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https://www.readbyqxmd.com/read/28822892/angiolymphoid-hyperplasia-with-eosinophilia-involving-the-common-digital-artery-of-the-hand-a-case-report-and-classification-of-upper-limb-lesions
#1
Mohammad M Al-Qattan, Maha Arafah, Felwa Al-Marshad
INTRODUCTION: Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare benign reactive inflammatory lesion. The usual presentation is a single or multiple skin nodules of the head and neck. Involvement of the hand is very rare and there have been no comprehensive reviews on ALHE of the upper limb. In this paper, we report on a case involving the common digital artery of the hand. We also review the literature and offer two classification systems for upper limb lesions: One according to the primary structure involved, and the other according to the presentation with either single or multiple lesions...
August 10, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28819537/-nod2-gene-mutation-in-moroccan-patients-with-crohn-s-disease-prevalence-genotypic-study-and-correlation-of-nod2-gene-mutation-with-the-phenotype-of-crohn-s-disease
#2
Mouna Tamzaourte, Ikram Errabih, Hayat Krami, Fadlouallah Maha, Lahmiri Maria, Nadia Benzzoubeir, Laaziza Ouazzani, Ahmed Sefiani, Houria Ouazzani
The aim of this study was to determine the prevalence of NOD2/CARD15 gene mutations in a group of Moroccan patients with Crohn's disease and to study its correlation with genotype-phenotypic expression. We conducted a cross-sectional case-control study over a period of 16 months. 101 patients with Crohn's disease were enrolled between January 2012 and April 2013 as well as a control group of 107 patients. We performed a genetic analysis to identify 3 NOD2 gene variants: p.Arg702Trp, p.Gly908Arg and p.Leu1007fsins...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28814955/characterization-of-carbapenem-resistant-acinetobacter-baumannii-strains-isolated-from-hospitalized-patients-in-palestine
#3
Regeen Handal, Lulu Qunibi, Ibrahim Sahouri, Maha Juhari, Rula Dawodi, Hiyam Marzouqa, Musa Hindiyeh
The American Centers for Disease Control and Prevention (CDC) recognizes Acinetobacter baumannii as a source of global outbreaks and epidemics especially due to its increasing resistance to commercially available antibiotics. In this study, 69 single patient multidrug resistant isolates collected from all over Palestine, except Gaza, were studied. All the isolates were resistant to all the β-lactam antibiotics including the carbapenems. Of the 69 isolates, 82.6% were positive for blaOXA-23, 14.5% were positive for blaOXA-24, and 3% were positive for blaOXA-58...
2017: International Journal of Microbiology
https://www.readbyqxmd.com/read/28813122/morphological-alterations-in-the-jejunal-mucosa-of-aged-rats-and-the-possible-protective-role-of-green-tea
#4
Zeinab Abel-Rehim Hassan, Agata Zauszkiewicz-Pawlak, Shaimaa A Abdelrahman, Sami Algaidi, Maha Desouky, Sally M Shalaby
INTRODUCTION: Gastrointestinal disorders become more prevalent with ageing. This study is aimed to describe morphological changes that occur in the jejunal mucosa of male albino rats as a result of ageing and the protective effect of green tea supplements. MATERIAL AND METHODS: The experiment was performed on sixty rats: thirty young-adult (6-month old, body mass 200-220 g) and thirty old (24-month-old, body mass 220-260 g) animals. Each group was further divided into two subgroups (n = 15 each): control rats and green tea-treated rats that received 1...
August 16, 2017: Folia Histochemica et Cytobiologica
https://www.readbyqxmd.com/read/28812931/advocacy-and-public-policy-perceptions-and-involvement-of-master-certified-health-education-specialists
#5
Dianne L Kerr, Emily Van Wasshenova, Rachel Mahas, F Jeannine Everhart, Amy Thompson, Debra Boardley
Master Certified Health Education Specialists (MCHES; n = 186) participated in a mail survey on advocacy and public policy. Over half of participants reported that they had contacted a public official or provided policy-related information to consumers or other professionals. Participants identified barriers and benefits to influencing public policy. The greatest benefit was identified as improving the health or welfare of the public while the greatest barrier was that they were busy with other priorities. Participants also described their level of involvement, knowledge, training in advocacy, and their self-efficacy in performing various advocacy activities...
September 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/28808492/assessment-of-anti-factor-xa-activity-of-enoxaparin-for-venous-thromboembolism-prophylaxis-in-morbidly-obese-surgical-patients
#6
Nouf Al Otaib, Zohour Bootah, Maha A Al Ammari, Tariq M Aldebasi, Abdulmalik M Alkatheri, Shmeylan A Al Harbi, Salah M AbuRuz, Abdulkareem M AlBekairy
BACKGROUND: Venous thromboembolism (VTE) can be encountered by 60% of hospitalized patients. Anticoagulants have been recommended to reduce the risk of VTE in patients with risk factors. However, no specific dosing recommendations for obese patients are provided in the current practice guidelines. The purpose of this study was to determine the efficacy and safety of weight-based dosing of enoxaparin for VTE prophylaxis among morbidly obese patients undergoing surgery. METHODS: Adult patients were enrolled if they have a body mass index (BMI) of ≥35 kg/m(2) and were scheduled for surgery...
July 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/28808307/lc3a-silencing-hinders-aggresome-vimentin-cage-clearance-in-primary-choroid-plexus-carcinoma
#7
Marwa Nassar, Heba Samaha, Myret Ghabriel, Maha Yehia, Hala Taha, Sherin Salem, Khaled Shaaban, Mariam Omar, Nabil Ahmed, Shahenda El-Naggar
Aggresomes are transient microtubule-dependent inclusion bodies that sequester misfolded proteins and are ultimately removed by autophagy. Here we report the generation of a choroid plexus carcinoma cell line; Children's Cancer Hospital Egypt (CCHE)-45, which is characterized by the constitutive formation of aggresomes. When examining the autophagy pathway as the main route for aggresomes clearance, CCHE-45 cells displayed increased autophagy flux mediated by MAP1LC3B. MAP1LC3A-Variant1 gene expression was silenced by promoter methylation...
August 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28804853/thromboelastography-teg
#8
Maha Othman, Harmanpreet Kaur
Thromboelastography (TEG) has been used for decades to guide transfusion therapy during cardiac and hepatic surgeries. Renewed interest and improved technology have led to wider applications of TEG in other areas of hemostasis. To correctly interpret the data generated and to validate outcomes, it is important to improve the understanding of the differences in the currently available assay procedures, the issues related to sample activation, and the importance of the use of appropriate controls. Current TEG assays use a variety of samples and can vary slightly in the procedures...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28800636/combined-sprint-and-resistance-training-abrogates-age-differences-in-somatotropic-hormones
#9
Maha Sellami, Wissem Dhahbi, Lawrence D Hayes, Johnny Padulo, Fatma Rhibi, Hanen Djemail, Anis Chaouachi
The aim of this investigation was to compare serum growth hormone (GH), insulin-like growth factor-1 (IGF-1) and insulin-like growth factor-binding protein-3 (IGFBP-3) in response to a combined sprint and resistance training (CSRT) program in young and middle-aged men.Thirty-eight healthy, moderately trained men participated in this study. Young and middle-aged men were randomly assigned to, a young training group (YT = 10, 21.4±1.2yrs) ora young control group (YC = 9, 21.6±1.8 yrs), a middle-aged training group (MAT = 10, 40...
2017: PloS One
https://www.readbyqxmd.com/read/28797571/epidemiology-of-burn-patients-presenting-to-a-tertiary-hospital-emergency-department-in-lebanon
#10
Abou Dagher Gilbert, Eva Rajha, Christopher El Khuri, Ralph Bou Chebl, Aurelie Mailhac, Maha Makki, Mazen El Sayed
BACKGROUND: The epidemiology of burns is well described in the United States, Europe and Asia. However, few studies address this topic in the Levant region. This study aims to describe characteristics of burn victims treated at the emergency department of a tertiary care center in Beirut, Lebanon and to report on factors that affect ED disposition. METHODS: A retrospective cohort study was conducted in the ED of a tertiary care hospital, in Beirut, Lebanon, between 2009 and 2013...
August 7, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28796839/tissue-specific-control-of-latent-cmv-reactivation-by-regulatory-t-cells
#11
Maha Almanan, Jana Raynor, Allyson Sholl, Mei Wang, Claire Chougnet, Rhonda D Cardin, David A Hildeman
Cytomegalovirus (CMV) causes a persistent, lifelong infection. CMV persists in a latent state and undergoes intermittent subclinical viral reactivation that is quelled by ongoing T cell responses. While T cells are critical to maintain control of infection, the immunological factors that promote CMV persistence remain unclear. Here, we investigated the role of regulatory T cells (Treg) in a mouse model of latent CMV infection using Foxp3-diphtheria toxin receptor (Foxp3-DTR) mice. Eight months after infection, MCMV had established latency in the spleen, salivary gland, lung, and pancreas, which was accompanied by an increased frequency of Treg...
August 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28795898/from-feeling-broken-to-looking-beyond-broken-palestinian-mothers-experiences-of-having-a-child-with-spina-bifida
#12
Maha Sudki Hmeidan Nahal, Helena Wigert, Asma Imam, Åsa B Axelsson
Spina bifida (SB) is the second most common birth defect worldwide. Mothers of children with SB face extraordinary challenges due to the complicated conditions and disability of their children. Little is known about the impact of these challenges on the mothers' well-being, particularly in Middle Eastern culture, where chronic illness and disability are perceived as a stigma, and care of disabled children has traditionally been the responsibility of the mother. The aim of this study was to illuminate mothers' lived experience of having a child with SB in Palestine...
May 2017: Journal of Family Nursing
https://www.readbyqxmd.com/read/28794851/expression-of-jazf1-abcc8-kcnj11and-notch2-genes-and-vitamin-d-receptor-polymorphisms-in-type-2-diabetes-and-their-association-with-microvascular-complications
#13
Maha A Rasheed, Nagwa Kantoush, Nagwa Abd El-Ghaffar, Hebatallah Farouk, Solaf Kamel, Alshaymaa Ahmed Ibrahim, Aliaa Shalaby, Eman Mahmoud, Hala M Raslan, Omneya M Saleh
BACKGROUND: We studied JAZF1, ABCC8, KCNJ11and Notch2 gene expression and vitamin D receptor (VDR) polymorphisms (Fok1 and Bsm1) in patients with type 2 diabetes mellitus (T2DM) and tried to find out their association with microvascular complications in these patients. METHODS: The study was conducted on 180 patients (93 complicated and 87 noncomplicated) and 150 healthy subjects. Reverse-transcriptase polymerase chain reaction (RT-PCR) was used to assess gene expression and real-time PCR was used to detect VDR genotypes...
June 2017: Therapeutic Advances in Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28782054/facet-dependent-diol-induced-density-of-states-of-anatase-tio2-crystal-surface
#14
Maha Chamtouri, Bart Kenens, Remko Aubert, Gang Lu, Tomoko Inose, Yasuhiko Fujita, Akito Masuhara, Johan Hofkens, Hiroshi Uji-I
Owing to their fundamental importance and practical applications, anatase TiO2 crystals with well-defined {001} and {101} facets attracted intensive research interests. In this study, we systematically investigated solvent dependence of the photoreaction of the different coexposed crystal facets during noble metal photodeposition. By examining the deposition position in each solvent, we revealed that solvents play a pivotal role on the facet selectivity. On the basis of density functional theory calculations, the solvent molecules were found to modify both the crystal facet electronic structure and the {001}-{001} heterojunction...
July 31, 2017: ACS Omega
https://www.readbyqxmd.com/read/28777032/suicidal-ideation-in-an-egyptian-sample-of-hospitalized-patients-with-acute-psychosis
#15
Maha Ftouh, El-Sayed Gad, Mohammad A Seleem, Sameh Saada, Ahmed A Mubarak
BACKGROUND: Suicide mortality is 12 times higher in psychotic patients compared to the general population. Identifying characteristic of suicidal patients among this group might help in preventing such behavior. AIMS: To assess the predictors of suicidal risk in patients hospitalized due to acute psychosis. METHODS: One hundred and fifty patients (age 18 - 60 years) admitted with acute psychotic features were recruited. Patients were evaluated clinically by The Arabic version of Mini International Neuropsychiatric Interview (M...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28776373/acyclic-1-4-stereocontrol-via-the-allylic-diazene-rearrangement-development-applications-and-the-essential-role-of-kinetic-e-stereoselectivity-in-tosylhydrazone-formation
#16
Maha L Shrestha, Wei Qi, Matthias C McIntosh
We report full details of a method for 1,3-reductive transposition of α-alkoxy-α,β-unsaturated hydrazones to provide E-alkenes with high 1,4-stereocontrol between the two respective allylic stereocenters. The process couples a chelation-controlled reduction of the hydrazone with an in situ allylic strain controlled retro-ene reaction of an allyl diazene, i.e., an allylic diazene rearrangement. Such stereotriads are frequently observed motifs in natural products. We observed a fortuitous kinetic preference for the E-hydrazone geometry during the hydrazonation reaction, as only the E-isomers could undergo chelation-controlled reduction...
August 4, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28768431/adefovir-dipivoxil-loaded-proliposomal-powders-with-improved-hepatoprotective-activity-formulation-optimization-pharmacokinetic-and-biodistribution-studies
#17
Ghada A Abdelbary, Maha M Amin, Mohamed Y Zakaria, Sally A El Awdan
The present study aimed to prepare proliposomal formulae for improving the oral bioavailability of Adefovir Dipivoxil (AD), a nucleoside reverse transcriptase inhibitor effective against Hepatitis B virus (HBV). The prepared proliposomal formulae were characterized for entrapment efficiency (E.E.%), vesicle size and in-vitro drug release after reconstitution to conventional liposomes. The optimized formula (F9) with a maximum desirability value of 0.858 was selected having E.E.% of 71±3.3% with an average vesicle size of 164...
August 2, 2017: Journal of Liposome Research
https://www.readbyqxmd.com/read/28766478/novel-approach-for-the-simultaneous-determination-of-carbinoxamine-maleate-pholcodine-and-ephedrine-hydrochloride-without-interference-from-coloring-matter-in-an-antitussive-preparation-using-smart-spectrophotometric-methods
#18
Azza A Moustafa, Maha A Hegazy, Dalia Mohamed, Omnia Ali
The presence of coloring matters in syrups usually interferes with the spectrophotometric determination of active pharmaceutical ingredients. A novel approach was introduced to eliminate the interference of sunset yellow (coloring matter) in Cyrinol syrup. Smart, simple, accurate, and selective spectrophotometric methods were developed and validated for the simultaneous determination of a ternary mixture of carbinoxamine maleate, pholcodine, and ephedrine hydrochloride in syrup. Four of the applied methods used ratio spectra: successive derivative subtraction coupled with constant multiplication, successive derivative of ratio spectra, ratio subtraction coupled with ratio difference, and ratio spectra continuous wavelet transforms zero-crossing...
August 1, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28759277/the-experience-of-decision-making-in-the-care-of-children-with-palliative-care-needs-the-experiences-of-jordanian-mothers
#19
Maha Atout, Pippa Hemingway, Jane Seymour
The purpose of this study was to explore the experience of decision making in the care of children with palliative care needs in Jordan, from the perspective of their mothers. This study employed a collective qualitative case study approach. Data were collected in 3 pediatric wards in a Jordanian hospital. The study used 2 data collection methods: participant observation (197 observational hours) and 56 semi-structured interviews with 24 mothers, 12 physicians and 20 nurses. The findings show how Jordanian mothers seek to transfer the role of decision making to physicians, as they perceive themselves to be unable to make decisions about critical issues related to the treatment of their children...
July 31, 2017: Compr Child Adolesc Nurs
https://www.readbyqxmd.com/read/28758037/an-atypical-presentation-of-chronic-atrophic-gastritis-hemolytic-anemia-and-mesenteric-panniculitis
#20
Zurab Azmaiparashvili, Vinicius M Jorge, Catiele Antunes
Microangiopathic hemolytic anemia (MAHA) requires an aggressive approach since primary thrombotic microangiopathy syndromes such as thrombotic thrombocytopenic purpura (TTP) can progress rapidly to a fatal outcome. Differential diagnosis can be challenging even for an experienced hematologist. We present a case of a 52-year-old male who presented with symptoms of mesenteric panniculitis and showed signs of MAHA. His condition was attributed to severe vitamin B12 deficiency secondary to chronic atrophic gastritis and initiation of appropriate therapy was met with complete resolution of symptoms and normalization of hematologic parameters...
2017: Case Reports in Hematology
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