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strabismus epidemiology

Alaa AlAli, Stephanie Kletke, Brenda Gallie, Wai-Ching Lam
Retinoblastoma can present in 1 or both eyes and is the most common intraocular malignancy in childhood. It is typically initiated by biallelic mutation of the RB1 tumor suppressor gene, leading to malignant transformation of primitive retinal cells. The most common presentation is leukocoria, followed by strabismus. Heritable retinoblastoma accounts for 45% of all cases, with 80% being bilateral. Treatment and prognosis of retinoblastoma is dictated by the disease stage at initial presentation. The 8th Edition American Joint Committee on Cancer (AJCC) TNMH (tumor, node, metastasis, heritable trait) staging system defines evidence-based clinical and pathological staging for overall prognosis for eye(s) and child...
May 8, 2018: Asia-Pacific Journal of Ophthalmology
Kyung Eun Han, Seung-Hee Baek, Seung-Hyun Kim, Key Hwan Lim
PURPOSE: To evaluate the prevalence and risk factors associated with horizontal strabismus in children and adolescents in South Korea. METHODS: A total of 5,935 children and adolescents 5-18 years of age who participated in the fourth and fifth Korean National Health and Nutrition Examination Survey (KNHANES IV-V) from July 2008 to December 2011 were evaluated and the prevalence of horizontal strabismus was estimated. Univariate and multivariate logistic regression analyses were conducted to determine the association between demographic, socioeconomic and clinical risk factors and clinically significant exodeviation (≥15 prism diopters [PD]) and esodeviation (≥10 PD)...
2018: PloS One
Sarah R Hatt, David A Leske, Kemuel L Philbrick, Jonathan M Holmes
Importance: Health-related quality of life (HRQOL) typically improves following strabismus surgery. Nevertheless, for some patients, HRQOL does not improve, and reasons for this are unknown. Objective: To identify factors associated with failure of adult strabismus-20 (AS-20) HRQOL scores to improve following strabismus surgery. Design, Setting, and Participants: Prospective observational case series at the Mayo Clinic, Rochester, Minnesota, comprising 276 adults, between July 2012 and August 2016...
January 1, 2018: JAMA Ophthalmology
David L Nash, Nancy N Diehl, Brian G Mohney
PURPOSE: To report the incidence, prevalent subtypes, and clinical characteristics of pediatric nystagmus diagnosed over a 30-year period. DESIGN: Retrospective, population-based study. METHODS: Using the Rochester Epidemiology Project, we reviewed the medical records of all children (<19 years) diagnosed as residents in Olmsted County, Minnesota, with any form of nystagmus from January 1, 1976, through December 31, 2005. RESULTS: Seventy-one children were diagnosed during the 30-year period, yielding an annual incidence of 6...
October 2017: American Journal of Ophthalmology
Maria Domenica Pintore, Francesco Cerutti, Antonio D'Angelo, Cristiano Corona, Paola Gazzuola, Loretta Masoero, Corrado Colombo, Roberto Bona, Carlo Cantile, Simone Peletto, Cristina Casalone, Barbara Iulini
BACKGROUND: A fatal case of meningoencephalitis was reported in a 13-year-old Koninklijk Warmbloed Paard Nederland stallion, suspected of West Nile virus (WNV) infection, in the Piedmont region of Italy. Clinical signs included right head tilt and circling, depression alternated with excitability, fever and lateral strabismus. Combined treatment consisting of dimethylsulfoxide, dexamethasone, sulphonamides and sedative was administered, but because of the poor conditions the horse was euthanatized and submitted for necropsy...
March 7, 2017: Parasites & Vectors
Mahmoud F El-Sahn, David B Granet, Amir Marvasti, Adele Roa, Michael Kinori
PURPOSE: To describe the epidemiology of adult strabismus, its etiology, and treatment methods in patients 60 years and older presenting to a tertiary care center. METHODS: This retrospective chart review study of patients with strabismus was performed at the Ratner Eye Center, University of California-San Diego. Data collected included demographics, etiology of misalignment, alignment in the primary position, binocularity, previous surgical intervention, and treatment methods...
November 1, 2016: Journal of Pediatric Ophthalmology and Strabismus
H M Elflein
BACKGROUND: Amblyopia is the main cause for mostly monocular, impaired vision in childhood. Treatment and prevention of amblyopia is only effective during childhood. Ophthalmological screening of children does not yet exist in Germany. EPIDEMIOLOGY: The prevalence of amblyopia in Germany is 5.6%, which is higher than in reports from studies in Australia; however, the prevalence of amblyopia is not comparable in these studies due to different definitions of amblyopia and the inclusion/exclusion criteria of the study cohorts...
April 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
A I Maraña Pérez, M L Ruiz-Falcó Rojas, V Puertas Martín, J Domínguez Carral, I Carreras Sáez, A Duat Rodríguez, V Sánchez González
INTRODUCTION: Sturge-Weber syndrome is a congenital vascular disorder characterised by facial capillary malformation (port-wine stain) associated with venous and capillary malformations in the brain and eye. Neurological symptoms and alterations in other locations may also be observed. OBJECTIVES: This study describes the clinical and epidemiological characteristics and different treatments in a cohort of patients diagnosed with Sturge-Weber syndrome in a tertiary hospital...
July 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
S Boucher, C Rodier Bonifas, T Mathis, H Janin-Manificat, J Fleury, C Burillon
INTRODUCTION: Retrospective study analyzing clinical characteristics and treatment of children affected by Leber-Coats' disease. METHOD: Children with Leber-Coats' disease seen in Edouard-Herriot Hospital, Lyon, between January 2004 and September 2013 were included. The following clinical characteristics were reported: sex, age at diagnosis, presenting symptom, Shields' stage, treatment used, and visual outcomes. RESULTS: Ten children were included in our study...
February 2016: Journal Français D'ophtalmologie
Yogolelo Asani Bienvenu, Musau Nkola Angel, Mbuyi Musanzayi Sebastien, Cilundika Mulenga Philippe, Kabamba Ngombe Léon, Twite Kabange Eugene, Cham Lubamba Chami, Kalenga Muenze Kayamba Prosper, Speeg-Schatz Claude, Chenge Borasisi Gaby
No abstract text is available yet for this article.
2015: Pan African Medical Journal
O Fakhoury, A Aziz, F Matonti, C Benso, K Belahda, D Denis
OBJECTIVE: The goal of this study was to analyze the epidemiology and maternal, prenatal and perinatal risk factors for congenital cataracts. MATERIALS AND METHODS: We conducted a retrospective study of all consecutive cases of congenital cataracts diagnosed and managed at hôpital Nord Marseille, France. We describe demographic, personal, maternal and familial characteristics of these patients. RESULTS: We identified 59 children with congenital cataract...
April 2015: Journal Français D'ophtalmologie
René Höhn, Ulrike Kottler, Tunde Peto, Maria Blettner, Thomas Münzel, Stefan Blankenberg, Karl J Lackner, Manfred Beutel, Philipp S Wild, Norbert Pfeiffer
PURPOSE: This paper describes the study design, methodology, cohort profile and self-reported diseases in the ophthalmological branch of the Gutenberg Health Study (GHS). METHODS: The GHS is an ongoing, prospective, interdisciplinary, single-center, population-based cohort study in Germany. The main goals of the ophthalmological section are to assess the prevalence and incidence of ocular diseases and to explore risk factors, genetic determinants and associations with systemic diseases and conditions...
2015: PloS One
James D Weisfeld-Adams, Emily A McCourt, George A Diaz, Scott C Oliver
The association between combined methylmalonic acidemia and homocystinuria of cblC type (cobalamin C defect, cblC) and ocular disease is now well recognized, and is a significant component of morbidity and disability associated with the condition. In this review, through collation of historically reported cases of early- and late-onset cblC and previously unreported cases, we have attempted to characterize the epidemiology, clinical features, and pathomechanisms of individual ocular features of cblC. These data suggest that maculopathy and nystagmus with abnormal vision are extremely common and affect the majority of children with early-onset cblC, usually before school age; strabismus and optic atrophy are also seen at relatively high frequency...
April 2015: Molecular Genetics and Metabolism
Fares Samra, J Thomas Paliga, Youssef Tahiri, Linton A Whitaker, Scott P Bartlett, Brian J Forbes, Jesse A Taylor
BACKGROUND: While there is a clear correlation between unilateral coronal synostosis (UCS) and ocular motility abnormalities, the literature provides little information as to the true epidemiology of strabismus, or the underlying etiology of these paralleled pathologies. The purpose of this study is to investigate the rate of oculomotor abnormalities associated with UCS and its management. METHODS: A retrospective review of all patients identified to have single-suture, nonsyndromic UCS treated by fronto-orbital advancement at a tertiary craniofacial referral center from 1977 to 2013 was performed...
April 2015: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
María del Pilar González-Díaz, Agnes M F Wong
The prevalence of strabismus varies according to the population studied, ethnicity, and geographic region. Previous studies of Asian populations have found that, unlike Western populations, esotropia is 2.5 times less common than exotropia. Because of the homogeneous nature of the local populations studied, however, it is difficult to ascertain the real difference in the epidemiology among ethnic groups. The aim of this study was to determine the positive predictive value of referrals for infantile esotropia in otherwise healthy children referred to a tertiary eye care center in a large center in North America that serves a ethnically diverse population of over 8 million...
October 2014: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Carole G Cherfan, Nancy N Diehl, Brian G Mohney
PURPOSE: The purpose of this study was to report the prevalence of dissociated strabismus among a population-based cohort of children diagnosed with all forms of ocular misalignment. METHODS: The medical records of all children (<19 years of age) identified by the resources of the Rochester Epidemiology Project who were diagnosed with strabismus while residing in Olmsted County, Minnesota, from January 1, 1985, through December 31, 1994, were retrospectively reviewed for the prevalence of dissociated vertical (DVD) or horizontal (DHD) deviations...
August 2014: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Z Idrees, I Dooley, G Fahy
Strabismus may result in impaired stereopsis, diplopia, undesirable appearance, amblyopia and negative psychological impact. This study provides epidemiological and surgical outcome information about patients attending University College Hospital Galway requiring strabismus surgery. We report a retrospective analysis of 75 consecutive patients, who underwent horizontal strabismus surgery. Sixty-one (81.3%) patients had clinically significant refractive errors, hyperopia being the most common. Thirty-four (45...
June 2014: Irish Medical Journal
Khin P Kilgore, Román A Barraza, David O Hodge, Jeff A McKenzie, Brian G Mohney
PURPOSE: To assess whether successful surgical intervention for intermittent exotropia, or the timing of intervention, has any effect on the development of mental illness. DESIGN: Retrospective, observational case series. METHODS: All patients (<19 years of age) diagnosed with intermittent exotropia in Olmsted County, Minnesota, from January 1, 1975, through December 31, 1994, were reviewed retrospectively. Potential cases were identified using the resources of the Rochester Epidemiology Project, a medical records database designed to capture data on any patient-physician encounter in Olmsted County, Minnesota...
October 2014: American Journal of Ophthalmology
Sarah L P Weber, Rodrigo B Souza, Lorena G Ribeiro, Marcela F Tavares, Mauro Goldchmit
PURPOSE: To evaluate the frequency and severity of ophthalmic manifestations and associated diseases, as well as the epidemiological data in patients with Williams syndrome. METHODS: The authors prospectively studied 30 patients clinically diagnosed as having Williams syndrome as confirmed by the fluorescence in situ hybridization test. Patient history included gender, age, race, education level, previous illnesses, and surgeries. The ophthalmologic examination included best-corrected visual acuity, dynamic and static refraction, extraocular motility test, stereopsis test (Titmus and Lang), and direct and indirect funduscopy...
July 1, 2014: Journal of Pediatric Ophthalmology and Strabismus
Augusto Antonio Hernández, Kepa Balparda, Ana María Díaz, Ana Paulina Pamplona, Daniel Jiménez, Ana María Londoño
BACKGROUND: The appropriate treatment for a disease requires a deep knowledge in regards to the epidemiology of the most common pathological entities. Therefore, it is important to make studies of clinical and epidemiological characterization in order to establish the evolution of the diseases in the outpatient services. The objective of this study was to perform a clinical and epidemiological characterization of patients evaluated at a pediatric ophthalmology department during the course of twelve months, in Medellín, Colombia...
March 2014: Revista Médica del Instituto Mexicano del Seguro Social
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