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Emergency medicie

Janet Lin, Sara Baghikar, Cammeo Mauntel-Medici, Sara Heinert, Daven Patel
OBJECTIVE: Emergency Departments (EDs) have implemented HIV screening using a variety of strategies. This study investigates how specific patient and health system factors in the ED impact who is and is not screened in a combined targeted and non-targeted, EMR-driven, opt-out, HIV screening program. METHODS: This was a retrospective, cross sectional study of ED visits where patients were determined eligible for HIV screening by an EMR algorithm between 11/18/2014 and 7/15/2015...
August 18, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
M G Glezer On Behalf Of The Forsage Program Participants
AIM: to assess adherence of patients to antihypertensive therapy with fixed perindopril and indapamide combination (FPIC) as well as to elucidate causes of changes of therapy after 6 months. MATERIAL AND METHODS: In 6 months after termination of the FORSAGE observational program we interviewed over telephone 148 of 1299 patients who achieved target blood pressure (BP) values. RESULTS: Adherence to treatment was high - 67.5% of patients continued to take the drug...
April 2017: Kardiologiia
Giovanni Maurizio Giammanco, Simona De Grazia, Floriana Bonura, Vincenzo Cappa, Sara Li Muli, Arcangelo Pepe, Maria Cristina Medici, Fabio Tummolo, Adriana Calderaro, Francesca Di Bernardo, Piera Dones, Anna Morea, Daniela Loconsole, Cristiana Catella, Valentina Terio, Krisztiàn Bànyai, Maria Chironna, Vito Martella
In winter 2015-16, norovirus GII.17 Kawasaki 2014 emerged as a cause of sporadic gastroenteritis in children in Italy. Median patient age was higher for those with GII.17 than GII.4 infection (55 vs. 24 months), suggesting limited cross-protection for older children.
July 2017: Emerging Infectious Diseases
Annalisa Ferretti, Daniele Malferrari, Luca Medici, Martina Savioli
Conodont elements are important archives of sea/pore water chemistry yet they often exhibit evidence of diagenetic mineral overgrowth which may be biasing measurents. We decided to investigate this phenomenon by characterising chemically and crystallographically, the original biomineral tissue and the diagenetic mineral nature of conodont elements from the Ordovician of Normandy. Diagenetic apatite crystals observed on the surface of conodont elements show distinctive large columnar, blocky or web-like microtextures...
May 9, 2017: Scientific Reports
Mahendra Rai, Avinash P Ingle, Priti Paralikar, Indarchand Gupta, Serenella Medici, Carolina A Santos
Malaria is one of the most common infectious diseases, which has become a great public health problem all over the world. Ineffectiveness of available antimalarial treatment is the main reason behind its menace. The failure of current treatment strategies is due to emergence of drug resistance in Plasmodium falciparum and drug toxicity in human beings. Therefore, the development of novel and effective antimalarial drugs is the need of the hour. Considering the huge biomedical applications of nanotechnology, it can be potentially used for the malarial treatment...
April 24, 2017: International Journal of Pharmaceutics
Gianluca Montanari Vergallo, Raffaella Rinaldi, Giuseppe Bersani, Enrico Marinelli
Negligence liability on the part of a psychiatrist belongs among high-complexity fields, for both the judge and his or her technical consultants. In most instances, there are no scientific grounds in order to ascribe with reasonable certainty liability to medical personnel and nursing staff, while often judges tend to stretch the concept of “protection” to a degree to which the psychiatrist is deemed to have a legal obligation to stave off the development of any adverse consequence which psychic distress may bring upon the patient...
January 2017: Rivista di Psichiatria
G La Rosa, S Della Libera, M Iaconelli, Y T R Proroga, D De Medici, V Martella, E Suffredini
Norovirus (NoV) is a major cause of non-bacterial acute gastroenteritis worldwide, and the variants of genotype GII.4 are currently the predominant human strains. Recently, a novel variant of NoV GII.17 (GII.P17_GII.17 NoV), termed Kawasaki 2014, has been reported as the cause of gastroenteritis outbreaks in Asia, replacing the pandemic strain GII.4 Sydney 2012. The GII.17 Kawasaki 2014 variant has also been reported sporadically in patients with gastroenteritis outside of Asia, including Italy. In this study, 384 shellfish samples were subjected to screening for human NoVs using real-time PCR and 259 (67...
March 3, 2017: Food and Environmental Virology
Sara Heinert, Julius Carter, Cammeo Mauntel-Medici, Janet Lin
Routine opt-out HIV screening is recommended for everyone between 13 and 64 years of age. An urban, academic emergency department implemented a nurse-driven routine opt-out HIV screening program. The aim of our study was to assess program uptake and opportunities to improve the program from the perspectives of emergency nurses. Emergency nurses completed a brief prediscussion questionnaire and then participated in a focus group or semi-structured one-on-one interview to elicit feedback on the routine opt-out HIV screening program...
May 2017: Journal of the Association of Nurses in AIDS Care: JANAC
Monica S Vavilala, Silvia B Lujan, Qian Qiu, Gustavo J Petroni, Nicolás M Ballarini, Nahuel Guadagnoli, María Alejandra Depetris, Gabriela A Faguaga, Gloria M Baggio, Leonardo O Busso, Mirta E García, Osvaldo R González Carrillo, Paula L Medici, Silvia S Sáenz, Elida E Vanella, Anthony Fabio, Michael J Bell
OBJECTIVE: There is little information on the type of early care provided to children with traumatic brain injury (TBI) in low middle income countries. We benchmarked early prehospital [PH] and emergency department [ED] pediatric TBI care in Argentina. METHODS: We conducted a secondary analysis of data from patients previously enrolled in a prospective seven center study of children with TBI. Eligible participants were patients 0-18 years, and had diagnosis of TBI (admission Glasgow Coma scale score [GCS] < 13 or with GCS 14-15 and abnormal head CT scan within 48 hours of admission, and head AIS > 0)...
2016: PloS One
Janet Lin, Cammeo Mauntel-Medici, Sara Heinert, Sara Baghikar
Emergency Departments (EDs) are important settings for routine HIV screening because they are safety nets for populations with limited access to primary care and high risk for HIV infection. However, EDs rarely perform routine HIV screening due to logistical barriers. An electronic medical record (EMR)-driven routine opt-out HIV screening program was implemented in an urban academic ED and led to rapid scale-up of screening volume and detection of unknown HIV infection. The streamlined tool, requiring 4 mouse clicks, automates screening for eligibility, facilitates documentation of consent and orders the HIV test...
May 2017: Journal of Public Health Management and Practice: JPHMP
Clara Reece Medici, Claus Høstrup Vestergaard, Dusan Hadzi-Pavlovic, Povl Munk-Jørgensen, Gordon Parker
BACKGROUND: Bipolar disorder is characterized by a seasonal pattern with emerging evidence that weather conditions may trigger symptoms. Thus, our aims were to investigate if year-to-year variations in admissions with mania correlated with year-to-year variations in key meteorological variables, if there was a secular trend in light of climate change and if gender or admission status influenced the seasonal pattern. METHODS: We undertook a Danish register-based nationwide historical cohort study...
November 15, 2016: Journal of Affective Disorders
Maria Cristina Medici, Fabio Tummolo, Vito Martella, Maria Cristina Arcangeletti, Flora De Conto, Carlo Chezzi, Alessandro Magrì, Enikő Fehér, Szilvia Marton, Adriana Calderaro, Krisztián Bányai
After a sporadic detection in 1990s, G3P[8] rotaviruses emerged as a predominant genotype during recent years in many areas worldwide, including parts of Italy. The present study describes the molecular epidemiology and evolution of G3P[8] rotaviruses detected in Italian children with gastroenteritis during two survey periods (2004-2005 and 2008-2013). Whole genome of selected G3P[8] strains was determined and antigenic differences between these strains and rotavirus vaccine strains were analyzed. Among 819 (271 in 2004-2005 and 548 in 2008-2013) rotaviruses genotyped during the survey periods, the number of G3P[8] rotavirus markedly varied over the years (0/83 in 2004, 30/188 in 2005 and 0/96 in 2008, 6/88 in 2009, 4/97 in 2010, 0/83 in 2011, 9/82 in 2012, 56/102 cases in 2013)...
June 2016: Infection, Genetics and Evolution
Roberto Bruni, Stefania Taffon, Michele Equestre, Paola Chionne, Elisabetta Madonna, Caterina Rizzo, Maria Elena Tosti, Valeria Alfonsi, Lara Ricotta, Dario De Medici, Simona Di Pasquale, Gaia Scavia, Enrico Pavoni, Marina Nadia Losio, Luisa Romanò, Alessandro Remo Zanetti, Anna Morea, Monia Pacenti, Giorgio Palù, Maria Rosaria Capobianchi, Maria Chironna, Maria Grazia Pompa, Anna Rita Ciccaglione
BACKGROUND: Foodborne Hepatitis A Virus (HAV) outbreaks are being recognized as an emerging public health problem in industrialized countries. In 2013 three foodborne HAV outbreaks occurred in Europe and one in USA. During the largest of the three European outbreaks, most cases occurred in Italy (>1,200 cases as of March 31, 2014). A national Task Force was established at the beginning of the outbreak by the Ministry of Health. Mixed frozen berries were early demonstrated to be the source of infection by the identity of viral sequences in patients and in food...
2016: PloS One
Natasha P Medici, Maurizio Del Poeta
Fungal infections are emerging as a major problem in part due to high mortality associated with systemic infections, especially in the case of immunocompromised patients. With the development of new treatments for diseases such as cancer and the acquired immune deficiency syndrome pandemic, the number of immunosuppressed patients has increased and, as a consequence, also the number of invasive fungal infections has increased. Several studies have proposed new strategies for the development of effective fungal vaccines...
December 2015: Memórias do Instituto Oswaldo Cruz
Maria Cristina Medici, Fabio Tummolo, Adriana Calderaro, Maria Chironna, Giovanni Maurizio Giammanco, Simona De Grazia, Maria Cristina Arcangeletti, Flora De Conto, Carlo Chezzi, Vito Martella
Surveillance of noroviruses in Italy identified the novel GII.17 human norovirus strain, Kawasaki 2014, in February 2015. This novel strain emerged as a major cause of gastroenteritis in Asia during 2014/15, replacing the pandemic GII.4 norovirus strain Sydney 2012, but being reported only sporadically elsewhere. This novel strain is undergoing fast diversification and continuous monitoring is important to understand the evolution of noroviruses and to implement the future strategies on norovirus vaccines.
2015: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
Raman Tanwar, Nikhil Khattar, Rajeev Sood, Arun Makkar
INTRODUCTION: Information derived from social media sources is being used to save lives and take vital life altering decisions. You Tube is one of the most widely used social media for seeking medical information. Quality of information available to patients and medical professionals on YouTube with regards to benign prostatic hyperplasia (BPH), a common urological condition, assessed. MATERIALS AND METHODS: First 1 00 videos results on BPH were analysed by three independent observers and graded based on the quality of information provided using an indigenous grading system of five points ranging from not useful to Informative for the Medical Professional...
July 2015: Recenti Progressi in Medicina
Maria Cristina Medici, Fabio Tummolo, Simona De Grazia, Adriana Calderaro, Flora De Conto, Valentina Terio, Maria Chironna, Floriana Bonura, Marzia Pucci, Kristián Bányai, Vito Martella, Giovanni Maurizio Giammanco
Norovirus (NoV) is one of the major causes of diarrhoeal disease with epidemic, outbreak and sporadic patterns in humans of all ages worldwide. NoVs of genotype GII.4 cause nearly 80-90 % of all NoV infections in humans. Periodically, some GII.4 strains become predominant, generating major pandemic variants. Retrospective analysis of the GII.4 NoV strains detected in Italy between 2007 and 2013 indicated that the pandemic variant New Orleans 2009 emerged in Italy in the late 2009, became predominant in 2010-2011 and continued to circulate in a sporadic fashion until April 2013...
September 2015: Journal of General Virology
Kenneth Beer, Richard G Glogau, Jeffrey S Dover, Ava Shamban, Lata Handiwala, Jason T Olin, Brian Bulley
OBJECTIVE: To compare the safety and effectiveness of small particle hyaluronic acid plus lidocaine (SPHAL) versus no treatment for lip augmentation and perioral rhytides. METHODS AND MATERIALS: Adults scoring 1 (very thin) to 2 (thin) on the Medicis Lip Fullness Scale (MLFS) for upper and lower lips were randomized (3:1) to SPHAL or no treatment. Treatment success was an MLFS increase ≥1 point at Week 8. Secondary end points (MLFS score, independent photographic review, Global Aesthetic Improvement Scale, Wrinkle Assessment Scale for Upper Lip Lines) and safety were assessed throughout...
April 2015: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Fabrizio Anniballi, Davide Lonati, Alfonsina Fiore, Bruna Auricchio, Dario De Medici, Carlo Alessandro Locatelli
Botulism is a severe neuroparalytic disease resulting from exposure to one of the most poisonous toxins to humans. Because of this high potency and the use of toxins as biological weapons, botulism is a public health concern and each case represents an emergency. Current therapy involves respiratory supportive care and anti-toxins administration. As a preventive measure, vaccination against toxins represents an effective strategy but is undesirable due the rarity of botulism and the effectiveness of toxins in treating several neuromuscular disorders...
September 2014: Expert Review of Anti-infective Therapy
Adriana Calderaro, Giovanna Piccolo, Chiara Gorrini, Sara Montecchini, Mirko Buttrini, Sabina Rossi, Maddalena Piergianni, Flora De Conto, Maria Cristina Arcangeletti, Carlo Chezzi, Maria Cristina Medici
BACKGROUND: Leptospirosis, a spirochaetal zoonotic disease of worldwide distribution, endemic in Europe, has been recognized as an important emerging infectious disease, though yet it is mostly a neglected disease which imparts its greatest burden on impoverished populations from developing countries. Leptospirosis is caused by the infection with any of the more than 230 serovars of pathogenic Leptospira sp. In this study we aimed to implement the MALDI-TOF mass spectrometry (MS) database currently available in our laboratory with Leptospira reference pathogenic (L...
2014: BMC Research Notes
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