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https://www.readbyqxmd.com/read/28203127/a-case-of-mysterious-impacted-duodenal-foreign-body-presenting-with-halitosis
#1
Bhavtosh Dedania, Dipen Khanapara, Amruta Panwala, Murali Dharan
The majority of gastrointestinal (GI) foreign bodies (FBs) discovered in adults are the result of intentional ingestion, most of which are found in patients with a preexisting psychiatric illness, with substance abuse disorders, or in people seeking secondary gain. No similar case of internal injuries following unintentional ingestion of a barbecue grill cleaning brush bristle has been reported. A 58-year-old Caucasian male with no significant history presented with complaint of halitosis, not improving after oral care and dental hygiene measures...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28195778/transitioning-from-medicaid-disability-coverage-to-long-term-medicare-coverage-the-case-of-people-living-with-hiv-aids-in-california
#2
Warren S Comulada, Katherine A Desmond, Jennifer L Gildner, Arleen A Leibowitz
Medicaid can serve as a bridge to Medicare coverage for the long-term disabled with sufficient covered work experience. We perform multinomial logistic regression on 2007-2010 Medicare and Medicaid claims data to examine transitions to Medicare for people living with HIV/AIDS (PLWHA) in California who had Medicaid coverage in 2007. We find only 16% had obtained Medicare coverage by 2010. African-Americans, women, individuals with schizophrenia diagnoses, alcohol or substance abuse disorders, and any physical comorbidity were significantly less likely than others to obtain Medicare (p < 0...
February 2017: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://www.readbyqxmd.com/read/28190543/quality-of-life-as-an-outcome-of-opioid-use-disorder-treatment-a-systematic-review
#3
Jeremy W Bray, Brandon Aden, Ashley A Eggman, Leah Hellerstein, Eve Wittenberg, Bohdan Nosyk, Judy C Stribling, Bruce R Schackman
BACKGROUND AND AIMS: The recent opioid epidemic has prompted renewed interest in opioid use disorder treatment, but there is little evidence regarding health-related quality-of-life (HRQoL) outcomes in treatment programs. Measuring HRQoL represents an opportunity to consider outcomes of opioid use disorder treatment that are more patient-centered and more relevant to overall health than abstinence alone. We conducted a systematic literature review to explore the extent to which the collection of HRQoL by opioid treatment programs is documented in the treatment program literature...
February 10, 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28168645/everything-in-moderation-moderate-use-of-screens-unassociated-with-child-behavior-problems
#4
Christopher J Ferguson
The impact of children's use of "screen" media including television and computer games, continues to be debated. The American Academy of Pediatrics (AAP) until recently recommended a relatively restrictive screen time diet of 2 h or less for most youth. A representative correlational sample of youth were assessed for links between screen time and risky behavioral outcomes. Data collection occurred in 2013 conducted by the State of Florida. Use of screens that was moderately high, in excess of the AAP's former recommendations, but not excessive (1 SD or higher than average), was not associated with delinquency, risky behaviors, sexual behaviors, substance abuse, reduced grades or mental health problems...
February 7, 2017: Psychiatric Quarterly
https://www.readbyqxmd.com/read/28166480/the-need-for-data-informed-clinical-supervision-in-substance-use-disorder-treatment
#5
Alex T Ramsey, Ana Baumann, David Patterson, Yan Yan, Ben Cooper, Enola Proctor
BACKGROUND: Effective clinical supervision is necessary for high-quality care in community-based substance use disorder treatment settings, yet little is known about current supervision practices. Some evidence suggests that supervisors and counselors differ in their experiences of clinical supervision; however, the impact of this misalignment on supervision quality is unclear. Clinical information monitoring systems may support supervision in substance use disorder treatment, but the potential use of these tools must first be explored...
February 6, 2017: Journal of Addictive Diseases
https://www.readbyqxmd.com/read/28163028/a-nationwide-pharmacy-chain-responds-to-the-opioid-epidemic
#6
Emily Shafer, Nyahne Bergeron, Renae Smith-Ray, Chester Robson, Rachel O'Koren
OBJECTIVES: To describe the 3-pronged approach taken by a large national retail pharmacy chain to address the opioid epidemic and associated overdoses. SETTING: Large national retail pharmacy chain with more than 8200 stores in 50 states. PRACTICE DESCRIPTION: Eight million customer interactions daily through in-store and digital settings. This is a company with a long history of responding to public health crises. PRACTICE INNOVATION: Initiated 3 programs to respond to the opioid crisis: 1) provide safe medication disposal kiosks; 2) expand national access to naloxone; and 3) provide education on the risk and avoidance of opioid overdose...
February 2, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28161446/drunk-bugs-chronic-vapour-alcohol-exposure-induces-marked-changes-in-the-gut-microbiome-in-mice
#7
Veronica L Peterson, Nicholas J Jury, Raúl Cabrera-Rubio, Lorraine A Draper, Fiona Crispie, Paul D Cotter, Timothy G Dinan, Andrew Holmes, John F Cryan
The gut microbiota includes a community of bacteria that play an integral part in host health and biological processes. Pronounced and repeated findings have linked gut microbiome to stress, anxiety, and depression. Currently, however, there remains only a limited set of studies focusing on microbiota change in substance abuse, including alcohol use disorder. To date, no studies have investigated the impact of vapour alcohol administration on the gut microbiome. For research on gut microbiota and addiction to proceed, an understanding of how route of drug administration affects gut microbiota must first be established...
February 1, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28116588/early-onset-of-sexual-intercourse-and-parental-incarceration-among-african-american-youth-living-in-urban-public-housing
#8
Von E Nebbitt, Dexter R Voisin, M Taqi Tirmazi
Mass incarceration, substance use, and adolescent early onset of sex (e.g., initiate sexual intercourse at 13 years of age or younger) are social problems with disparate impacts on low-income African American communities. Two out of every five inmates in state and federal prisons are African American and the vast majority of these inmates are from low-income communities. Furthermore, this population experiences more severe consequences of substance use and abuse compared to other populations. In sum, African American youth endure the lion share of problems that mass incarceration and substance use leave in their wake...
January 23, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28111268/impact-of-adolescent-social-experiences-on-behavior-and-neural-circuits-implicated-in-mental-illnesses
#9
REVIEW
Andrew R Burke, Cheryl M McCormick, Sergio M Pellis, Jodi L Lukkes
Negative social experiences during adolescence are central features for several stress-related mental illnesses. Social play fighting behavior in rats peaks during early adolescence and is essential for the final maturation of brain and behavior. Manipulation of the rat adolescent social experience alters many neurobehavioral measurements implicated in anxiety, depression, and substance abuse. In this review, we will highlight the importance of social play and the use of three separate social stress models (isolation-rearing, social defeat, and social instability stress) to disrupt the acquisition of this adaptive behavior...
January 19, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28109342/developmental-lead-exposure-induces-opposite-effects-on-ethanol-intake-and-locomotion-in-response-to-central-vs-systemic-cyanamide-administration
#10
Mara Soledad Mattalloni, Romina Deza-Ponzio, Paula Alejandra Albrecht, Liliana Marina Cancela, Miriam Beatriz Virgolini
Lead (Pb) is a developmental neurotoxicant that elicits differential responses to drugs of abuse. Particularly, ethanol consumption has been demonstrated to be increased as a consequence of environmental Pb exposure, with catalase (CAT) and brain acetaldehyde (ACD, the first metabolite of ethanol) playing a role. The present study sought to interfere with ethanol metabolism by inhibiting ALDH2 (mitochondrial aldehyde dehydrogenase) activity in both liver and brain from control and Pb-exposed rats as a strategy to accumulate ACD, a substance that plays a major role in the drug's reinforcing and/or aversive effects...
February 2017: Alcohol
https://www.readbyqxmd.com/read/28105985/impact-of-traumatic-brain-injury-on-dopaminergic-transmission
#11
Yuan-Hao Chen, Eagle Yi-Kung Huang, Tung-Tai Kuo, Jonathan Miller, Yung-Hsiao Chiang, Barry J Hoffer
Brain trauma is often associated with severe morbidity and is a major public health concern. Even when injury is mild and no obvious anatomic disruption is seen, many individuals suffer disabling neuropsychological impairments such as memory loss, mood dysfunction, substance abuse, and adjustment disorder. These changes may be related to subtle disruption of neural circuits as well as functional changes at the neurotransmitter level. In particular, there is considerable evidence that dopamine physiology in the nigrostriatal and mesocorticolimbic pathways might be impaired after TBI...
January 20, 2017: Cell Transplantation
https://www.readbyqxmd.com/read/28101955/prescription-drug-monitoring-programs-produce-a-limited-impact-on-painkiller-prescribing-in-medicare-part-d
#12
Courtney R Yarbrough
OBJECTIVE: To measure the impact of prescription drug monitoring programs (PDMPs) on prescribing of opioid and nonopioid painkillers. DATA SOURCE: 2010-2013 physician-level Medicare Part D prescribing data released by the Centers for Medicare and Medicaid Services and Propublica. STUDY DESIGN: Using difference-in-differences models with physician-level fixed effects, the study compares prescribing in states with and without PDMPs for opioid and nonopioid analgesics, oxycodone, hydrocodone, and opioids by controlled substances Schedules II-IV...
January 18, 2017: Health Services Research
https://www.readbyqxmd.com/read/28097048/effects-of-grazing-intensity-and-the-use-of-veterinary-medical-products-on-dung-beetle-biodiversity-in-the-sub-mountainous-landscape-of-central-italy
#13
Mattia Tonelli, José R Verdú, Mario E Zunino
Grazing extensification and intensification are among the main problems affecting European grasslands. We analyze the impact of grazing intensity (low and moderate) and the use of veterinary medical products (VMPs) on the dung beetle community in the province of Pesaro-Urbino (Italy). Grazing intensity is a key factor in explaining the diversity of dung beetles. In the case of the alpha diversity component, sites with a low level of grazing activity-related in a previous step to the subsequent abandonment of traditional farming-is characterized by a loss of species richness (q = 0) and a reduction in alpha diversity at the levels q = 1 and q = 2...
2017: PeerJ
https://www.readbyqxmd.com/read/28095283/substance-use-among-european-students-east-west-comparison-between-1995-and-2011
#14
Alojz Nociar, Janusz Sierosławski, Ladislav Csémy
AIM: The aim of the study was to investigate long-term trends differences in student substance misuse between countries of former Eastern Bloc (FEB) and Western Europe (WEST). Overall data on student substance misuse gathered in five waves of the European School Survey Project on Alcohol and other Drugs (ESPAD) conducted between 1995 and 2011 were pooled and analysed. Findings were compared between FEB and WEST countries at the five time-points of data collection. METHODS: Over 396,000 of 16 years old students from thirteen FEB and thirteen WEST countries completed anonymous ESPAD questionnaires...
December 2016: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28087443/an-update-on-the-physiological-and-therapeutic-relevance-of-gpcr-oligomers
#15
REVIEW
Batoul Farran
The traditional view on GPCRs held that they function as single monomeric units composed of identical subunits. This notion was overturned by the discovery that GPCRs can form homo- and hetero-oligomers, some of which are obligatory, and can further assemble into receptor mosaics consisting of three or more protomers. Oligomerisation exerts significant impacts on receptor function and physiology, offering a platform for the diversification of receptor signalling, pharmacology, regulation, crosstalk, internalization and trafficking...
January 11, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/28076644/main-mental-disorders-in-crack-cocaine-users-treated-at-psychosocial-care-centers-for-alcohol-and-drugs-in-the-city-of-recife-brazil
#16
Antonio Gomes de Castro, Diego César Nunes da Silva, Magda da Silva Figueiroa
Introduction: Brazil's Northeast region has the highest crack-cocaine consumption in the country. Crack-cocaine has more intense effects than cocaine powder and can cause greater chemical dependence. Psychosocial Care Centers for Alcohol and Drugs (CAPSad) are public health services that provide treatment for drug dependence. It is common for drug users, and particularly crack-cocaine users, to develop mental disorders. Objective: To evaluate the most common mental disorders in crack-cocaine dependents in treatment at CAPSad in the city of Recife, Brazil...
October 2016: Trends in Psychiatry and Psychotherapy
https://www.readbyqxmd.com/read/28072643/early-life-trauma-in-hospitalized-patients-with-mood-disorders-and-its-association-with-clinical-outcomes
#17
Ajay K Parsaik, Noha Abdelgawad, Jigar K Chotalia, Scott D Lane, Teresa A Pigott
BACKGROUND: The prevalence of childhood trauma and its impact on clinical outcomes in hospitalized patients with mood disorders is unknown. We studied the frequency of childhood trauma among inpatient adults with mood disorders and its association with clinical outcomes. METHODS: Patients admitted to our hospital with a primary diagnosis of mood disorders completed the short form of the Early Trauma Inventory-Self-Report (ETISR-SF), the Sheehan Disability Scale, and the Clinician-Rated Dimensions of Psychosis Symptom Severity scale...
January 2017: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/28070918/stereotype-threat-and-social-function-in-opioid-substitution-therapy-patients
#18
Courtney von Hippel, Julie D Henry, Gill Terrett, Kimberly Mercuri, Karen McAlear, Peter G Rendell
OBJECTIVES: People with a history of substance abuse are subject to widespread stigmatization. It seems likely that this societal disapproval will result in feelings of stereotype threat, or the belief that one is the target of demeaning stereotypes. If so, stereotype threat has the potential to contribute to functional difficulties including poor social outcomes. METHODS: Eighty drug users on opioid substitution therapy and 84 demographically matched controls completed measures of mental health and social function...
January 10, 2017: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28067741/hypertensive-medications-in-competitive-athletes
#19
Henry Pelto
Hypertension is the most common cardiovascular disease in athletes. It is an important cause of long-term morbidity and mortality, even in a fit, athletic population. Management options to reduce these long-term risks exist that have minimal impact on athletic performance. Identification and management of underlying lifestyle factors and diseases that may lead to secondary hypertension is critical. These include substance abuse, medications, and underlying medical conditions. After evaluation and management of these issues, medications can be used to reduce blood pressure...
January 2017: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/28062923/cardiovascular-disease-and-psychiatric-disorders-among-latinos-in-the-united-states
#20
Leopoldo J Cabassa, Roberto Lewis-Fernández, Shuai Wang, Carlos Blanco
PURPOSE: Cardiovascular disease (CVD) is the leading cause of death among Latinos and disproportionately impacts people with psychiatric disorders. The aim of this study was to examine the relationships between CVD and psychiatric disorders among different Latino subgroups using a nationally representative sample. METHODS: Latinos participants (N = 6359) were drawn from Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions. A structured diagnostic interview was used to determine psychiatric diagnoses for any past-year mood, anxiety, and substance use disorders...
January 6, 2017: Social Psychiatry and Psychiatric Epidemiology
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