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https://www.readbyqxmd.com/read/28319384/eugenol-nanoemulsion-stabilized-with-zein-and-sodium-caseinate-by-self-assembly
#1
Lei Wang, Yue Zhang
Eugenol-loaded nanoemulsion by zein and sodium caseinate (NaCas) was prepared without using specific equipment or organic solvents. The deprotonated eugenol in hot alkaline was added into NaCas/zein mixtures with different mass ratios at pH 11.5, and then neutralized to pH 7.0. The nanoemulsions showed well-defined diameter (around 109-139 nm) and negative surface potential (-28.5~ -35.8 mv). The entrapment efficiency (EE) of 1% v/v eugenol reached 84.24% by 2% m/v NaCas/zein at a mass ratio of 1:1. This formulation also showed the narrowest size distribution, extraordinary stability during ambient storage (22 oC) up to 30 days, and retained good re-dispersiblity after spray- or freeze- drying...
March 20, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28302120/responsiveness-of-cats-felidae-to-silver-vine-actinidia-polygama-tatarian-honeysuckle-lonicera-tatarica-valerian-valeriana-officinalis-and-catnip-nepeta-cataria
#2
Sebastiaan Bol, Jana Caspers, Lauren Buckingham, Gail Denise Anderson-Shelton, Carrie Ridgway, C A Tony Buffington, Stefan Schulz, Evelien M Bunnik
BACKGROUND: Olfactory stimulation is an often overlooked method of environmental enrichment for cats in captivity. The best known example of olfactory enrichment is the use of catnip, a plant that can cause an apparently euphoric reaction in domestic cats and most of the Pantherinae. It has long been known that some domestic cats and most tigers do not respond to catnip. Although many anecdotes exist of other plants with similar effects, data are lacking about the number of cats that respond to these plants, and if cats that do not respond to catnip respond to any of them...
March 16, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28301177/trust-trolleys-and-social-dilemmas-a-replication-study
#3
Dries H Bostyn, Arne Roets
The present manuscript addresses how perceived trustworthiness of cooperative partners in a social dilemma context is influenced by the moral judgments those partners make on Trolley-type moral dilemmas; an issue recently investigated by Everett, Pizarro, and Crockett (2016). The present research comprises 2 studies that were conducted independently, simultaneously with, and incognizant of the Everett studies. Whereas the present studies aimed at investigating the same research hypothesis, a different and more elaborate methodology was used, as such providing a conceptual replication opportunity and extension to the Everett et al...
March 16, 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/28300144/fast-detection-of-tobacco-mosaic-virus-infected-tobacco-using-laser-induced-breakdown-spectroscopy
#4
Jiyu Peng, Kunlin Song, Hongyan Zhu, Wenwen Kong, Fei Liu, Tingting Shen, Yong He
Tobacco mosaic virus (TMV) is one of the most devastating viruses to crops, which can cause severe production loss and affect the quality of products. In this study, we have proposed a novel approach to discriminate TMV-infected tobacco based on laser-induced breakdown spectroscopy (LIBS). Two different kinds of tobacco samples (fresh leaves and dried leaf pellets) were collected for spectral acquisition, and partial least squared discrimination analysis (PLS-DA) was used to establish classification models based on full spectrum and observed emission lines...
March 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28294988/ellagitannins-of-davidia-involucrata-i-structure-of-davicratinic-acid-a-and-effects-of-davidia-tannins-on-drug-resistant-bacteria-and-human-oral-squamous-cell-carcinomas
#5
Yuuki Shimozu, Yuriko Kimura, Akari Esumi, Hiroe Aoyama, Teruo Kuroda, Hiroshi Sakagami, Tsutomu Hatano
We isolated a new ellagitannin, davicratinic acid A (5), together with four known ellagitannins, davidiin (1), granatin A (2), pedunculagin (3), and 3-O-galloylgranatin A (4), from an aqueous acetone extract of dried Davidia involucrata leaves. The known ellagitannins were identified based on spectroscopic data. The structure of davicratinic acid A (5), a monomeric ellagitannin possessing a unique, skew-boat glucopyranose core, was established based on spectroscopic data. Additionally, we examined the effects of several tannins with good yields from this plant on drug-resistant bacteria and human oral squamous cell carcinomas, and found that davidiin (1) exhibited the most potent antibacterial and antitumor properties among the tannins examined...
March 15, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28293942/a-new-dendritic-polydiacetylene-sensor-with-good-reversible-thermochromic-ability-in-aqueous-solution-and-solid-film
#6
Wenjie Dong, Guanhua Lin, Haifei Wang, Wensheng Lu
Thermal responsive polydiacetylene derived from PAMAM dendrimer (PDA-G0) was synthesized. Unlike the ethylenediamine substituted PDA (PDA-NH2) solution, the prepared PDA-G0 vesicle solution showed reversible thermochromism property when temperature varied from 20 oC to 90 oC, which is due to formation of internal hydrogen-bond in amide groups. Furthermore, PDA-G0/PMMA film with excellent stability was obtained by a mixed-drying method, which could be stored for a long time without denaturation. After polymerization by UV irradiation, it displayed much better reversible thermochromic ability and the responded temperature range became wider, from 20 oC to110 oC...
March 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28291206/-potential-for-use-of-hydroxypropyl-guar-in-tear-substitute-therapy
#7
V V Brzhesky, S Yu Golubev
Of the large number of polymers used in artificial tear formulations, natural polysaccharides - hydroxypropyl guar, sodium hyaluronate, chondroitin sulfate, dextran, etc., are gaining more and more popularity. Hydroxypropyl guar stands out through its ability to form a long-lasting structured matrix adhered to the damaged ocular surface and ensuring good wettability of the latter and regeneration of epithelial cells. At that, the viscosity of hydroxypropyl guar increases with increasing tear pH (which, in turn, correlates with the severity of xerosis) and further prolongs the moisturizing effect...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28287572/rapid-mix-preparation-of-bioinspired-nanoscale-hydroxyapatite-for-biomedical-applications
#8
Caroline J Wilcock, Piergiorgio Gentile, Paul V Hatton, Cheryl A Miller
Hydroxyapatite (HA) has been widely used as a medical ceramic due to its good biocompatibility and osteoconductivity. Recently there has been interest regarding the use of bioinspired nanoscale hydroxyapatite (nHA). However, biological apatite is known to be calcium-deficient and carbonate-substituted with a nanoscale platelet-like morphology. Bioinspired nHA has the potential to stimulate optimal bone tissue regeneration due to its similarity to bone and tooth enamel mineral. Many of the methods currently used to fabricate nHA both in the laboratory and commercially, involve lengthy processes and complex equipment...
February 23, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28285981/novel-budesonide-particles-for-dry-powder-inhalation-dpi-prepared-using-a-microfluidic-reactor-coupled-with-ultrasonic-spray-freeze-drying
#9
Denis Saboti, Uroš Maver, Hak-Kim Chan, Odon Planinšek
Budesonide is a potent active pharmaceutical ingredient, often administered using respiratory devices such as metered dose inhalers (MDI), nebulizers and dry powder inhalers (DPI). Inhalable drug particles are conventionally produced by crystallization followed by milling. This approach tends to generate partially amorphous materials that require post-processing to improve the formulations' stability. Other methods involve homogenization or precipitation and often require the use of stabilizers, mostly surfactants...
March 9, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28282259/study-on-the-pulmonary-delivery-system-of-apigenin-loaded-albumin-nanocarriers-with-antioxidant-activity
#10
Zsófia Edit Pápay, Annamária Kósa, Béla Böddi, Zahra Merchant, Imran Y Saleem, Mohammed Gulrez Zariwala, Imre Klebovich, Satyanarayana Somavarapu, István Antal
BACKGROUND: Respiratory diseases are mainly derived from acute and chronic inflammation of the alveoli and bronchi. The pathophysiological mechanisms of pulmonary inflammation mainly arise from oxidative damage that could ultimately lead to acute lung injury. Apigenin (Api) is a natural polyphenol with prominent antioxidant and anti-inflammatory properties in the lung. Inhalable formulations that consist of nanoparticles (NPs) have several advantages over other administration routes, and therefore, this study investigated the application of apigenin-loaded bovine serum albumin nanoparticles (BSA-Api-NPs) for pulmonary delivery...
March 10, 2017: Journal of Aerosol Medicine and Pulmonary Drug Delivery
https://www.readbyqxmd.com/read/28274446/the-effect-of-pigment-matrix-temperature-and-amount-of-carrier-on-the-yield-and-final-color-properties-of-spray-dried-purple-corn-zea-mays-l-cob-anthocyanin-powders
#11
Fei Lao, M Monica Giusti
Spray drying is an economic technique to produce anthocyanin-based colorants. High pigments yields with minimum color degradation are desirable to maximize quality and profits. This study evaluated the impacts of purple corncob (PCC) anthocyanin extraction matrices (hot water, 40% ethanol, C18 purified), drying inlet temperature (130, 150, 170°C) and amount of carrier (2%, 5%, 10% maltodextrin) on the yields and quality of PCC anthocyanin powders. Monomeric and polymeric anthocyanins, color properties (CIELch, haze), and pigments composition before and after spray drying were determined...
July 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28274428/addition-of-chia-seed-mucilage-for-reduction-of-fat-content-in-bread-and-cakes
#12
Sibele Santos Fernandes, Myriam de Las Mercedes Salas-Mellado
In this study, breads and chocolate cakes were prepared with different levels of chia mucilage dried at 50°C or lyophilized as fat, resulting in healthier products. Results indicated that breads and chocolate cakes made with chia mucilage can replace up to 50% of fat without affecting the technological and physical characteristics. The replacement of 75% of fat, for both types of mucilage, had a significant reduction in fat content of 56.6% in breads and 51.6% in cakes, producing a slight decrease in the technological characteristics of the products...
July 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28267507/lanthanide-ions-induced-formation-of-hierarchical-and-transparent-polysaccharide-hybrid-films
#13
Shunli Liu, Kewen Li, Fang Yao, Liqun Xu, Guodong Fu
Nacre-like hybrid films based on N-succinyl chitosan (NSC), sodium alginate (SA) and lanthanide ions were fabricated via coordination interactions. In this work, the binary building blocks (NSC and SA) were self-assembled into aligned hydrogel films by coordination with lanthanide ions, and hierarchical NSC-SA hybrid films were obtained upon drying. Two species of lanthanide ions (Gd(3+) and Yb(3+)) were used to fabricate the hierarchical NSC-SA hybrid films. The as-prepared NSC-SA hybrid films exhibit high tensile strength and stability...
May 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28267502/flexible-starch-polyurethane-films-physiochemical-characteristics-and-hydrophobicity
#14
N L Tai, Raju Adhikari, Robert Shanks, Benu Adhikari
Starch-polyurethane (PU) composite films with improved mechanical and hydrophobic properties were developed in this work. A simple and effective microwave-aided starch gelatinisation instrument was used to prepare glycerol plasticized high amylose starch (HAGS) material. Polyethylene glycol-isocyanate (PEG-iso) linker was prepared by reacting PEG 1000 with hexamethylene diisocyanate (HMDI). PEG-iso linker was then grafted into HAGS forming three dimensional urethane networks (PEG-PU). HAGS-PEG-PU composite blends were prepared and dried at ambient temperature to obtain HAGS-PEG-PU films...
May 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28267486/renewable-hybrid-nanocatalyst-from-magnetite-and-cellulose-for-treatment-of-textile-effluents
#15
Ana Carolina Cunha Arantes, Crislaine das Graças Almeida, Ligiane Carolina Leite Dauzacker, Maria Lucia Bianchi, Delilah F Wood, Tina G Williams, William J Orts, Gustavo Henrique Denzin Tonoli
A hybrid catalyst was prepared using cellulose nanofibrils and magnetite to degrade organic compounds. Cellulose nanofibrils were isolated by mechanical defibrillation producing a suspension used as a matrix for magnetite particles. The solution of nanofibrils and magnetite was dried and milled resulting in a catalyst with a 1:1 ratio of cellulose and magnetite that was chemically and physically characterized using light, scanning electron and transmission electron microscopies, specific surface area analysis, vibrating sample magnetometry, thermogravimetric analysis, Fourier transform infrared spectroscopy, X-ray diffraction, catalytic potential and degradation kinetics...
May 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28266292/two-and-a-half-hours-of-cardiopulmonary-resuscitation-in-a-deceased-brain-dead-donor-before-liver-transplantation-a-good-idea-to-accept
#16
Dieter P Hoyer, Gernot M Kaiser, Andreas Paul, Nikolaos Machairas, Ernesto P Molmenti, Georgios C Sotiropoulos
The sequelae of cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) in organ donors potentially results in ischemic organ injury and graft dysfunction after transplantation. Thresholds of resuscitation times in brain dead liver donors have not been established so far. We report the case of a brain dead liver donor who experienced 2.5 hours of CPR whose liver was successfully transplanted. A 75-year-old male experienced CA and was treated by CPR with streptokinase application for 2.5 hours until stabilization of cardiac function...
January 2017: Chirurgia
https://www.readbyqxmd.com/read/28265366/micronutrient-composition-and-acceptability-of-moringa-oleifera-leaf-fortified-dishes-by-children-in-ada-east-district-ghana
#17
Mary Glover-Amengor, Richmond Aryeetey, Edwin Afari, Alexander Nyarko
Moringa oleifera (M. oleifera), a green leafy vegetable, is a good source of minerals and vitamins which could be consumed as part of diet to improve human health and well-being. Drying M. oleifera leaves could make it readily available for use as a food fortificant. The objectives of the study were to determine micromineral and β -carotene content of dried M. oleifera leaves, and leaf-incorporated local dishes, and also assess school children's (4-12 yr) acceptability of dried M. oleifera leaf-incorporated local dishes and feasibility of introducing dried leaves into a school lunch menu...
March 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28259253/establishment-of-one-step-approach-to-detoxification-of-hypertoxic-aconite-based-on-the-evaluation-of-alkaloids-contents-and-quality
#18
Ding-Kun Zhang, Xue Han, Peng Tan, Rui-Yu Li, Ming Niu, Cong-En Zhang, Jia-Bo Wang, Ming Yang, Xiao-He Xiao
Aconite is a valuable drug and also a toxic material, which can be used only after detoxification processing. Although traditional processing methods can achieve detoxification effect as desired, there are some obvious drawbacks, including a significant loss of alkaloids and poor quality consistency. It is thus necessary to develop a new detoxification approach. In the present study, we designed a novel one-step detoxification approach by quickly drying fresh-cut aconite particles. In order to evaluate the technical advantages, the contents of mesaconitine, aconitine, hypaconitine, benzoylmesaconine, benzoylaconine, benzoylhypaconine, neoline, fuziline, songorine, and talatisamine were determined using HPLC and UHPLC/Q-TOF-MS...
January 2017: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/28250655/pharmacognostic-specifications-and-lawsone-content-of-lawsonia-inermis-leaves
#19
Rawiwan Charoensup, Thidarat Duangyod, Chanida Palanuvej, Nijsiri Ruangrungsi
BACKGROUND: Lawsonia inermis L. has been used as a traditional or folk medicine for the treatment of a wide range of skin infectious diseases. OBJECTIVE: The objective of this study was to determine the pharmacognostic specifications and lawsone contents of L. inermis leaves. MATERIALS AND METHODS: The pharmacognostic specifications of L. inermis leaves from 12 sources were evaluated according to the WHO guideline of quality control method for medicinal plant materials...
January 2017: Pharmacognosy Research
https://www.readbyqxmd.com/read/28248111/inclusion-complexation-of-etodolac-with-hydroxypropyl-beta-cyclodextrin-and-auxiliary-agents-formulation-characterization-and-molecular-modeling-studies
#20
Atul P Sherje, Vaidehi Kulkarni, Manikanta Murahari, Usha Y Nayak, Pritesh Bhat, Vasanti Suvarna, Bhushan Dravyakar
The present investigation was aimed to prepare inclusion complexes of a therapeutically important nonsteroidal anti-inflammatory drug, etodolac (ETD) with hydroxypropyl-beta-cyclodextrin (HP-β-CD) and to study the effect of l-arginine (l-Arg) as an auxiliary agent on the complexation efficiency of HP-β-CD to improve aqueous solubility and the dissolution property of ETD. The binary and ternary complexes were prepared by physical mixing, coevaporation, and spray drying methods. The complexes were characterized using differential scanning colorimetry (DSC), Fourier transform-infrared spectroscopy (FT-IR), and powder X-ray diffraction (PXRD) studies...
March 1, 2017: Molecular Pharmaceutics
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