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Thyroid nodule

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https://www.readbyqxmd.com/read/28213643/ultrasound-guided-fine-needle-aspiration-biopsy-of-thyroid-nodules-in-patients-on-oral-anticoagulants
#1
E Grandone, D Barcellona, D Colaizzo, F Marongiu
No abstract text is available yet for this article.
February 17, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28211803/comparison-of-two-different-2d-shear-wave-speed-imaging-techniques-for-diagnosis-of-thyroid-nodules-the-first-initial-experience
#2
Ya-Ping He, Hui-Xiong Xu, Xiao-Long Li, Dan-Dan Li, Xiao-Wan Bo, Chong-Ke Zhao, Bo-Ji Liu, Dan Wang, Hui-Xiong Xu
OBJECTIVE: The aim of this study was to compare the diagnostic performance of two different 2D shear wave speed imaging techniques of Virtual Touch Tissue Imaging & Quantification (VTIQ) and Toshiba shear wave elastography (T-SWE) in predicting malignant thyroid nodules (TNs). MATERIALS AND METHODS: 75 TNs in 75 patients which were subject to both VTIQ and T-SWE examinations were enrolled and analyzed. Shear wave speed (SWS) values on VTIQ and T-SWE were computed (SWS_max, min, mean and median)...
February 17, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28208864/study-of-immunohistochemical-markers-ck-19-cd-56-ki-67-p53-in-differentiating-benign-and-malignant-solitary-thyroid-nodules-with-special-reference-to-papillary-thyroid-carcinomas
#3
Smriti Sudhanshu Dwivedi, Siddhi Gaurish Sinai Khandeparkar, Avinash R Joshi, Maithili Mandar Kulkarni, Pallavi Bhayekar, Amruta Jadhav, Musphera Nayar, Neelam S Kambale
INTRODUCTION: Solitary Thyroid Nodule (STN) has provoked increased concern owing to higher incidence of malignancy. The inter and intra observer variation in the histomorphological diagnosis of Papillary Thyroid Carcinomas (PTC) may sometimes pose a diagnostic difficulty. AIM: This study was undertaken to analyse immunohistochemical (IHC) markers (CK-19, CD-56, p53, Ki-67) to differentiate between benign and malignant surgically resected STN along with their utility in the identification of PTC...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28204971/the-presence-of-cancerous-nodules-in-lymph-nodes-is-a-novel-indicator-of-distant-metastasis-and-poor-survival-in-patients-with-papillary-thyroid-carcinoma
#4
Ling Chen, Youzhi Zhu, Ke Zheng, Huihao Zhang, Hongkun Guo, Li Zhang, Kunlin Wu, Lingjun Kong, Weihong Ruan, Jianying Hu, Xin Zhang, Xiangjin Chen
PURPOSE: Several characteristics of lymph node metastasis (LNM) as predictors of the risk of recurrence or death were examined in patients with papillary thyroid carcinoma (PTC). The presence of cancerous nodules as a characteristic of LNMs in PTC has not yet been reported. The objective of this study was to evaluate the use of the cancerous nodules in the lymph node (CNLN) to determine the risk of distant metastasis and survival in patients with PTC. METHODS: This retrospective observational cohort study enrolled 1408 patients with pathologically confirmed PTC without initial distant metastasis who underwent thyroidectomy and neck dissection...
February 15, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28203621/comparative-study-evaluating-the-efficiency-of-cooled-and-uncooled-single-treatment-mwa-in-thyroid-nodules-after-a-3-month-follow-up
#5
Oscar Maximilian Mader, Nadine Farivar Tanha, Alexander Mader, Christian Happel, Yücel Korkusuz, Frank Grünwald
OBJECTIVE: The aim of this study was to evaluate and compare the efficacy of single-treatment cooled and uncooled microwave ablation in thyroid nodules. METHODS: Eighteen patients (11 women) with an average age of 62 years (range: 41-80) with 18 cold, mainly solid or solid thyroid nodules were treated with cooled or uncooled microwave ablation. Pain during the treatment was measured on a 10-point score. Side effects revealed by ultrasound or patients' complaints were documented...
2017: European Journal of Radiology Open
https://www.readbyqxmd.com/read/28201927/histologic-findings-and-cytological-alterations-in-thyroid-nodules-after-radioactive-iodine-treatment-for-graves-disease
#6
Siba El Hussein, Yumna Omarzai
Unlike the well-documented relation between radiation to the neck and development of papillary thyroid carcinoma, a causal association between radioactive iodine treatment for Graves' disease and development of thyroid malignancy is less defined. However, patients with a background of thyroid dysfunction presenting with clinically palpable thyroid nodules are followed more closely than the average population, and fine needle aspiration is recommended in such circumstances. Cytological examination of aspirates, and histologic examination of tissue provided from patients with a known history of Graves' disease, managed by radioactive iodine therapy can create a diagnostic dilemma, as the distinction between radiation effect and a malignant primary thyroid neoplasm can be very challenging...
February 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28196954/metformin-and-thyroid-disease
#7
Xianghui Meng, Shuhang Xu, Guofang Chen, Michael Derwahl, Chao Liu
An intriguing area of research in thyroidology is the recently discovered association of insulin resistance with thyroid functional and morphological abnormalities. Individuals with hyperinsulinemia have larger thyroid gland and a higher prevalence of thyroid nodules and cancer. Accordingly, patients treated with metformin have a smaller thyroid volume and a lower risk of incident goiter, thyroid nodule and cancer. Multiple studies in vitro and in vivo have demonstrated that metformin can inhibit the growth of thyroid cells and different types of thyroid cancer cells by affecting the insulin/IGF-1 and mTOR pathways...
February 14, 2017: Journal of Endocrinology
https://www.readbyqxmd.com/read/28194993/preoperative-prediction-of-papillary-thyroid-microcarcinoma-via-multiparameter-ultrasound
#8
Hui Juan Ma, Jing Chun Yang, Zhen Peng Leng, Ying Chang, Hua Kang, Liang Hong Teng
Background Accurate diagnosis of papillary thyroid microcarcinoma (PTMC) is important for further management. Ultrasound (US) is the most frequently used imaging modality for PTMC. Purpose To evaluate the diagnostic value of conventional US, contrast-enhanced ultrasound (CEUS) and real-time elastography (RTE) for patients with PTMC. Material and Methods In total, 135 patients with subcentimeter thyroid nodules who underwent conventional US, CEUS, and RTE before surgery were enrolled. A multivariate logistic regression analysis was performed to assess the independent predictors of PTMC...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28192631/thyroid-cytology-nuclear-versus-architectural-atypia-within-the-atypia-of-undetermined-significance-follicular-lesion-of-undetermined-significance-bethesda-category-have-significantly-different-rates-of-malignancy
#9
Tiffany Rui Xuan Gan, Min En Nga, Jeffrey Huey Yew Lum, Wendy Meihua Wong, Wee Boon Tan, Rajeev Parameswaran, Kee Yuan Ngiam
BACKGROUND: The Bethesda System for Reporting Thyroid Cytopathology is the most widely used classification system for the reporting of thyroid fine-needle aspiration cytology (FNAC) specimens. However, the "atypical" category ("atypia of undetermined significance" [AUS] or "follicular lesion of undetermined significance" [FLUS]) continues to cause diagnostic and therapeutic dilemmas. The objectives of this study were to describe the differential malignancy rates of FNACs diagnosed as AUS/FLUS based on nuclear or architectural atypia and to assess the significance of demographic and ultrasonographic features in predicting malignancy in this category...
February 13, 2017: Cancer
https://www.readbyqxmd.com/read/28191291/diffuse-follicular-variant-of-papillary-thyroid-carcinoma-a-case-report-with-a-revision-of-literature
#10
Gian Luca Rampioni Vinciguerra, Niccolò Noccioli, Armando Bartolazzi
The diffuse follicular variant of papillary thyroid carcinoma (DFV-PTC) is a rare malignant thyroid condition. It represents an uncommon variant of papillary carcinoma characterized by a diffuse involvement of thyroid parenchyma, follicular architecture and nuclear features of PTC in absence of a surrounding capsule. Up to date few data have been collected about this entity and, at the best of our knowledge, only 24 cases have been reported in the literature. According to these reports DFV-PTC seems to occur preferentially in young women and shows more aggressive behavior than other papillary thyroid tumors...
November 17, 2016: Rare Tumors
https://www.readbyqxmd.com/read/28188700/how-suspicious-is-that-nodule-review-of-suspicious-afirma-gene-expression-classifier-in-high-risk-thyroid-nodules
#11
Sudarshana Roychoudhury, Melissa Klein, Fabiola Souza, Cecilia Gimenez, Alice Laser, Rubina Shaheen Cocker, Karen Chau, Kasturi Das
BACKGROUND: The Afirma gene expression classifier (GEC) is being increasingly utilized to confirm the benign nature of indeterminate FNA cytology results thus avoiding unnecessary surgical procedures. However the "suspicious" result of the Afirma GEC does not classify these indeterminate nodules further in determining appropriate management. This study investigated the outcome of the thyroid nodules deemed to be "suspicious" by the Afirma GEC in a high risk population. METHODS: The pathology database was searched for all thyroid nodules with Afirma test results over a three year period, 2013-2015...
February 11, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28186630/cascade-convolutional-neural-networks-for-automatic-detection-of-thyroid-nodules-in-ultrasound-images
#12
Jinlian Ma, Fa Wu, Tian'an Jiang, Jiang Zhu, Dexing Kong
PURPOSE: It is very important for calculation of clinical indices and diagnosis to detect thyroid nodules from ultrasound images. However, this task is a challenge mainly due to heterogeneous thyroid nodules with distinct components are similar to background in ultrasound images. In this study, we employ cascade deep convolutional neural networks (CNNs) to develop and evaluate a fully automatic detection of thyroid nodules from 2D ultrasound images. METHODS: Our cascade CNNs are a type of hybrid model, consisting of two different CNNs and a new splitting method...
February 10, 2017: Medical Physics
https://www.readbyqxmd.com/read/28186108/corrigendum-quality-of-life-and-cost-effectiveness-of-radiofrequency-ablation-versus-open-surgery-for-benign-thyroid-nodules-a-retrospective-cohort-study
#13
Wen-Wen Yue, Shu-Rong Wang, Feng Lu, Xiao-Long Li, Hui-Xiong Xu, Li-Ping Sun, Le-Hang Guo, Ya-Ping He, Dan Wang, Zhi-Qiang Yin
No abstract text is available yet for this article.
February 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28185344/incidental-and-nonincidental-canine-thyroid-tumors-assessed-by-multidetector-row-computed-tomography-a-single-centre-cross-sectional-study-in-4520-dogs
#14
Giovanna Bertolini, Michele Drigo, Luca Angeloni, Marco Caldin
Thyroid nodules are common in dogs and are increasingly likely to be detected with the increased use of advanced imaging modalities. An unsuspected, nonpalpable, asymptomatic lesion, defined as a thyroid incidentaloma, may be discovered on an imaging study unrelated to the thyroid gland. The objective of this single-center cross-sectional study was to assess the prevalence and computed tomography (CT) characteristics of incidental and nonincidental thyroid tumors in a large population of dogs, using prospective recruitment of patients undergoing CT examination for various reasons during the period of 2005-2015...
February 9, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28184253/concordance-between-the-tirads-ultrasound-criteria-and-the-bethesda-cytology-criteria-on-the-nontoxic-thyroid-nodule
#15
Hernando Vargas-Uricoechea, Ivonne Meza-Cabrera, Jorge Herrera-Chaparro
BACKGROUND: Thyroid nodule is a common disorder of the thyroid. Despite their benign nature, they can be associated with multiple pathologic conditions, including thyroid cancer. METHODS: This cross-sectional study determined the concordance of Ultrasound (TIRADS criteria) and Fine Needle Aspiration Biopsy (FNA-BETHESDA system) in the assessment of the nontoxic thyroid nodule. A total of 180 subjects 18 years old or older underwent the two diagnostic tests and their results were compared using kappa index...
2017: Thyroid Research
https://www.readbyqxmd.com/read/28182829/transoral-endoscopic-thyroidectomy-vestibular-approach-toetva-from-a-to-z
#16
Gianlorenzo Dionigi, Matteo Lavazza, Alessandro Bacuzzi, Davide Inversini, Vincenzo Pappalardo, Ralph P Tufano, Hoon Yub Kim, Angkoon Anuwong
We depict the transoral endoscopic thyroidectomy vestibular approach (TOETVA). Patient selection criteria are (1) ultrasonographically (US) estimated thyroid diameter no larger than 10cm, (2) US estimated gland volume ≥45mL, (3) nodule size ≥5mm, (4) a benign tumor, such as a thyroid cyst, single-nodular goiter, or multinodular goiter, (5) follicular neoplasm, and (6) papillary microcarcinoma without evidence of metastasis. TOETVA is carried out through a three-port technique placed at the oral vestibule, one 10mm port for 30° endoscope and two additional 5mm ports for dissecting and coagulating instruments...
February 7, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28182069/role-of-morphometry-in-the-cytological-differentiation-of-benign-and-malignant-thyroid-lesions
#17
Pallavi Khatri, Monisha Choudhury, Manjula Jain, Shaji Thomas
CONTEXT: Thyroid nodules represent a common problem, with an estimated prevalence of 4-7%. Although fine needle aspiration cytology (FNAC) has been accepted as a first line diagnostic test, the rate of false negative reports of malignancy is still high. Nuclear morphometry is the measurement of nuclear parameters by image analysis. Image analysis can merge the advantages of morphologic interpretation with those of quantitative data. AIMS: To evaluate the nuclear morphometric parameters in fine needle aspirates of thyroid lesions and to study its role in differentiating benign from malignant thyroid lesions...
January 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28182068/evaluation-of-thyroid-nodules-classified-as-bethesda-category-iii-on-fnac
#18
Shiwani Garg, Leena P Naik, Kanchan S Kothari, Gwendolyn C Fernandes, Mona A Agnihotri, Jagruti C Gokhale
BACKGROUND: The Bethesda (BSRTC) category III has been ascribed a malignancy rate of 5-15%, however, the probability of malignancy remains variable. AIM: To evaluate category III with respect to its rate and risk of malignancy and substratify it. SETTINGS AND DESIGN: Atypia of undetermined significance/Follicular lesion of undetermined significance (AUS/FLUS) percentage, cytohistological correlation, and risk of malignancy were analyzed and substratification was done...
January 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28182063/frontal-bone-metastasis-from-an-occult-follicular-thyroid-carcinoma-diagnosed-by-fnac
#19
Rajnish Kalra, Richa Pawar, Sonia Hasija, Abha Chandna, Manoj Sankla, Chanchal Malhotra
Metastatic deposits in skull bones from follicular thyroid carcinoma is rare, and metastatic disease in skull being the presenting symptom without obvious thyroid lesion (occult primary) is even rarer. A 60-year-old female patient presented with a mass in the frontal region of the skull. Fine needle aspiration cytology was done which revealed an adenocarcinoma with repeated follicular pattern, reminiscent of follicular neoplasm of thyroid, which on immunocytochemistry revealed positivity for thyroglobulin. Patient was investigated further for primary thyroid malignancy, and imaging revealed a nodule in the left lobe of thyroid...
January 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28181983/incidentally-found-postoperative-spindle-cell-nodule-of-the-breast-6-months-after-ultrasound-guided-vacuum-assisted-excision
#20
Yeo Jin Kim, Mirinae Seo, Yu-Mee Sohn, So Youn Shin
Postoperative spindle cell nodule (PSCN) is a very rare pathologic complication that can occur in association with a recent core needle biopsy, surgery, or trauma. Cases of PSCN have been reported in the lower genitourinary tract, endometrium, and thyroid but are rare in the breast. Herein, we report an ultrasound-guided biopsy-proven PSCN after ultrasound-guided vacuum-assisted excision in the breast.
February 9, 2017: Ultrasound Quarterly
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