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https://www.readbyqxmd.com/read/28636165/a-feasibility-and-safety-study-of-intracoronary-hemodilution-during-primary-coronary-angioplasty-in-order-to-reduce-reperfusion-injury-in-myocardial-infarction
#1
Michael McGarvey, Omar Ali, M Bilal Iqbal, Charles Ilsley, Joyce Wong, Carlo Di Mario, Simon Redwood, Tiffany Patterson, Dudley J Pennell, Paula Rogers, Miles Dalby
OBJECTIVES: We designed a pilot study to evaluate safety and feasibility of an inexpensive and simple approach to intracoronary hemodilution during primary angioplasty (PPCI) to reduce reperfusion injury. INTRODUCTION: Early revascularization in acute myocardial infarction decreases infarct size and improves outcomes. However, abrupt restoration of coronary flow results in myocardial reperfusion injury and increased final infarct size. Dilution of coronary blood during revascularization may help reduce this damage...
June 21, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28608423/a-toolchain-for-the-automatic-generation-of-computer-codes-for-correlated-wavefunction-calculations
#2
Martin Krupička, Kantharuban Sivalingam, Lee Huntington, Alexander A Auer, Frank Neese
In this work, the automated generator environment for ORCA (ORCA-AGE) is described. It is a powerful toolchain for the automatic implementation of wavefunction-based quantum chemical methods. ORCA-AGE consists of three main modules: (1) generation of "raw" equations from a second quantized Ansatz for the wavefunction, (2) factorization and optimization of equations, and (3) generation of actual computer code. We generate code for the ORCA package, making use of the powerful functionality for wavefunction-based correlation calculations that is already present in the code...
June 13, 2017: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/28606065/neurocognitive-function-in-hiv-infected-persons-with-asymptomatic-cryptococcal-antigenemia-a-comparison-of-three-prospective-cohorts
#3
Martha P Montgomery, Noeline Nakasujja, Bozena M Morawski, Radha Rajasingham, Joshua Rhein, Elizabeth Nalintya, Darlisha A Williams, Kathy Huppler Hullsiek, Agnes Kiragga, Melissa A Rolfes, Renee Donahue Carlson, Nathan C Bahr, Kate E Birkenkamp, Yukari C Manabe, Paul R Bohjanen, Jonathan E Kaplan, Andrew Kambugu, David B Meya, David R Boulware
BACKGROUND: HIV-infected persons with detectable cryptococcal antigen (CrAg) in blood have increased morbidity and mortality compared with HIV-infected persons who are CrAg-negative. This study examined neurocognitive function among persons with asymptomatic cryptococcal antigenemia. METHODS: Participants from three prospective HIV cohorts underwent neurocognitive testing at the time of antiretroviral therapy (ART) initiation. Cohorts included persons with cryptococcal meningitis (N = 90), asymptomatic CrAg + (N = 87), and HIV-infected persons without central nervous system infection (N = 125)...
June 12, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28564647/64th-orca-congress-july-5-8-2017-oslo-norway-abstracts
#4
(no author information available yet)
No abstract text is available yet for this article.
June 1, 2017: Caries Research
https://www.readbyqxmd.com/read/28554115/blubber-depth-distribution-and-bioaccumulation-of-pcbs-and-organochlorine-pesticides-in-arctic-invading-killer-whales
#5
Sara Pedro, Conor Boba, Rune Dietz, Christian Sonne, Aqqalu Rosing-Asvid, Martin Hansen, Anthony Provatas, Melissa A McKinney
Sightings of killer whales (Orcinus orca) in Greenland have increased in recent years, coincident with sea ice loss. These killer whales are likely from fish-feeding North Atlantic populations, but may have access to marine mammal prey in Greenlandic waters, which could lead to increased exposures to biomagnifying contaminants. Most studies on polychlorinated biphenyl (PCB) and organochlorine (OC) contaminants in killer whales have used biopsies which may not be representative of contaminant concentrations through the entire blubber depth...
May 26, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28487524/vertebral-bone-microarchitecture-and-osteocyte-characteristics-of-three-toothed-whale-species-with-varying-diving-behaviour
#6
Tim Rolvien, Michael Hahn, Ursula Siebert, Klaus Püschel, Hans-Joachim Wilke, Björn Busse, Michael Amling, Ralf Oheim
Although vertebral bone microarchitecture has been studied in various tetrapods, limited quantitative data are available on the structural and compositional changes of vertebrae in marine mammals. Whales exhibit exceptional swimming and diving behaviour, and they may not be immune to diving-associated bone pathologies. Lumbar vertebral bodies were analysed in three toothed whale species: the sperm whale (Physeter macrocephalus), orca (Orcinus orca) and harbour porpoise (Phocoena phocoena). The bone volume fraction (BV/TV) did not scale with body size, although the trabeculae were thicker, fewer in number and further apart in larger whale species than in the other two species...
May 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28464669/killer-whale-orcinus-orca-behavioral-audiograms
#7
Brian K Branstetter, Judy St Leger, Doug Acton, John Stewart, Dorian Houser, James J Finneran, Keith Jenkins
Killer whales (Orcinus orca) are one of the most cosmopolitan marine mammal species with potential widespread exposure to anthropogenic noise impacts. Previous audiometric data on this species were from two adult females [Szymanski, Bain, Kiehl, Pennington, Wong, and Henry (1999). J. Acoust. Soc. Am. 108, 1322-1326] and one sub-adult male [Hall and Johnson (1972). J. Acoust. Soc. Am. 51, 515-517] with apparent high-frequency hearing loss. All three killer whales had best sensitivity between 15 and 20 kHz, with thresholds lower than any odontocete tested to date, suggesting this species might be particularly sensitive to acoustic disturbance...
April 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28429612/a-unique-database-for-gathering-data-from-a-mobile-app-and-medical-prescription-software-a-useful-data-source-to-collect-and-analyse-patient-reported-outcomes-of-depression-and-anxiety-symptoms
#8
Yoshinori Watanabe, Yoko Hirano, Yuko Asami, Maki Okada, Kazuya Fujita
A unique database named 'AN-SAPO' was developed by Iwato Corp. and Japan Brain Corp. in collaboration with the psychiatric clinics run by Himorogi Group in Japan. The AN-SAPO database includes patients' depression/anxiety score data from a mobile app named AN-SAPO and medical records from medical prescription software named 'ORCA'. On the mobile app, depression/anxiety severity can be evaluated by answering 20 brief questions and the scores are transferred to the AN-SAPO database together with the patients' medical records on ORCA...
April 21, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28273531/a-rapid-analytical-method-to-quantify-complex-organohalogen-contaminant-mixtures-in-large-samples-of-high-lipid-mammalian-tissues
#9
Jean-Pierre Desforges, Igor Eulaers, Luke Periard, Christian Sonne, Rune Dietz, Robert J Letcher
In vitro investigations of the health impact of individual chemical compounds have traditionally been used in risk assessments. However, humans and wildlife are exposed to a plethora of potentially harmful chemicals, including organohalogen contaminants (OHCs). An alternative exposure approach to individual or simple mixtures of synthetic OHCs is to isolate the complex mixture present in free-ranging wildlife, often non-destructively sampled from lipid rich adipose. High concentration stock volumes required for in vitro investigations do, however, pose a great analytical challenge to extract sufficient amounts of complex OHC cocktails...
June 2017: Chemosphere
https://www.readbyqxmd.com/read/28266120/prevention-and-control-of-dental-caries-and-periodontal-diseases-at-individual-and-population-level-consensus-report-of-group-3-of-joint-efp-orca-workshop-on-the-boundaries-between-caries-and-periodontal-diseases
#10
Søren Jepsen, Juan Blanco, Wolfgang Buchalla, Joana C Carvalho, Thomas Dietrich, Christof Dörfer, Kenneth A Eaton, Elena Figuero, Jo E Frencken, Filippo Graziani, Susan M Higham, Thomas Kocher, Marisa Maltz, Alberto Ortiz-Vigon, Julian Schmoeckel, Anton Sculean, Livia M A Tenuta, Monique H van der Veen, Vita Machiulskiene
BACKGROUND: The non-communicable diseases dental caries and periodontal diseases pose an enormous burden on mankind. The dental biofilm is a major biological determinant common to the development of both diseases, and they share common risk factors and social determinants, important for their prevention and control. The remit of this working group was to review the current state of knowledge on epidemiology, socio-behavioural aspects as well as plaque control with regard to dental caries and periodontal diseases...
March 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28266115/socio-behavioural-aspects-in-the-prevention-and-control-of-dental-caries-and-periodontal-diseases-at-an-individual-and-population-level
#11
Sonja Sälzer, Mohammad Alkilzy, Dagmar E Slot, Christof E Dörfer, Julian Schmoeckel, Christian H Splieth
AIM: Aim was to systematically review behavioural aspects in the prevention and control of dental caries and periodontal diseases at individual and population level. MATERIAL & METHODS: With regard to caries, MEDLINE/PubMed was searched on three subheadings focusing on early childhood, proximal and root caries. For periodontal diseases, a meta-review on systematic reviews was performed; thus, the search strategy included specific interventions to change behaviour in order to perform a meta-review on systematic reviews...
March 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28266114/interaction-of-lifestyle-behaviour-or-systemic-diseases-with-dental-caries-and-periodontal-diseases-consensus-report-of-group-2-of-the-joint-efp-orca-workshop-on-the-boundaries-between-caries-and-periodontal-diseases
#12
Iain L C Chapple, Philippe Bouchard, Maria Grazia Cagetti, Guglielmo Campus, Maria-Clotilde Carra, Fabio Cocco, Luigi Nibali, Philippe Hujoel, Marja L Laine, Peter Lingstrom, David J Manton, Eduardo Montero, Nigel Pitts, Hélène Rangé, Nadine Schlueter, Wim Teughels, Svante Twetman, Cor Van Loveren, Fridus Van der Weijden, Alexandre R Vieira, Andreas G Schulte
Periodontal diseases and dental caries are the most common diseases of humans and the main cause of tooth loss. Both diseases can lead to nutritional compromise and negative impacts upon self-esteem and quality of life. As complex chronic diseases, they share common risk factors, such as a requirement for a pathogenic plaque biofilm, yet they exhibit distinct pathophysiologies. Multiple exposures contribute to their causal pathways, and susceptibility involves risk factors that are inherited (e.g. genetic variants), and those that are acquired (e...
March 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28266112/dental-caries-and-periodontal-diseases-in-the-ageing-population-call-to-action-to-protect-and-enhance-oral-health-and-well-being-as-an-essential-component-of-healthy-ageing-consensus-report-of-group-4-of-the-joint-efp-orca-workshop-on-the-boundaries-between
#13
Maurizio S Tonetti, Peter Bottenberg, Georg Conrads, Peter Eickholz, Peter Heasman, Marie-Charlotte Huysmans, Rodrigo López, Phoebus Madianos, Frauke Müller, Ian Needleman, Bente Nyvad, Philip M Preshaw, Iain Pretty, Stefan Renvert, Falk Schwendicke, Leonardo Trombelli, Gert-Jan van der Putten, Jacques Vanobbergen, Nicola West, Alix Young, Sebastian Paris
BACKGROUND: Over the last two decades, progress in prevention and treatment of caries and periodontal diseases has been translated to better oral health and improved tooth retention in the adult population. The ageing population and the increasing expectations of good oral health-related quality of life in older age pose formidable challenges to clinical care and healthcare systems. AIMS: The objective of this workshop was to critically review scientific evidence and develop specific recommendations to: (i) prevent tooth loss and retain oral function through prevention and treatment of caries and periodontal diseases later in life and (ii) increase awareness of the health benefits of oral health as an essential component of healthy ageing...
March 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28266109/role-of-microbial-biofilms-in-the-maintenance-of-oral-health-and-in-the-development-of-dental-caries-and-periodontal-diseases-consensus-report-of-group-1-of-the-joint-efp-orca-workshop-on-the-boundaries-between-caries-and-periodontal-disease
#14
Mariano Sanz, David Beighton, Michael A Curtis, Jaime A Cury, Irene Dige, Henrik Dommisch, Roger Ellwood, Rodrigo Giacaman, David Herrera, Mark C Herzberg, Eija Könönen, Philip D Marsh, Joerg Meyle, Alex Mira, Ana Molina, Andrea Mombelli, Marc Quirynen, Eric C Reynolds, Lior Shapira, Egija Zaura
BACKGROUND AND AIMS: The scope of this working group was to review (1) ecological interactions at the dental biofilm in health and disease, (2) the role of microbial communities in the pathogenesis of periodontitis and caries, and (3) the innate host response in caries and periodontal diseases. RESULTS AND CONCLUSIONS: A health-associated biofilm includes genera such as Neisseria, Streptococcus, Actinomyces, Veillonella and Granulicatella. Microorganisms associated with both caries and periodontal diseases are metabolically highly specialized and organized as multispecies microbial biofilms...
March 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28239473/fine-scale-foraging-movements-by-fish-eating-killer-whales-orcinus-orca-relate-to-the-vertical-distributions-and-escape-responses-of-salmonid-prey-oncorhynchus-spp
#15
Brianna M Wright, John K B Ford, Graeme M Ellis, Volker B Deecke, Ari Daniel Shapiro, Brian C Battaile, Andrew W Trites
BACKGROUND: We sought to quantitatively describe the fine-scale foraging behavior of northern resident killer whales (Orcinus orca), a population of fish-eating killer whales that feeds almost exclusively on Pacific salmon (Oncorhynchus spp.). To reconstruct the underwater movements of these specialist predators, we deployed 34 biologging Dtags on 32 individuals and collected high-resolution, three-dimensional accelerometry and acoustic data. We used the resulting dive paths to compare killer whale foraging behavior to the distributions of different salmonid prey species...
2017: Movement Ecology
https://www.readbyqxmd.com/read/28218526/dinuclear-metallacycles-with-single-m-x-m-bridges-x-cl-br-m-fe-ii-co-ii-ni-ii-cu-ii-zn-ii-cd-ii-strong-antiferromagnetic-superexchange-interactions
#16
Daniel L Reger, Andrea E Pascui, Elizabeth A Foley, Mark D Smith, Julia Jezierska, Agnieszka Wojciechowska, Sebastian A Stoian, Andrew Ozarowski
A series of monochloride-bridged, dinuclear metallacycles of the general formula [M2(μ-Cl)(μ-L)2](ClO4)3 have been prepared using the third-generation, ditopic bis(pyrazolyl)methane ligands L = m-bis[bis(1-pyrazolyl)methyl]benzene (Lm), M = Cu(II), Zn(II), and L = m-bis[bis(3,5-dimethyl-1-pyrazolyl)methyl]benzene (Lm*), M = Fe(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II). These complexes were synthesized from the direct reactions of M(ClO4)2·6H2O, MCl2, and the ligand, Lm or Lm*, in the appropriate stoichiometric amounts...
February 20, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28187472/-epi-bowman-keratectomy-clinical-evaluation-of-a-new-method-of-surface-ablation
#17
S Taneri, S Kießler, A Rost, T Schultz, M Elling, B Dick
Purpose A new device for epithelial abrasion before excimer laser surface ablation or corneal cross-linking (CXL) has recently been introduced (Epi-Clear™, Orca Surgical, Kiryat-Shmona, Israel). We have reviewed the literature on the clinical results, potential benefits and drawbacks of this instrument, compared to other methods of epithelial removal. Method Literature search for "Epi-Bowman Keratectomy", "Epi-clear", and "Epikeratome" yielded 1 peer-review publication, 1 non-peer-review publication, 18 posters and presentations at international conferences (European Society of Cataract and Refractive Surgeons [ESCRS] and American Society of Cataract and Refractive Surgery [ASCRS]) on the use of the Epi-Clear™ device before surface ablation, 2 posters on the use of Epi-Clear before corneal crosslinking and 1 presentation on the experimental use of Epi-Clear for removal of a pterygium...
February 10, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28126344/characterization-and-longitudinal-monitoring-of-serum-androgens-and-glucocorticoids-during-normal-pregnancy-in-the-killer-whale-orcinus-orca
#18
Todd R Robeck, Karen J Steinman, Justine K O'Brien
The secretory patterns of testosterone (T), androstenedione (A4), dehydroepiandrosterone (DHEA), cortisol (C), and corticosterone (Co) were characterized throughout 28 normal pregnancies until two-months post-partum in eleven killer whales. Effects of fetal sex, dam parity or age, and season were evaluated across either day post-conception (DPC), stage of pregnancy (PRE, EARLY, MID, LATE, POST) or indexed month post-conception (IMPC) using a mixed model linear regression with animal ID and pregnancy number as the random variables...
January 23, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28105741/potential-use-of-cubic-phase-masks-for-extending-the-range-of-clear-vision-in-presbyopes-initial-calculation-and-simulation-studies
#19
Justo Arines, Citlalli Almaguer, Eva Acosta
PURPOSE: In this paper we analyse the potential use of a non-symmetrical optical element, a cubic phase mask, for extending the range of clear vision of presbyopic eyes. Additionally, we will discuss the appropriateness of the visual Strehl ratio to analyse this sort of presbyopic solution based on non-symmetrical phase masks contrasted with through-focus retinal images. METHODS: In order to evaluate the performance of the cubic phase mask we employed computational Fourier Optics to compute the different visual Strehl criteria as well as simulate the retinal images...
January 20, 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28052937/here-and-there-but-not-everywhere-repeated-loss-of-uncoupling-protein-1-in-amniotes
#20
Suzanne McGaugh, Tonia S Schwartz
Endothermy is an evolutionary innovation in eutherian mammals and birds. In eutherian mammals, UCP1 is a key protein in adaptive nonshivering thermogenesis (NST). Although ucp1 arose early in the vertebrate lineage, the loss of ucp1 was previously documented in several reptile species (including birds). Here we determine that ucp1 was lost at the base of the reptile lineage, as we fail to find ucp1 in every major reptile lineage. Furthermore, though UCP1 plays a key role in mammalian NST, we confirm that pig has lost several exons from ucp1 and conclude that pig is not a sole outlier as the only eutherian mammal lineage to do so...
January 2017: Biology Letters
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