keyword
https://read.qxmd.com/read/38437939/construction-of-nanoparticles-from-blueberry-anthocyanins-lecithin-gum-arabic-improves-lipid-droplet-accumulation-and-gut-microbiota-disturbance-in-hfd-induced-obese-mice
#21
JOURNAL ARTICLE
Zhen Cheng, Wenwen Wei, Yi Chen, Aihua Xu, Yuehua Wang, Bin Li
The digestive instability of anthocyanins (ACNs) limits their application in food nutrition, especially precision nutrition. Blueberry ACNs-loaded nanoparticles (Lipo/GA-ACNs NPs) were prepared using gum arabic (GA) as the delivery carrier and liposomal vesicles (Lipo) prepared from soy lecithin as the targeting scaffold. The average particle size of the NPs was 99.4 nm, and the polydispersion index (PDI) was 0.46. The results showed that the presence of the Lipo-GA matrix enhanced the NPs' in vitro stability and antioxidant activity...
March 2, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38436807/prep-uptake-and-methamphetamine-use-patterns-in-a-4-year-u-s-national-prospective-cohort-study-of-sexual-and-gender-minority-people-2017-2022
#22
JOURNAL ARTICLE
Yan Guo, Drew A Westmoreland, Alexa B D'Angelo, Chloe Mirzayi, Michelle Dearolf, Meredith Ray, Pedro B Carneiro, David W Pantalone, Adam W Carrico, Viraj V Patel, Sarit A Golub, Sabina Hirshfield, Donald R Hoover, Denis Nash, Christian Grov
Methamphetamine use is on the rise among sexual and gender minority people who have sex with men (SGMSM), escalating their HIV risk. Despite pre-exposure prophylaxis (PrEP) being an effective biomedical HIV prevention tool, its uptake in relation to methamphetamine use patterns in SGMSM has not been studied. In a U.S. cohort study from 2017 to 2022, 6,253 HIV-negative SGMSM indicated for but not using PrEP were followed for four years. Methamphetamine use was categorized (i.e., newly initiated, persistently used, never used, used but quit), and PrEP uptake assessed using generalized estimating equation (GEE), adjusted for attrition...
March 4, 2024: AIDS and Behavior
https://read.qxmd.com/read/38430770/effect-of-an-innovative-sorbent-material-coupled-to-continuous-flow-process-in-the-protein-and-oxidative-stability-of-white-wines
#23
JOURNAL ARTICLE
Arianna Ricci, Andrea Versari, Luigi Ragni, Giuseppina P Parpinello
In this work the impact of an innovative protein stabilization method (TiO2 -based composite sorbent material coupled with a prototype device operating under continuous flow) has been tested in terms of protein and oxidative stability of white wines. Optimal process parameters (duration 60 min; flow rate 1.5 ± 0.1 L/h in 6 cycle rates/h) ensured an average 32.5 % reduction of total proteins; the nanoporous TiO2 film supported on inert glass beads acted as selective sorbent for pathogenesis-related proteins (PRPs, 10-60 kDa) responsible for wine instability, based on the protein stability studies (heat-test) performed in the experimental wines...
February 27, 2024: Food Chemistry
https://read.qxmd.com/read/38428086/protein-aggregation-caused-by-pasteurization-processing-affects-the-foam-performance-of-liquid-egg-white
#24
JOURNAL ARTICLE
Xiang Fan, Qi Wang, Haobo Jin, Yuanyuan Zhang, Yaqin Yang, Zhe Li, Guofeng Jin, Long Sheng
Pasteurization is necessary during the production of liquid egg whites (LEW), but the thermal effects in pasteurization could cause an unavoidable loss of foaming properties of LEW. This study intended to investigate the mechanism of pasteurization processing affects the foam performance of LEW. The foaming capacity (FC) of LEW deteriorated significantly (ΔFCmax = 72.33 %) and foaming stability (FS) increased slightly (ΔFSmax = 3.64 %) under different temperature-time combinations of pasteurization conditions (P < 0...
February 28, 2024: Food Chemistry
https://read.qxmd.com/read/38427387/associations-between-affect-dynamics-and-eating-regulation-in-daily-life-a-preliminary-ecological-momentary-assessment-study
#25
JOURNAL ARTICLE
Alexandro Smith, Kathleen A Page, Kathryn E Smith
Disordered eating behaviors consistently associated with emotion regulation difficulties. However, most studies have focused on affect intensity without considering dynamic affective patterns. We examined these patterns in relation to daily overeating, loss of control eating (LOCE), dietary restraint, and food craving in young adults using ecological momentary assessment (EMA).Adults (N = 24) completed a 10-day EMA protocol during which they reported momentary affect and eating patterns. Generalized linear mixed-models examined each index in relation to eating variable...
March 1, 2024: Cognition & Emotion
https://read.qxmd.com/read/38421255/the-intersectionality-of-food-insecurity-job-insecurity-healthcare-insecurity-and-mental-health-challenges-in-nyc-households-during-covid-19
#26
JOURNAL ARTICLE
Preety Gadhoke, Barrett P Brenton, Saloumeh Sadeghzadeh, Sammy Y Huang, Liam Lane, David Mathieu, Tashnim Rafa, Xavier Albano, Gabriela Noble
Our intersectional research explored food insecurity and job insecurity as predictors of healthcare insecurity and mental health challenges among households living in economic instability since the COVID19 pandemic began. The New York City COVID19 Research Team adapted a validated, web based, anonymous survey questionnaire using a Social Determinants of Health Framework. The study oversampled underserved populations with a total of 2,099 participants. We report strong associations between food insecurity and job insecurity among healthcare insecure households, and significant mental health challenges among food insecure and healthcare insecure households...
February 29, 2024: Ecology of Food and Nutrition
https://read.qxmd.com/read/38417282/structural-characteristics-and-stability-analysis-of-coconut-oil-body-and-its-application-for-loading-%C3%AE-carotene
#27
JOURNAL ARTICLE
Yan Tian, Xinxin Zhao, Zhiguo Wang, Weimin Zhang, Zhiguo Jiang
In this work, we investigated structural characteristics and stability analysis of the coconut oil body (COB) and its application for loading β-carotene (β-CA). The COB contained neutral lipids (81.1 ± 2.1 %), membrane proteins (0.6 ± 0.0 %), and moistures (18.3 ± 3.2 %), in which the molecular weights of membrane proteins ranged from 12 kDa to 40 kDa, as analyzed by the SDS-PAGE. The COB exhibited a small droplet diameter (5...
February 23, 2024: Food Chemistry
https://read.qxmd.com/read/38414240/return-of-polygenic-risk-scores-in-research-stakeholders-views-on-the-emerge-iv-study
#28
JOURNAL ARTICLE
Maya Sabatello, Suzanne Bakken, Wendy K Chung, Elizabeth Cohn, Katherine D Crew, Krzysztof Kiryluk, Rita Kukafka, Chunhua Weng, Paul S Appelbaum
Research on polygenic risk scores (PRS) for common, genetically complex chronic diseases aims to improve health-related predictions, tailor risk-reducing interventions, and improve health outcomes. Yet, the study and use of PRS in clinical settings raise equity, clinical, and regulatory challenges that can be greater for individuals from historically marginalized racial, ethnic, and other minoritized communities. As part of the NHGRI-funded Electronic Medical Records and Genomics (eMERGE) IV Network, we conducted online focus groups with patients/community members, clinicians, and members of Institutional Review Boards (IRBs) to explore their views on key issues, including PRS research, return of PRS results, clinical translation, and barriers and facilitators to health behavioral changes in response to PRS results...
February 26, 2024: HGG advances
https://read.qxmd.com/read/38412567/inhibitory-effects-of-nobiletin-mediated-interfacial-instability-of-bile-salt-emulsified-oil-droplets-on-lipid-digestion
#29
JOURNAL ARTICLE
Xingran Kou, Min Hong, Fei Pan, Xin Huang, Qingran Meng, Yunchong Zhang, Qinfei Ke
Previous lipase inhibitors studies mainly focus on the binding between inhibitors and lipase, ignoring the impact of inhibitors on the oil-water interface of lipid droplets. This study aimed to investigate the effect of nobiletin (NBT) from Citri Reticulatae Pericarpium on the oil-water interface properties and lipid digestion. Here, we found that NBT could destroy bile salt (BS)-stabilized lipid droplets and thus inhibited free fatty acid release, owing to the interaction between NBT and BS at the oil-water interface, and reducing the stability of the oil-water interface (the stability index decreased from 91...
February 17, 2024: Food Chemistry
https://read.qxmd.com/read/38408157/hydrogen-bond-mediated-self-shielded-moisture-responsive-structural-color-for-time-temperature-indicating
#30
JOURNAL ARTICLE
Donghui Kou, Lei Gao, Ruicheng Lin, Shufen Zhang, Wei Ma
Effective monitoring of the time-temperature history of biological reagents, chemical drugs, and perishable foods during cold chain storage is crucial for ensuring their quality and efficacy. Time-temperature indicators (TTIs) are developed to assess the cumulative impact of time and temperature on product quality. However, current indicators face challenges related to complex wrapping procedures, narrow tracking ranges, susceptibility to photobleaching, and pre-use instability, hampering widespread use. Herein, the first moisture-responsive 1D photonic crystal (1DPC) TTIs featuring robust structural colors, customizable time-temperature ranges, and reliable renewability are demonstrated...
February 26, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/38398820/magnesium-and-the-hallmarks-of-aging
#31
REVIEW
Ligia J Dominguez, Nicola Veronese, Mario Barbagallo
Magnesium is an essential ion in the human body that regulates numerous physiological and pathological processes. Magnesium deficiency is very common in old age. Age-related chronic diseases and the aging process itself are frequently associated with low-grade chronic inflammation, called 'inflammaging'. Because chronic magnesium insufficiency has been linked to excessive generation of inflammatory markers and free radicals, inducing a chronic inflammatory state, we formerly hypothesized that magnesium inadequacy may be considered among the intermediaries helping us explain the link between inflammaging and aging-associated diseases...
February 9, 2024: Nutrients
https://read.qxmd.com/read/38397581/unpacking-the-global-rice-trade-network-centrality-structural-holes-and-the-nexus-of-food-insecurity
#32
JOURNAL ARTICLE
Junjie Li, Qin Xiao, Haixia Wu, Jianping Li
The challenging international landscape and exacerbated extreme weather conditions contribute to the instability of global grain trade, complicating its impact on food security. This complexity is particularly pronounced for varieties like rice, which are heavily affected by policy-driven trade restrictions. There is insufficient research on how a country's rice trade characteristics affect food security. A network analysis approach is adopted to intricately dissect the structural characteristics of rice trade...
February 16, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38397572/ultrasensitive-ochratoxin-a-detection-in-cereal-products-using-a-fluorescent-aptasensor-based-on-recj-f-exonuclease-assisted-target-recycling
#33
JOURNAL ARTICLE
Yanxuan Li, Furong Shao, Jin Wu, Mingzhu Liu, Gaofang Cao, Zunquan Zhao, Jialei Bai, Zhixian Gao
Ochratoxin A (OTA) is a mycotoxin widely found in foodstuffs such as cereal grains. It greatly threatens human health owing to its strong toxicity and high stability. Aptasensors have emerged as promising tools for the analysis of small molecule contaminants. Nucleic-acid-based signal amplification enables detectable signals to be obtained from aptasensors. However, this strategy often requires the use of complex primers or multiple enzymes, entailing problems such as complex system instability. Herein, we propose a fluorescent aptasensor for the ultrasensitive detection of OTA in cereal products, with signal amplification through RecJf exonuclease-assisted target recycling...
February 16, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38396961/analysis-of-the-model-of-atherosclerosis-formation-in-pig-hearts-as-a-result-of-impaired-activity-of-dna-repair-enzymes
#34
JOURNAL ARTICLE
Robert Paslawski, Paweł Kowalczyk, Urszula Paslawska, Jerzy Wiśniewski, Piotr Dzięgiel, Adrian Janiszewski, Liliana Kiczak, Maciej Zacharski, Barbara Gawdzik, Karol Kramkowski, Andrzej Szuba
Excessive consumption of food rich in saturated fatty acids and carbohydrates can lead to metabolic disturbances and cardiovascular disease. Hyperlipidemia is a significant risk factor for acute cardiac events due to its association with oxidative stress. This leads to arterial wall remodeling, including an increase in the thickness of the intima media complex (IMT), and endothelial dysfunction leading to plaque formation. The decreased nitric oxide synthesis and accumulation of lipids in the wall result in a reduction in the vasodilating potential of the vessel...
February 14, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38394186/household-food-insecurity-is-associated-with-greater-autonomic-dysfunction-testing-score-in-latinos-with-type-2-diabetes
#35
JOURNAL ARTICLE
Angela Bermúdez-Millán, Richard Feinn, Rachel Lampert, Rafael Pérez-Escamilla, Sofia Segura-Pérez, Julie Wagner
AIM: We examined household food insecurity (HFI) and autonomic nervous system (ANS) function in a subset of low-income Latinos with type 2 diabetes with data from a stress management trial. METHODS: InclusionLatino or Hispanic, Spanish speaking, age less than 18 years, ambulatory status, type 2 diabetes more than 6 months, A1c less than 7.0%. ExclusionPain or dysfunction in hands (e.g., arthritis) precluding handgrip testing; medical or psychiatric instability. HFI was assessed with the 6-item U...
2024: PloS One
https://read.qxmd.com/read/38380684/talc-and-calcium-carbonate-inclusions-in-direct-expanded-pea-starch-extrudates-exhibit-different-behavior-under-increasing-screw-speeds
#36
JOURNAL ARTICLE
Marina Ikuse, Jana K Richter, Girish M Ganjyal
The ability to modulate direct expanded product structures improves the versatility and range of product applications. The effect of nucleating agents, namely, talc and calcium carbonate (CC), on the expansion characteristics of pea starch extrudates as impacted by screw speed was explored. Pea starch blends with increasing levels of nucleating agents (0.25%, 1%, and 2%) at 18% moisture (w.b.) were extruded across a range of screw speeds (150, 250, 350, and 450 rpm). The water absorption index, water solubility index (WSI), expansion ratio (ER), unit density, and cell count were determined to evaluate the performance of nucleating agents...
February 21, 2024: Journal of Food Science
https://read.qxmd.com/read/38380066/body-size-and-trophic-structure-explain-global-asymmetric-response-of-tetrapod-diversity-to-climate-effects
#37
JOURNAL ARTICLE
Reginaldo A F Gusmão, Geiziane Tessarolo, Ricardo Dobrovolski, Thiago Gonçalves-Souza
Although climate-based hypotheses are widely used to explain large-scale diversity patterns, they fall short of explaining the spatial variation among taxonomic groups. Integrating food web and metabolic theories into macroecology is a promising step forward, as they allow including explicit taxon-specific traits that can potentially mediate the relationship between climate and diversity. Our investigation focuses on the role of body size and trophic structure in mediating the influence of contemporary climate and historical climate change on global tetrapods species richness...
February 2024: Ecology and Evolution
https://read.qxmd.com/read/38376842/food-insecurity-among-graduate-students-and-postdoctoral-trainees
#38
JOURNAL ARTICLE
Nour M Hammad, Cindy W Leung
IMPORTANCE: Food insecurity on college campuses has emerged as an urgent public health priority; however, there has been a lack of studies focused on graduate students or postdoctoral trainees, particularly those enrolled at private academic institutions. OBJECTIVE: To estimate the prevalence of and factors associated with food insecurity among graduate students and postdoctoral trainees at a private academic university in Boston, Massachusetts. DESIGN, SETTING, AND PARTICIPANTS: In this cross-sectional survey study, a survey on food insecurity was sent to graduate students and postdoctoral trainees at 3 health-focused graduate schools at Harvard University during the end of the spring 2023 academic term (April to June)...
February 5, 2024: JAMA Network Open
https://read.qxmd.com/read/38370060/preserving-nutrient-content-in-red-cabbage-juice-powder-via-foam-mat-hybrid-microwave-drying-application-in-fortified-functional-pancakes
#39
JOURNAL ARTICLE
Muhammed Mustafa Ozcelik, Sedef Aydin, Ebru Aydin, Gulcan Ozkan
Red cabbage, a highly nutritious cool-season cruciferous vegetable, is rich in anthocyanins; however, the instability of anthocyanins during processing and storage poses challenges. This study aimed to optimize the foam-mat drying process of red cabbage juice (RCJ) with a high anthocyanin content using a hybrid microwave hot air-drying system (MW-HAD) as a dehydration method compared to conventional techniques (HAD) using response surface methodology (RSM). Additionally, the produced red cabbage juice powder (RCJP) was used to enrich the pancake formulation...
February 2024: Food Science & Nutrition
https://read.qxmd.com/read/38361351/sotatercept-for-pulmonary-arterial-hypertension-in-the-inpatient-setting
#40
REVIEW
Heather Torbic, Adriano R Tonelli
Patients with pulmonary arterial hypertension (PAH) who are admitted to the hospital pose a challenge to the multidisciplinary healthcare team due to the complexity of the pathophysiology of their disease state and PAH-specific medication considerations. Pulmonary arterial hypertension is a progressive disease that may lead to death as a result of right ventricular (RV) failure. During acute on chronic RV failure it is critical to decrease the pulmonary vascular resistance with the goal of improving RV function and prognosis; therefore, aggressive PAH-treatment based on disease risk stratification is essential...
2024: Journal of Cardiovascular Pharmacology and Therapeutics
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