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https://www.readbyqxmd.com/read/29134464/phytochemical-properties-and-antioxidant-activities-of-extracts-from-wild-blueberries-and-lingonberries
#1
Paulina Dróżdż, Vaida Šėžienė, Krystyna Pyrzynska
Among Vaccinium species, blueberries (Vaccinium myrtillus L.) and lingonberries (Vaccinium vitis-idaea) are popular in the human diet. In this study, total phenolic, total flavonoid and total monomeric anthocyanin contents in the ethanol-water extracts of blueberry and lingonberry fruits grown wild in the forests in the central region of Poland were assayed. Antioxidant activities of the extracts from each plant were also evaluated for scavenging ability on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and reducing power by cupric reducing antioxidant capacity (CUPRAC) method...
November 14, 2017: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/29125471/carbon-dots-polyvinylpyrrolidone-hybrid-nanofibers-with-efficient-solid-state-photoluminescence-constructed-by-electrospinning-technique
#2
Yue Zhai, Xue Bai, Haining Cui, Jinyang Zhu, Wei Liu, Tianxiang Zhang, Biao Dong, Gencai Pan, Lin Xu, Shuang Zhang, Hongwei Song
Carbon dots (CDs) are the promising candidates for the application in the optoelectronic and biological areas due to their excellent photo-stability, unique photoluminescence, good biocompatibility, low toxicity and chemical inertness. However, the self-quenching of photoluminescence as they are dried into the solid-state dramatically limits their further applications. Therefore, realizing the efficient photoluminescence and large-scale production of CDs in the solid state is an urgent challenge. Herein, the solid-state hybrid nanofibers based on CDs and polyvinylpyrrolidone (PVP) are constructed through electrospinning process...
November 10, 2017: Nanotechnology
https://www.readbyqxmd.com/read/29123398/triclosan-resistance-reversion-by-encapsulation-in-chitosan-coated-nanocapsule-containing-%C3%AE-bisabolol-as-core-development-of-wound-dressing
#3
João Guilherme B De Marchi, Denise S Jornada, Fernanda K Silva, Ana L Freitas, Alexandre M Fuentefria, Adriana R Pohlmann, Silvia S Guterres
The use of nanoparticles may be particularly advantageous in treating bacterial infections due to their multiple simultaneous mechanisms of action. Nanoencapsulation is particularly useful for lipophilic drugs. In this scenario, triclosan is considered a good candidate due to its lipophilicity, broad-spectrum activity, and safety. In the present study, we have developed and characterized an antimicrobial suspension of triclosan and α-bisabolol against pathogenic strains that are resistant (Pseudomonas aeruginosa) and susceptible (Escherichia coli, Staphylococcus aureus, and Candida albicans) to triclosan...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29104301/effect-of-chyme-viscosity-and-nutrient-feedback-mechanism-on-gastric-emptying
#4
Thomas E Moxon, Philippe Nimmegeers, Dries Telen, Peter J Fryer, Jan Van Impe, Serafim Bakalis
A comprehensive mathematical model of the digestive processes in humans could allow for better design of functional foods which may play a role in stemming the prevalence of food related diseases around the world. This work presents a mathematical model for a nutrient based feedback mechanism controlling gastric emptying, which has been identified in vivo by numerous researchers. The model also takes into account the viscosity of nutrient meals upon gastric secretions and emptying. The results show that modelling the nutrient feedback mechanism as an on/off system, with an initial emptying rate dependent upon the secretion rate (which is a function of the gastric chyme viscosity) provides a good fit to the trends of emptying rate for liquid meals of low and high nutrient content with varying viscosity...
November 2, 2017: Chemical Engineering Science
https://www.readbyqxmd.com/read/29082683/-historical-evolution-and-change-of-differentiation-on-dried-ginger-fresh-ginger-and-baked-ginger
#5
Wen-Tao Fang, Zhi-Lai Zhan, Hua-Sheng Peng, Lu-Qi Huang
Ginger is commonly used as dietetic Chinese herbs, medicinal ginger mainly divided into dried ginger, fresh ginger and baked ginger. In this article, by sorting and studying literature of Chinese materia medica, textual criticism the historical evolution and change of differentiation on dried ginger, fresh ginger and baked ginger. Results indicate that, as the changes of the dynasty, dried ginger, fresh ginger and baked ginger gradually differentiation in producing area and processing method. Dried ginger beginning in Shennong Bencao Jing(Shennong's Classic of Materia Medica), Mingyi Bielu(Records of Famous Physicians) respectively included fresh ginger and dried ginger for the first time...
May 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29078123/adsorption-and-regeneration-of-expanded-graphite-modified-by-ctab-kbr-h3po4-for-marine-oil-pollution
#6
Congbin Xu, Chunlei Jiao, Ruihua Yao, Aijun Lin, Wentao Jiao
The cleaning-up of viscous oil spilled in ocean is a global challenge, especially in Bohai, due to its slow current movement and poor self-purification capacity. Frequent oil-spill accidents not only cause severe and long-term damages to marine ecosystems, but also lead to a great loss of valuable resources. To eliminate the environmental pollution of oil spills, an efficient and environment-friendly oil-recovery approach is necessary. In this study,(1)expanded graphite (EG) modified by CTAB-KBr/H3PO4 was synthesized via composite intercalation agents of CTAB-KBr and natural flake graphite, followed by the activation of phosphoric acid at low temperature...
October 24, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29072357/piper-regnellii-extract-biopolymer-based-microparticles-production-characterization-and-antifungal-activity
#7
Lara Zampar Serra Brambilla, Eliana Harue Endo, Diógenes Aparício Garcia Cortez, Marli Miriam de Souza Lima, Benedito Prado Dias Filho
AIMS: This study aims to improve characteristics of Piper regnellii extract to make it applicable in formulations to treat dermatophytosis, also known as ringworm. METHODS AND RESULTS: Microparticles were produced by spray-drying with gelatin, alginate and chitosan as encapsulating agents, characterized by scanning electron microscopy, encapsulation efficiency, thermal analyses, X-ray diffraction, and tested against Trichophyton rubrum by broth microdilution. Produced microparticles had a mean diameter less than 2 μm, an increase in stability and release of the extract and good results for encapsulation efficiency, being 85...
October 26, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29068609/dried-blood-spot-analysis-for-therapeutic-drug-monitoring-of-clozapine
#8
Lisanne M Geers, Dan Cohen, Laura M Wehkamp, Kai van Hateren, Remco A Koster, Olga Yu Fedorenko, Arkadyi V Semke, Nikolay Bokhan, Svetlana A Ivanova, Jos G W Kosterink, Anton J M Loonen, Daan J Touw
BACKGROUND: Schizophrenia is a psychiatric disorder that affects approximately 0.4%-1% of the population worldwide. Diagnosis of schizophrenia is based primarily on Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria. Clozapine is an antipsychotic drug that is mainly used in the treatment of schizophrenia patients who are refractory or intolerant to at least 2 other antipsychotics. Due to the high variability in pharmacokinetics of clozapine, therapeutic drug monitoring (TDM) is highly recommended for clozapine therapy...
October 24, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29054047/application-of-transglycosylated-stevia-and-hesperidin-as-drug-carriers-to-enhance-biopharmaceutical-properties-of-poorly-soluble-artemisinin
#9
Kumaran Letchmanan, Shou-Cang Shen, Wai Kiong Ng, Reginald B H Tan
Biopharmaceutical properties of poorly water-soluble antimalarial drug, Artemisinin (ART), were improved by formulating amorphous solid dispersions with transglycosylated food additives (Hsp-G and Stevia-G) via co-spray drying. Both the formulated ART/Hsp-G and ART/Stevia-G showed superior dissolution properties with a burst release of more than 95% of drug within 5 min, whereas untreated ART dissolved only 4% in 5min. The supersaturation solubility of the formulated ART was enhanced by 2-fold as compared with untreated counterpart...
October 7, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29053912/community-based-screening-of-hepatitis-c-with-a-one-step-rna-detection-algorithm-from-dried-blood-spots-analysis-of-key-populations-in-barcelona-spain
#10
V Saludes, C Folch, A Morales-Carmona, L Ferrer, L Fernández, R Muñoz, M Jiménez, E Loureiro, P Fernández-Dávila, E Bascuñana, J Casabona, E Martró
Alternative strategies are required to enhance the diagnosis of silent hepatitis C virus (HCV) infections in hard-to-reach key populations at risk. Among them, HCV prevalence and bio-behavioural data is scarce for HIV-negative men who have sex with men (MSM) and men and trans-women sex workers. We sought to describe and assess the potential benefits of a community-based one-step HCV screening and confirmatory strategy for these populations in Barcelona. The screening strategy based on a real-time RT-PCR assay for HCV-RNA detection in dried-blood spots (DBS) was validated and implemented in addition to an antibody point-of-care test in a community centre...
October 20, 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29053279/reduced-graphene-oxide-lii-composite-lithium-ion-battery-cathodes
#11
Sanghyeon Kim, Sung-Kon Kim, Pengcheng Sun, Nuri Oh, Paul V Braun
Li-iodine chemistry is of interest for electrochemical energy storage because it has been shown to provide both high power and high energy density. However, Li-iodine batteries are typically formed using Li metal and elemental iodine, which presents safety and fabrication challenges (e.g., the high vapor pressure of iodine). These disadvantages could be circumvented by using LiI as a starting cathode. Here, we present fabrication of a reduced graphene oxide (rGO)/LiI composite cathode, enabling for the first time the use of LiI as the Li-ion battery cathode...
October 20, 2017: Nano Letters
https://www.readbyqxmd.com/read/29051638/physical-characterization-of-whole-and-skim-dried-milk-powders
#12
Alessandro Pugliese, Giovanni Cabassi, Emma Chiavaro, Maria Paciulli, Eleonora Carini, Germano Mucchetti
The lack of updated knowledge about the physical properties of milk powders aimed us to evaluate selected physical properties (water activity, particle size, density, flowability, solubility and colour) of eleven skim and whole milk powders produced in Europe. These physical properties are crucial both for the management of milk powder during the final steps of the drying process, and for their use as food ingredients. In general, except for the values of water activity, the physical properties of skim and whole milk powders are very different...
October 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29051636/effects-of-different-carrier-materials-on-physicochemical-properties-of-microencapsulated-grape-skin-extract
#13
Ana M Kalušević, Steva M Lević, Bojan R Čalija, Jela R Milić, Vladimir B Pavlović, Branko M Bugarski, Viktor A Nedović
The goal of this study was to investigate the characteristics of grape skin extract (GSE) spray dried with different carriers: maltodextrin (MD), gum Arabic (GA) and skim milk powder (SMP). The grape skin extract was obtained from winery by-product of red grape variety Prokupac (Vitis vinifera L.). The morphology of the powders, their thermal, chemical and physical properties (water activity, bulk and tapped densities, solubility), as well as release studies in different pH conditions were analyzed. Total anthocyanin content and total phenolic content were determined by spectrophotometric methods...
October 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29048802/-liquid-chromatography-tandem-mass-spectrometry-method-for-determination-of-10-macrolide-antibiotics-in-pork-samples-using-on-line-solid-phase-extraction-purification
#14
Xiaoguang Zhang, Dong Liu, Hongran Liu, Qiang Li, Lili Li, Lixia Wang, Yan Zhang
A high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method based on-line solid phase extraction (SPE) purification was established to determine 10 macrolide antibiotics in pork samples. The samples were extracted with acetonitrile, and the extracts were dried with rotary evaporator at 40℃, then the analytes were dissolved with 2 mL phosphate buffer. The solutions were purified and concentrated by on-line SPE with HLB cartridges. The analytes were eluted with methanol, and then transferred to XBridge BEH C18 column, separated with the mobile phases of 10 mmol/L ammonium acetate aqueous solution and acetonitrile...
October 8, 2017: Se Pu, Chinese Journal of Chromatography
https://www.readbyqxmd.com/read/29048790/-simultaneous-determination-of-30-mycotoxins-in-different-feed-products-by-ultra-high-performance-liquid-chromatography-tandem-mass-spectrometry
#15
Zhichen Fan, Zheng Han, Wenbo Guo, Zhihui Zhao
A method for the simultaneous determination of 30 mycotoxins in different feed products was developed using a QuEChERS pretreatment procedure coupled with ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). The samples were extracted with 5 mL water and 5 mL acetonitrile containing 1% (v/v) formic acid. An aliquot of the supernatant was dried by nitrogen gas, re-dissolved by 1mL water containing 5 mmol/L ammonium acetate-acetonitrile (80:20, v/v), and analyzed by UHPLC-MS/MS...
June 8, 2017: Se Pu, Chinese Journal of Chromatography
https://www.readbyqxmd.com/read/29043216/proximate-phytochemical-and-in-vitro-antimicrobial-properties-of-dried-leaves-from-ocimum-gratissimum
#16
Justina Y Talabi, Solomon Akinremi Makanjuola
Ocimum gratissimum is a common plant in the tropics and has been used in food and medicine. Its usage in food and medicine could be attributed to its phtyochemical and antimicrobial properties. In this study we investigated the proximate, phytochemical, and antimicrobial attributes of air dried leaves of O. gratissimum. The aqueous extract was found to contain phtyochemicals with alkaloid and saponin present in appreciable amounts. The proximate analysis (crude protein and crude fibre content were 15.075% and 17...
September 2017: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/29042733/effect-of-melaleuca-alternifolia-mixed-with-tissue-conditioners-in-varying-doses-on-colonization-and-inhibition-of-candida-albicans-an-in-vitro-study
#17
Siva Kumar Vankadara, Rajendra Basavaraj Hallikerimath, Viraj Patil, Kishore Bhat, Mallikarjun Hanumantappa Doddamani
AIMS AND OBJECTIVES: The study was conducted to evaluate the Colonization & Inhibition of Candida albicans in selected commercially available denture lining materials material by mixing them with varying concentrations and doses of tea tree oil. MATERIALS AND METHODS: Five test discs of 10mm diameter and 1.5mm thickness were prepared using commercially available soft denture lining materials (Viscogel and GC-soft). Tea tree oil of varying concentrations (10%, 20%, 30%, and 40%) and doses (0...
July 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29040229/development-of-a-liquid-chromatography-tandem-mass-spectrometric-method-for-quantification-of-mycophenolic-acid-and-its-glucuronides-in-dried-blood-spot-samples
#18
Hiromasa Iboshi, Hiroaki Yamaguchi, Hiroyuki Suzuki, Masafumi Kikuchi, Masaki Tanaka, Shinya Takasaki, Akiko Takahashi, Masamitsu Maekawa, Miki Shimada, Yasushi Matsuda, Yoshinori Okada, Nariyasu Mano
BACKGROUND: Personalized immunosuppressive therapy, including accurate drug dosing based on the drug blood level, leads to better clinical outcomes, specifically regarding avoidance of drug-induced adverse effects and maintenance of efficacy. Mycophenolic acid (MPA) is used as an immunosuppressant in transplantation of various solid organs. The aim of this study was to develop a method for quantification of MPA and its metabolites, mycophenolic acid 7-O-glucuronide (MPAG) and mycophenolic acid acyl glucuronide, in dried blood spot (DBS) samples, using liquid chromatography/electrospray ionization/tandem mass spectrometry...
December 2017: Therapeutic Drug Monitoring
https://www.readbyqxmd.com/read/29036589/simultaneous-determination-of-11-high-polarity-components-from-fructus-corni-a-quantitative-lc-ms-ms-method-for-improved-quality-control
#19
Liling Wang, Hui Chen, Yuhong Jiang, Zhihui Liu, Qiong Wang, Xiao Zheng
Fructus Corni, the dried ripe sarcocarp of Cornus officinalis Sieb.et Zucc (Cornaceae), is widely used in traditional medicine. Pharmacological studies to date have attributed many biological effects to the high-polarity components. However, current quality control methods focus on only several iridoid glycoside components, and, of note, there is no comprehensive method available to simultaneously quantify the high-polarity components in Fructus Corni. Here, a simple, sensitive and robust liquid chromatography-electrospray ionization-tandem mass spectrometry method was developed to simultaneously determine 11 high-polarity constituents (5-hydroxymethyl-2-furfural, gallic acid, sweroside, cornin, loganin, morroniside, 7α-O-methylmorroniside, 7β-O-methylmorroniside, 7α-O-ethylmorroniside and 7β-O-ethylmorroniside, cornuside) of Fructus Corni...
September 28, 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/29035057/freeze-dried-sulfur-graphene-oxide-carbon-nanotube-nanocomposite-for-high-sulfur-loading-lithium-sulfur-cells
#20
Yoon Hwa, Hyeon Kook Seo, Jong-Min Yuk, Elton J Cairns
The ambient-temperature rechargeable lithium/sulfur (Li/S) cell is a strong candidate for the beyond lithium ion cell since significant progress on developing advanced sulfur electrodes with high sulfur loading has been made. Here we report on a new sulfur electrode active material consisting of a cetyltrimethylammonium bromide-modified sulfur-graphene oxide-carbon nanotube (S-GO-CTA-CNT) nanocomposite prepared by freeze-drying. We show the real-time formation of nanocrystalline lithium sulfide (Li2S) at the interface between the S-GO-CTA-CNT nanocomposite and the liquid electrolyte by in situ TEM observation of the reaction...
October 23, 2017: Nano Letters
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