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https://www.readbyqxmd.com/read/28647929/vitamin-d-status-among-israeli-medical-residents
#1
Hadar Moran-Lev, Dror Mandel, Yosef Weisman, Amit Ovental, Ronit Lubetzky
BACKGROUND: Israel is a country with a sunny climate; however, vitamin D deficiency and insufficiency are common findings in certain populations whose exposure to sunlight is limited. Medical residency is known for long indoor working hours, thus theoretically limiting the opportunities for sun exposure. OBJECTIVES: To evaluate whether the vitamin D status among residents in a single medical center in Tel Aviv is below the normal range. METHODS: Forty-six residents (28 females, 18 males, average age 33...
June 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28647914/shifting-the-physical-inactivity-curve-worldwide-by-closing-the-gender-gap
#2
Grégore I Mielke, Inacio Crochemore M da Silva, Tracy L Kolbe-Alexander, Wendy J Brown
PURPOSE: The aims of this study were to (i) examine gender differences in physical inactivity in countries with different levels of Human Development Index (HDI); and (ii) assess whether small changes in the prevalence of inactivity in women could achieve the World Health Organization's (WHO) global inactivity target. METHODS: Data on inactivity were extracted for 142 countries for the year 2010 from the WHO Data Repository. Data for HDI were obtained for the year 2010 from the United Nations Development Program...
June 24, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28647887/connexins-and-pannexins-in-bone-and-skeletal-muscle
#3
REVIEW
Lilian I Plotkin, Hannah M Davis, Bruno A Cisterna, Juan C Sáez
PURPOSE OF REVIEW: To discuss current knowledge on the role of connexins and pannexins in the musculoskeletal system. RECENT FINDINGS: Connexins and pannexins are crucial for the development and maintenance of both bone and skeletal muscle. In bone, the presence of connexin and more recently of pannexin channels in osteoblasts, osteoclasts, and osteocytes has been described and shown to be essential for normal skeletal development and bone adaptation. In skeletal muscles, connexins and pannexins play important roles during development and regeneration through coordinated regulation of metabolic functions via cell-to-cell communication...
June 24, 2017: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/28647879/disposal-of-household-pharmaceuticals-in-insular-communities-social-attitude-behaviour-evaluation-and-prevention-activities
#4
Antonis A Zorpas, Maria Dimitriou, Irene Voukkali
The increase in medicine and drug consumption have resulted in identifying these emerging pollutants in all aquatic compartments, ranging from surface water and groundwater resources to the marine environment. Pharmaceuticals are an indispensable part of life today. A large number of pharmaceuticals are used in a daily basis in the treatment, prevention, cure or diagnosis of diseases or to otherwise enhance people's physical or mental well-being. This paper focuses on the evaluation of the attitude of citizens in Cyprus regarding the disposal of pharmaceuticals as well as to identify the main reasons why pharmaceutical wastes are produced...
June 25, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28647869/muscular-viscoelastic-characteristics-of-athletes-participating-in-the-european-master-indoor-athletics-championship
#5
Marco Gervasi, Davide Sisti, Stefano Amatori, Marco Andreazza, Piero Benelli, Piero Sestili, Marco Bruno Luigi Rocchi, Anna Rita Calavalle
PURPOSE: To investigate how the viscoelastic characteristics of muscles (non-neural tone, elasticity and stiffness) vary as a function of age and gender in a sample of track and field master athletes. To compare these findings with data on related sedentary subjects in literature. METHODS: A total of 390 athletes (aged 35-99) were assessed during the European Master Athletics Indoor Championship 2016. A non-invasive measurement device called MyotonPro was used to measure tone, stiffness, and elasticity in the biceps brachii and rectus femoris muscles at rest...
June 24, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28647867/the-effects-of-4-weeks-stretching-training-to-the-point-of-pain-on-flexibility-and-muscle-tendon-unit-properties
#6
Pornpimol Muanjai, David A Jones, Mantas Mickevicius, Danguole Satkunskiene, Audrius Snieckus, Renata Rutkauskaite, Dalia Mickeviciene, Sigitas Kamandulis
PURPOSE: The purpose of this study was to compare the benefits and possible problems of 4 weeks stretching when taken to the point of pain (POP) and to the point of discomfort (POD). METHODS: Twenty-six physically active women (20 ± 1.1 years) took part in group-based stretching classes of the hamstring muscles, 4 times per week for 4 weeks, one group one stretching to POD, the other to POP. Passive stiffness, joint range of motion (ROM), maximal isometric torque and concentric knee flexion torque, were measured before training and 2 days after the last training session...
June 24, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28647727/patients-as-partners-in-enhanced-recovery-after-surgery-a-qualitative-patient-led-study
#7
Chelsia Gillis, Marlyn Gill, Nancy Marlett, Gail MacKean, Kathy GermAnn, Loreen Gilmour, Gregg Nelson, Tracy Wasylak, Susan Nguyen, Edamil Araujo, Sandra Zelinsky, Leah Gramlich
OBJECTIVES: Explore the experience of patients undergoing colorectal surgery within an Enhanced Recovery After Surgery (ERAS) programme. Use these experiential data to inform the development of a framework to support ongoing, meaningful patient engagement in ERAS. DESIGN: Qualitative patient-led study using focus groups and narrative interviews. Data were analysed iteratively using a Participatory Grounded Theory approach. SETTING: Five tertiary care centres in Alberta, Canada, following the ERAS programme...
June 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28647573/focal-adhesion-kinase-signaling-regulates-anti-inflammatory-function-of-bone-marrow-mesenchymal-stromal-cells-induced-by-biomechanical-force
#8
Hyun Jung Lee, Miguel F Diaz, Adesuwa Ewere, Scott D Olson, Charles S Cox, Pamela L Wenzel
Mesenchymal stromal cells (MSCs) have tremendous potential for use in regenerative medicine due to their multipotency and immune cell regulatory functions. Biomimetic physical forces have been shown to direct differentiation and maturation of MSCs in tissue engineering applications; however, the effect of force on immunomodulatory activity of MSCs has been largely overlooked. Here we show in human bone marrow-derived MSCs that wall shear stress (WSS) equivalent to the fluid frictional force present in the adult arterial vasculature significantly enhances expression of four genes that mediate MSC immune regulatory function, PTGS2, HMOX1, IL1RN, and TNFAIP6...
June 21, 2017: Cellular Signalling
https://www.readbyqxmd.com/read/28647551/factors-predicting-falls-and-mobility-outcomes-in-patients-with-stroke-returning-home-after-rehabilitation-who-are-at-risk-of-falling
#9
Mandy Man-Di Ng, Keith D Hill, Frances Batchelor, Elissa Burton
OBJECTIVE: To identify factors predicting falls and limited mobility in people with stroke at 12 months after returning home from rehabilitation. DESIGN: Observational cohort study with 12 month follow-up. SETTING: Community. PARTICIPANTS: People with stroke (n=144) and increased falls risk discharged home from rehabilitation. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Falls were measured using monthly calendars completed by participants, and mobility was assessed using gait speed over five metres (high mobility (>0...
June 21, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28647543/healthy-eating-and-activity-across-the-lifespan-heal-a-call-to-action-to-integrate-research-clinical-practice-policy-and-community-resources-to-address-weight-related-health-disparities
#10
Jerica M Berge, Margaret Adamek, Caitlin Caspi, Katie A Loth, Amy Shanafelt, Steven D Stovitz, Amanda Trofholz, Katherine Y Grannon, Marilyn S Nanney
Despite intense nationwide efforts to improve healthy eating and physical activity across the lifespan, progress has plateaued. Moreover, health inequities remain. Frameworks that integrate research, clinical practice, policy, and community resources to address weight-related behaviors are needed. Implementation and evaluation of integration efforts also remain a challenge. The purpose of this paper is to: (1) Describe the planning and development process of an integrator entity, HEAL (Healthy Eating and Activity across the Lifespan); (2) present outcomes of the HEAL development process including the HEAL vision, mission, and values statements; (3) define the planned integrator functions of HEAL; and (4) describe the ongoing evaluation of the integration process...
June 21, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28647443/dermal-and-transdermal-delivery-of-pharmaceutically-relevant-macromolecules
#11
REVIEW
S Münch, J Wohlrab, R H H Neubert
The skin offers an attractive way for dermal and transdermal drug delivery that is why the drug still needs certain qualities to transcend the outermost layer of the skin, the stratum corneum. The requirements are: drugs with a maximum molecular weight of 1kDa, high lipophilicity and a certain polarity. This would restrict the use of a transdermal delivery of macromolecules, which would make the drug more effective in therapeutic administration. Various studies have shown that macromolecules without support do not penetrate the human skin...
June 21, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28647435/dietary-habits-in-parkinson-s-disease-adherence-to-mediterranean-diet
#12
Erica Cassani, Michela Barichella, Valentina Ferri, Giovanna Pinelli, Laura Iorio, Carlotta Bolliri, Serena Caronni, Samanta A Faierman, Antonia Mottolese, Chiara Pusani, Fatemeh Monajemi, Marianna Pasqua, Alessandro Lubisco, Emanuele Cereda, Gianni Pezzoli
INTRODUCTION: Our objective is to describe the dietary habits, food preferences and adherence to Mediterranean diet (MeDi) of a large sample of Italian Parkinson's Disease (PD) patients compared to a group of controls. METHODS: Dietary habits of 600 PD patients from throughout Italy and 600 controls matched by gender, age, education, physical activity level and geographical residence, were collected using the ON-GP Food Frequency Questionnaire. Then, we compared patients by disease duration and the presence of swallowing disturbances...
June 15, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28647404/patient-centered-outcomes-and-treatment-preferences-regarding-sexual-problems-a-qualitative-study-among-midlife-women
#13
Holly N Thomas, Megan Hamm, Rachel Hess, Sonya Borrero, Rebecca C Thurston
BACKGROUND: Sexual dysfunction is common in midlife women and can have a significant negative impact on quality of life. Although treatments exist, there is little research on which sexual function outcomes and treatments midlife women prefer. AIM: To better understand the sexual function outcomes that were most important to sexually active women 45 to 60 years old and the types of treatments they would prefer from individual interviews and focus groups. METHODS: Twenty individual interviews and three focus groups (N = 39) were led by a trained facilitator, audio recorded, and transcribed...
June 21, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28647323/mechanism-of-plant-mediated-synthesis-of-silver-nanoparticles-a-review-on-biomolecules-involved-characterisation-and-antibacterial-activity
#14
REVIEW
S Rajeshkumar, L V Bharath
Engineering a reliable and eco-accommodating methodology for the synthesis of metal nanoparticles is a crucial step in the field of nanotechnology. Plant-mediated synthesis of metal nanoparticles has been developed as a substitute to defeat the limitations of conventional synthesis approaches such as physical and chemical methods. Biomolecules, such as proteins, amino acids, enzymes, flavonoids, and terpenoids from several plant extracts have been used as a stabilising and reducing agents for the synthesis of AgNPs...
June 21, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28647303/the-predictors-of-metabolic-syndrome-based-on-walker-health-promoting-lifestyle-in-iran-2016
#15
REVIEW
Maryam Mohammadi, Ali Ramezankhani, Shabnam Mohammadi, Shakiba Zahed, Farahnaz Khabiri, Soheila Khodakarim, Mohsen Roshani, Majid Ghayur
BACKGROUND: Understanding the metabolic syndrome has been the center of attention in recent years as a major risk factor of many diseases. Given the rising incidence of this disease and as the patient can compete against this disease with choosing healthy lifestyle, in the present study, we investigated the predictors of metabolic syndrome, based on Walker's health-promoting lifestyle in two large cities in Iran, in 2016. METHODS: This cross-sectional study used two-stage cluster sampling to select 1128 patients, among patients who referred to health centers in Isfahan and Yazd...
May 17, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28647296/multiple-stressors-including-contaminant-exposure-and-parasite-infection-predict-spleen-mass-and-energy-expenditure-in-breeding-ring-billed-gulls
#16
Sarah C Marteinson, David J Marcogliese, Jonathan Verreault
Daily energy expenditure (DEE) in animals is influenced by many factors although the impact of stressors remains largely unknown. The objective of this study was to determine how multiple physiological stressors (parasite infection and contaminant exposure) and natural challenges (energy-demanding activities and weather conditions) may affect DEE in nesting ring-billed gulls (Larus delawarensis) exposed to high concentrations of persistent organic contaminants (POPs). Physical activity, temperature, gastrointestinal parasitic worm abundance, relative spleen mass, plasma thyroid hormone levels and liver concentrations of POPs were determined; field metabolic rate (FMR) was used as a measure of DEE...
June 21, 2017: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/28647291/genistein-supplementation-improves-insulin-resistance-and-inflammatory-state-in-non-alcoholic-fatty-liver-patients-a-randomized-controlled-trial
#17
Sasan Amanat, Mohammad Hassan Eftekhari, Mohammad Fararouei, Kamran Bagheri Lankarani, Seyed Jalil Massoumi
BACKGROUND & AIMS: The beneficial effect of genistein has indicated on metabolic disorders and inflammatory state. The aim of this study was to investigate the effect of genistein supplementation on non-alcoholic fatty liver disease (NAFLD) as the hepatic manifest of metabolic syndrome. METHODS: In the present randomized double-blind controlled trial, patients with NAFLD were daily supplemented with either 250 mg genistein (n = 41) or placebo (n = 41) for 8-weeks...
June 1, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28647221/effect-of-thermo-tolerant-actinomycetes-inoculation-on-cellulose-degradation-and-the-formation-of-humic-substances-during-composting
#18
Yi Zhao, Yue Zhao, Zhechao Zhang, Yuquan Wei, Huan Wang, Qian Lu, Yanjie Li, Zimin Wei
The inoculum containing four cellulolytic thermophilic actinomycetes was screened from compost samples, and was inoculated into co-composting during different inoculation phases. The effect of different inoculation phases on cellulose degradation, humic substances formation and the relationship between inoculation and physical-chemical parameters was determined. The results revealed that inoculation at different phases of composting improved cellulase activities, accelerated the degradation of cellulose, increased the content of humic substances and influenced the structure of actinomycetic community, but there were significant differences between different inoculation phases...
June 21, 2017: Waste Management
https://www.readbyqxmd.com/read/28646935/five-year-results-of-the-prospective-randomized-controlled-prostatic-urethral-l-i-f-t-study
#19
Claus G Roehrborn, Jack Barkin, Steven N Gange, Neal D Shore, Jonathan L Giddens, Damien M Bolton, Barrett E Cowan, Anthony L Cantwell, Kevin T McVary, Alexis E Te, Shahram S Gholami, William G Moseley, Peter T Chin, William T Dowling, Sheldon J Freedman, Peter F Incze, K Scott Coffield, Sean Herron, Prem Rashid, Daniel B Rukstalis
INTRODUCTION: To report the five year results of a prospective, multi-center, randomized, blinded sham control trial of the Prostatic Urethral Lift (PUL) in men with bothersome lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: At 19 centers in North America and Australia, 206 subjects ≥ 50 years old with International Prostate Symptom Score (IPSS ) > 12, peak flow rate (Qmax) ≤ 12 mL/s, and prostate volume 30 cc-80 cc were randomized 2:1 to the PUL procedure or blinded sham control...
June 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28646889/apps-to-improve-diet-physical-activity-and-sedentary-behaviour-in-children-and-adolescents-a-review-of-quality-features-and-behaviour-change-techniques
#20
Stephanie Schoeppe, Stephanie Alley, Amanda L Rebar, Melanie Hayman, Nicola A Bray, Wendy Van Lippevelde, Jens-Peter Gnam, Philip Bachert, Artur Direito, Corneel Vandelanotte
BACKGROUND: The number of commercial apps to improve health behaviours in children is growing rapidly. While this provides opportunities for promoting health, the content and quality of apps targeting children and adolescents is largely unexplored. This review systematically evaluated the content and quality of apps to improve diet, physical activity and sedentary behaviour in children and adolescents, and examined relationships of app quality ratings with number of app features and behaviour change techniques (BCTs) used...
June 24, 2017: International Journal of Behavioral Nutrition and Physical Activity
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