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https://www.readbyqxmd.com/read/28966549/myopia-induced-by-flickering-light-in-guinea-pig-eyes-is-associated-with-increased-rather-than-decreased-dopamine-release
#1
Xiumei Luo, Bing Li, Tao Li, Yue Di, Changyue Zheng, Shunmei Ji, Yuanyuan Ma, Jie Zhu, Xuefeng Chen, Xiaodong Zhou
PURPOSE: It is well known that the dopaminergic signaling pathway plays a pivotal role in the control of axial elongation. Much research has shown that retinal dopamine (DA) is decreased in experimental myopia, but the exact alteration in DA quantity underlying the myopia model induced by flickering light (FL) has not yet been fully elucidated. Therefore, in this study, we first attempted to prove the feasibility of the myopia model induced by FL and then to determine whether and how DA and its receptors changed in myopia induced by FL...
2017: Molecular Vision
https://www.readbyqxmd.com/read/28919296/ocular-findings-on-follow-up-in-children-who-received-phototherapy-for-neonatal-jaundice
#2
Semra Kara, Züleyha Yalniz-Akkaya, Ayça Yeniaras, Firdevs Örnek, Yıldız Dallar Bilge
BACKGROUND: To evaluate the ocular findings in children between 3 and 5 years of age who had received phototherapy in the neonatal period and to investigate whether they had phototherapy-related permanent ocular damage clinically. METHODS: The phototherapy group (n = 57) consisted of children who had undergone phototherapy for at least 24 h, and the control group (n = 43) comprised children who had not received phototherapy. Ophthalmic examinations consisted of assessment of visual acuity, convergence near point, ocular movements, ocular alignment, dynamic retinoscopy, cycloplegic refraction and biomicroscopic examination of anterior segment and posterior segment (using a 90 D lens in the latest)...
September 14, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28879667/clinical-biomicroscopy-and-retinoscopy-findings-of-keratoconus-in-a-middle-eastern-population
#3
Mohammad Naderan, Ali Jahanrad, Mahgol Farjadnia
BACKGROUND: The present work was conducted to investigate the prevalence of clinical biomicroscopy and retinoscopy findings of corneas with keratoconus (KC) at first presentation and their relationship with disease severity. METHOD: In a prospective cross-sectional study, 371 consecutive KC patients were examined by slitlamp biomicroscopy and retinoscopy at the time of diagnosis. This research evaluates the prevalence of clinical findings such as a corneal protrusion, Vogt's striae, Fleischer's ring, Munson's sign, Rizzuti's sign, corneal scars, as well as any additional KC signs such as prominent nerve fibres, scissoring reflex and Charleaux 'oil droplet' sign on retinoscopy...
September 6, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28861357/the-evolution-of-refractive-status-in-chinese-infants-during-the-first-year-of-life-and-its-affected-factors
#4
Shu-Juan Yu, Guo-Hua Liu, Yi Liu, Jing Huang, Ming-Lei Han, Bo-Jun Zhao, Zhong-Tao Gai
AIM: To study the evolution of the refractive status and examine the affected factors in infants during the first year of life in a large sample size in China. METHODS: A total of 1258 babies (2516 eyes) aged 32wk gestational age to 1y participated in the study, including 766 premature and 492 full-term infants. First, each baby received an orthoptic examination, slit-lamp checking and fundus imaging. Patients with diseases which might affect refractive status were excluded from the cohort...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28858003/refractive-status-in-nepalese-pre-term-and-full-term-infants-early-in-life
#5
Samir Uprety, Priya Morjaria, Jyoti B Shrestha, Gauri S Shrestha, Safal Khanal
SIGNIFICANCE: This study suggests that pre-term infants, even without retinopathy of prematurity, are at risk for abnormal refractive development and informs the need for close monitoring of refractive error in such infants, regardless of their retinopathy of prematurity status. PURPOSE: The present study aims to investigate the refractive error trend in Nepalese pre-term infants without retinopathy of prematurity (ROP) in the first 6 months of life and explore the association of refractive error with birth weight (BW) and gestational age (GA)...
October 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28845326/results-of-screening-in-schools-for-visually-impaired-children
#6
Pınar Bingöl Kızıltunç, Aysun İdil, Hüban Atilla, Ayşen Topalkara, Cem Alay
OBJECTIVES: The aim of this study was to identify the causes of visual impairment in children attending schools for students with visual impairment and to identify children suitable for treatment and rehabilitation. MATERIALS AND METHODS: All students were examined in our department by a pediatric ophthalmologist and an ophthalmologist experienced in low vision and visual rehabilitation. The children's medical histories were recorded. All children underwent ophthalmological examination including visual acuity measurement, anterior segment and dilated fundus evaluation, retinoscopy with cycloplegia, and intraocular pressure measurement...
August 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28746323/ocular-morbidity-among-children-of-government-schools-of-kathmandu-valley-a-follow-up-study
#7
R K Shrestha, G S Shrestha
INTRODUCTION: Ocular and vision defects are common among school going children. Vision disorders, especially refractive errors are the main disabilities of children and the leading cause of handicapping conditions of childhood. The present study was conducted to find out ocular morbidity among students of government schools of Kathmandu valley. METHODS: In the descriptive and cross-sectional study, 2412 students, comprising of 1114 (46.2%) males and 1298 (53.8%) females were enrolled in to the study from the five government schools of Kathmandu valley from 2012 to 2013...
April 2017: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/28676992/topographic-typology-in-a-consecutive-series-of-refractive-surgery-candidates
#8
Seyed-Farzad Mohammadi, Vahid Mohammadzadeh, Sakineh Kadivar, Amir-Houshang Beheshtnejad, Amir Hossein Norooznezhad, Seyed-Hassan Hashemi
PURPOSE: The term 'keratoconus (KC) suspect' is used as a blanket term to refer to any deviation of virgin cornea shape toward KC features. We intend to subclassify such topographies in meaningful and informative designations. METHODS: Pentacam corneal topographies of 199 consecutive refractive surgery candidates (398 eyes) are examined. Features of steepness, inferior-superior asymmetry, focal steepening, thinning, and bounded anterior or posterior elevations are observed in the quad map...
July 4, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28606071/the-increasing-prevalence-of-myopia-in-junior-high-school-students-in-the-haidian-district-of-beijing-china-a-10-year-population-based-survey
#9
MULTICENTER STUDY
Yan Li, Jia Liu, Pengcheng Qi
BACKGROUND: Myopia is a leading cause of preventable blindness. Although, multiple cross-sectional epidemiological studies have confirmed that there is a high prevalence of myopia in high school-aged students in China. However, few longitudinal studies have been performed to assess junior high school students. In the present study, we investigate changes in the prevalence of myopia in third year junior high school (grade 9) students in the Haidian District of Beijing, China, from 2006 to 2015...
June 12, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28569566/ocular-biometry-and-determinants-of-refractive-error-in-a-founder-population-of-european-ancestry
#10
Sarah M Hilkert, Reut Parness-Yossifon, Rebecca Mets-Halgrimson, Marilyn B Mets
BACKGROUND: The prevalence of myopia is increasing worldwide. Previous studies have found a positive association between myopia, education, and near activities, while others have noted a negative association with outdoor exposure. This study reports refractive error and biometry in a founder population of European ancestry, the Hutterites, and discusses risk factors contributing to myopia. METHODS: Cross-sectional study, including complete eye exams with retinoscopy and biometry...
June 1, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/28515427/pediatric-vision-screening-using-the-plusoptix-a12c-photoscreener-in-chinese-preschool-children-aged-3-to-4-years
#11
Dan Huang, Xuejuan Chen, Xiaohan Zhang, Yue Wang, Hui Zhu, Hui Ding, Jing Bai, Ji Chen, Zhujun Fu, Zijin Wang, Hu Liu
This study evaluated the performance of plusoptiX A12C in detecting amblyopia risk factors (ARFs) in Chinese children aged 3-to-4-year. PlusoptiX examination was successfully conducted among 1,766 subjects without cycloplegia to detect refractive error, asymmetry and media opacity. Cycloplegic retinoscopy (CR) was conducted on 357 children suspected of having vision abnormalities. Statistical differences between CR and the device were confirmed using the mean spherical value (+1.41 ± 0.87 D versus +1.14 ± 0...
May 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28510771/inability-of-open-field-autorefraction-to-eliminate-accommodation-in-preschoolers
#12
Caner Kara, İkbal Seza Petriçli
PURPOSE: To evaluate the effectiveness of the Shin-Nippon NVision-K 5001 autorefractometer (Rexxam Co. Ltd., Osaka, Japan) (also branded as the Grand Seiko WR-5100K; Grand Seiko Co. Ltd., Hiroshima, Japan) based on the open-field refractometry principle in refractive measurements of preschool children and to determine its ability to eliminate accommodation adequately. METHODS: The refractive results of 114 preschool children who presented to the ophthalmology outpatient department for screening were evaluated...
September 1, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28471102/cycloplegic-refraction-in-hyperopic-children-effectiveness-of-a-0-5-tropicamide-and-0-5-phenylephrine-addition-to-1-cyclopentolate-regimen
#13
Seul Gi Yoo, Myung Jin Cho, Ungsoo Samuel Kim, Seung Hee Baek
PURPOSE: To evaluate the effectiveness of a cycloplegic regimen using 0.5% tropicamide and 0.5% phenylephrine (Tropherine, Hanmi Pharm), in addition to 1% cyclopentolate, in hyperopic children. METHODS: The medical records of hyperopic patients below the age of 14 years who had undergone cycloplegic retinoscopy were retrospectively reviewed. Cycloplegic refractions were performed using one of two cycloplegic regimens. Regimen 1 was a Tropherine-added regimen comprising the administration of one drop of 1% cyclopentolate followed by two to three drops of Tropherine added at 15-minute intervals...
June 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28390411/prediction-accuracy-of-intraocular-lens-power-calculation-methods-after-laser-refractive-surgery
#14
Yubo Wu, Songyu Liu, Rongfeng Liao
BACKGROUND: This study aimed to evaluate the prediction accuracy of postoperative refractions using partial coherence interferometry (IOL-Master) and applanation ultrasound (AL-3000) assisted with corneal topography (TMS-4) in eyes that had undergone myopic laser-assisted in situ keratomileusis (LASIK). METHODS: Haigis-L formula, Koch-Maloney method using Haigis formula, Shammas clinically derived K-value (simulated keratometric value) correction (Shammas c.d.) using Haigis formula, and Shammas post-LASIK (Shammas-PL) formula were used in eyes with myopic LASIK...
April 8, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28332896/the-distribution-of-macular-thickness-and-its-determinants-in-a-healthy-population
#15
Hassan Hashemi, Mehdi Khabazkhoob, AbbasAli Yekta, Mohammad Hassan Emamian, Payam Nabovati, Akbar Fotouhi
PURPOSE: To determine the distribution of macular thickness in a healthy Iranian population aged 45-69 years and its association with certain determinants. METHODS: All participants underwent optometric examinations including measurement of uncorrected and corrected visual acuity, objective refraction by retinoscopy, and subjective refraction. Subsequently, all participants underwent slit-lamp biomicroscopy followed by fundus examination through direct and indirect ophthalmoscopy, and optical coherence tomography (OCT) imaging under pupil dilation...
March 23, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28251078/vasoactive-intestinal-peptide-a-promising-agent-for-myopia
#16
Ayse Idil Cakmak, Hikmet Basmak, Huseyin Gursoy, Mete Ozkurt, Nilgun Yildirim, Nilufer Erkasap, Mustafa Deger Bilgec, Nese Tuncel, Ertugrul Colak
AIM: To investigate the role of vasoactive intestinal peptide (VIP) in form-deprivation myopia (FDM). METHODS: FDM was created in three groups of eight chicks by placing a translucent diffuser on their right eyes. Intravitreal injections of saline and VIP were applied once a day into the occluded eyes of groups 2 and 3, respectively. Retinoscopy and axial length (AL) measurements were performed on the first and 8(th) days of diffuser wear. The retina mRNA levels of the VIP receptors and the ZENK protein in right eyes of the three groups and left eyes of the first group on day 8 were determined using real time polymerase chain reaction (PCR)...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28060058/corneal-collagen-cross-linking-for-keratoconus-in-pediatric-patients-long-term-results
#17
Prema Padmanabhan, Sudhir Rachapalle Reddi, Rama Rajagopal, Radhika Natarajan, Geetha Iyer, Bhaskar Srinivasan, Niveditha Narayanan, Meena Lakshmipathy, Shweta Agarwal
PURPOSE: To report the long-term outcome of corneal collagen cross-linking (CXL) for progressive keratoconus in pediatric patients. METHODS: "Epithelium-off" CXL was performed in pediatric eyes with progressive keratoconus. Spectacle-corrected distance visual acuity (CDVA), retinoscopy, topography, and tomography were documented preoperatively and postoperatively at 3 months, 6 months, 1 year, and annually thereafter. RESULTS: A total of 377 eyes of 336 pediatric patients aged 8 to 18 years with progressive keratoconus underwent CXL...
February 2017: Cornea
https://www.readbyqxmd.com/read/28032802/risk-factors-for-developing-myopia-among-schoolchildren-in-yerevan-and-gegharkunik-province-armenia
#18
Aida Giloyan, Tsovinar Harutyunyan, Varduhi Petrosyan
PURPOSE: Myopia is a complex condition leading to visual impairment and blindness. This study assessed the prevalence of and risk factors for myopia among schoolchildren in urban and rural areas of Armenia. METHODS: A cross-sectional interviewer-administered survey together with eye screenings was conducted among schoolchildren in the capital Yerevan and in Gegharkunik Province. The study used multi-stage random sampling to obtain the sample of 1260 schoolchildren...
April 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28030881/intra-and-inter-examiner-repeatability-of-cycloplegic-retinoscopy-among-young-children
#19
Sara J McCullough, Lesley Doyle, Kathryn J Saunders
PURPOSE: To evaluate the intra- and inter-examiner repeatability of cycloplegic retinoscopy in young children aged 4-5 years old. METHODS: Examiner 1 refracted all children in the first sample (n = 108); firstly with masked loose lenses, then using unmasked loose lenses (intra-examiner repeatability). Examiners 1 and 2 refracted all children in the second sample (n = 97) using unmasked loose lenses, blind to the child's refractive error, presence/magnitude of habitual spectacle correction and to each other's findings (inter-examiner repeatability)...
January 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28001106/evaluation-of-potential-risk-factors-for-development-of-primary-angle-closure-glaucoma-in-bouviers-des-flandres
#20
Alexis J Dubin, Ellison Bentley, Kevin A Buhr, Paul E Miller
OBJECTIVE To evaluate potential risk factors for development of primary angle-closure glaucoma (PACG) in Bouviers des Flandres. DESIGN Prospective, observational study. ANIMALS 98 Bouviers des Flandres. PROCEDURES All dogs underwent slit-lamp biomicroscopy, indirect ophthalmoscopy, gonioscopy, applanation tonometry, streak retinoscopy, and A-scan, B-scan, and high-resolution ultrasonography. Iridocorneal angles and degree of pectinate ligament dysplasia sheeting were graded, and an angle index was mathematically derived for each eye on the basis of these values...
January 1, 2017: Journal of the American Veterinary Medical Association
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