Read by QxMD icon Read


(no author information available yet)
No abstract text is available yet for this article.
March 2018: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
(no author information available yet)
No abstract text is available yet for this article.
March 2018: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
Liqun Xing, Lichao Wang, Rui Zhang
It has become a great habit for driving to work in people's daily life in China. In order to understand the concentration of volatile organic compounds (VOCs) in vehicles and the health risks related to inhalation exposure to VOCs, this study investigated the pollution characteristics and health risks posed by VOCs emitted from interior materials in vehicles. A total of 47 of 62 VOCs were studied, using 23 randomly selected vehicles of different brands in Nanjing city, China. The potential cancer and non-cancer health risks associated with VOC inhalation were assessed based on conventional approaches proposed by the United States Environmental Protection Agency (USEPA)...
March 14, 2018: Environmental Science and Pollution Research International
Yoav Eizenberg, Ehud Grossman, David Tanne, Silvia Koton
The impact of beta-blockers (BB) treatment on stroke outcome is unclear. We used data from a prospective national stroke registry to assess the associations between use of BB and poor outcome 3 months after stroke. Using the National Acute Stroke Israeli (NASIS) registry, we identified 1126 patients with ischemic stroke and intracerebral hemorrhage with pre-stroke hypertension treatment, who were followed for 3-months. Functional outcome and mortality at 3-month were compared by use of BB, adjusting for demographics and clinical factors...
March 9, 2018: Journal of Clinical Hypertension
Seiji Ohtori, Sumihisa Orita, Yawara Eguchi, Yasuchika Aoki, Miyako Suzuki, Gou Kubota, Kazuhide Inage, Yasuhiro Shiga, Koki Abe, Hideyuki Kinoshita, Masahiro Inoue, Hirohito Kanamoto, Masaki Norimoto, Tomotaka Umimura, Takeo Furuya, Koda Masao, Satoshi Maki, Tsutomu Akazawa, Kazuhisa Takahashi
STUDY DESIGN: A retrospective study. OBJECTIVE: The aim of this study was to determine the publication rate and impact factors (IFs) among all abstracts presented at the 2010 and 2012 meetings of the International Society for the Study of Lumbar Spine (ISSLS). SUMMARY OF BACKGROUND DATA: The publication rate of abstracts presented at overseas meetings was reported to be around 50%. However, the publication rate and IFs of oral and poster presentations made at ISSLS meetings were unclear...
March 5, 2018: Spine
Otto A Sanchez, Laine K Ferrara, Sarah Rein, Danielle Berglund, Arthur J Matas, Hassan N Ibrahim
Incidence of post-donation hypertension, risk factors associated with its development and impact of type of treatment received on renal outcomes were determined in 3700 kidney donors. Using Cox proportional hazard model, adjusted hazard ratios (HRs) for cardiovascular disease (CVD), estimated glomerular filtration rate (eGFR) <60, <45, <30 mL/min/1.73m2 , end stage renal disease (ESRD) and death in hypertensive donors were determined. After a mean (SD) of 16.6 (11.9) years of follow-up, 1126 (26.8%) donors developed hypertension and 894 were receiving anti-hypertensive medications...
March 2, 2018: American Journal of Transplantation
Omnia Gamal El-Dien, Blaise Ratcliffe, Jaroslav Klápště, Ilga Porth, Charles Chen, Yousry A El-Kassaby
The advantages of open-pollinated (OP) family testing over controlled crossing (i.e., structured pedigree) are the potential to screen and rank a large number of parents and offspring with minimal cost and efforts; however, the method produces inflated genetic parameters as the actual sibling relatedness within OP families rarely meets the half-sib relatedness assumption. Here, we demonstrate the unsurpassed utility of OP testing after shifting the analytical mode from pedigree- (ABLUP) to genomic-based (GBLUP) relationship using phenotypic tree height (HT) and wood density (WD) and genotypic (30k SNPs) data for 1126 38-year-old Interior spruce ( Picea glauca (Moench) Voss x P...
2018: Molecular Breeding: New Strategies in Plant Improvement
Godai Suzuki, Yang Wang, Karen Kubo, Eri Hirata, Shinsuke Ohnuki, Yoshikazu Ohya
BACKGROUND: The size of the phenotypic effect of a gene has been thoroughly investigated in terms of fitness and specific morphological traits in the budding yeast Saccharomyces cerevisiae, but little is known about gross morphological abnormalities. RESULTS: We identified 1126 holistic morphological effectors that cause severe gross morphological abnormality when deleted, and 2241 specific morphological effectors with weak holistic effects but distinctive effects on yeast morphology...
February 20, 2018: BMC Genomics
David A Kalmbach, Vivek Pillai, Christopher L Drake
Nearly half of US adults endorse insomnia symptoms. Sleep problems increase risk for depression during stress, but the mechanisms are unclear. During high stress, individuals having difficulty falling or staying asleep may be vulnerable to cognitive intrusions after stressful events, given that the inability to sleep creates a period of unstructured and socially isolated time in bed. We investigated the unique and combined effects of insomnia symptoms and stress-induced cognitive intrusions on risk for incident depression...
2018: PloS One
Stefano Vezzoli, Vincenzo Bruno, Clayton DeVault, Thomas Roger, Vladimir M Shalaev, Alexandra Boltasseva, Marcello Ferrera, Matteo Clerici, Audrius Dubietis, Daniele Faccio
Materials with a spatially uniform but temporally varying optical response have applications ranging from magnetic field-free optical isolators to fundamental studies of quantum field theories. However, these effects typically become relevant only for time variations oscillating at optical frequencies, thus presenting a significant hurdle that severely limits the realization of such conditions. Here we present a thin-film material with a permittivity that pulsates (uniformly in space) at optical frequencies and realizes a time-reversing medium of the form originally proposed by Pendry [Science 322, 71 (2008)SCIEAS0036-807510...
January 26, 2018: Physical Review Letters
Jian Xu, Xuelian Xiao, Daheng Yang
MicroRNAs (miRNAs) are small noncoding, single-stranded RNAs consisting of 20-24 nucleotides (Bartel, Cell 116:281-297, 2004), which regulate target genes expression by interacting with 3'-untranslated regions (3'-UTRs) of target mRNAs, leading to translation repression or mRNA degradation (Filipowicz et al., Nat Rev Genet 9:102-114, 2008; Nilsen, Trends Genet 23:243-249, 2007). Accumulating evidence has elucidated them as oncogenes or tumor suppressors in cancers such as hepatocellular carcinoma, breast cancer, and lung cancer (Liu et al...
2018: Methods in Molecular Biology
W M Oo, J M Linklater, M Daniel, S Saarakkala, J Samuels, P G Conaghan, H I Keen, L A Deveza, D J Hunter
OBJECTIVE: The aims of this study were to systematically review clinimetrics of commonly assessed ultrasound pathologies in knee, hip and hand osteoarthritis (OA), and to conduct a meta-analysis for each clinimetric. METHODS: Medline, Embase, and Cochrane Library databases were searched from their inceptions to September 2016. According to the Outcome Measures in Rheumatology (OMERACT) Instrument Selection Algorithm, data extraction focused on ultrasound technical features and performance metrics...
February 7, 2018: Osteoarthritis and Cartilage
Patricia M Horvath, Lisa M Monteggia
Rett syndrome is a neurodevelopmental disorder that primarily affects females and is caused by mutations in the methyl-CpG-binding-protein 2 (MECP2) gene. Initially, MeCP2 had been shown to be a repressor of gene transcription. In their 2008 paper, Chahrour and colleagues (DOI: 10.1126/science.1153252) reported that MeCP2 could also function as a transcriptional activator.
February 2018: Trends in Neurosciences
Iveta Pugajeva, Jeļena Avsejenko, Elza Judjallo, Aivars Bērziņš, Elena Bartkiene, Vadims Bartkevics
An ultra-sensitive mass spectrometric confirmation and quantification method for the determination of selected fluoroquinolones - enrofloxacin and its main metabolite ciprofloxacin - was developed and validated in poultry meat samples. The achieved limits of quantification were 1 ng kg-1 for enrofloxacin and 10 ng kg-1 for ciprofloxacin. The analysis of 40 retail poultry samples originating from Estonia, Latvia, Lithuania, Poland and France, revealed that 93% of samples contained residues of enrofloxacin in range from 3...
January 29, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Stefan Christensen, Peter Buggisch, Stefan Mauss, Klaus H W Böker, Eckart Schott, Hartwig Klinker, Tim Zimmermann, Bernd Weber, Jens Reimer, Yvonne Serfert, Heiner Wedemeyer
BACKGROUND AND AIMS: There is limited real-world information on the effectiveness of antiviral treatment of chronic hepatitis C virus (HCV) infection with direct-acting antivirals (DAA) in people on opioid substitution therapy (OST). This study compared sustained virological response (SVR) rates and proportion of lost to follow-up (LTFU) between OST and non-OST patients in the German Hepatitis C-Registry (DHC-R). DESIGN: National multi-centre prospective real-world registry (German Hepatitis C-Registry, DHC-R)...
January 23, 2018: Addiction
Mankei Tsang
A thought-provoking proposal by Tsakmakidis et al. [Science356, 1260 (2017)SCIEAS0036-807510.1126/science.aam6662] suggests that nonreciprocal optics can break a time-bandwidth limit to passive resonators. Here I quantize their resonator model and show that quantum mechanics does impose a limit, or requires extra noise to be added in the same fashion as amplified spontaneous emission in an active resonator. I also use thermodynamics to argue that extra dissipation or noise must be present in their proposed device...
January 1, 2018: Optics Letters
Lillian Barra, Tahir Kanji, Jacqueline Malette, Christian Pagnoux
BACKGROUND: Early diagnosis of Takayasu's Arteritis (TAK) and detection of disease activity may reduce the risk of vascular complications. The objective of this study was to determine the effectiveness of imaging modalities for the management of TAK. METHODS: MEDLINE and EMBASE were searched for studies of patients undergoing various imaging modalities for TAK diagnosis or to assess disease activity. We excluded case reports, reviews and case series with <10 patients...
February 2018: Autoimmunity Reviews
Matteo Fadel, Jordi Tura
We present a method to certify the presence of Bell correlations in experimentally observed statistics, and to obtain new Bell inequalities. Our approach is based on relaxing the conditions defining the set of correlations obeying a local hidden variable model, yielding a convergent hierarchy of semidefinite programs (SDP's). Because the size of these SDP's is independent of the number of parties involved, this technique allows us to characterize correlations in many-body systems. As an example, we illustrate our method with the experimental data presented in Science 352, 441 (2016)SCIEAS0036-807510...
December 8, 2017: Physical Review Letters
Alexander Singer, Sergio Fanella, Leanne Kosowan, Jamie Falk, Brenden Dufault, Kevin Hamilton, Ashley Walus
Background: Antimicrobial stewardship (AS) programs promote the optimal use of antimicrobials and safe patient care. With most antimicrobials prescribed in the ambulatory setting, establishing benchmark data is imperative to gauge the impact of future AS initiatives. Objectives: To determine the frequency of potentially inappropriate antimicrobial prescribing in primary care practices in Manitoba, Canada and to assess the association between potentially inappropriate antimicrobial prescribing and patient, prescriber and practice-related factors...
December 10, 2017: Family Practice
Josefin Sundh, Philip Wireklint, Mikael Hasselgren, Scott Montgomery, Björn Ställberg, Karin Lisspers, Christer Janson
INTRODUCTION: The aim was to investigate temporal variation in Health-Related Quality of Life (HRQL) and factors influencing low HRQL, in patients with asthma. MATERIAL AND METHODS: Questionnaire data on patient characteristics and the mini-Asthma Quality of Life Questionnaire (mini-AQLQ) scores from two separate cohorts of randomly selected Swedish primary and secondary care asthma patients, in 2005 (n = 1034) and 2015 (n = 1126). Student's t-test and analysis of covariance with adjustment for confounders compared mini-AQLQ total and domain scores in 2005 and 2015...
November 2017: Respiratory Medicine
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"