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Tympanic membrane rupture

M Barclay, R Constable, N R James, P R Thorne, J M Montgomery
Neural activity during early development is known to alter innervation pathways in the central and peripheral nervous systems. We sought to examine how reduced sound-induced sensory activity in the cochlea affected the consolidation of glutamatergic synapses between inner hair cells (IHC) and the primary auditory neurons as these synapses play a primary role in transmitting sound information to the brain. A unilateral conductive hearing loss was induced prior to the onset of sound-mediated stimulation of the sensory hair cells, by rupturing the tympanic membrane and dislocating the auditory ossicles in the left ear of P11 mice...
June 14, 2016: Neuroscience
Cisel Yazgan, Nalan M Aksu
OBJECTIVE: To present the radiological features of blast-related injuries in the victims of the 10 October 2015 Ankara bombing and emphasize the importance of imaging. METHODS: This retrospective descriptive study included a total of 28 patients who underwent CT scan or radiographic imaging within 6 h after the bombing on 10 October 2015. CT scans and plain radiographs were evaluated regarding mechanisms of injuries. Injuries were categorized as primary, secondary, tertiary and quaternary...
June 2016: British Journal of Radiology
Ryan E Rebowe, Patrick Harbour, Jeffrey E Carter, Joseph Andrew Molnar
Tannerite(®) is a proprietary blend of an oxidizer, ammonium nitrate, and aluminum powder catalyst used to make homemade exploding targets. While it is currently approved for unrestricted sale in the United States, it can be used to form devices capable of inflicting major blast injury. We present here a case of close proximity exposure to detonation of the mixed Tannerite(®) blend. In our patient, the exposure lead to injuries typical of blast injury, such as tympanic membrane rupture, globe injury, and severe burns...
June 2016: Burns: Journal of the International Society for Burn Injuries
Rong Z Gan, Don Nakmali, Xiao D Ji, Kegan Leckness, Zachary Yokell
Mechanical damage to middle ear components in blast exposure directly causes hearing loss, and the rupture of the tympanic membrane (TM) is the most frequent injury of the ear. However, it is unclear how the severity of injury graded by different patterns of TM rupture is related to the overpressure waveforms induced by blast waves. In the present study, the relationship between the TM rupture threshold and the impulse or overpressure waveform has been investigated in chinchillas. Two groups of animals were exposed to blast overpressure simulated in our lab under two conditions: open field and shielded with a stainless steel cup covering the animal head...
January 22, 2016: Hearing Research
David A Maerz, Daniel M Gainsburg
No abstract text is available yet for this article.
June 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
George Psillas, Argyrios Krommydas, Georgia Karayannopoulou, Kyriakos Chatzopoulos, Jean Kanitakis, Konstantinos Markou
Ceruminous adenomas are benign tumors that are rare in humans and present with a nonspecific symptomatology. The treatment of choice is surgical excision. We present an 87-year-old woman who presented with a reddish, tender, round, soft mass of the outer third of the inferior wall of the left external auditory canal, discharging a yellowish fluid upon pressure. Coincidentally, due to her poor general condition, this patient also showed symptoms consistent with chronic otitis media, parotitis, and cervical lymphadenopathy, such as otorrhea, through a ruptured tympanic membrane and swelling of the parotid gland and cervical lymph nodes...
2015: Case Reports in Medicine
Owen J O'Neill, Erica D Weitzner
Eustachian tube dysfunction (ETD) and middle ear barotrauma (MEB) are the two most common complications of clinical hyperbaric oxygen (HBO2) treatment. The current grading system, the Teed's Classification, was first described in 1944 with modifications to this system over the years, but none are specific for the evaluation and treatment of patients undergoing clinical HBO2 therapy. Currently, the standard of care is a baseline otoscopic examination performed prior to starting HBO2 therapy. Repeat otoscopy is required for patients having ETD, pain or other symptoms during the compression and/or decompression phase of the treatment...
May 2015: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
Mark van der Linden, Matthias Imöhl, Andreas Busse, Markus Rose, Dieter Adam
UNLABELLED: Otitis media is a common pediatric disease and the main reason for antibiotic prescription in children. Before implementation of routine childhood pneumococcal vaccination in Germany, serotypes contained in the seven-valent pneumococcal conjugate vaccine (PCV) were among the most frequent pneumococcal serotypes responsible for acute otitis media (AOM). This report describes the first 3 years of a prospective, multicenter, epidemiological cross-sectional study examining the bacteriology of middle ear fluids (MEF) and nasopharyngeal swabs (NPS) of children 2 months to 5 years of age with spontaneously perforated AOM in the era of routine pneumococcal vaccination...
March 2015: European Journal of Pediatrics
Nicholas J Scalzitti, Travis J Pfannenstiel
OBJECTIVE: We present a case of a middle-aged male struck by lightning while walking in a parking lot. Assessment of the patient's injuries demonstrated common sequelae of an otologic blast injury. Review of this case should prepare the otolaryngologist to identify and manage otologic blast injuries regardless of their etiology. METHODS: Case study and literature review CASE REPORT: The patient presented to a level 1 trauma and burn center with a ruptured tympanic membrane, otalgia, mixed hearing loss, dizziness, and tinnitus...
December 2014: Otology & Neurotology
Katie W Delk, Johanna Mejia-Fava, David A Jiménez, Marc Kent, Kathern Myrna, Joerg Mayer, Stephen Divers
A 20-year-old Chinese goose (Anser cygnoides) presented for severe left-sided head tilt and circling to the left. Peripheral vestibular disease associated with otitis media extending into the left quadrate bone was diagnosed by magnetic resonance imaging and computed tomography. Otoscopy confirmed a ruptured tympanic membrane, and a brainstem auditory evoked response test confirmed loss of hearing in the affected ear. Surgery to remove the caseous material and long-term medical therapy improved the bird's head tilt and quality of life...
March 2014: Journal of Avian Medicine and Surgery
Chul-Hee Choi
The main objective of this study is to provide an overview of the basic mechanisms of blast induced hearing loss and review pharmacological treatments or interventions that can reduce or inhibit blast induced hearing loss. The mechanisms of blast induced hearing loss have been studied in experimental animal models mimicking features of damage or injury seen in human. Blast induced hearing loss is characterized by perforation and rupture of the tympanic membrane, ossicular damage, basilar membrane damage, inner and outer hair cell loss, rupture of round window, changes in chemical components of cochlear fluid, vasospasm, ischemia, oxidative stress, excitotoxicity, hematoma, and hemorrhage in both animals and humans...
December 2012: Korean Journal of Audiology
James H Lynch, Travis G Deaton
The human body is well adapted to dealing with small variations in atmospheric pressure. However when our pursuit of sport and recreation takes us to extreme altitudes or ocean depths, the change in surrounding pressure has the potential to cause significant morbidity. Sports with more extreme changes in atmospheric pressure such as skydiving and scuba diving commonly place the athlete at risk for barotrauma injuries, especially in the middle ear and sinuses. Middle ear barotrauma occurs when a pressure differential develops between the middle ear and the pressure outside of the tympanic membrane...
March 2014: Current Sports Medicine Reports
Cecilia Engmér Berglin, Göran Laurell, Tobias Bramer, Katarina Edsman, S Allen Counter, Tomas Klason, Andreas Ekborn
OBJECTIVE: To investigate the distribution and elimination of a gadolinium containing high viscosity formulation of sodium hyaluronan (HYA gel) after injection to the middle ear. MATERIALS AND METHODS: The T1 contrast agent gadolinium-diethylenetriamine pentaacetic acid-bis methylamine (Gd-DTPA-BMA) was added to HYA gel and delivered to the middle ear of 13 albino guinea pigs by 3 different ways of injection. Magnetic resonance imaging was performed with a 4.7 T MRI system using a T1-weighted 3-dimentional rapid acquisition with relaxation enhancement sequence...
March 2014: Otology & Neurotology
Peter S Kim, Edward Malin, John C Kirkham, Lydia A Helliwell, Ahmed M S Ibrahim, Adam M Tobias, Joseph Upton, Bernard T Lee, Samuel J Lin
BACKGROUND: On April 15, 2013, at approximately 2:49 p.m. EDT, two improvised explosive devices detonated near the finish line of the 117th Boston Marathon. Patients were transported from the scene to several trauma centers, including the authors' institution. METHODS: Plastic surgical assessment of patients began in the Emergency Department and then rapidly expanded as the scope of the incident became clear. Daily interdisciplinary meetings involving the acute care surgery, orthopedic surgery, plastic surgery, and nursing services were convened in order to coordinate operating room schedules and treatment plans...
November 2013: Plastic and Reconstructive Surgery
Amber L Dougherty, Andrew J MacGregor, Peggy P Han, Erik Viirre, Kevin J Heltemes, Michael R Galarneau
Blast-related ear injuries are a concern during deployment because they can compromise a servicemember's situational awareness and adversely affect operational readiness. The objectives of this study were to describe blast-related ear injuries during Operation Iraqi Freedom, identify the effect of hearing protection worn at the point of injury, and explore hearing loss and tinnitus outcomes within one year after injury. The Expeditionary Medical Encounter Database was used to identify military personnel who survived blast-related injury, and it was linked with outpatient medical databases to obtain diagnoses of hearing loss and tinnitus...
2013: Journal of Rehabilitation Research and Development
Sung-Il Cho, Simon S Gao, Anping Xia, Rosalie Wang, Felipe T Salles, Patrick D Raphael, Homer Abaya, Jacqueline Wachtel, Jongmin Baek, David Jacobs, Matthew N Rasband, John S Oghalai
Given the frequent use of improvised explosive devices (IEDs) around the world, the study of traumatic blast injuries is of increasing interest. The ear is the most common organ affected by blast injury because it is the body's most sensitive pressure transducer. We fabricated a blast chamber to re-create blast profiles similar to that of IEDs and used it to develop a reproducible mouse model to study blast-induced hearing loss. The tympanic membrane was perforated in all mice after blast exposure and found to heal spontaneously...
2013: PloS One
P C Modayil, G W Lloyd, A Mallik, D A Bowdler
Audiovestibular sequelae of electrical injury, due to lightning or electric current, are probably much more common than indicated in literature. The aim of the study was to review the impact of electrical injury on the cochleovestibular system. Studies were identified through Medline, Embase, CINAHL and eMedicine databases. Medical Subject Headings used were 'electrical injury', 'lightning', 'deafness' and 'vertigo'. All prospective and retrospective studies, case series and case reports of patients with cochlear or vestibular damage due to lightning or electrical current injury were included...
May 2014: European Archives of Oto-rhino-laryngology
Emma M M Burkitt Wright, Louise F Porter, Helen L Spencer, Jill Clayton-Smith, Leon Au, Francis L Munier, Sarah Smithson, Mohnish Suri, Marianne Rohrbach, Forbes D C Manson, Graeme C M Black
Brittle cornea syndrome (BCS) is an autosomal recessive disorder characterised by extreme corneal thinning and fragility. Corneal rupture can therefore occur either spontaneously or following minimal trauma in affected patients. Two genes, ZNF469 and PRDM5, have now been identified, in which causative pathogenic mutations collectively account for the condition in nearly all patients with BCS ascertained to date. Therefore, effective molecular diagnosis is now available for affected patients, and those at risk of being heterozygous carriers for BCS...
2013: Orphanet Journal of Rare Diseases
Keith Conover
Earache, a common emergency department presentation, may be caused by a variety of conditions, some distant from the ear. This article discusses the diagnosis and treatment of acute otitis media, otitis media with effusion, otitis externa, otitis media with ruptured tympanic membrane or tympanostomy tubes, malignant otitis externa, mastoiditis and petrositis, traumatic ruptured tympanic membrane, cerumen impactions, and foreign bodies in the ears.
May 2013: Emergency Medicine Clinics of North America
Tadahiko Wada, Michitaka Iwanaga, Nobuhiro Hakuba, Yasuyuki Hiratsuka, Yohei Kumabe, Takao Yoshida, Akihiko Fujita
Our surgical treatment for middle ear cholesteatoma is based on the following 2 concepts: (1) Preservation of the physiological morphology and function of the middle ear, that is, maximal preservation of the posterior wall of the external auditory meatus and the middle ear mucosa and (2) Careful resection of the matrix membrane of the cholesteatoma through the continuity of the matrix membrane. In case the cholesteatoma matrix membrane is ruptured, a staged operation should be performed to prevent the development of residual cholesteatoma from the residual matrix...
February 2013: Nihon Jibiinkoka Gakkai Kaiho
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