Anna Cavazza, Evangelos Triantafyllou, Roberto Savoldelli, Salma Mujib, Ellen Jerome, Francesca M Trovato, Florent Artru, Roosey Sheth, Xiao Hong Huang, Yun Ma, Francesco Dazzi, Tasneem Pirani, Charalambos G Antoniades, William M Lee, Mark J McPhail, Constantine J Karvellas
BACKGROUND AND AIMS: Acute liver failure is a multisystem disorder with a high mortality and frequent need for emergency liver transplantation. Following massive innate immune system activation, soluble markers of macrophage activation are released during liver damage and their association with disease severity and prognosis requires exploration. METHODS: Patients ALF from the United States Acute Liver Failure Study Group (USALFSG, n = 224) and King's College Hospital (n = 40) together with healthy controls (HC, n = 50) were recruited...
April 8, 2024: Liver International: Official Journal of the International Association for the Study of the Liver