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Paternal support in pregnancy

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https://www.readbyqxmd.com/read/28535307/intergenerational-impact-of-paternal-lifetime-exposures-to-both-folic-acid-deficiency-and-supplementation-on-reproductive-outcomes-and-imprinted-gene-methylation
#1
Lundi Ly, Donovan Chan, Mahmoud Aarabi, Mylène Landry, Nathalie A Behan, Amanda J MacFarlane, Jacquetta Trasler
STUDY QUESTION: Do paternal exposures to folic acid deficient (FD), and/or folic acid supplemented (FS) diets, throughout germ cell development adversely affect male germ cells and consequently offspring health outcomes? SUMMARY ANSWER: Male mice exposed over their lifetimes to both FD and FS diets showed decreased sperm counts and altered imprinted gene methylation with evidence of transmission of adverse effects to the offspring, including increased postnatal-preweaning mortality and variability in imprinted gene methylation...
May 23, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28464725/the-development-and-application-of-a-protocol-for-the-writing-assessing-and-validating-of-a-corpus-of-relationship-focused-text-messages-for-new-and-expecting-fathers
#2
Chris D May, Richard Fletcher
In developed countries, antenatal education aims to reduce difficulties that mothers and fathers experience during transition to parenthood. However, fathers are often distracted from preparing themselves by the attention given to preparing and supporting mothers. Developments in digital communication present alternative means of supporting fathers at this time. Studies, across a range of health concerns, have reported successful outcomes from text-based interventions. Text messaging, focusing on the issues that cause paternal distress at this time, could provide timely, targeted, and effective support to fathers in their transition to parenthood...
May 1, 2017: Health Informatics Journal
https://www.readbyqxmd.com/read/28443481/impact-of-abnormal-dna-methylation-of-imprinted-loci-on-human-spontaneous-abortion
#3
Yudong Liu, Yan Tang, Desheng Ye, Weixu Ma, Shuxian Feng, Xuelan Li, Xingyu Zhou, Xin Chen, Shiling Chen
Currently, there is a growing concern regarding the safety of assisted reproductive technology (ART) due to increased risk of spontaneous abortion (SA) and imprinting disorders in ART-conceived offspring. Early investigations suggested that aberrant genetic imprinting may be related to pregnancy loss; however, few studies have used human tissue specimens. Here the DNA methylation patterns of 3 imprinted genes, including maternally inherited GRB10 and the paternally inherited IGF2 and PEG3 genes, were evaluated in human chorionic villus samples by pyrosequencing and bisulfite sequencing polymerase chain reaction...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28398993/prevention-of-hiv-in-adolescent-girls-and-young-women-key-to-an-aids-free-generation
#4
Quarraisha Abdool Karim, Cheryl Baxter, Deborah Birx
The Global Plan towards the elimination of new HIV infections among children by 2015 and keeping their mothers alive (Global Plan) has ensured that more infants in high-HIV burden countries survive childhood HIV-free. Although equal numbers of boy and girl children have survived to age 10, a gender divergence starts to emerge as they enter adolescence. Up to 3 times as many young women aged 15-24 years in eastern and southern Africa are living with HIV compared with their male peers. Further, more adolescent girls and young women are sick and/or dying from AIDS-related or HIV-related complications during pregnancy and in the postpartum period, underscoring the importance of strengthening HIV treatment and prevention services for this group...
May 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28397798/telomere-length-in-newborns-is-related-to-maternal-stress-during-pregnancy
#5
T Send, M Gilles, V Codd, I A C Wolf, S Bardtke, F Streit, J Strohmaier, J Frank, D Schendel, M W Sütterlin, M Denniff, M Laucht, N J Samani, M Deuschle, M Rietschel, S H Witt
Telomere length (TL) is a marker of biological aging, and numerous studies have shown associations between TL and somatic or psychiatric disorders. Research also indicates an association between maternal stress during pregnancy and TL in the offspring. The present study investigated possible associations between TL and: (1) maternal perceived stress during pregnancy; (2) a maternal life-time history of psychiatric disorder (life-time PD); and (3) paternal age. TL was analysed in 319 newborns and 318 mothers from a predominantly Caucasian sample (n=273 Caucasian newborns and n=274 Causasian mothers)...
April 11, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28346297/exposure-to-mycophenolate-and-fatherhood
#6
Karsten Midtvedt, Stein Bergan, Anna Varberg Reisæter, Bjørn Egil Vikse, Anders Åsberg
BACKGROUND: Mycophenolic acid (MPA) is the active immunosuppressive substance in both mycophenolate mofetil and mycophenolate sodium and it is widely used after organ transplantation. In females taking MPA is teratogenic and may also influence spermatogenesis. There is a lack of knowledge regarding outcome of pregnancies fathered by males exposed to MPA. METHODS: We compared outcomes in pregnancies fathered by renal transplant males per whether they had been exposed to MPA or not at time of conception...
March 22, 2017: Transplantation
https://www.readbyqxmd.com/read/28327118/sociodemographic-and-delivery-risk-factors-for-developing-postpartum-depression-in-a-sample-of-3233-mothers-from-the-czech-elspac-study
#7
Adam Fiala, Jan Švancara, Jana Klánová, Tomáš Kašpárek
BACKGROUND: In the postpartum period, certain groups of women are at a higher risk for developing depressive episodes. Several studies have described risk factors for developing postpartum depression (PPD). However, these studies have used limited numbers of participants, and therefore the estimated prevalence of PPD varies greatly. METHODS: The objective of this study is to identify the main risk factors for developing PPD by using data collected via the Czech version of the European Longitudinal Study of Pregnancy and Childhood (ELSPAC)...
March 21, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28241183/association-of-gestational-weight-gain-and-maternal-body-mass-index-in-early-pregnancy-with-risk-for-nonaffective-psychosis-in-offspring
#8
Euan Mackay, Christina Dalman, Håkan Karlsson, Renee M Gardner
Importance: Prenatal exposure to famine is associated with a 2-fold risk for nonaffective psychoses. Less is known about whether maternal nutrition states during pregnancy modify offspring risk for nonaffective psychoses in offspring in well-fed populations. Objective: To determine whether gestational weight gain (GWG) during pregnancy and maternal body mass index (BMI) in early pregnancy are associated with risk for nonaffective psychoses in offspring. Design, Setting and Participants: This population-based cohort study used data from Swedish health and population registers to follow up 526 042 individuals born from January 1, 1982, through December 31, 1989, from 13 years of age until December 31, 2011...
April 1, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28203641/the-antecedents-of-women-s-external-locus-of-control-associations-with-characteristics-of-their-parents-and-their-early-childhood
#9
Jean Golding, Steven Gregory, Yasmin Iles-Caven, Stephen Nowicki
Locus of control (LOC) measures individuals' expectancies regarding their ability to affect what happens to them based on how they behave. The more they believe their behaviour has something to do with what happens to them the more internal they are. In contrast the more they perceive that what happens to them is beyond their control and determined by luck, fate, chance or powerful others the more external they are. Copious research findings suggest that external LOC (ELOC) is associated with many adverse personal, social, academic and health outcomes...
January 2017: Heliyon
https://www.readbyqxmd.com/read/28173760/grandparental-immune-priming-in-the-pipefish-syngnathus-typhle
#10
Anne Beemelmanns, Olivia Roth
BACKGROUND: Phenotypic changes in response to environmental influences can persist from one generation into the next. In many systems parental parasite experience influences offspring immune responses, known as transgenerational immune priming (TGIP). TGIP in vertebrates is mainly maternal and short-term, supporting the adaptive immune system of the offspring during its maturation. However, if fathers and offspring have a close physical connection, evolution of additional paternal immune priming can be adaptive...
February 7, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28125983/fathers-views-and-experiences-of-their-own-mental-health-during-pregnancy-and-the-first-postnatal-year-a-qualitative-interview-study-of-men-participating-in-the-uk-born-and-bred-in-yorkshire-baby-cohort
#11
Z Darwin, P Galdas, S Hinchliff, E Littlewood, D McMillan, L McGowan, S Gilbody
BACKGROUND: The prevalence of fathers' depression and anxiety in the perinatal period (i.e. from conception to 1 year after birth) is approximately 5-10%, and 5-15%, respectively; their children face increased risk of adverse emotional and behavioural outcomes, independent of maternal mental health. Critically, fathers can be protective against the development of maternal perinatal mental health problems and their effects on child outcomes. Preventing and treating paternal mental health problems and promoting paternal psychological wellbeing may therefore benefit the family as a whole...
January 26, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28118352/using-genetic-variation-to-explore-the-causal-effect-of-maternal-pregnancy-adiposity-on-future-offspring-adiposity-a-mendelian-randomisation-study
#12
Rebecca C Richmond, Nicholas J Timpson, Janine F Felix, Tom Palmer, Romy Gaillard, George McMahon, George Davey Smith, Vincent W Jaddoe, Debbie A Lawlor
BACKGROUND: It has been suggested that greater maternal adiposity during pregnancy affects lifelong risk of offspring fatness via intrauterine mechanisms. Our aim was to use Mendelian randomisation (MR) to investigate the causal effect of intrauterine exposure to greater maternal body mass index (BMI) on offspring BMI and fat mass from childhood to early adulthood. METHODS AND FINDINGS: We used maternal genetic variants as instrumental variables (IVs) to test the causal effect of maternal BMI in pregnancy on offspring fatness (BMI and dual-energy X-ray absorptiometry [DXA] determined fat mass index [FMI]) in a MR approach...
January 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28043372/relationships-among-stallion-fertility-and-semen-traits-using-estimated-breeding-values-of-german-warmblood-stallions
#13
Maren Gottschalk, Harald Sieme, Gunilla Martinsson, Ottmar Distl
A high quality of stallion semen is of particular importance for maximum reproductive efficiency. In the present study, we estimated the relationships among estimated breeding values (EBVs) of semen traits and EBVs for the paternal component of the pregnancy rate per estrus cycle (EBV-PAT) for 100 German Warmblood stallions using correlation and general linear model analyses. The most highly correlated sperm quality trait was total number of progressively motile sperm (r = 0.36). EBV-PAT was considered in three classes with stallions 1 SD below (<80), around (80-120), and above (>120) the population mean of 100...
February 2017: Theriogenology
https://www.readbyqxmd.com/read/28027263/pregnancy-and-the-plastic-surgery-resident
#14
Rebecca M Garza, Jane S Weston, Heather J Furnas
BACKGROUND: Combining pregnancy with plastic surgery residency has historically been difficult. Two decades ago, 36 percent of plastic surgery program directors surveyed actively discouraged pregnancy among residents, and 33 percent of women plastic surgeons suffered from infertility. Most alarmingly, 26 percent of plastic surgery trainees had had an elective abortion during residency. With increasing numbers of women training in plastic surgery, this historical lack of support for pregnancy deserves further attention...
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28024222/effects-of-prenatal-childbirth-education-for-partners-of-pregnant-women-on-paternal-postnatal-mental-health-and-couple-relationship-a-systematic-review
#15
REVIEW
Maiko Suto, Kenji Takehara, Yumina Yamane, Erika Ota
BACKGROUND: Partner education during pregnancy may be able to prevent postnatal mental health problems, and support expectant fathers in their transition to parenthood. The aim of this systematic review is to investigate the effects of prenatal childbirth education among partners of pregnant women, particularly regarding paternal postnatal mental health and couple relationship. METHODS: We searched Medline, CINAHL, EMBASE, PsycINFO, ERIC, and CENTRAL using terms such as "partners of pregnant women," "education," and "prenatal support...
December 20, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27884654/a-narrative-review-of-interventions-addressing-the-parental-fetal-relationship
#16
Nicole Borg Cunen, Julie Jomeen, Rita Borg Xuereb, Angela Poat
BACKGROUND: Expectant parents develop varying degrees of emotional affiliation with the unborn child. Interventions supporting this relationship may be beneficial given its link to maternal health behaviour during pregnancy, as well as the parental-infant bond after birth. AIM: To identify and describe the effects of programmes and strategies that have addressed the parental-fetal relationship. METHOD: English-language primary studies, published between 2005-2015, were identified and their methodological quality was assessed...
November 21, 2016: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/27855430/prospective-fathers-psychosocial-adaptation-and-involvement-in-the-last-trimester-of-pregnancy
#17
Karin Kuljanić, Tamara Martinac Dorčić, Ivana Ljubičić Bistrović, Alemka Brnčić-Fischer
BACKGROUND: Paternal involvement in pregnancy has been recognized to have an impact on new-born's outcomes and only recently got under the spot light of mental health perspective. The aim of this study was to test differences in paternal involvement in pregnancy, perceived stress and relationship quality regarding complications in pregnancy and pregnancy duration (gestational weeks) in the last trimester of pregnancy. The role of personality traits (neuroticism and extroversion), relationship quality satisfaction and perceived stress in prospective father's perception of pregnancy involvement were examined...
December 2016: Psychiatria Danubina
https://www.readbyqxmd.com/read/27780976/impact-of-parental-obesity-on-neonatal-markers-of-inflammation-and-immune-response
#18
M M Broadney, N Chahal, K A Michels, A C McLain, A Ghassabian, D A Lawrence, E H Yeung
BACKGROUND/OBJECTIVES: Maternal obesity may influence neonatal and childhood morbidities through increased inflammation and/or altered immune response. Less is known about paternal obesity. We hypothesized that excessive parental weight contributes to elevated inflammation and altered immunoglobulin (Ig) profiles in neonates. SUBJECTS/METHODS: In the Upstate KIDS Study maternal pre-pregnancy body mass index (BMI) was obtained from vital records and paternal BMI from maternal report...
January 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27751173/maternal-pre-pregnancy-body-mass-index-and-newborn-telomere-length
#19
Dries S Martens, Michelle Plusquin, Wilfried Gyselaers, Immaculata De Vivo, Tim S Nawrot
BACKGROUND: Newborn telomere length sets telomere length for later life. At birth, telomere length is highly variable among newborns and the environmental factors during in utero life for this observation remain largely unidentified. Obesity during pregnancy might reflect an adverse nutritional status affecting pregnancy and offspring outcomes, but the association of maternal pre-pregnancy body mass index (BMI) with newborn telomere length, as a mechanism of maternal obesity, on the next generation has not been addressed...
October 18, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27508762/-op-5d-06-hypertension-as-a-paternal-factor-influences-maternal-adaptation-to-pregnancy-and-is-associated-with-placental-insufficiency-and-fetal-growth-restriction
#20
G Barrientos, A Uceda, A Sgariglia, G Giardina, S M Blois, J E Toblli
OBJECTIVE: Severe forms of hypertensive disorders of pregnancy, like early-onset preeclampsia (PE), are often linked with abnormal placentation. Genetic factors contributed by the father may be important for placental development, and previous studies support the existence of a paternal component for PE and fetal growth restriction. Thus, the present study was conducted to evaluate the influence of arterial hypertension as a paternal factor on placental development and fetal growth in normal female rats...
September 2016: Journal of Hypertension
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