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https://www.readbyqxmd.com/read/28503113/who-s-the-leader-mania-or-depression-predominant-polarity-and-alcohol-polysubstance-use-in-bipolar-disorders
#1
Delfina Janiri, Marco Di Nicola, Giovanni Martinotti, Luigi Janiri
BACKGROUND: Predominant polarity characterises patients who mainly manifest recurrences of depression or mania/hypomania. Alcohol use disorder (AUD) and polysubstance use (PSU), which often complicate bipolar disorder (BD) and affect its clinical course, can influence predominant polarity. Nevertheless, previous studies have not clarified if BD patients differ in predominant polarity from BD patients with substance use disorder (SUD) comorbidity. OBJECTIVE: The aim of this study was to compare predominant polarity between BD without SUD, BD with AUD and BD with PSU...
April 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28501595/corticolimbic-circuitry-in-the-modulation-of-chronic-pain-and-substance-abuse
#2
REVIEW
Anna M W Taylor
The transition from acute to chronic pain is accompanied by increased engagement of emotional and motivational circuits. Adaptations within this corticolimbic circuitry contribute to the cellular and behavioral maladaptations associated with chronic pain. Central regions within the corticolimbic brain include the mesolimbic dopamine system, the amygdala, and the medial prefrontal cortex. The evidence reviewed herein supports the notion that chronic pain induces significant changes within these corticolimbic regions that contribute to the chronicity and intractability of pain...
May 10, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28496365/prevalence-and-prognosis-of-stress-disorders-a-review-of-the-epidemiologic-literature
#3
REVIEW
Jaimie L Gradus
Given the ubiquity of traumatic events, it is not surprising that posttraumatic stress disorder (PTSD) - a common diagnosis following one of these experiences - is characterized as conferring a large burden for individuals and society. Although there is recognition of the importance of PTSD diagnoses throughout psychiatry, the literature on other diagnoses one may receive following a stressful or traumatic event is scant. This review summarizes the literature on stress disorders (classified according to the International Classification of Diseases, 10th Edition [ICD-10]), including acute stress reaction, PTSD, adjustment disorder and unspecified stress reactions...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28493652/vitamin-d-deficiency-associated-with-cognitive-functioning-in-psychotic-disorders
#4
Mari Nerhus, Akiah O Berg, Carmen Simonsen, Marit Haram, Beathe Haatveit, Sandra R Dahl, Tiril P Gurholt, Thomas D Bjella, Torill Ueland, Ole A Andreassen, Ingrid Melle
BACKGROUND: Cognitive dysfunctions are core features of psychotic disorders with substantial impact on daily functioning. Vitamin D deficiency has been found to be related to cognitive dysfunctions, but the associations between vitamin D deficiency and cognition in persons with a psychotic disorder are largely unknown. METHODS: This cross-sectional study included 225 patients with a DSM-IV psychotic disorder consecutively recruited from 2003 to 2014 and 159 randomly selected healthy controls, assessed by a cognitive test battery, a clinical protocol (including Structured Clinical Interview for DSM-IV Axis I Disorders and Positive and Negative Syndrome Scale), and a physical examination including vitamin D measurements...
May 9, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28492425/identifying-patient-and-provider-specific-gaps-in-care-among-patients-with-hepatitis-b
#5
Tatyana Kushner, Robert Lam, Daniel L Gray, David E Kaplan, Marina Serper
GOALS: To examine patient, provider, and health system barriers to clinical follow-up among US veterans with chronic hepatitis B virus (HBV). BACKGROUND: Studies have demonstrated deficiencies in clinical care and follow-up in HBV; however, patient, provider, and health-system barriers in non-Asian populations are understudied. STUDY: A retrospective cohort of 517 US veterans with chronic HBV at 3 diverse Veterans Affairs sites from 1999 to 2015...
May 10, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28476266/cocaine-using-substance-abuse-treatment-patients-with-and-without-hiv-respond-well-to-contingency-management-treatment
#6
Ashley E Burch, Carla J Rash, Nancy M Petry
HIV is common among individuals with substance use disorders, but relatively few studies have examined the impact of HIV status on response to substance abuse treatment. This secondary analysis compared patients seeking treatment for cocaine use with and without HIV in terms of substance use treatment outcomes. Primary treatment outcomes included treatment retention, longest duration of abstinence, and percent of negative samples; both substance use outcomes reflect abstinence from cocaine, alcohol and opioids concurrently...
June 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28475942/distinct-cognitive-performance-and-patterns-of-drug-use-among-early-and-late-onset-cocaine-users
#7
Bruna Mayara Lopes, Priscila Dib Gonçalves, Mariella Ometto, Bernardo Dos Santos, Mikael Cavallet, Tiffany Moukbel Chaim-Avancini, Mauricio Henriques Serpa, Sergio Nicastri, André Malbergier, Geraldo F Busatto, Arthur Guerra de Andrade, Paulo Jannuzzi Cunha
INTRODUCTION: Adolescence is a crucial period for neurodevelopment, but few studies have investigated the impact of early cocaine use on cognitive performance and patterns of substance use. METHODS: We evaluated 103 cocaine dependent inpatients divided in two groups: early-onset users (EOG; n=52), late-onset users (LOG; n=51), and 63 healthy controls. Neuropsychological functioning was evaluated using Digits Forward (DF) and Backward (DB), Trail Making Test (TMT), Stroop Color Word Test (SCWT), Controlled Oral Word Association Test (COWAT), Wisconsin Card Sorting Test (WCST), Rey Osterrieth Complex Figure Test (ROCFT), Frontal Assessment Battery (FAB), and Iowa Gambling Test (IGT)...
April 29, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28475905/the-social-cost-of-illicit-drugs-use-in-spain
#8
Berta Rivera, Bruno Casal, Luis Currais
BACKGROUND: Illegal drugs consumption not only has a notable impact on the population's health, but also leads to major socio-economic costs. A significant characteristic of drug consumers is that the majority are of working age. The main aim of this study is to estimate the economic impact of drug consumption in Spain from a social perspective. METHODS: A cost-of-illness methodology is carried out and a distinction is made between health-related and non-health related direct costs, as well as indirect costs...
May 2, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28472697/occurrence-and-fate-of-illicit-drugs-and-pharmaceuticals-in-wastewater-from-two-wastewater-treatment-plants-in-costa-rica
#9
Ana Causanilles, Clemens Ruepert, María Ibáñez, Erik Emke, Félix Hernández, Pim de Voogt
Chemical analysis of raw wastewater in order to assess the presence of biological markers entering a wastewater treatment plant can provide objective information about the health and lifestyle of the population connected to the sewer system. This work was performed in a tropical country of Central America, Costa Rica, with the aim of extending this knowledge to new world regions. This work is the first to report wastewater-based epidemiological data on the use of illicit drugs in this region of the world. Composite wastewater samples from the influents of two different wastewater treatment facilities and surface water samples from surrounding areas were collected applying the best practice protocol and analysed to investigate the occurrence and fate of selected illicit drugs of abuse and pharmaceuticals...
May 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28472407/traumatic-brain-injury-and-attempted-suicide-among-veterans-of-the-wars-in-iraq-and-afghanistan
#10
Jennifer R Fonda, Lisa Fredman, Susan B Brogly, Regina E McGlinchey, William P Milberg, Jaimie L Gradus
Studies of the association between traumatic brain injury (TBI) and suicide attempt have yielded conflicting results. Furthermore, no studies have examined the possible mediating role of common comorbid psychiatric conditions in this association. This study used Veterans Affairs registry data to evaluate the associations between deployment-related TBI, psychiatric diagnoses, and attempted suicide among 273,591 veterans deployed in support of Operation Enduring Freedom, Operation Iraqi Freedom, and Operation New Dawn, and who received care from the Department of Veterans Affairs during 2007-2012...
May 3, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28451465/intimate-partner-violence-victimization-in-lgbt-young-adults-demographic-differences-and-associations-with-health-behaviors
#11
Tyson R Reuter, Michael E Newcomb, Sarah W Whitton, Brian Mustanski
OBJECTIVE: Intimate partner violence (IPV) is an important public health problem with high prevalence and serious costs. Although literature has largely focused on IPV among heterosexuals, studies have recently begun examining IPV in LGBT samples, with mounting evidence suggesting IPV may be more common among LGBT individuals than heterosexuals. Less research has examined the specific health consequences of IPV in this population, particularly across time and among young people, and it remains unclear whether experiences of IPV differ between subgroups within the LGBT population (e...
January 2017: Psychology of Violence
https://www.readbyqxmd.com/read/28444484/effectiveness-of-drug-camps-in-treatment-of-substance-abuse-in-thailand
#12
Manop Kanato, Poonrut Leyatikul
Various drug camps have been introduced in Thailand since the 2000s. This study explored the effects of drug camps in Thailand. Four provinces were selected to represent different region throughout Thailand. Assessments of 2679 drug users were carried out longitudinally, age ranging from 11 to 67 years old; assessments occurred before camp, after camps, and after a 1 year follow-up. Two hundred twenty-six camps organizers, community leaders, and lay people were selected as key informants. Twenty communities were observed prospectively and 400 lay people were studied...
April 25, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28432939/the-association-of-psychiatric-comorbidity-with-treatment-completion-among-clients-admitted-to-substance-use-treatment-programs-in-a-u-s-national-sample
#13
Noa Krawczyk, Kenneth A Feder, Brendan Saloner, Rosa M Crum, Marc Kealhofer, Ramin Mojtabai
BACKGROUND: Psychiatric disorders are highly comorbid with substance use disorders and play an important role in their course and recovery. However, the impact of comorbidity on treatment outcomes has not been examined in a U.S. national sample. This study explores the impact of psychiatric comorbidity on treatment completion among individuals admitted to publicly funded substance use treatment facilities across the United States. METHODS: Using data on first-time treatment episodes in the U...
April 19, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28427471/quality-of-life-and-healthcare-service-utilization-among-methadone-maintenance-patients-in-a-mountainous-area-of-northern-vietnam
#14
Long Hoang Nguyen, Lan Huong Thi Nguyen, Victoria L Boggiano, Canh Dinh Hoang, Hung Van Nguyen, Huong Thi Le, Hai Quan Le, Tho Dinh Tran, Bach Xuan Tran, Carl A Latkin, Nabil Zary, Minh Thuc Thi Vu
BACKGROUND: The expansion of methadone maintenance treatment in mountainous areas in still limited and little is known about its health impacts on drug users. This study aimed to examine health-related quality of life (HRQOL) and health care access among patients engaging in methadone maintenance treatment (MMT) in Tuyen Quang, a mountainous province in Vietnam. METHODS: We conducted a cross-sectional survey with 241 patients conveniently recruited in two MMT clinics (Son Duong and Tuyen Quang)...
April 20, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28426546/methamphetamine-use-and-dependence-in-vulnerable-female-populations
#15
Phunnapa Kittirattanapaiboon, Soontaree Srikosai, Apisak Wittayanookulluk
PURPOSE OF REVIEW: The study reviews recent publications on methamphetamine use and dependence women in term of their epidemic, physical health impact, psychosocial impacts, and also in the identified vulnerable issues. RECENT FINDINGS: Studies of vulnerable populations of women are wide ranging and include sex workers, sexual minorities, homeless, psychiatric patients, suburban women, and pregnant women, in which amphetamine type stimulants (ATSs) are the most commonly reported illicit drug used among them...
April 19, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28424105/specific-impact-of-stimulant-alcohol-and-cannabis-use-disorders-on-first-episode-psychosis-2-year-functional-and-symptomatic-outcomes
#16
C Ouellet-Plamondon, A Abdel-Baki, É Salvat, S Potvin
BACKGROUND: Many studies have concluded that cannabis use disorder (CUD) negatively influences outcomes in first-episode psychosis (FEP). However, few have taken into account the impact of concurrent misuse of other substances. METHODS: This 2-year, prospective, longitudinal study of FEP patients, aged between 18 and 30 years, admitted to early intervention programs in Montreal, Quebec, Canada, examined the specific influence of different substance use disorders (SUD) (alcohol, cannabis, cocaine, amphetamines) on service utilization, symptomatic and functional outcomes in FEP...
April 20, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28423789/using-electronic-health-records-to-assess-depression-and-cancer-comorbidities
#17
Miguel A Mayer, Alba Gutierrez-Sacristan, Angela Leis, Santiago De La Peña, Ferran Sanz, Laura I Furlong
Comorbid diseases are an important concern in oncology since they can affect the choice and effectiveness of treatment. What is particularly relevant is the fact that the diagnosis of depression in cancer patients has an important impact on the quality of life of these patients. Although there is no consensus about a specific relationship of depression with certain cancer types, some authors have proposed that depression constitutes a risk factor for cancer. The objective of this study is to identify the presence of comorbidities in a massive EHR system, between depression and the 10 most common cancers in women and men and to determine if there is a preferred temporal ordering in the co-occurrence of these diseases...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28416810/the-joint-impact-of-cognitive-performance-in-adolescence-and-familial-cognitive-aptitude-on-risk-for-major-psychiatric-disorders-a-delineation-of-four-potential-pathways-to-illness
#18
K S Kendler, H Ohlsson, R S E Keefe, K Sundquist, J Sundquist
How do joint measures of premorbid cognitive ability and familial cognitive aptitude (FCA) reflect risk for a diversity of psychiatric and substance use disorders? To address this question, we examined, using Cox models, the predictive effects of school achievement (SA) measured at age 16 and FCA-assessed from SA in siblings and cousins, and educational attainment in parents-on risk for 12 major psychiatric syndromes in 1 140 608 Swedes born 1972-1990. Four developmental patterns emerged. In the first, risk was predicted jointly by low levels of SA and high levels of FCA-that is a level of SA lower than would be predicted from the FCA...
April 18, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28410131/substance-use-disorder-a-bio-directional-subset-of-reward-deficiency-syndrome
#19
Kenneth Blum, Mark Gold, Zsolt Demetrovics, Trevor Archer, Panayotis K Thanos, David Baron, Rajendra D Badgaiyan
This commentary is to inform clinicians challenged with an increase in people seeking treatment for Substance Use Disorder (SUD), that the ninety percent revolving door, is, in part, due to post-withdrawal, untreated neurotoxicity. This impairment attenuates neurotransmitter signaling and compromises resting state functional connectivity, leading to unwanted sequelae including depression, sleep disturbances, sensation seeking, lack of satisfaction and impulsivity. Neuroimaging studies indicate that neurobiological recovery can take years...
June 1, 2017: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/28409741/impact-of-comorbidities-among-medicaid-enrollees-with-chronic-obstructive-pulmonary-disease-united-states-2009
#20
Gloria Westney, Marilyn G Foreman, Junjun Xu, Marshaleen Henriques King, Eric Flenaugh, George Rust
INTRODUCTION: Multimorbidity, the presence of 2 or more chronic conditions, frequently affects people with chronic obstructive pulmonary disease (COPD). Many have high-cost, highly complex conditions that have a substantial impact on state Medicaid programs. We quantified the cost of Medicaid-insured patients with COPD co-diagnosed with other chronic disorders. METHODS: We used nationally representative Medicaid claims data to analyze the impact of comorbidities (other chronic conditions) on the disease burden, emergency department (ED) use, hospitalizations, and total health care costs among 291,978 adult COPD patients...
April 13, 2017: Preventing Chronic Disease
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