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https://www.readbyqxmd.com/read/29340780/health-related-quality-of-life-in-outpatients-with-schizophrenia-factors-that-determine-changes-over-time
#1
Cristina Domenech, Carlo Altamura, Corrado Bernasconi, Ricardo Corral, Helio Elkis, Jonathan Evans, Ashok Malla, Marie-Odile Krebs, Anna-Lena Nordstroem, Mathias Zink, Josep Maria Haro
PURPOSE: The objective of this study was to analyze the clinical factors associated with changes in HRQoL in outpatients with schizophrenia using both generic and condition-specific HRQoL scales. METHODS: Adult outpatients with schizophrenia at least 18 years of age who did not have an acute psychotic exacerbation in the 3 months prior to baseline were recruited. PANSS dimensions were calculated based on Lindenmayer et al.'s five factors. HRQoL data were assessed by patients using the Schizophrenia Quality of Life Scale (SQLS), the Short Form-36 (SF-36), and the EuroQol-5 Dimension (EQ-5D) questionnaires...
January 16, 2018: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/29338685/functional-health-state-description-and-valuation-by-people-aged-65-and-over-a-pilot-study
#2
Riaan Botes, Karin M Vermeulen, Adelita V Ranchor, Erik Buskens
BACKGROUND: Assessing quality of life among the elderly is a complex and multifaceted issue. Elderly people might find valuing and describing their personal experience of quality of life (QoL) demanding and cumbersome. This study therefore sought to determine the feasibility of administering two questionnaires in two samples of elderly people. METHODS: A preference-based instrument (EQ-5D + C) and a currently achieved functioning questionnaire (CAF) were utilized...
January 16, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29326818/coping-social-support-and-information-in-patients-with-pulmonary-arterial-hypertension-or-chronic-thromboembolic-pulmonary-hypertension-a-2-year-retrospective-cohort-study
#3
Bodil Ivarsson, Göran Rådegran, Roger Hesselstrand, Barbro Kjellström
Objectives: Pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension are severe diseases with complicated treatment that need care at specialist clinics. The aim was to investigate changes in the patients' perceptions on coping, social support and received information when attending a newly started nurse-coordinated pulmonary arterial hypertension-outpatient clinic. Methods: The present study was a descriptive, questionnaire-based cohort study including 42 adult patients...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29326183/transvaginal-natural-orifice-transluminal-endoscopic-surgery-vnotes-adnexectomy-for-benign-pathology-compared-with-laparoscopic-excision-notable-a-protocol-for-a-randomised-controlled-trial
#4
Jan Filip Baekelandt, Peter A De Mulder, Ilse Le Roy, Chantal Mathieu, Annouschka Laenen, Paul Enzlin, Steven Weyers, Ben W J Mol, Jan J A Bosteels
INTRODUCTION: Natural orifice transluminal endoscopic surgery (NOTES) uses natural orifices to access the cavities of the human body to perform surgical interventions. NOTES limits the magnitude of surgical trauma and potentially reduces postoperative pain. Our group published a protocol on a randomised study comparing transvaginal NOTES (vNOTES) versus laparoscopy for hysterectomy (HALON). We simultaneously designed a similar randomised controlled trial (RCT) comparing vNOTES with laparoscopy for adnexectomy...
January 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29326030/patient-reported-outcomes-following-abiraterone-acetate-plus-prednisone-added-to-androgen-deprivation-therapy-in-patients-with-newly-diagnosed-metastatic-castration-naive-prostate-cancer-latitude-an-international-randomised-phase-3-trial
#5
Kim N Chi, Andrew Protheroe, Alfredo Rodríguez-Antolín, Gaetano Facchini, Henrik Suttman, Nobuaki Matsubara, Zhangqun Ye, Bhumsuk Keam, Ronaldo Damião, Tracy Li, Kelly McQuarrie, Bin Jia, Peter De Porre, Jason Martin, Mary B Todd, Karim Fizazi
BACKGROUND: In the LATITUDE trial, addition of abiraterone acetate plus prednisone to androgen deprivation therapy (ADT) improved overall survival compared with placebos plus ADT in patients with newly diagnosed, high-risk, metastatic castration-naive prostate cancer. Understanding the effects of treatments on patient-reported outcomes (PROs) and health-related quality of life (HRQOL) is important for treatment decisions; therefore we aimed to analyse the effects of ADT plus abiraterone acetate and prednisone versus ADT plus placebos on PROs and HRQOL in patients in the LATITUDE study...
January 8, 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29324334/rivaroxaban-versus-warfarin-for-the-prevention-of-post-thrombotic-syndrome
#6
K K Utne, A Dahm, H S Wik, L P Jelsness-Jørgensen, P M Sandset, W Ghanima
INTRODUCTION: Despite treatment of acute deep vein thrombosis (DVT) with low molecular weight heparin and warfarin, up to 50% of patients develop post-thrombotic syndrome (PTS). Our aims were to assess whether treatment of DVT with rivaroxaban would reduce the rate of subsequent PTS and improve health-related quality of life (HRQoL) as compared to conventional anticoagulation with low molecular weight heparin (LMWH)/warfarin. MATERIALS AND METHODS: Consecutive patients with an objectively confirmed DVT diagnosed between 2011 and 2014 and treated with either rivaroxaban or warfarin were included in this study 24 (±6) months after DVT...
January 8, 2018: Thrombosis Research
https://www.readbyqxmd.com/read/29322966/the-influence-of-adjunctive-caudal-epidural-steroid-injection-on-the-therapeutic-effect-of-transforaminal-epidural-steroid-injection
#7
Atilla Kircelli, Tufan Cansever, Cem Yılmaz
BACKGROUND: Epidural steroid injection is widely used to treat the short and long-term symptoms of low back and radicular pain. To the best of our knowledge, the influence of transforaminal epidural steroid injection (TFSI) combined with caudal epidural steroid injection (CESI) on pain intensity, patient satisfaction, and quality of life in lumbar radiculopathy has not been examined. AIM: To evaluate the short and long-term efficacy of TFSI, and TFSI combined with CESI (TFSI + CESI) in patients with lumbar radiculopathy...
January 2018: Neurology India
https://www.readbyqxmd.com/read/29321017/influence-of-the-child-s-perceived-general-health-on-the-primary-caregiver-s-health-status
#8
Janine Verstraete, Lebogang Ramma, Jennifer Jelsma
BACKGROUND: In estimating the impact of an intervention, ignoring the effect of improving the health of one member of the caregiver/child dyad on the Health Related Quality of Life (HRQoL) of the other member may lead to an underestimation of the utility gained. This may be particularly true for infants/young children and their caregivers. The aim of this study was to quantify the interaction between the child's perceived general health as assessed by the newly developed Toddler and Infant Questionnaire (TANDI) on the reporting of the caregiver's own HRQoL as assessed by the EQ-5D-3 L...
January 10, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29320900/societal-costs-of-multiple-sclerosis-in-ireland
#9
Peter Carney, Derek O'Boyle, Aidan Larkin, Chris McGuigan, Killian O'Rourke
AIMS: This paper evaluates the impact of multiple sclerosis (MS) in Ireland and estimates the associated direct, indirect, and intangible costs to society based on a large nationally representative sample. MATERIALS AND METHODS: A questionnaire was developed to capture the demographics, disease characteristics, healthcare use, informal care, employment, and wellbeing. Referencing international studies, standardised survey instruments were included (e.g., CSRI, MFIS-5, EQ-5D) or adapted (EDSS) for inclusion in an online survey platform...
January 10, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29316832/cost-effectiveness-of-supported-employment-adapted-for-people-with-affective-disorders
#10
Sanjib Saha, Ulrika Bejerholm, Ulf-G Gerdtham, Johan Jarl
OBJECTIVE: The individual enabling and support (IES) model was effective in gaining competitive employment for people with affective disorders compared with traditional vocational rehabilitation (TVR) services in a randomized controlled trial in a Swedish setting. The object of this study is to perform a cost-effectiveness analysis of IES comparing to TVR. METHODS: We considered the costs of intervention and productivity gain due to increased competitive employment...
January 9, 2018: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/29316059/cost-effectiveness-analyses-of-anti-hcv-treatments-using-qol-scoring-among-patients-with-chronic-liver-disease-in-the-hiroshima-prefecture
#11
Terumi Kaishima, Tomoyuki Akita, Masayuki Ohisa, Kazuaki Sakamune, Akemi Kurisu, Aya Sugiyama, Hiroshi Aikata, Kazuaki Cyayama, Junko Tanaka
AIM: We estimated the cost-effectiveness of direct acting antiviral treatment (DAA) compared to triple therapy (simeprevir, pegylated interferon-α and ribavirin) (scenario-1) and Peg-IFN+RBV(scenario-2) and non-antiviral therapy(scenario-3). METHODS: The Cost-effectiveness was evaluated as incremental cost-effectiveness ratios (ICERs) using direct costs and indirect costs which included loss of wages during the patient's lifetime due to early death caused by viral hepatitis infection...
January 5, 2018: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/29316049/evaluation-of-cosmetic-outcome-following-breast-conserving-therapy-in-trials-panel-versus-digitalized-analysis-and-the-role-of-proms
#12
Mirelle Lagendijk, Elvira L Vos, Daan Nieboer, Cornelis Verhoef, Evelien M L Corten, Linetta B Koppert
Cosmetic outcome is an important quality of life-related end point following breast-conserving therapy (BCT). To advise on a gold standard, we compare cosmetic outcome evaluated by panel and an objective evaluation (BCCT.core software). Second, patient-reported outcome measures (PROMs) are compared to cosmetic outcome evaluation by panel and BCCT.core. Sixty-eight breast cancer patients were included following BCT between 2007 and 2012. Two independent 6-member panels and two observers using the BCCT.core evaluated cosmetic outcome...
January 8, 2018: Breast Journal
https://www.readbyqxmd.com/read/29316012/quality-of-life-with-ablation-or-medical-therapy-for-ventricular-arrhythmias-a-substudy-of-vanish
#13
Lorne J Gula, Steve Doucette, Peter Leong-Sit, Anthony S L Tang, Ratika Parkash, Jean-Francois Sarrazin, Bernard Thibault, Vidal Essebag, Stanley K Tung, Marc W Deyell, Jean-Marc Raymond, Chris Lane, Pablo B Nery, George D Veenhuyzen, Damian P Redfearn, Jeffrey S Healey, Jean-Francois Roux, Karen Giddens, John L Sapp
BACKGROUND/OBJECTIVE: We compared health-related quality of life (HRQoL) in patients randomized to escalated-therapy and those randomized to ablation for ventricular tachycardia in the VANISH trial. METHODS: HRQoL was assessed among VANISH patients at baseline and 3-, 6- and 12-month follow-up visits. Four validated instruments were used: the SF-36, the ICD Concerns questionnaire (ICDC), the Hospital Anxiety and Depression Scale (HADS), and the EuroQol five dimensions questionnaire (EQ-5D)...
January 9, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29315466/good-quality-of-life-before-cardiac-arrest-predicts-good-quality-of-life-after-resuscitation
#14
H Hellevuo, M Sainio, H Huhtala, K T Olkkola, J Tenhunen, S Hoppu
BACKGROUND: The survival rate of cardiac arrest patients is increasing. Our aim was to compare the quality of life before and after cardiac arrest and analyse the factors associated with outcome. METHODS: All adult cardiac arrest patients admitted to the Tampere University Hospital intensive care unit between 2009 and 2011 were included in a retrospective follow-up study if surviving to discharge and were asked to return a questionnaire after 6 months. Data on patient demographics and pre-arrest quality of life were retrieved from medical records...
January 7, 2018: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/29312851/evaluation-of-1031-primary-titanium-nitride-coated-mobile-bearing-total-knee-arthroplasties-in-an-orthopedic-clinic
#15
Stefan J M Breugem, Jeroen Linnartz, Inger Sierevelt, Jon D Bruijn, Marcel J M Driessen
AIM: To evaluate the influence of the titanium nitride (TiN) coating on the results of a total knee arthroplasty (TKA). METHODS: A total of 910 patients (338 men; 572 woman), with a mean age of 65 (range 36-94) undergoing 1031 primary TKAs were assessed. Clinical evaluation and patient-reported outcomes were gathered one year after surgery. The questionnaires included the Knee injury and Osteoarthritis Outcome Score (KOOS)-Dutch version, Visual Analogue Scale (VAS) pain scores in rest and during active knee movement, VAS-satisfaction scores, and EQ-5D-3L health scores...
December 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/29310641/health-services-research-in-patients-with-breast-cancer-camiss-prospective-study-protocol-for-an-observational-prospective-study
#16
Susana García-Gutierrez, Miren Orive, Cristina Sarasqueta, Maria Jose Legarreta, Nerea Gonzalez, Maximino Redondo, Amado Rivero, Pedro Serrano-Aguilar, Xavier Castells, Jose Maria Quintana, Maria Sala
BACKGROUND: Though breast cancer remains a major health problem, there is a lack of information on health care provided to patients with this disease and associated costs. In addition, there is a need to update and validate risk stratification tools in Spain. Our purpose is to evaluate the health services provided for breast cancer in Spain, from screening and diagnosis to treatment and prognosis. METHODS: Prospective cohort study involving 13 hospitals in Spain with a follow-up period of up to 5 years after diagnostic biopsy...
January 8, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29307032/cross-cultural-adaptation-and-validation-of-a-patient-reported-hip-outcome-score
#17
Horia Haragus, Radu Prejbeanu, Dan V Poenaru, Bogdan Deleanu, Bogdan Timar, Dinu Vermesan
PURPOSE: We aimed to perform psychometric testing for the translated Oxford Hip Score (OHS) for use as a recommended tool to measure treatment outcomes. METHODS: The original English questionnaire was translated and culturally validated using the instrument developer's guidelines and the ISPOR principles of good practice. One hundred patients completed the form together with the Harris Hip Score (HHS) and EQ-5D-5 L. Fifty patients repeated the form after two days...
January 6, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29305782/an-empirical-comparison-of-the-measurement-properties-of-the-eq-5d-5l-demqol-u-and-demqol-proxy-u-for-older-people-in-residential-care
#18
Tiffany Easton, Rachel Milte, Maria Crotty, Julie Ratcliffe
PURPOSE: This study aimed to empirically compare the measurement properties of self-reported and proxy-reported (in cases of severe cognitive impairment) generic (EQ-5D-5L) and condition-specific (DEMQOL-U and DEMQOL-Proxy-U) preference-based HRQoL instruments in residential care, where the population is characterised by older people with high rates of cognitive impairment, dementia and disability. METHODS: Participants were recruited from seventeen residential care facilities across four Australian states...
January 5, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29305456/wound-irrigation-does-not-affect-health-related-quality-of-life-after-open-fractures-results-of-a-randomized-controlled-trial
#19
S Sprague, B Petrisor, K Jeray, P McKay, D Heels-Ansdell, E Schemitsch, S Liew, G Guyatt, S D Walter, M Bhandari
AIMS: The Fluid Lavage in Open Fracture Wounds (FLOW) trial was a multicentre, blinded, randomized controlled trial that used a 2 × 3 factorial design to evaluate the effect of irrigation solution (soap versus normal saline) and irrigation pressure (very low versus low versus high) on health-related quality of life (HRQL) in patients with open fractures. In this study, we used this dataset to ascertain whether these factors affect whether HRQL returns to pre-injury levels at 12-months post-injury...
January 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29304941/eq-5d-moving-from-three-levels-to-five
#20
EDITORIAL
Andrew Lloyd
No abstract text is available yet for this article.
January 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
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