keyword
https://read.qxmd.com/read/38601966/synthesis-of-pyrodextrins-and-enzymatically-resistant-maltodextrins-from-makal-xanthosoma-yucatenensis-starch
#1
JOURNAL ARTICLE
Enrique Barbosa-Martín, Enrique Sauri-Duch, Luis Chel-Guerrero, Luis Cuevas-Glory, Víctor Moo-Huchin, David Betancur-Ancona
RESEARCH BACKGROUND: Enzymatically resistant maltodextrins (ERM) are a resistant starch type 4, synthesized from native starch. They are obtained by the sequential application of two processes: pyrodextrinization, which produces pyrodextrins, and enzymatic hydrolysis, which produces ERM. In these processes atypical bonds are formed that confer pyrodextrins and ERM similar properties to dietary fiber, such as resistance to digestion. The aim of this work is to determine and evaluate some physicochemical properties of pyrodextrins and ERM obtained from native starch isolated from makal ( Xanthosoma yucatanense ) tubers...
March 2024: Food Technology and Biotechnology
https://read.qxmd.com/read/38582143/combinatorial-metabolic-engineering-of-bacillus-subtilis-for-de-novo-production-of-polymyxin-b
#2
JOURNAL ARTICLE
Hui-Zhong Sun, Qing Li, Wei Shang, Bin Qiao, Qiu-Man Xu, Jing-Sheng Cheng
Polymyxin is a lipopeptide antibiotic that is effective against multidrug-resistant Gram-negative bacteria. However, its clinical development is limited due to low titer and the presence of homologs. To address this, the polymyxin gene cluster was integrated into Bacillus subtilis, and sfp from Paenibacillus polymyxa was expressed heterologously, enabling recombinant B. subtilis to synthesize polymyxin B. Regulating NRPS domain inhibited formation of polymyxin B2 and B3. The production of polymyxin B increased to 329...
April 4, 2024: Metabolic Engineering
https://read.qxmd.com/read/38475281/functionalization-methods-of-starch-and-its-derivatives-from-old-limitations-to-new-possibilities
#3
REVIEW
Arkadiusz Zarski, Kamila Kapusniak, Sylwia Ptak, Magdalena Rudlicka, Sergiu Coseri, Janusz Kapusniak
It has long been known that starch as a raw material is of strategic importance for meeting primarily the nutritional needs of people around the world. Year by year, the demand not only for traditional but also for functional food based on starch and its derivatives is growing. Problems with the availability of petrochemical raw materials, as well as environmental problems with the recycling of post-production waste, make non-food industries also increasingly interested in this biopolymer. Its supporters will point out countless advantages such as wide availability, renewability, and biodegradability...
February 21, 2024: Polymers
https://read.qxmd.com/read/38455215/inulin-type-fructans-with-different-degrees-of-polymerization-improve-insulin-resistance-metabolic-parameters-and-hormonal-status-in-overweight-and-obese-women-with-polycystic-ovary-syndrome-a-randomized-double-blind-placebo-controlled-clinical-trial
#4
JOURNAL ARTICLE
Rahele Ziaei, Zahra Shahshahan, Hatav Ghasemi-Tehrani, Zahra Heidari, Marilyn S Nehls, Reza Ghiasvand
Polycystic ovary syndrome (PCOS) is associated with reproductive disorders and adverse cardiometabolic risk factors that can negatively impact the general health of women. Inulin-type fructans (ITFs) are proposed to beneficially affect risk factors associated with metabolic disorders. Whether ITFs can help with the management of PCOS by modifying insulin resistance (IR) and androgen levels has not yet been explored. The aim of this study was to investigate the effects of ITFs with different degrees of polymerization on insulin resistance, blood lipids, anthropometric measures, and hormonal status in overweight and obese women with PCOS...
March 2024: Food Science & Nutrition
https://read.qxmd.com/read/38452710/fabrication-of-high-preformance-emulsifier-from-conjugating-maltodextrin-onto-myofibrillar-protein-peptide-with-microwave-ultrasound-synergy
#5
JOURNAL ARTICLE
Zhiyu Li, Xiaomei Zhong, Cuirong Luan, Nanhua Wen, Chuanyang Shi, Xiaoyu Lin, Chao Zhao, Yang Zhang, Lianyu Luo, Liang Zhang, Yijing Wu, Jie Yang
In this study, we systematically investigated the emulsifying capabilities of myofibrillar protein (MP)- and MP peptide (MPP)-based conjugates synthesized through intensification techniques: water bath (WB), microwave, ultrasound, and the combined ultrasound-microwave (UM) methods. Compared with WB, microwave, and ultrasound treatments, the combined UM treatment greatly promoted the glycation reaction because ultrasound and microwave mutually reinforced modification effects. The resultant conjugate structure tended to unfold with more flexible conformation and homogeneous morphology...
February 20, 2024: Ultrasonics Sonochemistry
https://read.qxmd.com/read/38414081/the-mechanistic-role-of-natural-antimicrobials-in-preventing-staphylococcus-aureus-invasion-of-mac-t-cells-using-an-in-vitro-mastitis-model
#6
JOURNAL ARTICLE
Igori Balta, David McCleery, Saida Roxana Feier David, Elena Pet, Ducu Stef, Tiberiu Iancu, Ioan Pet, Lavinia Stef, Nicolae Corcionivoschi
BACKGROUND: Starting primarily as an inflammation of the mammary gland, mastitis is frequently driven by infectious agents such as Staphylococcus aureus. Mastitis has a large economic impact globally, which includes diagnostic, treatment, and the production costs not to mention the potential milk contamination with antimicrobial residues. Currently, mastitis prevention and cure depends on intramammary infusion of antimicrobials, yet, their overuse risks engendering resistant pathogens, posing further threats to livestock...
February 27, 2024: Irish Veterinary Journal
https://read.qxmd.com/read/38400033/improved-viability-of-spray-dried-pantoea-agglomerans-for-phage-carrier-mediated-control-of-fire-blight
#7
JOURNAL ARTICLE
Nassereldin Ibrahim, Darlene Nesbitt, Qian Tracy Guo, Janet Lin, Antonet Svircev, Qi Wang, Joel T Weadge, Hany Anany
Fire blight, caused by Erwinia amylovora , is a devastating bacterial disease that threatens apple and pear production. It is mainly controlled by using antibiotics, such as streptomycin. Due to development of E. amylovora resistant strains and the excessive agricultural use of antibiotics, there is an increased awareness of the possibility of antibiotic resistance gene transfer to other microbes. Urgent development of biocontrol agents (BCAs) is needed that can be incorporated into integrated pest management programs as antibiotic alternatives...
February 6, 2024: Viruses
https://read.qxmd.com/read/38231993/a-comparative-study-of-resistant-dextrins-and-resistant-maltodextrins-from-different-tuber-crop-starches
#8
JOURNAL ARTICLE
Xinyang Chen, Yinchen Hou, Zhen Wang, Aimei Liao, Long Pan, Mingyi Zhang, Yingchun Xue, Jingjing Wang, Yingying Liu, Jihong Huang
The anti-digestibility of resistant dextrin (RD) and resistant maltodextrin (RMD) is usually significantly affected by processing techniques, reaction conditions, and starch sources. The objective of this investigation is to elucidate the similarities and differences in the anti-digestive properties of RD and RMD prepared from three different tuber crop starches, namely, potato, cassava, and sweet potato, and to reveal the associated mechanisms. The results show that all RMDs have a microstructure characterized by irregular fragmentation and porous surfaces, no longer maintaining the original crystalline structure of starches...
November 27, 2023: Polymers
https://read.qxmd.com/read/38225116/maltodextrin-binding-protein-as-a-key-factor-in-cronobacter-sakazakii-survival-under-desiccation-stress
#9
JOURNAL ARTICLE
Juan Xue, Jun Lv, Lanfang Liu, Fangfang Duan, Aiying Shi, Xuemeng Ji, Li Ding
Cronobacter sakazakii (C. sakazakii) is a notorious pathogen responsible for infections in infants and newborns, often transmitted through contaminated infant formula. Despite the use of traditional pasteurization methods, which can reduce microbial contamination, there remains a significant risk of pathogenic C. sakazakii surviving due to its exceptional stress tolerance. In our study, we employed a comparative proteomic approach by comparing wild-type strains with gene knockout strains to identify the essential genes crucial for the successful survival of C...
February 2024: Food Research International
https://read.qxmd.com/read/38218728/determination-of-seven-human-milk-oligosaccharides-hmo-in-infant-formula-and-adult-nutritionals-first-action-2022-07
#10
JOURNAL ARTICLE
Thierry Bénet, Nathalie Frei, Véronique Spichtig, Denis Cuany, Sean Austin
BACKGROUND: Human milk oligosaccharides (HMOs) are important components of breast milk and may be responsible for some of the benefits of breastfeeding, including resistance to infections and the development of a healthy gut microbiota. Selected HMOs are now available for addition to infant formula, and suitable methods to control the dosing rate are needed. OBJECTIVE: To develop and validate a suitable method for the analysis of HMOs in infant formula. METHOD: A method was developed for the determination of seven human milk oligosaccharides (2'-fucosyllactose, 3-fucosyllactose, 3'-sialyllactose, 6'-sialyllactose (6'SL), 2',3-difucosyllactose, lacto-N-tetraose (LNT), lacto-N-neotetraose (LNnT)) in infant formula and adult nutritionals...
January 13, 2024: Journal of AOAC International
https://read.qxmd.com/read/38075926/development-of-a-new-broad-spectrum-microencapsulation-based-spray-drying-formulation-of-bacillus-thuringiensis-subsp-kurstaki-imbl-b9-for-the-control-of-moths
#11
JOURNAL ARTICLE
Kalaiselvi Duraisamy, Nan Hee Yu, Seon Hwa Kim, Jong Hwi Baek, Ji Yeon Son, Euna Choi, Min Gu Park, Jiwon Kim, Jae Young Choi, Mee Kyung Sang, Yeon Ho Je, Jin-Cheol Kim
Certain Bacillus thuringiensis (Bt) strains such as Bt subsp. kurstaki and Bt subsp. aizawai have been widely used for pest management in agricultural practices. However, each strain only shows high specificity for pest control against a narrow range of lepidopteran species, and numerous lepidopteran pests have developed resistance to commercialized Bt strains. Therefore, there is a need for the development of novel Bt bioinsecticides which allow for potent and broad-spectrum insecticidal activity against lepidopteran species, including Spodoptera spp...
2023: Frontiers in Microbiology
https://read.qxmd.com/read/38039382/slow-digestible-starch-in-native-pea-starch-pisum-sativum-l-lowers-glycemic-response-with-no-adverse-effects-on-gastrointestinal-symptoms-in-healthy-adults
#12
JOURNAL ARTICLE
Caroline Perreau, Fabrice Desailly, Sophie Grard, Pariyarath Sangeetha Thondre, Lis Ahlstrom, Jonathan Tammam, Daniel Wils
Diabetes prevalence achieved 470B in 2021. Diabetics are looking for foods that allow them to better manage the postprandial glycemia. Owing to its large amylose fraction, pea starch may contribute to formulate recipes with a lower glycemic index (GI). This study measured the rapidly, slowly digested and resistant fractions in pea starch and in a powder mix recipe. Starch fractions were determined according to the Englyst methodology. A nonblind repeat measure crossover design trial in healthy humans was used to study the GI of pea starch and maltodextrin powder mix recipes against glucose...
October 2023: Journal of Medicinal Food
https://read.qxmd.com/read/38032277/gastrointestinal-tolerability-and-acute-glycemic-response-of-oligosaccharides-and-polysaccharides-from-cellulose-and-xylan-in-healthy-adults-two-double-blinded-randomized-controlled-cross-over-trials
#13
JOURNAL ARTICLE
Daniela Moura de Oliveira Beltrame, Thomas Joseph Simmons, Alexandra L Jenkins, Timothy Dinan, Thomas Joseph Nicholson
OBJECTIVE: The aim of this study was to investigate the gastrointestinal tolerability, glycemic and insulinemic responses of Plant Fiber Extract (PFE), a mixture comprising of oligosaccharides and polysaccharides derived from cellulose and xylan. METHODS: Two double-blind, randomized, controlled, cross-over trials were conducted in healthy adults. In the first trial, participants ( n  = 29) consumed either 25, 35 or 45 g per day of PFE or resistant maltodextrin (Control) for 14 days...
November 30, 2023: J Am Nutr Assoc
https://read.qxmd.com/read/38018533/creatine-supplementation-and-resistance-training-in-patients-with-breast-cancer-cartic-study-protocol-for-a-randomized-controlled-trial
#14
JOURNAL ARTICLE
Aitor Martinez Aguirre-Betolaza, Jon Cacicedo, Arkaitz Castañeda-Babarro
BACKGROUND/AIMS: Creatine supplementation is an effective ergogenic nutrient for athletes, as well as for people starting a health or fitness program. Resistance training has previously been identified as an important method of increasing muscle mass and strength, especially in people with cancer to avoid sarcopenia. The potential of creatine supplementation for adaptations produced by resistance training in patients with cancer is still unknown. The primary aim of this study is to evaluate the effectiveness of a supervised resistance training program intervention with and without creatine supplementation in patients with breast cancer...
November 29, 2023: American Journal of Clinical Oncology
https://read.qxmd.com/read/38004611/carbohydrate-core-shell-electrosprayed-microcapsules-for-enhanced-oxidative-stability-of-vitamin-a-palmitate
#15
JOURNAL ARTICLE
Elnaz Z Fallahasghari, Marie Højgaard Lynge, Emma Espholin Gudnason, Kristin Munkerup, Ana C Mendes, Ioannis S Chronakis
Vitamin A is an essential micronutrient that is readily oxidized. In this study, the encapsulation of vitamin A palmitate (AP) within a core-shell carbohydrate matrix by co-axial electrospray and its oxidative stability was evaluated. The electrosprayed core-shell microcapsules consisted of a shell of octenyl succinic anhydride (OSA) modified corn starch, maltose (Hi-Cap), and a core of ethyl cellulose-AP (average diameter of about 3.7 µm). The effect of different compounds (digestion-resistant maltodextrin, soy protein hydrolysate, casein protein hydrolysate, and lecithin) added to the base core-shell matrix formulation on the oxidative stability of AP was investigated...
November 16, 2023: Pharmaceutics
https://read.qxmd.com/read/37976739/crosslinking-alginate-at-water-in-water-pickering-emulsions-interface-to-control-the-interface-structure-and-enhance-the-stress-resistance-of-the-encapsulated-probiotics
#16
JOURNAL ARTICLE
Yunxiao Xie, Cui Liu, Jie Zhang, Yan Li, Bin Li, Shilin Liu
HYPOTHESIS: The strategies for stabilizing water-in-water (W/W) emulsions include the adsorption of solid particles at the water-water interface and the generation of interfacial films. We hypothesize that if sodium alginate is crosslinked at the water-water interface of W/W Pickering emulsions, the microstructure and rheological properties of the emulsions could be improved, thus enhancing the activity of encapsulated probiotics in simulated gastrointestinal digestion. EXPERIMENTS: The W/W Pickering emulsions comprised a dispersed maltodextrin (MD) phase in a continuous hydroxypropyl methylcellulose (HPMC) phase...
November 2, 2023: Journal of Colloid and Interface Science
https://read.qxmd.com/read/37959144/sensory-evaluation-physico-chemical-properties-and-aromatic-profile-of-pasteurised-orange-juice-with-resistant-maltodextrin
#17
JOURNAL ARTICLE
Elías Arilla, Javier Martínez-Monzó, Maria Simona Chiş, Anca Corina Fǎrcaş, Sonia Ancuţa Socaci, Pilar Codoñer-Franch, Purificación García-Segovia, Marta Igual
The beneficial health effects of prebiotics have been demonstrated in numerous research papers. However, their incorporation into daily food remains unfamiliar to consumers. This work evaluates the effects of the addition of resistant maltodextrin (RMD) on the sensory attributes of pasteurised orange juice, together with the physico-chemical properties and the aromatic profile. RMD addition increased the sweetness and decreased the acidity and bitterness, resulting in a higher overall panellists' rating of orange juice...
November 3, 2023: Foods (Basel, Switzerland)
https://read.qxmd.com/read/37944409/metabolic-effects-of-an-oral-carbohydrate-whey-protein-supplement-after-fasting-in-volunteers-a-randomized-controlled-crossover-trial
#18
JOURNAL ARTICLE
Paulo L B Nogueira, Cristiane Coimbra de Paula, Diana Borges Dock-Nascimento, José Eduardo de Aguilar-Nascimento
OBJECTIVE: Oral supplements containing carbohydrates (CHOs) can be used to reduce preoperative fasting time. The aim of this study was to investigate the early metabolic and acute phase responses to a clear, oral supplement containing CHO and whey protein (WP) in young, healthy volunteers during a fasting-induced organic response. METHODS: In this controlled crossover clinical trial, volunteers were randomized into groups after a 12-h fast: the CHO+WP group consumed 200 mL CHO enriched with WP (n = 30); the CHO group members consumed 200 mL water plus maltodextrin (n = 30), and the Fast group was fasted only (n = 30)...
October 4, 2023: Nutrition
https://read.qxmd.com/read/37933983/liposomal-antibiotic-booster-potentiates-carbapenems-for-combating-ndms-producing-escherichia-coli
#19
JOURNAL ARTICLE
Sixuan Wu, Yongbin Wei, Yang Wang, Zhenzhong Zhang, Dejun Liu, Shangshang Qin, Jinjin Shi, Jianzhong Shen
Infections caused by Enterobacterales producing New Delhi Metallo-β-lactamases (NDMs), Zn(II)-dependent enzymes hydrolyzing carbapenems, are difficult to treat. Depriving Zn(II) to inactivate NDMs is an effective solution to reverse carbapenems resistance in NDMs-producing bacteria. However, specific Zn(II) deprivation and better bacterial outer membrane penetrability in vivo are challenges. Herein, authors present a pathogen-primed liposomal antibiotic booster (M-MFL@MB), facilitating drugs transportation into bacteria and removing Zn(II) from NDMs...
November 7, 2023: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/37929031/ameliorating-effects-of-l-carnitine-and-synbiotic-co-supplementation-on-anthropometric-measures-and-cardiometabolic-traits-in-women-with-obesity-a-randomized-controlled-clinical-trial
#20
RANDOMIZED CONTROLLED TRIAL
Farnoush Fallah, Reza Mahdavi
BACKGROUND: Obesity, a multifactorial disorder with pandemic dimensions, is conceded a major culprit of morbidity and mortality worldwide, necessitating efficient therapeutic strategies. Nutraceuticals and functional foods are considered promising adjuvant/complementary approaches for weight management in individuals with obesity who have low adherence to conventional treatments. Current literature supports the weight-reducing efficacy of pro/pre/synbiotics or L-carnitine; however, the superiority of the nutraceutical joint supplementation approach over common single therapies to counter obesity and accompanying comorbidities is well documented...
2023: Frontiers in Endocrinology
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