukreja, Edward M Messing, Luke Schoeniger, Eva Galka, Wei Pan, Cai Xueya, Fergal J Fleming, John Rt Monson, Supriya G Mohile, Todd Francone
AIMS: To explore the feasibility of recruiting surgical oncology patients and implementing a surgical integrated discharge (SID) programme led by advanced practice providers (APP). BACKGROUND: Burden of illness and complexity of treatment regimen makes it challenging for surgical oncology patients to participate in research. Surgical oncology nurses may have the necessary expertise to overcome this problem. DESIGN: Controlled longitudinal prospective observational study...
July 2016: Nursing Open
https://www.readbyqxmd.com/read/27704226/impact-of-neoadjuvant-therapy-on-eligibility-for-and-frequency-of-breast-conservation-in-stage-ii-iii-her2-positive-breast-cancer-surgical-results-of-calgb-40601-alliance
#18
Mehra Golshan, Constance T Cirrincione, William M Sikov, Lisa A Carey, Donald A Berry, Beth Overmoyer, Nora L Henry, George Somlo, Elisa Port, Harold J Burstein, Clifford Hudis, Eric Winer, David W Ollila
OBJECTIVE: It had been previously shown that patients who receive neoadjuvant systemic therapy (NST) are more likely to undergo breast-conserving therapy (BCT) than those who have primary surgery. However, the frequency with which patients who are not BCT-eligible prior to NST convert to BCT-eligible with treatment is unknown. To document this conversion rate in a subset of patients expected to have a high clinical response rate to NST, we studied surgical assessment and management of patients enrolled on a randomized neoadjuvant trial for stage II-III HER2-positive breast cancer (HER2 + BC)(CALGB 40601)...
November 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27692834/localized-chromophobe-carcinomas-treated-by-nephron-sparing-surgery-have-excellent-oncologic-outcomes
#19
Pierre Bigot, Jean-Christophe Bernhard, Vincent Flamand, Inderbir Gill, Grégory Verhoest, Jean Baptiste Beauval, François Xavier Nouhaud, Evren Suer, Guillaume Ploussard, Jean François Hetet, Jérôme Rigaud, Eduard Baco, Stéphane Larré, Philippe Sebe, Nicolas Koutlidis, Aurélien Descazeaud, Masatoshi Eto, Arnaud Doerfler, Morgan Roupret, Nam Son Vuong, Boris Reix, Toru Matsugasumi, Adnan El Bakri, Laurence Albiges, Michel Soulié, Jean-Jacques Patard, Arnaud Méjean, Karim Bensalah
OBJECTIVE: To evaluate the oncologic outcomes of nephron-sparing surgery (NSS) for localized chromophobe renal cell carcinoma (cRCC). MATERIAL AND METHODS: We performed a multicenter international study involving the French Network for Research on Kidney Cancer (UroCCR) and 5 international teams. Data from 808 patients treated with NSS between 2004 and 2014 for non-clear cell RCCs were analyzed. RESULTS: We included 234 patients with cRCC...
September 27, 2016: Urologic Oncology
https://www.readbyqxmd.com/read/27678401/-hospital-volume-effects-in-surgical-treatment-of-gastric-cancer-results-of-a%C3%A2-prospective-multicenter-observational-study
#20
H Ptok, I Gastinger, F Meyer, A Ilsemann, H Lippert, C Bruns
BACKGROUND: The impact of hospital and surgeon volume on the treatment outcome based on data obtained from cohort and register studies has been controversially discussed in the international literature. The results of large-scale prospective observational studies within the framework of clinical healthcare research may lead to relevant recommendations in this ongoing discussion. MATERIAL AND METHODS: Within the framework of the prospective multicenter German Gastric Cancer Study 2 (QCGC 2), from 1 January 2007 to 31 December 2009 a total of 2897 patients with the histological diagnosis of gastric cancer from 140 surgical departments were registered and analyzed...
September 27, 2016: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
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