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https://www.readbyqxmd.com/read/28434392/does-the-eq-5d-capture-the-concerns-measured-by-the-palliative-care-outcome-scale-mapping-the-palliative-care-outcome-scale-onto-the-eq-5d-using-statistical-methods
#1
Mendwas D Dzingina, Paul McCrone, Irene J Higginson
BACKGROUND: The main measure to generate utility data for economic evaluations is the EQ-5D, but no study has tested whether or how to map from palliative care measures to the EQ-5D. AIMS: To assess the level of conceptual overlap between palliative outcomes and the EQ-5D, and the feasibility of mapping between them to obtain utilities for the Palliative care Outcome Scale. DESIGN: A cross-sectional secondary analysis of data from three studies...
April 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/28431564/effectiveness-of-the-capsaicin-8-patch-in-the-management-of-peripheral-neuropathic-pain-in-european-clinical-practice-the-ascend-study
#2
Colette Mankowski, Chris D Poole, Etienne Ernault, Roger Thomas, Ellen Berni, Craig J Currie, Cecil Treadwell, José I Calvo, Christina Plastira, Eirini Zafeiropoulou, Isaac Odeyemi
BACKGROUND: In randomised studies, the capsaicin 8% patch has demonstrated effective pain relief in patients with peripheral neuropathic pain (PNP) arising from different aetiologies. METHODS: ASCEND was an open-label, non-interventional study of patients with non-diabetes-related PNP who received capsaicin 8% patch treatment, according to usual clinical practice, and were followed for ≤52 weeks. Co-primary endpoints were percentage change in the mean numeric pain rating scale (NPRS) 'average daily pain' score from baseline to the average of Weeks 2 and 8 following first treatment; and median time from first to second treatment...
April 21, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28427471/quality-of-life-and-healthcare-service-utilization-among-methadone-maintenance-patients-in-a-mountainous-area-of-northern-vietnam
#3
Long Hoang Nguyen, Lan Huong Thi Nguyen, Victoria L Boggiano, Canh Dinh Hoang, Hung Van Nguyen, Huong Thi Le, Hai Quan Le, Tho Dinh Tran, Bach Xuan Tran, Carl A Latkin, Nabil Zary, Minh Thuc Thi Vu
BACKGROUND: The expansion of methadone maintenance treatment in mountainous areas in still limited and little is known about its health impacts on drug users. This study aimed to examine health-related quality of life (HRQOL) and health care access among patients engaging in methadone maintenance treatment (MMT) in Tuyen Quang, a mountainous province in Vietnam. METHODS: We conducted a cross-sectional survey with 241 patients conveniently recruited in two MMT clinics (Son Duong and Tuyen Quang)...
April 20, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28426759/health-related-quality-of-life-in-south-african-patients-with-pulmonary-tuberculosis
#4
Tanja Kastien-Hilka, Bernd Rosenkranz, Edina Sinanovic, Bryan Bennett, Matthias Schwenkglenks
BACKGROUND: The evaluation of patient-reported health-related quality of life (HRQOL) in pulmonary tuberculosis (TB) contributes to a comprehensive understanding of the burden associated with this disease. The aim of this study was to assess the overall impact of TB on the health status and on single health domains identified in the WHO definition of health, including physical, mental and social health aspects. METHODS: Four instruments for HRQOL evaluation were applied in a longitudinal multicentre study during six-month standard TB treatment in South Africa...
2017: PloS One
https://www.readbyqxmd.com/read/28425322/determinants-of-health-related-quality-of-life-among-elderly-evidence-from-chi-linh-town-vietnam
#5
Nguyen Thanh Huong, Le Thi Hai Ha, Truong Quang Tien
As Vietnam confronts with the challenge of an aging population, the importance of quality of life for elderly people becomes apparent. This article aims to assess health-related quality of life (HRQoL) and its correlates for the elderly, using a cross-sectional study design. A total of 1599 adults, aged 60 years and older, were drawn from the 2016 baseline survey of Chi Linh Health and Demographic Surveillance System (CHILILAB HDSS), which incorporated the EQ-5D, to measure HRQoL. Data were analyzed using multivariate linear regression analyses...
April 1, 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28424063/clinical-and-cost-effectiveness-analysis-of-early-detection-of-patients-at-nutrition-risk-during-their-hospital-stay-through-the-new-screening-method-cipa-a-study-protocol
#6
José Pablo Suárez-Llanos, Néstor Benítez-Brito, Laura Vallejo-Torres, Irina Delgado-Brito, Adriá Rosat-Rodrigo, Carolina Hernández-Carballo, Yolanda Ramallo-Fariña, Francisca Pereyra-García-Castro, Juan Carlos-Romero, Nieves Felipe-Pérez, Jennifer García-Niebla, Eduardo Mauricio Calderón-Ledezma, Teresa de Jesús González-Melián, Ignacio Llorente-Gómez de Segura, Manuel Ángel Barrera-Gómez
BACKGROUND: Malnutrition is highly prevalent in hospitalized patients and results in a worsened clinical course as well as an increased length of stay, mortality, and costs. Therefore, simple nutrition screening systems, such as CIPA (control of food intake, protein, anthropometry), may be implemented to facilitate the patient's recovery process. The aim of this study is to evaluate the effectiveness and cost-effectiveness of implementing such screening tool in a tertiary hospital, consistent with the lack of similar, published studies on any hospital nutrition screening system...
April 20, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28423480/the-effect-of-high-dose-vitamin-d-supplementation-on-muscular-function-and-quality-of-life-in-postmenopausal-women-a-randomized-controlled-trial
#7
G Grimnes, N Emaus, K D Cashman, R Jorde
OBJECTIVE: Observational studies have suggested positive associations between serum 25-hydroxyvitamin D (25(OH)D) levels and muscular strength, balance and quality of life. Our aim was to examine whether high-dose vitamin D supplementation would improve these measures as compared to standard-dose vitamin D, as well as the possible muscular effects of Single Nucleotide Polymorphisms (SNPs) in genes encoding vitamin D-related enzymes. DESIGN: A 12-month randomized, double-blind, controlled trial where the participants received daily elemental calcium (1,000 mg) plus vitamin D3 (800 IU)...
April 19, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28420153/health-related-quality-of-life-of-the-general-german-population-in-2015-results-from-the-eq-5d-5l
#8
Manuel B Huber, Julia Felix, Martin Vogelmann, Reiner Leidl
The EQ-5D-5L is a widely used generic instrument to measure health-related quality of life. This study evaluates health perception in a representative sample of the general German population from 2015. To compare results over time, a component analysis technique was used that separates changes in the description and valuation of health states. The whole sample and also subgroups, stratified by sociodemographic parameters as well as disease affliction, were analyzed. In total, 2040 questionnaires (48.4% male, mean age 47...
April 16, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28419637/self-reported-prevalence-description-and-management-of-pain-in-adults-with-haemophilia-methods-demographics-and-results-from-the-pain-functional-impairment-and-quality-of-life-p-fiq-study
#9
M Witkop, A Neff, T W Buckner, M Wang, K Batt, C M Kessler, D Quon, L Boggio, M Recht, K Baumann, R Z Gut, D L Cooper, C L Kempton
INTRODUCTION: Haemophilia is characterized by frequent haemarthrosis, leading to acute/chronic joint pain. AIM: To assess self-reported prevalence, description and management of pain in adult males with mild-to-severe haemophilia and history of joint pain/bleeding. METHODS: Participants completed a pain survey and five patient-reported outcome instruments assessing pain, functional impairment and health-related quality of life (HRQoL). RESULTS: Of 381 participants enrolled, median age was 34 years; 77% had haemophilia A, 71% had severe disease and 65% were overweight/obese...
April 16, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28416835/-polymethylmethacrylate-augmentation-of-bone-cement-injectable-cannulated-pedicle-screws-was-used-to-treat-degenerative-lumbar-scoliosis-with-osteoporosis
#10
H L Sun, C D Li, X W Li, X D Yi, H Liu, H L Lu, H Li, Z R Yu, Y Wang
OBJECTIVE: To describe the application of polymethylmethacrylate (PMMA) augmentation of cement-injectable cannulated pedicle screws for the treatment of degenerative lumbar scoliosis with osteoporosis. METHODS: Retrospective cohort study was used to compare cement injectable cannulated pedicle screws (CICPs) group with PMMA augmentation and control group with traditional method in the correction surgery for Lenke-silva level III and level IV degenerative scoliosis cases with osteoporosis...
April 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28416015/costs-and-health-related-quality-of-life-in-alpha-1-antitrypsin-deficient-copd-patients
#11
Florian M Karl, Rolf Holle, Robert Bals, Timm Greulich, Rudolf A Jörres, Annika Karch, Armin Koch, Stefan Karrasch, Reiner Leidl, Holger Schulz, Claus Vogelmeier, Margarethe E Wacker
BACKGROUND: Alpha-1-Antitrypsin Deficiency (AATD) is an economically unexplored genetic disease. METHODS: Direct and indirect costs (based on self-reported information on healthcare utilization) and health-related quality of life (HRQL, as assessed by SGRQ, CAT, and EQ-5D-3 L) were compared between 131 AATD patients (106 with, 25 without augmentation therapy (AT)) and 2,049 COPD patients without AATD participating in the COSYCONET COPD cohort. The medication costs of AT were excluded from all analyses to reveal differences associated with morbidity profiles...
April 17, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28414745/mapping-the-srs-22r-questionnaire-onto-the-eq-5d-5l-utility-score-in-patients-with-adolescent-idiopathic-scoliosis
#12
Carlos King Ho Wong, Prudence Wing Hang Cheung, Dino Samartzis, Keith Dip-Kei Luk, Kenneth M C Cheung, Cindy Lo Kuen Lam, Jason Pui Yin Cheung
This is a prospective study to establish prediction models that map the refined Scoliosis Research Society 22-item (SRS-22r) onto EuroQoL-5 dimension 5-level (EQ-5D-5L) utility scores in adolescent idiopathic scoliosis (AIS) patients. Comparison of treatment outcomes in AIS can be determined by cost-utility analysis. However, the mainstay spine-specific health-related quality of life outcome measure, the SRS-22r questionnaire does not provide utility assessment. In this study, AIS patients were prospectively recruited to complete both the EQ-5D-5L and SRS-22r questionnaires by trained interviewers...
2017: PloS One
https://www.readbyqxmd.com/read/28413830/an-observational-study-on-surgically-treated-adult-idiopathic-scoliosis-patients-quality-of-life-outcomes-at-1-and-2-year-follow-ups-and-comparison-to-controls
#13
Jennifer C Theis, Anna Grauers, Elias Diarbakerli, Panayiotis Savvides, Allan Abbott, Paul Gerdhem
BACKGROUND: Prospective data on health-related quality of life in patients with idiopathic scoliosis treated surgically as adults is needed. We compared preoperative and 1- and 2-year follow-up data in surgically treated adults with idiopathic scoliosis with juvenile or adolescent onset. Results were compared to untreated adults with scoliosis and population normative data. METHODS: A comparison of preoperative and 1- and 2-year follow-up data of 75 adults surgically treated for idiopathic scoliosis at a mean age of 28 years (range 18 to 69) from a prospective national register study, as well as a comparison with age- and sex-matched data from 75 untreated adults with less severe scoliosis and 75 adults without scoliosis, was made...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28410808/questioning-the-differences-between-general-public-vs-patient-based-preferences-towards-eq-5d-5l-defined-hypothetical-health-states
#14
Marko Ogorevc, Nika Murovec, Natacha Bolanos Fernandez, Valentina Prevolnik Rupel
The purpose of this article is to explore whether any differences exist between the general population and patient based preferences towards EQ-5D-5L defined hypothetical health states. The article discusses the role of adaptation and self-interest in valuing health states and it also contributes rigorous empirical evidence to the scientific debate on the differences between the patient and general population preferences towards hypothetical health states. Patient preferences were elicited in 2015 with the EQ-5D-5L questionnaire using time trade-off and discrete choice experiment design and compared to the Spanish general population preferences, which were elicited using identical methods...
March 28, 2017: Health Policy
https://www.readbyqxmd.com/read/28410779/quantifying-health-utilities-in-patients-undergoing-stereotactic-body-radiation-treatment-for-liver-metastases-for-use-in-future-economic-evaluations
#15
B Warren, P Munoz-Schuffenegger, K K W Chan, W Chu, J Helou, D Erler, H Chung
AIM: Stereotactic body radiation therapy (SBRT) is increasingly used as an option for those with liver metastases. In order to facilitate future economic impact of health technologies, health utility scores may be used. The EuroQOL-5D-3L (EQ-5D) preference-based healthy utility instrument was used to evaluate the impact of treatment with SBRT on health utility scores. MATERIALS AND METHODS: Between August 2013 and October 2014, 31 patients treated with 3-5 fractions of SBRT for liver metastases were enrolled in this study...
April 12, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28410761/impact-of-surgical-site-infection-on-healthcare-costs-and-patient-outcomes-a-systematic-review-in-six-european-countries
#16
REVIEW
J M Badia, A L Casey, N Petrosillo, P M Hudson, S A Mitchell, C Crosby
BACKGROUND: Surgical site infections (SSIs) are associated with increased morbidity and mortality. Furthermore, SSIs constitute a financial burden and negatively impact on patient quality of life (QoL). AIM: To assess, and evaluate the evidence for, the cost and health-related QoL (HRQoL) burden of SSIs across various surgical specialties in six European countries. METHODS: Electronic databases and conference proceedings were systematically searched to identify studies reporting the cost and HRQoL burden of SSIs...
March 8, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28410604/the-association-of-patient-and-trauma-characteristics-with-the-health-related-quality-of-life-in-a-dutch-trauma-population
#17
Amy Gunning, Mark van Heijl, Karlijn van Wessem, Luke Leenen
BACKGROUND: It is suggested in literature to use the Health Related Quality of Life (HRQoL) as an outcome indicator for evaluating trauma centre performances. In order to predict HRQoL, characteristics that could be of influence on a predictive model should be identified. This study identifies patient and injury characteristics associated with the HRQoL in a general trauma population. METHODS: Retrospective study of trauma patients admitted from 1st January 2007 through 31th December 2012...
April 14, 2017: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/28410572/incidence-of-infection-following-internal-fixation-of-open-and-closed-tibia-fractures-in-india-infiniti-a-multi-centre-observational-cohort-study
#18
Prakash Doshi, Hitesh Gopalan, Sheila Sprague, Chetan Pradhan, Sunil Kulkarni, Mohit Bhandari
BACKGROUND: Trauma is a major public health problem, particularly in India due to the country's rapid urbanization. Tibia fractures are a common and often complicated injury that is at risk of infection following surgical fixation. The primary objectives of this cohort study were to determine the incidence of infection within one year of surgery and to describe the distribution of infections by location and time of diagnosis for tibia fractures in India. METHODS: We conducted a multi-center, prospective cohort study...
April 14, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28409481/views-of-the-uk-general-public-on-important-aspects-of-health-not-captured-by-eq-5d
#19
Koonal Kirit Shah, Brendan Mulhern, Louise Longworth, M F Janssen
INTRODUCTION: The EQ-5D is a standardised instrument designed for use as a generic measure of health outcome. It was (and is) intended to provide information about a 'common core' of dimensions known to be relevant across a range of conditions; however, the five dimensions may not fully capture the health-related impacts of certain conditions. This study analyses the views of the UK general public about important aspects of health considered to be missing from the instrument. METHODS: Survey respondents were asked whether there are any aspects of health they consider to be important but are not captured by the EQ-5D, and, if so, what these aspects are...
April 13, 2017: Patient
https://www.readbyqxmd.com/read/28409288/temporary-fusionless-posterior-occipitocervical-fixation-for-a-proximal-junctional-type-ii-odontoid-fracture-after-previous-c2-pelvis-fusion-case-report-description-of-a-new-surgical-technique-and-review-of-the-literature
#20
Alexander A Theologis, Vedat Deviren, Bobby Tay
PURPOSE: Axial fractures in patients with a previous C2-pelvis posterior instrumented fusion are rare and may be challenging to manage. Motion preservation in the axial spine for these patients is important, as the C1-2 and Occipit-C1 joints are their only remaining mobile spinal segments. In this unique report, we present for the first time the use of a fusionless occipitocervical operation for the treatment of a type II odontoid fracture and unilateral C2 pars fracture adjacent to a previous C2-pelvis posterior instrumented fusion...
April 13, 2017: European Spine Journal
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