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https://www.readbyqxmd.com/read/28187472/-epi-bowman-keratectomy-clinical-evaluation-of-a-new-method-of-surface-ablation
#1
S Taneri, S Kießler, A Rost, T Schultz, M Elling, B Dick
Purpose A new device for epithelial abrasion before excimer laser surface ablation or corneal cross-linking (CXL) has recently been introduced (Epi-Clear™, Orca Surgical, Kiryat-Shmona, Israel). We have reviewed the literature on the clinical results, potential benefits and drawbacks of this instrument, compared to other methods of epithelial removal. Method Literature search for "Epi-Bowman Keratectomy", "Epi-clear", and "Epikeratome" yielded 1 peer-review publication, 1 non-peer-review publication, 18 posters and presentations at international conferences (European Society of Cataract and Refractive Surgeons [ESCRS] and American Society of Cataract and Refractive Surgery [ASCRS]) on the use of the Epi-Clear™ device before surface ablation, 2 posters on the use of Epi-Clear before corneal crosslinking and 1 presentation on the experimental use of Epi-Clear for removal of a pterygium...
February 10, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28126344/characterization-and-longitudinal-monitoring-of-serum-androgens-and-glucocorticoids-during-normal-pregnancy-in-the-killer-whale-orcinus-orca
#2
Todd R Robeck, Karen J Steinman, Justine K O'Brien
The secretory patterns of testosterone (T), androstenedione (A4), dehydroepiandrosterone (DHEA), cortisol (C), and corticosterone (Co) were characterized throughout 28 normal pregnancies until two-months post-partum in eleven killer whales. Effects of fetal sex, dam parity or age, and season were evaluated across either day post-conception (DPC), stage of pregnancy (PRE, EARLY, MID, LATE, POST) or indexed month post-conception (IMPC) using a mixed model linear regression with animal ID and pregnancy number as the random variables...
January 23, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28105741/potential-use-of-cubic-phase-masks-for-extending-the-range-of-clear-vision-in-presbyopes-initial-calculation-and-simulation-studies
#3
Justo Arines, Citlalli Almaguer, Eva Acosta
PURPOSE: In this paper we analyse the potential use of a non-symmetrical optical element, a cubic phase mask, for extending the range of clear vision of presbyopic eyes. Additionally, we will discuss the appropriateness of the visual Strehl ratio to analyse this sort of presbyopic solution based on non-symmetrical phase masks contrasted with through-focus retinal images. METHODS: In order to evaluate the performance of the cubic phase mask we employed computational Fourier Optics to compute the different visual Strehl criteria as well as simulate the retinal images...
January 20, 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28052937/here-and-there-but-not-everywhere-repeated-loss-of-uncoupling-protein-1-in-amniotes
#4
Suzanne McGaugh, Tonia S Schwartz
Endothermy is an evolutionary innovation in eutherian mammals and birds. In eutherian mammals, UCP1 is a key protein in adaptive nonshivering thermogenesis (NST). Although ucp1 arose early in the vertebrate lineage, the loss of ucp1 was previously documented in several reptile species (including birds). Here we determine that ucp1 was lost at the base of the reptile lineage, as we fail to find ucp1 in every major reptile lineage. Furthermore, though UCP1 plays a key role in mammalian NST, we confirm that pig has lost several exons from ucp1 and conclude that pig is not a sole outlier as the only eutherian mammal lineage to do so...
January 2017: Biology Letters
https://www.readbyqxmd.com/read/27966947/massively-parallel-implementation-of-explicitly-correlated-coupled-cluster-singles-and-doubles-using-tiledarray-framework
#5
Chong Peng, Justus A Calvin, Fabijan Pavošević, Jinmei Zhang, Edward F Valeev
A new distributed-memory massively parallel implementation of standard and explicitly correlated (F12) coupled-cluster singles and doubles (CCSD) with canonical O(N(6)) computational complexity is described. The implementation is based on the TiledArray tensor framework. Novel features of the implementation include (a) all data greater than O(N) is distributed in memory and (b) the mixed use of density fitting and integral-driven formulations that optionally allows to avoid storage of tensors with three and four unoccupied indices...
December 29, 2016: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/27924004/temporal-association-of-orca-lrwd1-to-late-firing-origins-during-g1-dictates-heterochromatin-replication-and-organization
#6
Yating Wang, Abid Khan, Anna B Marks, Owen K Smith, Sumanprava Giri, Yo-Chuen Lin, Rachel Creager, David M MacAlpine, Kannanganattu V Prasanth, Mirit I Aladjem, Supriya G Prasanth
DNA replication requires the recruitment of a pre-replication complex facilitated by Origin Recognition Complex (ORC) onto the chromatin during G1 phase of the cell cycle. The ORC-associated protein (ORCA/LRWD1) stabilizes ORC on chromatin. Here, we evaluated the genome-wide distribution of ORCA using ChIP-seq during specific time points of G1. ORCA binding sites on the G1 chromatin are dynamic and temporally regulated. ORCA association to specific genomic sites decreases as the cells progressed towards S-phase...
December 6, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27923044/killer-whale-orcinus-orca-predation-on-beaked-whales-mesoplodon-spp-in-the-bremer-sub-basin-western-australia
#7
Rebecca Wellard, Keith Lightbody, Leila Fouda, Michelle Blewitt, David Riggs, Christine Erbe
Observations of killer whales (Orcinus orca) feeding on the remains of beaked whales have been previously documented; however, to date, there has been no published account of killer whales actively preying upon beaked whales. This article describes the first field observations of killer whales interacting with, hunting and preying upon beaked whales (Mesoplodon spp.) on four separate occasions during 2014, 2015 and 2016 in the Bremer Sub-Basin, off the south coast of Western Australia.
2016: PloS One
https://www.readbyqxmd.com/read/27907916/orca-announcements
#8
Zsuzsanna Tóth
No abstract text is available yet for this article.
2016: Caries Research
https://www.readbyqxmd.com/read/27870149/development-of-sociality-and-emergence-of-independence-in-a-killer-whale-orcinus-orca-calf-from-birth-to-36-months
#9
Sara Guarino, Heather M Hill, Julie Sigman
Dolphin calves spend most of their time swimming with their mother immediately after birth. As they mature, the calves become increasingly independent, and begin to interact more often with other calves, juveniles, and sub-adults. For bottlenose dolphin calves, sociality is related to maternal behaviors. Unfortunately, much less is known about the development of sociality and emergence of independence for killer whale calves. The purpose of this study was to examine the developmental changes in social behaviors and solitary activities of a killer whale calf across a 36-month period...
November 21, 2016: Zoo Biology
https://www.readbyqxmd.com/read/27801944/a-differentially-regulated-ap2-erf-transcription-factor-gene-cluster-acts-downstream-of-a-map-kinase-cascade-to-modulate-terpenoid-indole-alkaloid-biosynthesis-in-catharanthus-roseus
#10
Priyanka Paul, Sanjay K Singh, Barunava Patra, Xueyi Sui, Sitakanta Pattanaik, Ling Yuan
Catharanthus roseus produces bioactive terpenoid indole alkaloids (TIAs), including the chemotherapeutics, vincristine and vinblastine. Transcriptional regulation of TIA biosynthesis is not fully understood. The jasmonic acid (JA)-responsive AP2/ERF transcription factor (TF), ORCA3, and its regulator, CrMYC2, play key roles in TIA biosynthesis. ORCA3 forms a physical cluster with two uncharacterized AP2/ERFs, ORCA4 and 5. Here, we report that (1) the ORCA gene cluster is differentially regulated; (2) ORCA4, while overlapping functionally with ORCA3, modulates an additional set of TIA genes...
November 1, 2016: New Phytologist
https://www.readbyqxmd.com/read/27770983/conservation-status-of-killer-whales-orcinus-orca-in-the-strait-of-gibraltar
#11
R Esteban, P Verborgh, P Gauffier, D Alarcón, J M Salazar-Sierra, J Giménez, A D Foote, R de Stephanis
Killer whales (Orcinus orca) in the Mediterranean Sea are currently restricted to the Strait of Gibraltar and surrounding waters. Thirty-nine individuals were present in 2011, with a well-differentiated social structure, organized into five pods. Killer whale occurrence in the Strait is apparently related to the migration of their main prey, Atlantic bluefin tuna (Thunnus thynnus). In spring, whale distribution was restricted to shallow waters off the western coast of the Strait where all pods were observed actively hunting tuna...
2016: Advances in Marine Biology
https://www.readbyqxmd.com/read/27770981/marine-mammals-in-the-mediterranean-sea-an-overview
#12
G Notarbartolo di Sciara
Despite being a small part of the world's oceans, the Mediterranean Sea hosts a diverse marine mammal fauna, with a total of 28 different species known to occur, or to have occurred, in the region. Species currently recognised as regular in the Mediterranean-the Mediterranean monk seal (Monachus monachus) and 11 cetaceans (fin whale, Balaenoptera physalus; sperm whale, Physeter macrocephalus; Cuvier's beaked whale, Ziphius cavirostris; short-beaked common dolphin, Delphinus delphis; long-finned pilot whale, Globicephala melas; Risso's dolphin, Grampus griseus; killer whale, Orcinus orca; striped dolphin, Stenella coeruleoalba; rough-toothed dolphin, Steno bredanensis; common bottlenose dolphin, Tursiops truncatus; harbour porpoise, Phocoena phocoena relicta) have adapted well to the region's environmental conditions, but their coexistence with humans is problematic...
2016: Advances in Marine Biology
https://www.readbyqxmd.com/read/27651280/pycpr-a-python-based-implementation-of-the-conjugate-peak-refinement-cpr-algorithm-for-finding-transition-state-structures
#13
Florian J Gisdon, Martin Culka, G Matthias Ullmann
Conjugate peak refinement (CPR) is a powerful and robust method to search transition states on a molecular potential energy surface. Nevertheless, the method was to the best of our knowledge so far only implemented in CHARMM. In this paper, we present PyCPR, a new Python-based implementation of the CPR algorithm within the pDynamo framework. We provide a detailed description of the theory underlying our implementation and discuss the different parts of the implementation. The method is applied to two different problems...
October 2016: Journal of Molecular Modeling
https://www.readbyqxmd.com/read/27636553/androgen-and-glucocorticoid-production-in-the-male-killer-whale-orcinus-orca-influence-of-age-maturity-and-environmental-factors
#14
J K O'Brien, K J Steinman, G A Fetter, T R Robeck
Circulating concentrations of testosterone and its precursor androstenedione, as well as dehydroepiandrosterone (DHEA) and the adrenal hormones cortisol and corticosterone were measured at monthly intervals in 14 male killer whales (Orcinus orca) aged 0.8-38 years. Analyses were performed for examination of the relationships of age, sexual maturation status (STATUS), season, and environmental temperature (monthly air ambient temperature, A-TEMP) with hormone production using a mixed effects linear regression model with animal ID as the random variable...
January 2017: Andrology
https://www.readbyqxmd.com/read/27632287/supporting-risk-assessment-accounting-for-indirect-risk-to-ecosystem-components
#15
Cathryn Clarke Murray, Megan E Mach, Rebecca G Martone, Gerald G Singh, Miriam O, Kai M A Chan
The multi-scalar complexity of social-ecological systems makes it challenging to quantify impacts from human activities on ecosystems, inspiring risk-based approaches to assessments of potential effects of human activities on valued ecosystem components. Risk assessments do not commonly include the risk from indirect effects as mediated via habitat and prey. In this case study from British Columbia, Canada, we illustrate how such "indirect risks" can be incorporated into risk assessments for seventeen ecosystem components...
2016: PloS One
https://www.readbyqxmd.com/read/27597842/phylogeography-salinity-adaptations-and-metabolic-potential-of-the-candidate-division-kb1-bacteria-based-on-a-partial-single-cell-genome
#16
Lisa M Nigro, Andrew S Hyde, Barbara J MacGregor, Andreas Teske
Deep-sea hypersaline anoxic basins and other hypersaline environments contain abundant and diverse microbial life that has adapted to these extreme conditions. The bacterial Candidate Division KB1 represents one of several uncultured groups that have been consistently observed in hypersaline microbial diversity studies. Here we report the phylogeography of KB1, its phylogenetic relationships to Candidate Division OP1 Bacteria, and its potential metabolic and osmotic stress adaptations based on a partial single cell amplified genome of KB1 from Orca Basin, the largest hypersaline seafloor brine basin in the Gulf of Mexico...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27548232/orca-behavior-and-subsequent-aggression-associated-with-oceanarium-confinement
#17
Robert Anderson, Robyn Waayers, Andrew Knight
Based on neuroanatomical indices such as brain size and encephalization quotient, orcas are among the most intelligent animals on Earth. They display a range of complex behaviors indicative of social intelligence, but these are difficult to study in the open ocean where protective laws may apply, or in captivity, where access is constrained for commercial and safety reasons. From 1979 to 1980, however, we were able to interact with juvenile orcas in an unstructured way at San Diego's SeaWorld facility. We observed in the animals what appeared to be pranks, tests of trust, limited use of tactical deception, emotional self-control, and empathetic behaviors...
August 18, 2016: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/27547372/dietary-habits-of-polar-bears-in-foxe-basin-canada-possible-evidence-of-a-trophic-regime-shift-mediated-by-a-new-top-predator
#18
Melissa P Galicia, Gregory W Thiemann, Markus G Dyck, Steven H Ferguson, Jeff W Higdon
Polar bear (Ursus maritimus) subpopulations in several areas with seasonal sea ice regimes have shown declines in body condition, reproductive rates, or abundance as a result of declining sea ice habitat. In the Foxe Basin region of Nunavut, Canada, the size of the polar bear subpopulation has remained largely stable over the past 20 years, despite concurrent declines in sea ice habitat. We used fatty acid analysis to examine polar bear feeding habits in Foxe Basin and thus potentially identify ecological factors contributing to population stability...
August 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/27536700/comparative-in-silico-study-of-sex-determining-region-y-sry-protein-sequences-involved-in-sex-determining
#19
Masoume Vakili Azghandi, Mohammadreza Nasiri, Ali Shamsa, Mohsen Jalali, Mohammad Mahdi Shariati
BACKGROUND: The SRY gene (SRY) provides instructions for making a transcription factor called the sex-determining region Y protein. The sex-determining region Y protein causes a fetus to develop as a male. In this study, SRY of 15 spices included of human, chimpanzee, dog, pig, rat, cattle, buffalo, goat, sheep, horse, zebra, frog, urial, dolphin and killer whale were used for determine of bioinformatic differences. METHODS: Nucleotide sequences of SRY were retrieved from the NCBI databank...
April 2016: Reports of Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/27467510/silencing-the-transcriptional-repressor-zct1-illustrates-the-tight-regulation-of-terpenoid-indole-alkaloid-biosynthesis-in-catharanthus-roseus-hairy-roots
#20
Noreen F Rizvi, Jessica D Weaver, Erin J Cram, Carolyn W T Lee-Parsons
The Catharanthus roseus plant is the source of many valuable terpenoid indole alkaloids (TIAs), including the anticancer compounds vinblastine and vincristine. Transcription factors (TFs) are promising metabolic engineering targets due to their ability to regulate multiple biosynthetic pathway genes. To increase TIA biosynthesis, we elicited the TIA transcriptional activators (ORCAs and other unidentified TFs) with the plant hormone, methyl jasmonate (MJ), while simultaneously silencing the expression of the transcriptional repressor ZCT1...
2016: PloS One
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