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https://www.readbyqxmd.com/read/28748416/cryoprotective-effect-of-resveratrol-on-dna-damage-and-crucial-human-sperm-messenger-rnas-possibly-through-5-amp-activated-protein-kinase-activation
#1
Maryam Shabani Nashtaei, Saeid Nekoonam, Mohammad Naji, Shabnam Bakhshalizadeh, Fardin Amidi
This work aimed at investigating the effect of resveratrol on (1) DNA integrity and (2) fertilizing capacity of sperm by quantifying the presence of key paternal transcripts considered as markers for male fertility (protamine 1 [PRM1] and protamine 2 [PRM2]) and pregnancy success (adducin 1 alpha [ADD1]) in cryopreserved human spermatozoa through modulation of AMP-activated protein kinase (AMPK). The study populations was drawn from 22 normozoospermic healthy volunteers which were incubated with or without AMPK activator (resveratrol [RSV], 15 µM) or inhibitor (Compound C [CC], 30 µM) for 1 h and were then cryopreserved...
July 26, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/28717318/hemogram-responses-in-goats-toward-challenged-with-corynebacterium-pseudotuberculosis-and-its-immunogen-mycolic-acids
#2
Mohammed Naji Odhah, Faez Firdaus Jesse Abdullah, Abd Wahid Haron, Mohd Azmi Mohd Lila, Mohd Zamri-Saad, Zaid Khuder, Idris Umar Hambali, Muhammed Umar, Wessam Monther Saleh
AIM: This study was conducted to analyze the changes in blood profile of goats inoculated with Corynebacterium pseudotuberculosis and its immunogen mycolic acid (MA) extract. MATERIALS AND METHODS: A total of 12 clinically healthy crossbred Boer female goats were divided into three groups; A, B and C (4 goats each per group). Group A was inoculated with 2 ml sterile phosphate buffered saline via intradermal route as the negative control group whilst Group B was inoculated with 2 ml of MA extract (1 g/ml) intradermally and Group C was then inoculated with 2 ml (1×10(9)) colony forming unit of active C...
June 2017: Veterinary World
https://www.readbyqxmd.com/read/28710727/the-occurrence-of-microplastic-contamination-in-littoral-sediments-of-the-persian-gulf-iran
#3
Abolfazl Naji, Zinat Esmaili, Sherri A Mason, A Dick Vethaak
Microplastics (MPs; <5 mm) in aquatic environments are an emerging contaminant of concern due to their possible ecological and biological consequences. This study addresses that MP quantification and morphology to assess the abundance, distribution, and polymer types in littoral surface sediments of the Persian Gulf were performed. A two-step method, with precautions taken to avoid possible airborne contamination, was applied to extract MPs from sediments collected at five sites during low tide. MPs were found in 80% of the samples...
July 14, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28689946/evaluating-the-effectiveness-of-internal-iliac-artery-branched-endovascular-stent-grafts
#4
Faysal Naji, Varun Srivatsav, Mohammed Qadura, John Harlock, Tara Andrinopoulos, Vikram Iyer, Theodore Rapanos
PURPOSE: To describe our institutional experience using iliac branch grafts (IBGs) in aortoiliac aneurysm repair. METHODS: From October 2009 to April 2016, 41 consecutive patients (all men), mean age 71.7 years (range 55-87), underwent IBG implantation. Abdominal aortic aneurysm with common iliac artery involvement (n=21) or bilateral common iliac artery aneurysms (n=20) were indications. Computed tomography was used to evaluate patency and postoperative endoleaks within one month of implantation and after one year...
July 6, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28682729/the-extract-of-lycium-depressum-stocks-enhances-wound-healing-in-streptozotocin-induced-diabetic-rats
#5
Siamak Naji, Leila Zarei, Masoumeh Pourjabali, Rahim Mohammadi
In diabetes, impaired wound healing and other tissue abnormalities are considered major concerns. The aim of the present study was to assess the wound-healing activity of methanolic extracts of the extract of Lycium depressum leaves. A total of 60 healthy male Wistar diabetic rats weighing approximately 160 to 180 g and 7 weeks of age were randomized into 10 groups for incision and excision wound models: sham surgery group (SHAM), including creation of wounds and no treatment; base formulation group (FG) with creation of wounds and application of base formulation ointment; treatment group 1 (TG1) with 1 g of powder extract of the plant material in ointment; treatment group 2 (TG2) with 2 g; and treatment group 4 (TG3) with 4 g of powder extract of the plant material in ointment...
June 2017: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/28667291/a-biomimetic-heparinized-composite-silk-based-vascular-scaffold-with-sustained-antithrombogenicity
#6
Masoud Zamani, Mona Khafaji, Mohammad Naji, Manouchehr Vossoughi, Iran Alemzadeh, Nooshin Haghighipour
Autologous grafts, as the gold standard for vascular bypass procedures, associated with several problems that limit their usability, so tissue engineered vessels have been the subject of an increasing number of works. Nevertheless, gathering all of the desired characteristics of vascular scaffolds in the same construct has been a big challenge for scientists. Herein, a composite silk-based vascular scaffold (CSVS) was proposed to consider all the mechanical, structural and biological requirements of a small-diameter vascular scaffold...
June 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28667163/leukotriene-c4-potentiates-il-33-induced-group-2-innate-lymphoid-cell-activation-and-lung-inflammation
#7
Sean J Lund, Alex Portillo, Kellen Cavagnero, Rachel E Baum, Luay H Naji, Jana H Badrani, Amit Mehta, Michael Croft, David H Broide, Taylor A Doherty
Asthma is a complex disease that is promoted by dysregulated immunity and the presence of many cytokine and lipid mediators. Despite this, there is a paucity of data demonstrating the combined effects of multiple mediators in asthma pathogenesis. Group 2 innate lymphoid cells (ILC2s) have recently been shown to play important roles in the initiation of allergic inflammation; however, it is unclear whether lipid mediators, such as cysteinyl leukotrienes (CysLTs), which are present in asthma, could further amplify the effects of IL-33 on ILC2 activation and lung inflammation...
June 30, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28663189/erratum-national-institutes-of-health-sponsored-clinical-islet-transplantation-consortium-phase-3-trial-manufacture-of-a-complex-cellular-product-at-eight-processing-facilities-diabetes-2016-65-3418-3428
#8
Camillo Ricordi, Julia S Goldstein, A N Balamurugan, Gregory L Szot, Tatsuya Kin, Chengyang Liu, Christine W Czarniecki, Barbara Barbaro, Nancy D Bridges, Jose Cano, William R Clarke, Thomas L Eggerman, Lawrence G Hunsicker, Dixon B Kaufman, Aisha Khan, David-Erick Lafontant, Elina Linetsky, Xunrong Luo, James F Markmann, Ali Naji, Olle Korsgren, Jose Oberholzer, Nicole A Turgeon, Daniel Brandhorst, Andrew S Friberg, Ji Lei, Ling-Jia Wang, Joshua J Wilhelm, Jamie Willits, Xiaomin Zhang, Bernhard J Hering, Andrew M Posselt, Peter G Stock, A M James Shapiro
No abstract text is available yet for this article.
June 29, 2017: Diabetes
https://www.readbyqxmd.com/read/28627931/hyperacoustic-hypoacusis-a-new-pontine-syndrome-case-report
#9
Mohammad Hassan A Noureldine, Raghid Kikano, Naji Riachi, Rechdi Ahdab
We herein report a unique case of a lateral pontine demyelinating lesion presenting with unilateral sensorineural hearing loss and paradoxical ipsilateral hyperacusis. The association of unilateral hearing loss and ipsilateral hyperacusis is a rare manifestation of a central nervous system lesion. The paradoxical combination of these symptoms strongly suggests pontine dysfunction and prompts urgent neurological evaluation.
June 19, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28616420/investigation-effect-of-oral-chamomilla-on-sleep-quality-in-elderly-people-in-isfahan-a-randomized-control-trial
#10
Mehrdad Abdullahzadeh, Pegah Matourypour, Sayed Ali Naji
BACKGROUND: Elderly people often suffer from sleep disorders. Chamomile due to the many health benefits such as sedation may be effective in improving sleep quality in elderly people. This study aimed to determine the effect of Matricaria chamomilla extract on sleep quality in elderly people admitted to nursing homes of Isfahan in 2014. MATERIALS AND METHODS: The present study is a quasi-experimental clinical trial. The study population was 77 cases of elderly hospitalized in nursing homes...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/28600158/lorcaserin-plus-lifestyle-modification-for-weight-loss-maintenance-rationale-and-design-for-a-randomized-controlled-trial
#11
Jena Shaw Tronieri, Nasreen Alfaris, Ariana M Chao, Rebecca L Pearl, Naji Alamuddin, Zayna M Bakizada, Robert I Berkowitz, Thomas A Wadden
BACKGROUND/AIMS: Few studies have examined the efficacy of recently approved medications for chronic weight management in facilitating the maintenance of lost weight. This paper provides an overview of the design and rationale for a trial investigating whether lorcaserin, when combined with behavioral weight loss maintenance sessions (WLM), will facilitate the maintenance of losses of ≥5% of initial weight. METHODS: In this two-phase trial, participants with obesity will enroll in a 14-week run-in diet program consisting of weekly group lifestyle modification sessions and a 1000-1200kcal/d meal replacement diet...
August 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28595075/adsorption-and-photocatalysis-efficiency-of-magnetite-quantum-dots-anchored-tin-dioxide-nanofibers-for-removal-of-mutagenic-compound-toxicity-evaluation-and-antibacterial-activity
#12
Ali Fakhri, Mahsa Naji, Pedram Afshar Nejad
The Magnetite Fe3O4 quantum dots anchored SnO2 nanofibers (Fe3O4 QDs/SnO2 NFs) have been synthesized using the facile one step hydrothermal method. The characteristic structure of synthesized Fe3O4 QDs/SnO2 NFs was analyzed using X-ray diffraction, Transmission electron Microscopy, Scanning electron microscopy, UV-vis diffuse reflectance, photoluminescence spectroscopy, and N2 adsorption-desorption instrumental techniques. The crystallites size of Fe3O4QDs/SnO2 NFs was 7.0nm. The average diameters of Fe3O4QDs/SnO2 NFs were 7...
May 31, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28591015/design-of-studies-for-antibiotic-treatment-of-acute-appendicitis-in-children-in-support-of-rcts
#13
Jan F Svensson, Barbora Patkova, Markus Almström, Hussein Naji, Tomas Wester, Nigel J Hall, Simon Eaton, Agostino Pierro
No abstract text is available yet for this article.
July 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28591013/response-to-letter-is-antibiotic-alternative-to-appendectomy
#14
Jan F Svensson, Barbora Patkova, Markus Almström, Hussein Naji, Nigel J Hall, Simon Eaton, Agostino Pierro, Tomas Wester
No abstract text is available yet for this article.
July 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28584884/population-splitting-of-rodlike-swimmers-in-couette-flow
#15
Hossein Nili, Masoud Kheyri, Javad Abazari, Ali Fahimniya, Ali Naji
We present a quantitative analysis on the response of a dilute active suspension of self-propelled rods (swimmers) in a planar channel subjected to an imposed shear flow. To best capture the salient features of the shear-induced effects, we consider the case of an imposed Couette flow, providing a constant shear rate across the channel. We argue that the steady-state behavior of swimmers can be understood in the light of a population splitting phenomenon, occurring as the shear rate exceeds a certain threshold, initiating the reversal of the swimming direction for a finite fraction of swimmers from down- to upstream or vice versa, depending on the swimmer position within the channel...
June 6, 2017: Soft Matter
https://www.readbyqxmd.com/read/28579787/the-impact-of-comorbid-psychiatric-disorders-on-methadone-maintenance-treatment-in-opioid-use-disorder-a-prospective-cohort-study
#16
Tea Rosic, Leen Naji, Monica Bawor, Brittany B Dennis, Carolyn Plater, David C Marsh, Lehana Thabane, Zainab Samaan
OBJECTIVE: There is a significant interindividual variability in treatment outcomes in methadone maintenance treatment (MMT) for opioid use disorder (OUD). This prospective cohort study examines the impact of comorbid psychiatric disorders on continued illicit opioid use in patients receiving MMT for OUD. METHODS: Data were collected from 935 patients receiving MMT in outpatient clinics between June 2011 and June 2015. Using linear regression analysis, we evaluated the impact of having a comorbid psychiatric disorder on continued illicit opioid use during MMT, adjusting for important confounders...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28574836/hpv-associated-differential-regulation-of-tumor-metabolism-in-oropharyngeal-head-and-neck-cancer
#17
Young-Suk Jung, Abdo J Najy, Wei Huang, Seema Sethi, Michael Snyder, Wael Sakr, Gregory Dyson, Maik Hüttemann, Icksoo Lee, Rouba Ali-Fehmi, Silvia Franceschi, Linda Struijk, Harold E Kim, Ikuko Kato, Hyeong-Reh Choi Kim
HPV-positive oropharyngeal cancer patients experience significantly lower locoregional recurrence and higher overall survival in comparison with HPV-negative patients, especially among those who received radiation therapy. The goal of the present study is to investigate the molecular mechanisms underlying the differential radiation sensitivity between HPV-negative and HPV-positive head and neck squamous cell carcinoma (HNSCC). Here, we show that HPV-negative HNSCC cells exhibit increased glucose metabolism as evidenced by increased production of lactate, while HPV-positive HNSCC cells effectively utilize mitochondrial respiration as evidenced by increased oxygen consumption...
May 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28570706/coplanar-uhf-rfid-tag-antenna-with-u-shaped-inductively-coupled-feed-for-metallic-applications
#18
Karrar Naji Salman, Alyani Ismail, Raja Syamsul Azmir Raja Abdullah, Tale Saeedi
In this paper, we present a novel compact, coplanar, tag antenna design for metallic objects. Electrically small antenna has designed for a UHF RFID (860-960 MHz) based on a proximity-coupled feed through. Furthermore, two symmetrical Via-loaded coplanar grounds fed by a U-shaped inductively coupled feed through an embedded transmission line. This configuration results in an antenna with dimensions of 31 × 19.5 × 3.065 mm3 at 915 MHz, and the total gain for the antenna is 0.12 dBi. The Via-loaded coplanar and U-shaped inductively coupled feeds allow the antenna to provide flexible tuning in terms of antenna impedance...
2017: PloS One
https://www.readbyqxmd.com/read/28564587/effects-of-low-frequency-electrical-stimulation-of-the-anterior-piriform-cortex-on-kainate-induced-seizures-in-rats
#19
Arezou Bayat, Mark D Skopin, Sweta Joshi, Mithilesh Siddu, Loulwah Mukharesh, Sahar Jahan, Komei Tsuchiya, Phillip Connell, Naji Younes, Mohamad Z Koubeissi
OBJECTIVE: Recent evidence in animals and humans suggests that low-frequency stimulation (LFS) has significant antiepileptic properties. The anterior piriform cortex (APC) is a highly susceptible seizure-trigger zone and may be critical for the initiation and propagation of seizures originating from cortical and limbic foci. We used the kainic acid (KA) seizure model in rats to assess the therapeutic effect of LFS of the APC on seizures. METHODS: Adult male Sprague-Dawley rats were implanted with electrodes in the left APC and recording electrodes bilaterally in the hippocampal CA3 regions...
May 28, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28559420/incremental-prognostic-use-of-left-ventricular-global-longitudinal-strain-in-asymptomatic-minimally-symptomatic-patients-with-severe-bioprosthetic-aortic-stenosis-undergoing-redo-aortic-valve-replacement
#20
Peyman Naji, Shailee Shah, Lars G Svensson, A Marc Gillinov, Douglas R Johnston, L Leonardo Rodriguez, Richard A Grimm, Brian P Griffin, Milind Y Desai
BACKGROUND: With improved survival of patients undergoing primary bioprosthetic aortic valve replacement (AVR), reoperation to relieve severe prosthetic aortic stenosis (PAS) is increasing. Timing of redo surgery in asymptomatic/minimally symptomatic patients remains controversial. Left ventricular (LV) global longitudinal strain (GLS) is a marker of subclinical LV dysfunction. In asymptomatic/minimally symptomatic patients with severe PAS undergoing redo AVR, we sought to determine whether LV-GLS provides incremental prognostic use...
June 2017: Circulation. Cardiovascular Imaging
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