Laurence Ducharme, Sofianne Gabrielli, Ann E Clarke, Judy Morris, Jocelyn Gravel, Rodrick Lim, Edmond S Chan, Ran D Goldman, Andrew O'Keefe, Jennifer Gerdts, Derek K Chu, Julia Upton, Elana Hochstadter, Adam Bretholz, Christine McCusker, Xun Zhang, Moshe Ben-Shoshan
BACKGROUND: Data are sparse regarding tree nut-induced anaphylaxis (TNA). OBJECTIVE: To characterize rate, clinical characteristics, and management of TNA in children (0-17 years old) across Canada and evaluate factors associated with severe reactions and epinephrine use. METHODS: Between April 2011 and May 2020, data were collected on children presenting to 5 emergency departments in Canada. Multivariate logistic analysis was used to evaluate factors associated with severe reactions (stridor, cyanosis, circulatory collapse, or hypoxia) and epinephrine use...
September 2022: Annals of Allergy, Asthma & Immunology