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https://www.readbyqxmd.com/read/29040256/the-role-of-genomics-in-patients-with-advanced-prostate-cancer
#1
Maha H Hussain
No abstract text is available yet for this article.
October 2017: Clinical Advances in Hematology & Oncology: H&O
https://www.readbyqxmd.com/read/29033726/ultrasound-guided-multilevel-paravertebral-block-versus-local-anesthesia-for-medical-thoracoscopy
#2
Maha A Abo-Zeid, Mohammad M Elgamal, Asem A Hewidy, Amro A Moawad, Alaa Eldin Adel Elmaddawy
BACKGROUND: Local anesthetic infiltration for medical thoracoscopy has an analgesic properties for short duration. Single injection thoracic paravertebral block (PVB) provides limited analgesia. PURPOSE: Comparison between thoracic PVB performed at two or three levels with local infiltration for anesthetic adequacy in adult medical thoracoscopy as a primary outcome and postthoracoscopic analgesia and pulmonary function as secondary outcomes for adult medical thoracoscopy...
October 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/29033725/assessment-of-patient-controlled-analgesia-versus-intermittent-opioid-therapy-to-manage-sickle-cell-disease-vaso-occlusive-crisis-in-adult-patients
#3
Alaa Al-Anazi, Lowloa Al-Swaidan, Maha Al-Ammari, Tariq Al-Debasi, Abdulmalik M Alkatheri, Shmeylan Al-Harbi, Aiman A Obaidat, Abdulkareem M Al-Bekairy
BACKGROUND: Vaso-occlusive crisis (VOC) is one of the acute complications of sickle-cell disease (SCD). Treatment mainly relies on hydration and pain control by analgesics. The specific aim of this study was to assess potential health outcomes within the first 72 h of admission between intermittent and patient-controlled analgesia (PCA) by opioids among VOC patients. METHODS: A retrospective chart review study was conducted to determine SCD patients with VOC. Using the hospital electronic system, the following data were collected: patient's age, gender, blood pressure, heart rate, respiratory rate, oxygen saturation, and pain score on admission and daily for 3 days as well as the cumulative opioid analgesic dose for 72 h which is reported as morphine equivalent...
October 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/29028812/occurrence-of-the-middle-east-respiratory-syndrome-coronavirus-mers-cov-across-the-gulf-corporation-council-countries-four-years-update
#4
Mahmoud Aly, Mohamed Elrobh, Maha Alzayer, Sameera Aljuhani, Hanan Balkhy
The emergence of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections has become a global issue of dire concerns. MERS-CoV infections have been identified in many countries all over the world whereas high level occurrences have been documented in the Middle East and Korea. MERS-CoV is mainly spreading across the geographical region of the Middle East, especially in the Arabian Peninsula, while some imported sporadic cases were reported from the Europe, North America, Africa, and lately Asia...
2017: PloS One
https://www.readbyqxmd.com/read/29028160/angiotensin-converting-enzyme-insertion-deletion-gene-polymorphism-in-egyptian-children-with-cap-a-case-control-study
#5
Heba Abouzeid, Usama M Alkholy, Mohammed A Abdou, Saeed M Morsy, Hind M Abdelrahman, Ashraf M Sherif, Nermin Abdalmonem, Mohammed E Hamed, Mayy A N Allah, Salah Al Morshedy, Shaimaa S A Elashkar, Maha A Noah, Mohamed S Hegab, Nagwa E Akeel, Mustafa I A Hashem, Heba H Gawish, Lobna Abdel Fattah
BACKGROUND: Community-acquired pneumonia (CAP) is a major cause of childhood morbidity and mortality worldwide. The angiotensin-converting enzyme (ACE) gene is a potential candidate gene for CAP risk. OBJECTIVES: In this study, we aimed to investigate whether the ACE insertion/deletion (I/D) polymorphism (rs4340) could be a genetic marker for CAP susceptibility in Egyptian children, and we also measured the serum ACE level to assess its relation to such polymorphism...
October 13, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29020851/impact-of-attending-the-diwaniyyah-on-kuwaiti-men-s-health
#6
Maha Al-Sejari
Diwaniyyah is a traditional gathering place for men in the Arab world. Most Kuwaiti men spend most of their time in the diwaniyyah, which is an important part of their social activity. The current study aims to examine the relationship between the diwaniyyah as a social community and the attendees' health conditions to determine how the diwaniyyah affects Kuwaiti men's lifestyle. A questionnaire was distributed among 500 men 16 years old and above. It comprised five parts of data: sociodemographic information, frequency of attending diwaniyyah, types of diwaniyyahs, and health lifestyle of members attending the diwaniyyah...
October 1, 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/29019333/evaluation-of-brca1-large-genomic-rearrangements-in-group-of-egyptian-female-breast-cancer-patients-using-mlpa
#7
Ola M Eid, Eman A El Ghoroury, Maha M Eid, Rana M Mahrous, Mohamed I Abdelhamid, Zahra I Aboafya, Esmat A Abdel Ghaffar, Amany H Abdelrahman
INTRODUCTION: Breast cancer is one of the most widespread cancers affecting women all over the world. In Egypt, it is considered to be the first cause of malignancies among female. BRCA1 Large Genomic Rearrangements (LGRs) have been reported in hereditary breast families and occurs in considerable proportion of cases in various populations. OBJECTIVE AND METHODS: We investigated the incidence of BRCA1 LGRs in group of Egyptian females with breast cancer using Multiplex Ligation-dependent Probe Amplification (MLPA) assay...
September 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29018476/recurrent-and-prolonged-infections-in-a-child-with-a-homozygous-ifih1-nonsense-mutation
#8
Maha Zaki, Michaela Thoenes, Amit Kawalia, Peter Nürnberg, Rolf Kaiser, Raoul Heller, Hanno J Bolz
In an Egyptian girl born to consanguineous parents, whole-exome sequencing (WES) identified a homozygous mutation in PHGDH, c.1273G>A (p.Val425Met), indicating 3-phosphoglycerate dehydrogenase deficiency. This diagnosis was compatible with the patient's microcephaly, severe psychomotor retardation, seizures and cataracts. However, she additionally suffered from recurrent (at least monthly) episodes of prolonged and severe chest infections requiring hospitalization, suggesting a secondary, predisposing and potentially Mendelian, condition...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/29017503/effect-of-bacterial-lipase-on-anaerobic-co-digestion-of-slaughterhouse-wastewater-and-grease-in-batch-condition-and-continuous-fixed-bed-reactor
#9
Maha Affes, Fathi Aloui, Fatma Hadrich, Slim Loukil, Sami Sayadi
BACKGROUND: This study aimed to investigate the effects of bacterial lipase on biogas production of anaerobic co-digestion of slaughterhouse wastewater (SHWW) and hydrolyzed grease (HG). A neutrophilic Staphylococcus xylosus strain exhibiting lipolytic activity was used to perform microbial hydrolysis pretreatment of poultry slaughterhouse lipid rich waste. RESULTS: Optimum proportion of hydrolyzed grease was evaluated by determining biochemical methane potential...
October 10, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29017248/fluoroquinolone-resistance-mutation-detection-is-equivalent-to-culture-based-drug-sensitivity-testing-for-predicting-multidrug-resistant-tuberculosis-treatment-outcome-a-retrospective-cohort-study
#10
Maha R Farhat, Karen R Jacobson, Molly F Franke, Devinder Kaur, Megan Murray, Carole D Mitnick
Background: Molecular diagnostics that rapidly and accurately predict fluoroquinolone (FQ) resistance promise to improve treatment outcomes for individuals with multidrug-resistant (MDR) tuberculosis (TB). Mutations in the gyr genes, though, can cause variable levels of in vitro FQ resistance, and some in vitro resistance remains unexplained by gyr mutations alone, but the implications of these discrepancies for treatment outcome are unknown. Methods: We performed a retrospective cohort study of 172 subjects with MDR/extensively drug-resistant TB subjects and sequenced the full gyrA and gyrB open reading frames in their respective sputum TB isolates...
October 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28991511/prevalence-of-congenital-ocular-anomalies-among-children-with-genetic-disorders-an-egyptian-study
#11
Reham H Tomairek, Maha M Amin, Karima Raafat, Sawsan Abdel Hady, Ahmed Elkotoury
PURPOSE: To assess the pattern and frequency of occurrence of ocular anomalies among other genetic disorders in Egypt. METHODS: This is a cross-sectional study of 2500 cases presenting with genetic disorders. Cases were recruited from the clinical genetics department of the National Research Centre (NRC) over a four-year period between January 2011 and December 2014. Ophthalmological examination of the cases was performed in the pediatric ophthalmology department of Cairo University Hospitals...
October 9, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28990245/effects-of-exposure-to-six-chemical-ultraviolet-filters-commonly-used-in-personal-care-products-on-motility-of-mcf-7-and-mda-mb-231-human-breast-cancer-cells-in-vitro
#12
Maha Alamer, Philippa D Darbre
Benzophenone (BP)-1, BP-2, BP-3, octylmethoxycinnamate (OMC), 4-methylbenzilidenecamphor and homosalate are added to personal care products to absorb ultraviolet light. Their presence in human milk and their oestrogenic activity suggests a potential to influence breast cancer development. As metastatic tumour spread is the main cause of breast cancer mortality, we have investigated the effects of these compounds on migration and invasion of human breast cancer cell lines. Increased motility of oestrogen-responsive MCF-7 human breast cancer cells was observed after long-term exposure (>20 weeks) to each of the six compounds at ≥10(-7)  m concentrations using three independent assay systems (scratch assay, live cell imaging, xCELLigence technology) and increased invasive activity was observed through matrigel using the xCELLigence system...
October 9, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/28989525/factors-influencing-compliance-to-the-infection-control-precautions-among-nurses-and-physicians-in-jordan-a-cross-sectional-study
#13
Maysa Nofal, Maha Subih, Mahmoud Al-Kalaldeh
BACKGROUND: Adherence to infection control precautions (ICP) is important to reduce the transmission of healthcare-associated infections (HAIs). AIMS: To determine nurses and physician's knowledge, attitude and compliance to ICPs and factors associated with reported compliance. METHODS: A cross-sectional survey of nurses and physicians recruited from three hospitals at three different healthcare sectors in Jordan. Three instruments were used to assess knowledge, attitudes and compliance to ICPs...
July 2017: Journal of Infection Prevention
https://www.readbyqxmd.com/read/28985412/validated-chromatographic-methods-for-the-simultaneous-determination-of-sulfacetamide-sodium-and-prednisolone-acetate-in-their-ophthalmic-suspension
#14
Nariman A El-Ragehy, Maha A Hegazy, G AbdElHamid, Samia A Tawfik
Two specific, sensitive, rapid and accurate chromatographic methods have been developed, optimized and validated for the simultaneous determination of sulfacetamide sodium and prednisolone acetate in pure forms and in their binary mixture. The first method is an isocratic Reversed phase-high performance liquid chromatography method where a rapid separation was achieved on a Zorbax ODS column using a green mobile phase of methanol: water (80:20, v/v) and pH adjusted to 5.0 ± 0.2 with orthophosphoric acid. The retention times (tR) were 2...
August 2, 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/28984660/selective-scalp-nerve-block-a-useful-technique-with-tissue-expansion-in-postburn-pediatric-alopecia
#15
Maha Ahmed Abo-Zeid, Alaa Eldin Adel Elmaddawy, Mohamed Hassan El-Fahar, Ahmed Hassan El-Sabbagh
BACKGROUND: Scalp defects can be reconstructed either with skin graft, local flaps, free flaps, or tissue expansion. Tissue expanders have been proved to be fruitful in the pediatric population. Scalp expansion has proved to be useful in the reconstruction of posttraumatic and postburn alopecic defects. Selective nerve block can be added for attenuation of sympathetic stimulation and decrease surgical stress in cranial surgeries. In this study, a comparison was done between using selective nerve block and without selective nerve block in both stages of tissue expansion procedure...
October 3, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28983738/establishing-clinical-severity-for-promis-%C3%A2-measures-in-adult-patients-with-rheumatic-diseases
#16
Vivek Nagaraja, Constance Mara, Puja P Khanna, Rajaie Namas, Amber Young, David A Fox, Timothy Laing, William J McCune, Carol Dodge, Debra Rizzo, Maha Almackenzie, Dinesh Khanna
PURPOSE: Different patient-reported outcome (PRO) measures are used for rheumatic diseases (RD). The aims of this study are-(1) Identify PROMIS(®) domains most relevant to care of patients with RD, (2) Collect T-Score metrics in patients with RD, and (3) Identify clinically meaningful cut-points for these domains. METHODS: A convenience sample of RD patients was recruited consecutively during clinic visits, and asked to complete computer-adaptive tests on thirteen Patient-Reported Outcomes Measurement Information System (PROMIS(®)) instruments...
October 5, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28983177/asymptomatic-interventricular-septal-dissection-and-giant-coronary-artery-aneurysms-simulating-cardiac-cysts-multi-modality-imaging
#17
Iliyasse Asfalou, Najat Mouine, Maha Raissouni, Mohammed Sabry, Aatif Benyass
we report an exceptionnel case of asymptomatic interventricular septal dissection and giant coronary artery aneurysms simulating cardiac cysts with a focus in the interst of Multi-modality Imaging.
October 2017: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/28983173/huge-left-atrial-appendage-aneurysm-revealed-by-chronic-hiccups
#18
Iliyasse Asfalou, Meriem Boumaaz, Maha Raissouni, Mohammed Sabry, Aatif Benyass, El Mehdi Zbir
Left atrial appendage (LAA) aneurysm is an extremely rare anomaly. So far, less than one hundred cases only have been reported worldwide. Revelation modes are dominated by complications such as arrhythmias and thromboembolic events. We herein report a pediatric case of huge congenital LAA aneurysm with an original revelation mode that has never been described before in medical literature.
October 2017: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/28983011/complete-genomic-sequence-of-dengue-virus-serotype-4-isolated-from-plasma-collected-from-a-haitian-child-in-2014
#19
Maha A Elbadry, Sarah K White, Julia C Loeb, Massimiliano S Tagliamonte, Marco Salemi, Valery Madsen Beau De Rochars, Taina Telisma, Mohammed Rashid, J Glenn Morris, John A Lednicky
While data are limited, there is increasing evidence that infections by dengue viruses are endemic in Haiti. In 2014, an outbreak caused by dengue virus 4 (DENV-4) followed a chikungunya fever outbreak. We present here the complete genome sequence of one isolate grouped within the genotype II South America and Caribbean DENV-4 clades.
October 5, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28982301/low-malignancy-rates-in-fine-needle-aspiration-cytologies-in-a-primary-care-setting-in-germany
#20
Markus Eszlinger, Maha Ullmann, Ilka Ruschenburg, Katharina Böhme, Fabian Görke, Christiane Franzius, Sabine Adam, Thomas Molwitz, Christian Landvogt, Bassam Amro, Anja Hach, Berit Feldmann, Dieter Graf, Antje E Wefer, Rainer Niemann, Catharina Bullmann, Günther Klaushenke, Reinhard Santen, Gregor Tönshoff, Velimir Ivancevic, Andreas Kögler, Eberhard Bell, Bernd Lorenz, Gerald Kluge, Christoph Hartenstein, Ralf Paschke
BACKGROUND: Reported results for thyroid nodule fine needle aspiration (FNA) cytology mainly originate from tertiary centers. However, thyroid nodule FNA cytology is mainly performed in primary care settings for which the distribution of FNA Bethesda categories and their respective malignancy rates are largely unknown. Therefore, this study investigated FNA cytology malignancy rates of a large primary care setting to determine to what extent current evidence based strategies for the malignancy risk stratification of thyroid nodules are applied and applicable in such primary care settings...
October 6, 2017: Thyroid: Official Journal of the American Thyroid Association
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