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Knowledge Retention

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https://www.readbyqxmd.com/read/29453412/pulmonary-antigen-encounter-regulates-the-establishment-of-tissue-resident-cd8-memory-t-cells-in-the-lung-airways-and-parenchyma
#1
Sean R McMaster, Alexander N Wein, Paul R Dunbar, Sarah L Hayward, Emily K Cartwright, Timothy L Denning, Jacob E Kohlmeier
Resident memory CD8 T (T RM ) cells in the lung parenchyma (LP) and airways provide heterologous protection against influenza virus challenge. However, scant knowledge exists regarding factors necessary to establish and maintain lung CD8 T RM . Here we demonstrate that, in contrast to mechanisms described for other tissues, airway, and LP CD8 T RM establishment requires cognate antigen recognition in the lung. Systemic effector CD8 T cells could be transiently pulled into the lung in response to localized inflammation, however these effector cells failed to establish tissue residency unless antigen was present in the pulmonary environment...
February 16, 2018: Mucosal Immunology
https://www.readbyqxmd.com/read/29453022/exploring-factors-that-influence-students-attitudes-toward-midwifery-in-jordan-measuring-psychometric-properties-of-a-newly-developed-tool
#2
Lourance A Al Hadid, Omaymah Al-Rajabi, Marwa AlBarmawi, Najah Sayyah Yousef Sayyah, Lwiza Moh'd Toqan
Students' professional choice to proceed in midwifery is influenced by many factors. This study validated an instrument developed to assess students' attitudes toward midwifery in Jordan. It also addressed the motivating and de-motivating factors influencing students' decision concerning joining and continuing in midwifery. A descriptive, cross-section study was conducted on a convenience sample of 374 midwifery students representing private, governmental, and military midwifery colleges. The researchers developed the study questionnaire through conducting a comprehensive literature review, organizing common themes and consulting experts...
February 8, 2018: Nurse Education in Practice
https://www.readbyqxmd.com/read/29449958/a-mobile-phone-based-program-to-promote-healthy-behaviors-among-adults-with-prediabetes-study-protocol-for-a-pilot-randomized-controlled-trial
#3
Dina H Griauzde, Jeffrey T Kullgren, Brad Liestenfeltz, Caroline Richardson, Michele Heisler
Background: Rates of participation in Diabetes Prevention Programs (DPPs) are low. This may be due, in part, to low levels of autonomous motivation (i.e., motivation that arises from internal sources and sustains healthy behaviors over time) to prevent type 2 diabetes (T2DM) among many individuals with prediabetes. Mobile health (mHealth) technologies that incorporate principles from the Self-Determination Theory offer an effective and scalable approach to increase autonomous motivation levels...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29449201/peer-coaching-through-mhealth-targeting-physical-activity-in-people-with-parkinson-disease-feasibility-study
#4
Cristina Colón-Semenza, Nancy K Latham, Lisa M Quintiliani, Terry D Ellis
BACKGROUND: Long-term engagement in exercise and physical activity mitigates the progression of disability and increases quality of life in people with Parkinson disease (PD). Despite this, the vast majority of individuals with PD are sedentary. There is a critical need for a feasible, safe, acceptable, and effective method to assist those with PD to engage in active lifestyles. Peer coaching through mobile health (mHealth) may be a viable approach. OBJECTIVE: The purpose of this study was to develop a PD-specific peer coach training program and a remote peer-mentored walking program using mHealth technology with the goal of increasing physical activity in persons with PD...
February 15, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29446742/development-of-an-in-vitro-drug-delivery-efficiency-test-for-a-pulmonary-toxicokinetic-pig-study
#5
Nadine Schaefer, Ann-Katrin Kroll, Matthias W Laschke, Michael D Menger, Hans H Maurer, Markus R Meyer, Peter H Schmidt
BACKGROUND: Since their appearance on the drugs of abuse market, synthetic cannabinoids (SCs) are gaining increasing toxicological relevance. They are consumed without knowledge of their toxicokinetic (TK) and toxicodynamic properties and human studies are not allowed due to ethical reasons. A controlled animal TK study following nebulization of 4-ethylnaphthalene-1-yl-(1-pentylindole-3-yl)methanone (JWH-210), 2-(4-methoxyphenyl)-1-(1-pentyl-indole-3-yl)methanone (RCS-4) as well as Δ9-tetrahydrocannabinol (THC) to pigs should be helpful for better interpretation of analytical results in cases of misuse or poisoning...
February 14, 2018: Current Drug Delivery
https://www.readbyqxmd.com/read/29445515/telementoring-with-project-echo-a-pilot-study-in-europe
#6
Clíona Ní Cheallaigh, Aisling O'Leary, Shay Keating, Aileen Singleton, Sheila Heffernan, Eamon Keenan, Lisa Robson, Jess Sears, John Moloney, Sanjeev Arora, Colm Bergin, Suzanne Norris
The Extension of Community Healthcare Outcomes (ECHO) project is a novel educational intervention designed in New Mexico to transfer subspecialty knowledge about hepatitis C virus (HCV) to primary care providers, thereby increasing patient access to HCV care. The ECHO model has been shown to deliver educational benefits and to result in good treatment outcomes for HCV-infected individuals in the USA; however, this approach has not been assessed in a European setting. We sought to evaluate the feasibility, acceptability and implementation of the ECHO model in Ireland using a pilot study...
July 2017: BMJ Innovations
https://www.readbyqxmd.com/read/29443502/direct-classification-of-gc-%C3%A3-gc-analyzed-complex-mixtures-using-non-negative-matrix-factorization-based-feature-extraction
#7
Yasuyuki Zushi, Shunji Hashimoto
Complex chemical mixtures need to be evaluated to, for example, aid in medical diagnoses, assess product quality, and assess environmental conditions. Two-dimensional gas chromatography (GC × GC), which is a comprehensive analytical technique, combined with data classification techniques has attracted great interest for assessing mixtures. In this study, a nontarget cross-sample analysis-based unsupervised direct classification method using non-negative matrix factorization was developed for assessing mixtures analyzed by GC × GC...
February 14, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29436071/the-impact-of-a-short-educational-movie-on-promoting-chronic-pain-health-literacy-in-school-a-feasibility-study
#8
J Wager, L Stahlschmidt, F Heuer, S Troche, B Zernikow
BACKGROUND: School-based health education programs on chronic pain providing information about the proper management of recurrent and chronic pain may increase health literacy in terms of pain knowledge and may thereby prevent dysfunctional coping and may decrease the risk of pain chronification. The aim of the present feasibility study was to evaluate the effectiveness of an educational movie on recurrent and chronic pain in increasing pain knowledge among students. METHODS: N=95 adolescent students provided demographic and pain-related information and completed a pain knowledge questionnaire before and after viewing an educational movie on recurrent and chronic pain...
February 13, 2018: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29433728/bronchoscopy-education-an-experiential-learning-theory-perspective
#9
REVIEW
Septimiu D Murgu, Jonathan S Kurman, Omar Hasan
Bronchoscopy programs implementing the experiential learning model address different learning styles. Problem-based learning improves knowledge retention, critical decision making, and communication. These modalities are preferred by learners and contribute to their engagement, in turn leading to durable learning. Follow-up after live events is warranted through spaced education strategies. The objectives of this article are to (1) summarize and illustrate the implementation of experiential learning theory for bronchoscopy courses, (2) discuss the flipped classroom model and problem-based learning, (3) illustrate bronchoscopy checklists implementation in simulation, and (4) discuss the importance of feedback and spaced learning for bronchoscopy education programs...
March 2018: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/29432806/characterization-of-lipid-metabolism-genes-and-the-influence-of-fatty-acid-supplementation-in-the-hepatic-lipid-metabolism-of-dusky-grouper-epinephelus-marginatus
#10
Bruno C Araújo, Nicholas M Wade, Paulo H de Mello, Jandyr de A Rodrigues-Filho, Carlos E O Garcia, Mariana F de Campos, Natasha A Botwright, Diogo T Hashimoto, Renata G Moreira
Dusky grouper is an important commercial fish species in many countries, but some factors such as overfishing has significantly reduced their natural stocks. Aquaculture emerges as a unique way to conserve this species, but very little biological information is available, limiting the production of this endangered species. To understand and generate more knowledge about this species, liver transcriptome sequencing and de novo assembly was performed for E. marginatus by Next Generation Sequencing (NGS). Sequences obtained were used as a tool to validate the presence of key genes relevant to lipid metabolism, and their expression was quantified by qPCR...
February 9, 2018: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/29432624/same-content-different-methods-comparing-lecture-engaged-classroom-and-simulation
#11
Meghan F Raleigh, Garland Anthony Wilson, David Alan Moss, Kristen A Reineke-Piper, Jeffrey Walden, Daniel J Fisher, Tracy Williams, Christienne Alexander, Brock Niceler, Anthony J Viera, Todd Zakrajsek
BACKGROUND AND OBJECTIVES: There is a push to use classroom technology and active teaching methods to replace didactic lectures as the most prevalent format for resident education. This multisite collaborative cohort study involving nine residency programs across the United States compared a standard slide-based didactic lecture, a facilitated group discussion via an engaged classroom, and a high-fidelity, hands-on simulation scenario for teaching the topic of acute dyspnea. The primary outcome was knowledge retention at 2 to 4 weeks...
February 2018: Family Medicine
https://www.readbyqxmd.com/read/29432081/retention-of-student-pharmacists-knowledge-and-skills-regarding-overdose-management-with-naloxone
#12
Anita N Jacobson, Jeffrey P Bratberg, Miranda Monk, John Ferrentino
BACKGROUND: Overdose education and naloxone training was recently implemented into the required curriculum of the College of Pharmacy at the University of Rhode Island. The objective of this study was to compare the retention of knowledge between student pharmacists who received a didactic lecture only versus student pharmacists who received the same lecture plus a skills-based objective structured clinical examination (OSCE) with a standardized patient actor. METHODS: Students in their first-professional year (P1) of the Doctor of Pharmacy program (n = 129) and students in their second-professional (P2) year (n = 123) attended a required lecture on opioid overdose, including detailed naloxone training...
February 12, 2018: Substance Abuse
https://www.readbyqxmd.com/read/29426816/feasibility-and-efficacy-of%C3%A2-a-parent-focused-text-message-delivered-intervention-to%C3%A2-reduce-sedentary-behavior-in-2-to-4-year-old-children-mini-movers-pilot-randomized-controlled-trial
#13
Katherine L Downing, Jo Salmon, Trina Hinkley, Jill A Hnatiuk, Kylie D Hesketh
BACKGROUND: Despite public health guidelines to limit sedentary behavior, many young children spend large amounts of time sedentary (eg, screen and sitting time) during waking hours. OBJECTIVE: The objective of this study was to test the feasibility and efficacy of a parent-focused, predominantly text message-delivered intervention to support parents to reduce the amount of time their children spend in sedentary behavior. METHODS: Mini Movers was a pilot randomized controlled trial delivered to parents of 2- to 4-year-old children in Melbourne, Australia...
February 9, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29424086/circadian-processes-in-the-rna-life-cycle
#14
REVIEW
Manon Torres, Denis Becquet, Jean-Louis Franc, Anne-Marie François-Bellan
The circadian clock drives daily rhythms of multiple physiological processes, allowing organisms to anticipate and adjust to periodic changes in environmental conditions. These physiological rhythms are associated with robust oscillations in the expression of at least 30% of expressed genes. While the ability for the endogenous timekeeping system to generate a 24-hr cycle is a cell-autonomous mechanism based on negative autoregulatory feedback loops of transcription and translation involving core-clock genes and their protein products, it is now increasingly evident that additional mechanisms also govern the circadian oscillations of clock-controlled genes...
February 9, 2018: Wiley Interdisciplinary Reviews. RNA
https://www.readbyqxmd.com/read/29421673/n-doped-carbon-coated-anatase-tio2-nanoparticles-as-superior-na-ion-battery-anodes
#15
Jin Wang, Guiyu Liu, Kaili Fan, Dan Zhao, Beibei Liu, Jianbo Jiang, Dong Qian, Chunming Yang, Junhua Li
N-doped carbon coated TiO2 nanoparticles (TiO2@NC) were synthesized through a simple two-step route, in which dopamine was simultaneously utilized as both nitrogen and carbon sources. With TiO2@NC applied in the Na-ion battery (SIB) anodes, the continuous and uniform N-doped carbon layer can not only enhance the electrical conductivity of TiO2 and facilitate the surface pseudocapacitive process, but also serve as a buffer layer to accommodate the volume expansion during the sodiation-desodiation processes. The as-prepared TiO2@NC exhibits excellent electrochemical performance when utilized as the SIB anodes, which delivers a remarkably high reversible capacity of 250...
February 2, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29409417/the-hand-surgeon-consultation-improves-patient-knowledge-in-a-hand-surgery-mission-to-honduras
#16
Marc E Walker, Carolyn Chuang, Craig R Moores, Matthew L Webb, Samuel D Buonocore, J Grant Thomson
BACKGROUND: The purpose of this study was to assess impact of the surgeon consultation and informed consent process on patient education in an international hand surgery mission compared with a US academic hand surgery practice. These two groups were selected to evaluate communication difficulties in a surgical mission setting compared with standard of care in a high-income country. METHODS: A multi-part survey was administered to patients presenting to a hand surgery mission during March 2012 and new patients of a university hand center in a 3-month period during 2011...
March 2018: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29407939/role-development-of-community-health-workers-for-cardiovascular-disease-prevention-in-india
#17
Aditya Khetan, Toral Patel, Vittal Hejjaji, Dweep Barbhaya, Sri Krishna Madan Mohan, Richard Josephson, Allison Webel
Cardiovascular disease (CVD) is the leading cause of mortality in India. Since community health workers (CHWs) have historically played a pivotal role in improving maternal and child health, it has been hypothesized that they have the potential to mitigate the impact of CVD in countries such as India. Project SEHAT is a cluster RCT to test the hypothesis that CHWs can improve the control of cardiovascular risk factors in a community in West Bengal, India. This study sought to quantitatively assess the training outcomes of CHWs recruited for Project SEHAT, and qualitatively assess their recruitment, training and fieldwork experiences...
January 17, 2018: Evaluation and Program Planning
https://www.readbyqxmd.com/read/29407261/evaluation-of-strategies-designed-to-enhance-student-engagement-and-success-of-indigenous-midwifery-students-in-an-away-from-base-bachelor-of-midwifery-program-in-australia-a-qualitative-research-study
#18
Paula M Schulz, Carmel L Dunne, Denise Burdett-Jones, Natalie S Gamble, Machellee M Kosiak, Joclyn M Neal, Gail E Baker
BACKGROUND: A strategy to close the gap in relation to Indigenous health is the employment of more Indigenous health professionals. However, despite government reviews, research studies and educational initiatives, Indigenous students' retention and completion rates of tertiary education remains below those of non-Indigenous Australians. OBJECTIVE: To evaluate two enhancements to an Away-from-Base Bachelor of Midwifery program for Indigenous students, namely the appointment of an Indigenous Academic Liaison Midwife to provide academic and cultural support and an additional clinical placement in a high-volume tertiary hospital...
January 31, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29406814/a-randomized-controlled-trial-of-video-education-versus-skill-demonstration-which-is-more-effective-in-teaching-sterile-surgical-technique
#19
Stephanie N Pilieci, Saad Y Salim, Daithi S Heffernan, Kamal M F Itani, Rachel G Khadaroo
BACKGROUND: Video education has many advantages over traditional education including efficiency, convenience, and individualized learning. Learning sterile surgical technique (SST) is imperative for medical students, because proper technique helps prevent surgical site infections (SSIs). We hypothesize that video education is at least as effective as traditional skill demonstration in teaching first-year medical students SST. METHODS: A video series was created to demonstrate SST ( https://www...
February 6, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29401332/augmenting-fellow-education-through-spaced-multiple-choice-questions
#20
Alice E Barsoumian, Heather C Yun
Background: The San Antonio Uniformed Services Health Education Consortium Infectious Disease Fellowship program historically included a monthly short-answer and multiple-choice quiz. The intent was to ensure medical knowledge in relevant content areas that may not be addressed through clinical rotations, such as operationally relevant infectious disease. After completion, it was discussed in a small group with faculty. Over time, faculty noted increasing dissatisfaction with the activity...
January 1, 2018: Military Medicine
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