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https://www.readbyqxmd.com/read/29684827/differential-responses-of-two-egyptian-barley-hordeum-vulgare-l-cultivars-to-salt-stress
#1
Hayam I A Elsawy, Ahmad Mohammad M Mekawy, Mahmoud A Elhity, Sherif M Abdel-Dayem, Maha Nagy Abdelaziz, Dekoum V M Assaha, Akihiro Ueda, Hirofumi Saneoka
Although barley (Hordeum vulgare L.) is considered a salt tolerant crop species, productivity of barley is affected differently by ionic, osmotic, and oxidative stresses resulting from a salty rhizosphere. The current study was conducted to elucidate the mechanism of salt tolerance in two barley cultivars, Giza128 and Giza126. The two cultivars were exposed to 200 mM NaCl hydroponically for 12 days. Although both cultivars accumulated a large amount of Na+ in their leaves with similar concentrations, the growth of Giza128 was much better than that of Giza126, as measured by maintaining a higher dry weight, relative growth rate, leaf area, and plant height...
April 12, 2018: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29681084/identification-of-a-novel-homozygous-alx4-mutation-in-two-unrelated-patients-with-frontonasal-dysplasia-type-2
#2
Mona El-Ruby, Alaa El-Din Fayez, Sara H El-Dessouky, Mona S Aglan, Inas Mazen, Nora Ismail, Hanan H Afifi, Maha M Eid, Mostafa I Mostafa, Mennat I Mehrez, Yasmin Khalil, Maha S Zaki, Khaled R Gaber, Mohamed S Abdel-Hamid, Ghada M H Abdel-Salam
We report two unrelated boys with frontonasal dysplasias type-2 (FND-2) who shared an identical novel homozygous ALX4 mutation c.291delG (p.Q98Sfs*83). Both patients presented with a large skull defect but one had bilateral parietal meningocele-like cysts that lie along with the bony defect and increased in size with age. Scalp alopecia, hypertelorism, and clefted alae nasi were also detected in both of them. Furthermore, impalpable gonads were noted, being unilateral in one and bilateral in the other. Neuroimaging showed small dysplastic occipital lobes with dysgyria and midline subarachnoid cyst...
May 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29676665/an-ecological-exploration-of-facilitators-to-participation-in-a-mosque-based-physical-activity-program-for-south-asian-muslim-women
#3
Munira Abdulwasi, Meena Bhardwaj, Yuka Nakamura, Maha Zawi, Jennifer Price, Paula Harvey, Ananya Tina Banerjee
BACKGROUND: This descriptive qualitative study informed by an ecological framework explored factors influencing South Asian Muslim women's decisions to participate in a mosque-based physical activity intervention. METHODS: Individual, face-to-face, semistructured interviews were conducted in English, Hindi, or Urdu with 12 South Asian Muslim women at their home or mosque in Ontario, Canada. All interviews were audio-recorded, transcribed verbatim and managed, sorted, and analyzed for themes through a process of descriptive analysis...
April 20, 2018: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/29675563/trans-epithelial-corneal-collagen-cross-linking-with-iontophoresis-for-progressive-keratoconus
#4
Mohammed Ali Abu Ameerh, Muawyah Dawoud Al Bdour, Maha Al-Till, Muhannad Al Faouri
PURPOSE: To evaluate the efficacy of trans-epithelial corneal collagen cross-linking (CXL) with Iontophoresis among patients with progressive keratoconus. METHODS: It is a prospective interventional study, which is based on 41 eyes of 23 patients, suffering from progressive keratoconus and treated with trans-epithelial corneal cross-linking, using iontophoresis with ETDA and trometamol-enriched riboflavin 5 phosphates 0.1% hypotonic solution (Ricrolin+, Soot Italia SpA, Italy)...
April 19, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29674675/pathogen-derived-extracellular-vesicles-mediate-virulence-in-the-fatal-human-pathogen-cryptococcus-gattii
#5
Ewa Bielska, Marta Arch Sisquella, Maha Aldeieg, Charlotte Birch, Eloise J O'Donoghue, Robin C May
The Pacific Northwest outbreak of cryptococcosis, caused by a near-clonal lineage of the fungal pathogen Cryptococcus gattii, represents the most significant cluster of life-threatening fungal infections in otherwise healthy human hosts currently known. The outbreak lineage has a remarkable ability to grow rapidly within human white blood cells, using a unique 'division of labour' mechanism within the pathogen population, where some cells adopt a dormant behaviour to support the growth of neighbouring cells...
April 19, 2018: Nature Communications
https://www.readbyqxmd.com/read/29673997/breast-lesion-shape-and-margin-evaluation-bi-rads-based-metrics-understate-radiologists-actual-levels-of-agreement
#6
Mohammad Rawashdeh, Sarah Lewis, Maha Zaitoun, Patrick Brennan
BACKGROUND: While there is much literature describing the radiologic detection of breast cancer, there are limited data available on the agreement between experts when delineating and classifying breast lesions. The aim of this work is to measure the level of agreement between expert radiologists when delineating and classifying breast lesions as demonstrated through Breast Imaging Reporting and Data System (BI-RADS) and quantitative shape metrics. METHODS: Forty mammographic images, each containing a single lesion, were presented to nine expert breast radiologists using a high specification interactive digital drawing tablet with stylus...
April 13, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29671837/analysis-of-17-genes-detects-mutations-in-81-of-811-patients-with-lissencephaly
#7
Nataliya Di Donato, Andrew E Timms, Kimberly A Aldinger, Ghayda M Mirzaa, James T Bennett, Sarah Collins, Carissa Olds, Davide Mei, Sara Chiari, Gemma Carvill, Candace T Myers, Jean-Baptiste Rivière, Maha S Zaki, Joseph G Gleeson, Andreas Rump, Valerio Conti, Elena Parrini, M Elizabeth Ross, David H Ledbetter, Renzo Guerrini, William B Dobyns
PurposeTo estimate diagnostic yield and genotype-phenotype correlations in a cohort of 811 patients with lissencephaly or subcortical band heterotopia.MethodsWe collected DNA from 756 children with lissencephaly over 30 years. Many were tested for deletion 17p13.3 and mutations of LIS1, DCX, and ARX, but few other genes. Among those tested, 216 remained unsolved and were tested by a targeted panel of 17 genes (ACTB, ACTG1, ARX, CRADD, DCX, LIS1, TUBA1A, TUBA8, TUBB2B, TUBB, TUBB3, TUBG1, KIF2A, KIF5C, DYNC1H1, RELN, and VLDLR) or by whole-exome sequencing...
April 19, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29670833/interaction-of-coenzyme-q10-with-liposomes-and-its-impact-on-suppression-of-selenite-induced-experimental-cataract
#8
Medhat Wahba Shafaa, Amany Hasan Elshazly, Amira Zaki Dakrory, Maha Reda Elsyed
Purpose: To stress the influence of Coenzyme Q10 (CoQ10) on the structural properties of liposomes as model membranes and to investigate the possible role of CoQ10 or CoQ10 doped in liposomes when topically instilled as eye drops, in preventing cataract. Methods: The molecular interaction between liposomes and Coenzyme Q10 was examined using differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FTIR). Rat pups were randomly divided into six groups comprising 15 pups. Group (1), control group...
March 2018: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/29670716/knowledge-attitude-and-practice-of-hepatitis-b-virus-infection-among-dental-students-and-interns-in-saudi-arabia
#9
Hashem-Motahir Al-Shamiri, Fadyah-Eid AlShalawi, Tahani-Mohammed AlJumah, Maha-Mohammad AlHarthi, Esraa-Mohammed AlAli, Hanan-Mohammed AlHarthi
Background: Hepatitis B virus (HBV) is a worldwide healthcare problem. Dental health care professionals are at a high risk of infection by HBV. The present study investigated the knowledge, attitude and practice of HBV infection among Saudi dental students and Interns in Saudi Arabia. Material and Methods: This was a questionnaire-based cross-sectional study. A self-administered questionnaire consisting of questions on students' knowledge, attitudes, and practices regarding HBV was used...
January 2018: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29669898/multi-omics-analysis-of-thermal-stress-response-in-a-zooxanthellate-cnidarian-reveals-the-importance-of-associating-with-thermotolerant-symbionts
#10
Maha J Cziesielski, Yi Jin Liew, Guoxin Cui, Sebastian Schmidt-Roach, Sara Campana, Claudius Marondedze, Manuel Aranda
Corals and their endosymbiotic dinoflagellates of the genus Symbiodinium have a fragile relationship that breaks down under heat stress, an event known as bleaching. However, many coral species have adapted to high temperature environments such as the Red Sea (RS). To investigate mechanisms underlying temperature adaptation in zooxanthellate cnidarians we compared transcriptome- and proteome-wide heat stress response (24 h at 32°C) of three strains of the model organism Aiptasia pallida from regions with differing temperature profiles; North Carolina (CC7), Hawaii (H2) and the RS...
April 25, 2018: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29669330/diabetes-self-management-a-key-for-better-health-related-quality-of-life-in-patients-with-diabetes
#11
Hanan E Badr, Maha Al-Khaledi, Hussah Al-Dousari, Shaikhah Al-Dhufairi, Taiba Al-Mousawi, Rehab Al-Azemi, Farah Al-Azimi
OBJECTIVE: This study was aimed at assessing health-related quality of life (HRQOL) among adult patients with diabetes attending primary health care diabetes clinics in Kuwait and to examine the factors associated with patients with the HRQOL of patients with diabetes. METHODS: This cross-sectional study was conducted among 503 patients with diabetes attending 26 primary healthcare diabetes clinics in Kuwait. A self-administered questionnaire on participants' socio-demographic and clinical characteristics, in addition to the Diabetes Self-Management Questionnaire (DSMQ) to assess patients' DSM was used...
April 17, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29666704/practice-patterns-and-barriers-for-intravenous-thrombolysis-a-survey-of-neurologists-in-saudi-arabia
#12
Mohammed H Alanazy, Rima B Barakeh, Alanood Asiri, Maha F Edrees, Ahmad R Abuzinadah, Bandar N Aljafen, Taim Muayqil
Only a small fraction of patients with acute ischemic stroke receive intravenous thrombolysis (IVT). We sought to assess barriers and practice patterns in using IVT for acute ischemic stroke among neurologists in Saudi Arabia. An electronic survey was sent to all neurologists registered with the Saudi Commission for Health Specialties. A total of 148 (77.5%) neurologists responded. The most common reported barriers for IVT administration were delayed presentation to hospitals (82.4%) and unclear time of symptom onset (50...
2018: Neurology Research International
https://www.readbyqxmd.com/read/29663891/flipped-learning-can-rheumatology-lead-the-shift-in-medical-education
#13
Yasser El Miedany, Maha El Gaafary, Nadia El Aroussy, Sally Youssef
OBJECTIVE: To: 1. implement flipped classroom rheumatology teaching for undergraduate education. 2. Evaluate outcomes of teaching using OSCE assessment and student perceived effectiveness and satisfaction survey. METHODS: The flipped classroom education was conducted in 3 phases. Phase 1: carried out in the students' own time. Web links were emailed to assist exposure of the instructional part of the lesson online. Phase 2: interactive in-class activity to share personal reflection and reinforce the key aspects...
April 16, 2018: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/29658513/b-2-adrenergic-receptor-gene-polymorphism-effect-on-childhood-asthma-severity-and-response-to-treatment
#14
Ashgan Abdallah Alghobashy, Sahar A Elsharawy, Usama M Alkholy, Nermin Abdalmonem, Mohamed Ali Abdou, Maha A A Basset, Heba Fouad Pasha
BackgroundAlterations of B2 adrenergic receptor (β2 AR) can modulate the severity of asthma and the response to treatment. Therefore, we aimed to evaluate β2 AR gene polymorphism at codons 16 and 27 and their effect on asthma severity and response to treatment in asthmatic children.MethodsCase-control study was conducted on 156 children; 104 of them had bronchial asthma and 52 were healthy children (control group). Subjects of the study underwent history taking, clinical examination, pulmonary function tests, serum IgE level assessment, and identification of β2 AR-16 A46G and β2 AR-27 C79G polymorphism using PCR-Restriction Fragment length polymorphisms (RFLP) test...
March 2018: Pediatric Research
https://www.readbyqxmd.com/read/29657195/evaluation-of-serum-soluble-urokinase-plasminogen-activator-receptor-as-a-marker-for-steroid-responsiveness-in-children-with-primary-nephrotic-syndrome
#15
Suzan O Mousa, Salah M Saleh, Hend M Aly, Maha H Amin
Nephrotic syndrome (NS) is the most common primary glomerular disease among children. It runs a relapsing course involving prolonged periods of treatment with corticosteroids and other immunosuppressive medications. Soluble urokinase plasminogen activator receptor (suPAR) has been regarded as an inflammatory as well as a permeability factor. The aim of our study was to evaluate serum suPAR levels in children with NS and its relation to steroid responsiveness. Our study was carried out on 75 children who were already diagnosed as having NS; they were classified into three groups (steroid sensitive, steroid dependent, and steroid resistant)...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29653170/ascorbic-acid-prevents-cellular-uptake-and-improves-biocompatibility-of-chitosan-nanoparticles
#16
Hisham A Elshoky, Taher A Salaheldin, Maha A Ali, Mohamed H Gaber
Chitosan nanoparticles have many applications, such as gene and drug delivery, due to their biocompatibility. Chitosan nanoparticles are currently produced by dissolution in acetic acid that affects the biocompatibility at acidic pH. Here, we synthesized and characterized chitosan (CS) and ascorbate chitosan (AsCS) nanoparticles and investigated their cytotoxic effects, internalization, and distribution in the human colon carcinoma cell line using confocal laser scanning microscopy (CLSM). The CS and AsCS nanoparticles were spherical with average particle sizes of 44 ± 8...
April 10, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29652177/broncho-epithelial-iga-secretion-is-impaired-in-asthma-role-of-il-4-il-13
#17
Maha Zohra Ladjemi, Delphine Gras, Sébastien Dupasquier, Bruno Detry, Marylène Lecocq, Céline Garulli, Chantal Fregimilicka, Caroline Bouzin, Sophie Gohy, Pascal Chanez, Charles Pilette
RATIONALE: Asthma is associated with increased lung IgE production, but whether the secretory (S-)IgA system is affected in this disease remains unknown. OBJECTIVES: We explored mucosal IgA transport in human asthma and its potential regulation by Th2 inflammation. METHODS: Bronchial biopsies from asthma and control subjects were assayed for broncho-epithelial pIgR expression and correlated to Th2 biomarkers. Bronchial epithelium reconstituted in vitro from these subjects, upon culture in air-liquid interface, was assayed for pIgR expression and regulation by IL-4/IL-13...
April 13, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29651430/biochemistry-production-of-high-added-value-biomolecules-for-industrial-uses
#18
EDITORIAL
Maha Karra-Chaabouni, Mohamed Trigui, María M Yust, Mireille K Awad, Pedro J García-Moreno
No abstract text is available yet for this article.
2018: BioMed Research International
https://www.readbyqxmd.com/read/29642944/concomitant-visceral-and-localized-cutaneous-leishmaniasis-in-two-moroccan-infants
#19
Tarik Mouttaki, Hasnaa Maksouri, Jilali El Mabrouki, Gema Merino-Espinosa, Hassan Fellah, Mohamed Itri, Joaquina Martin-Sanchez, Maha Soussi-Abdallaoui, Soumiya Chiheb, Myriam Riyad
BACKGROUND: Leishmaniases are vector-borne diseases caused by the protozoa of the Leishmania genus. The clinical spectrum of these diseases extends from benign dermal lesions to visceral forms. In the Mediterranean region, zoonotic visceral leishmaniasis (ZVL) is caused by L. infantum. If untreated within two years, the disease usually leads to death. In Morocco, ZVL is endemic in the north, with a hundred cases notified each year, mostly in children aged below five years. Here, we report on two clinical observations in infants presenting unusual concomitant VL and cutaneous leishmaniasis (CL) in Morocco...
April 12, 2018: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29628869/palliative-surgical-gastrostomy-under-ultrasound-guided-bilateral-rectus-sheath-blocks-in-a-head-and-neck-cancer-patient
#20
Saima Rashid, Faisal Shamim, Maha Khan, Robyna Khan
No abstract text is available yet for this article.
April 2018: Saudi Journal of Anaesthesia
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