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https://www.readbyqxmd.com/read/29776020/paramagnetic-colloids-chaotic-routes-to-clusters-and-molecules
#1
Hamed Abdi, Rasam Soheilian, Randall M Erb, Craig E Maloney
We present computer simulations and experiments on dilute suspensions of superparamagnetic particles subject to rotating magnetic fields. We focus on chains of four particles and their decay routes to stable structures. At low rates, the chains track the external field. At intermediate rates, the chains break up but perform a periodic (albeit complex) motion. At sufficiently high rates, the chains generally undergo chaotic motion at short times and decay to either closely packed clusters or more dispersed, colloidal molecules at long times...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29775823/plasticity-of-population-coding-in-primary-sensory-cortex
#2
REVIEW
Amy M LeMessurier, Daniel E Feldman
That experience shapes sensory tuning in primary sensory cortex is well understood. But effective neural population codes depend on more than just sensory tuning. Recent population imaging and recording studies have characterized population codes in sensory cortex, and tracked how they change with sensory manipulations and training on perceptual learning tasks. These studies confirm sensory tuning changes, but also reveal other features of plasticity, including sensory gain modulation, restructuring of firing correlations, and differential routing of information to output pathways...
May 15, 2018: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/29775481/widespread-anatoxin-a-detection-in-benthic-cyanobacterial-mats-throughout-a-river-network
#3
Keith Bouma-Gregson, Raphael M Kudela, Mary E Power
Benthic algae fuel summer food webs in many sunlit rivers, and are hotspots for primary and secondary production and biogeochemical cycling. Concerningly, riverine benthic algal assemblages can become dominated by toxic cyanobacteria, threatening water quality and public health. In the Eel River in Northern California, over a dozen dog deaths have been attributed to cyanotoxin poisonings since 2000. During the summers of 2013-2015, we documented spatial and temporal patterns of cyanotoxin concentrations in the watershed, showing widespread distribution of anatoxin-a in benthic cyanobacterial mats...
2018: PloS One
https://www.readbyqxmd.com/read/29775462/analytical-scaling-relations-to-evaluate-leakage-and-intrusion-in-intermittent-water-supply-systems
#4
David D J Taylor, Alexander H Slocum, Andrew J Whittle
Intermittent water supplies (IWS) deliver piped water to one billion people; this water is often microbially contaminated. Contaminants that accumulate while IWS are depressurized are flushed into customers' homes when these systems become pressurized. In addition, during the steady-state phase of IWS, contaminants from higher-pressure sources (e.g., sewers) may continue to intrude where pipe pressure is low. To guide the operation and improvement of IWS, this paper proposes an analytic model relating supply pressure, supply duration, leakage, and the volume of intruded, potentially-contaminated, fluids present during flushing and steady-state...
2018: PloS One
https://www.readbyqxmd.com/read/29775317/a-combined-sfg-and-thin-liquid-film-study-of-the-specific-effect-of-monovalent-cations-on-interfacial-water-structure
#5
Afshin Asadzadeh Shahir, Khristo Khristov, Khoi Tan Nguyen, Anh V Nguyen, Elena D Mileva
Some salts have been recently shown to decrease the SFG (sum frequency generation spectroscopy) intensity of the hydrogen-bonded water molecules, but a quantitative explanation is still awaited. Here we report a similar trend for the chloride salts of monovalent cations, i.e., LiCl, NaCl, and CsCl, at low concentrations. Specifically, we revealed not only the specific adsorption of cations at the water surface but also the concentration-dependent effect of ions on the SFG response of the interfacial water molecules...
May 18, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29774845/brucella-suis-infection-in-dog-fed-raw-meat-the-netherlands
#6
Marloes A M van Dijk, Marc Y Engelsma, Vanessa X N Visser, Marcel A H Spierenburg, Marjolijn E Holtslag, Peter T J Willemsen, Jaap A Wagenaar, Els M Broens, Hendrik I J Roest
A Brucella suis biovar 1 infection was diagnosed in a dog without typical exposure risks, but the dog had been fed a raw meat-based diet (hare carcasses imported from Argentina). Track and trace investigations revealed that the most likely source of infection was the dog's raw meat diet.
June 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29774379/-agenesis-of-the-corpus-callosum
#7
REVIEW
J M Lieb, F J Ahlhelm
CLINICAL ISSUE: Agenesis of the corpus callosum is reported to have an incidence of about 1:4000 live births. In 30-45% of cases, genetic etiologies can be identified, e. g., 10% chromosomal anomalies and 20-35% genetic syndromes. Environmental factors like fetal alcohol syndrome are also known to be prone to callosal agenesis. Callosal agenesis can be complete or partial and can be isolated or associated with other central nervous system (CNS) anomalies (e. g., cortical developmental disorders, callosal lipoma, intracranial cysts) or extra-CNS anomalies (e...
May 17, 2018: Der Radiologe
https://www.readbyqxmd.com/read/29774291/significant-decline-in-lymphatic-filariasis-associated-with-nationwide-scale-up-of-insecticide-treated-nets-in-zambia
#8
M Nsakashalo-Senkwe, E Mwase, E Chizema-Kawesha, V Mukonka, P Songolo, F Masaninga, M P Rebollo, B Thomas, M J Bockarie, H Betts, J R Stothard, L A Kelly-Hope
Lymphatic filariasis (LF) is a mosquito-borne disease, broadly endemic in Zambia, and is targeted for elimination by mass drug administration (MDA) of albendazole and diethylcarbamazine citrate (DEC) to at-risk populations. Anopheline mosquitoes are primary vectors of LF in Africa, and it is possible that the significant scale-up of malaria vector control over the past decade may have also impacted LF transmission, and contributed to a decrease in prevalence in Zambia. We therefore aimed to examine the putative association between decreasing LF prevalence and increasing coverage of insecticide-treated mosquito nets (ITNs) for malaria vector control, by comparing LF mapping data collected between 2003-2005 and 2009-2011 to LF sentinel site prevalence data collected between 2012 and 2014, before any anti-LF MDA was started...
November 2017: Parasite Epidemiology and Control
https://www.readbyqxmd.com/read/29773757/neural-signatures-of-the-processing-of-temporal-patterns-in-sound
#9
Björn Herrmann, Ingrid S Johnsrude
The ability to detect regularities in sound (i.e., recurring structure) is critical for effective perception, enabling, for example, change detection and prediction. Two seemingly unconnected lines of research concern the neural operations involved in processing regularities: one investigates how neural activity synchronizes with temporal regularities (e.g., frequency modulation; FM) in sounds, whereas the other focuses on increases in sustained activity during stimulation with repeating tone-frequency patterns...
May 17, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29773527/acceptability-and-feasibility-of-real-time-antiretroviral-therapy-adherence-interventions-in-rural-uganda-mixed-method-pilot-randomized-controlled-trial
#10
Angella Musiimenta, Esther C Atukunda, Wilson Tumuhimbise, Emily E Pisarski, Melanie Tam, Monique A Wyatt, Norma C Ware, Jessica E Haberer
BACKGROUND: Wireless electronic adherence monitors can detect antiretroviral therapy (ART) adherence lapses and trigger interventions in real time, thus potentially avoiding unnecessary HIV viremia. Evidence about the acceptability and feasibility of these monitors and associated interventions, however, is limited. OBJECTIVE: The aim of this study was to assess the acceptability and feasibility of real-time adherence monitoring linked to text messaging (short message service, SMS) reminders and notifications to support adherence among individuals living with HIV who are taking ART in rural southwestern Uganda...
May 17, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29772486/quantitative-microbial-risk-assessment-of-microbial-source-tracking-markers-in-recreational-water-contaminated-with-fresh-untreated-and-secondary-treated-sewage
#11
Warish Ahmed, Kerry A Hamilton, Aldo Lobos, Bridie Hughes, Christopher Staley, Michael J Sadowsky, Valerie J Harwood
Microbial source tracking (MST) methods have provided the means to identify sewage contamination in recreational waters, but the risk associated with elevated levels of MST targets such as sewage-associated Bacteroides HF183 and other markers is uncertain. Quantitative microbial risk assessment (QMRA) modeling allows interpretation of MST data in the context of the risk of gastrointestinal (GI) illness caused by exposure to known reference pathogens. In this study, five sewage-associated, quantitative PCR (qPCR) MST markers [Bacteroides HF183 (HF183), Methanobrevibacter smithii nifH (nifH), human adenovirus (HAdV), human polyomavirus (HPyV) and pepper mild mottle virus (PMMoV)] were evaluated to determine at what concentration these nucleic acid markers reflected a significant health risk from exposure to fresh untreated or secondary treated sewage in beach water...
May 14, 2018: Environment International
https://www.readbyqxmd.com/read/29771987/visualization-of-gender-race-citizenship-and-academic-performance-in-association-with-career-outcomes-of-15-year-biomedical-doctoral-alumni-at-a-public-research-university
#12
Ambika Mathur, Annmarie Cano, Michael Kohl, Nisansala S Muthunayake, Prassanna Vaidyanathan, Mary E Wood, Mustafa Ziyad
It has long been thought that biomedical doctoral students pursue careers primarily as tenure-track/tenured faculty at research institutions. Recent reports showed, however, that the majority of biomedical doctoral alumni engage in a variety of careers. Wayne State University (WSU) undertook a project to understand the career trajectories of its biomedical doctoral alumni to create programs to better prepare its students for careers in multiple pathways. Data were collected on career outcomes of WSU's biomedical doctoral alumni who graduated in a 15-year period from 1999-2014...
2018: PloS One
https://www.readbyqxmd.com/read/29771138/rate-of-upper-extremity-injury-in-high-school-baseball-pitchers-who-played-catcher-as-a-secondary-position
#13
Elizabeth E Hibberd, Sakiko Oyama, Joseph B Myers
CONTEXT:   Many high school pitchers play another position after they have finished pitching for the day or on their rest days from pitching. Because of the cumulative demands on the arm, pitchers who also play catcher may have a greater risk of developing a throwing-related shoulder or elbow injury. OBJECTIVE:   To compare the rate of throwing-related upper extremity injuries between high school baseball pitchers who also played catcher as a secondary position and those who did not play catcher...
May 17, 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29770910/creation-and-implementation-of-an-environmental-scan-to-assess-cancer-genetics-services-at-three-oncology-care-settings
#14
Erica M Bednar, Michael T Walsh, Ellen Baker, Kimberly I Muse, Holly D Oakley, Rebekah C Krukenberg, Cara S Dresbold, Sandra B Jenkinson, Amanda L Eppolito, Kelly B Teed, Molly H Klein, Nichole A Morman, Elizabeth C Bowdish, Pauline Russ, Emaline E Wise, Julia N Cooper, Michael W Method, John W Henson, Andrew V Grainger, Banu K Arun, Karen H Lu
An environmental scan (ES) is an efficient mixed-methods approach to collect and interpret relevant data for strategic planning and project design. To date, the ES has not been used nor evaluated in the clinical cancer genetics setting. We created and implemented an ES to inform the design of a quality improvement (QI) project to increase the rates of adherence to national guidelines for cancer genetic counseling and genetic testing at three unique oncology care settings (OCS). The ES collected qualitative and quantitative data from reviews of internal processes, past QI efforts, the literature, and each OCS...
May 16, 2018: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/29770603/t-cell-tracking-using-cerenkov-and-radioluminescence-imaging
#15
F Boschi, F De Sanctis, S Ugel, A E Spinelli
Cancer immunotherapy is a promising strategy based on the ability of the immune system to kill selected cells. In the development of an effective T-cell therapy the non-invasive cell tracking methods play a crucial role. Here we investigate the potentialities of T-cell marked with radionuclides in order to detect their localization with imaging techniques in small animal rodents. A protocol to label T-cells with 32 P-ATP was tested and evaluated. The homing of 32 P-ATP labeled T lymphocytes was investigated by Cerenkov luminescence imaging and radioluminescence imaging The first approach relies on the acquisition of Cerenkov photons produced by the beta particles emitted by the 32 P internalized by lymphocytes; the second one on the detection of photons coming from the conversion of radioactive energy in light done by scintillator crystals layered on the animals...
May 16, 2018: Journal of Biophotonics
https://www.readbyqxmd.com/read/29770257/toeplitz-inverse-covariance-based-clustering-of-multivariate-time-series-data
#16
David Hallac, Sagar Vare, Stephen Boyd, Jure Leskovec
Subsequence clustering of multivariate time series is a useful tool for discovering repeated patterns in temporal data. Once these patterns have been discovered, seemingly complicated datasets can be interpreted as a temporal sequence of only a small number of states, or clusters . For example, raw sensor data from a fitness-tracking application can be expressed as a timeline of a select few actions ( i.e. , walking, sitting, running). However, discovering these patterns is challenging because it requires simultaneous segmentation and clustering of the time series...
August 2017: KDD: Proceedings
https://www.readbyqxmd.com/read/29769100/what-did-the-go4health-policy-research-project-contribute-to-the-policy-discourse-on-the-sustainable-development-goals-a-reflexive-review
#17
REVIEW
Vannarath Te, Nadia Floden, Sameera Hussain, Claire E Brolan, Peter S Hill
BACKGROUND: In 2012, the European Commission funded Go4Health-Goals and Governance for Global Health, a consortium of 13 academic research and human rights institutions from both Global North and South-to track the evolution of the Sustainable Development Goals (SDGs), and provide ongoing policy advice. This paper reviews the research outputs published between 2012 and 2016, analyzing the thematic content of the publications, and the influence on global health and development discourse through citation metrics...
May 16, 2018: Globalization and Health
https://www.readbyqxmd.com/read/29768069/analyzing-trend-for-u-s-immigrants-e-health-engagement-from-2008-to-2013
#18
Xinyan Zhao, Bo Yang, Chau-Wai Wong
Our study examines the trend of U.S. immigrants' engagement in various e-health activities and how immigrants' use of e-health technologies is associated with their cultural characteristics over years. Aggregating three national representative samples of U.S. immigrants from the Health Information National Trends Survey (HINTS) conducted between 2008 and 2013, our results from trend analyses and logistic regressions revealed that the U.S. immigrants exhibited an increasing trend on two types of e-health engagement: tracking personal health information online and communicating with a doctor online...
May 16, 2018: Health Communication
https://www.readbyqxmd.com/read/29767209/chemically-non-perturbing-sers-detection-of-a-catalytic-reaction-with-black-silicon
#19
E Mitsai, A Kuchmizhak, E Pustovalov, A Sergeev, A Mironenko, S Bratskaya, D P Linklater, A Balčytis, E Ivanova, S Juodkazis
All-dielectric resonant micro- and nano-structures made of high-index dielectrics have recently emerged as a promising surface-enhanced Raman scattering (SERS) platform which can complement or potentially replace the metal-based counterparts in routine sensing measurements. These unique structures combine the highly-tunable optical response and high field enhancement with the non-invasiveness, i.e. chemically non-perturbing the analyte, simple chemical modification and recyclability. Meanwhile, commercially competitive fabrication technologies for mass production of such structures are still missing...
May 16, 2018: Nanoscale
https://www.readbyqxmd.com/read/29765018/tracking-hiv-1-recombination-to-resolve-its-contribution-to-hiv-1-evolution-in-natural-infection
#20
Hongshuo Song, Elena E Giorgi, Vitaly V Ganusov, Fangping Cai, Gayathri Athreya, Hyejin Yoon, Oana Carja, Bhavna Hora, Peter Hraber, Ethan Romero-Severson, Chunlai Jiang, Xiaojun Li, Shuyi Wang, Hui Li, Jesus F Salazar-Gonzalez, Maria G Salazar, Nilu Goonetilleke, Brandon F Keele, David C Montefiori, Myron S Cohen, George M Shaw, Beatrice H Hahn, Andrew J McMichael, Barton F Haynes, Bette Korber, Tanmoy Bhattacharya, Feng Gao
Recombination in HIV-1 is well documented, but its importance in the low-diversity setting of within-host diversification is less understood. Here we develop a novel computational tool (RAPR (Recombination Analysis PRogram)) to enable a detailed view of in vivo viral recombination during early infection, and we apply it to near-full-length HIV-1 genome sequences from longitudinal samples. Recombinant genomes rapidly replace transmitted/founder (T/F) lineages, with a median half-time of 27 days, increasing the genetic complexity of the viral population...
May 15, 2018: Nature Communications
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