keyword
MENU ▼
Read by QxMD icon Read
search

Knowledge Retention

keyword
https://www.readbyqxmd.com/read/28643517/a-novel-strategy-for-comprehensive-profiling-and-identification-of-acidic-glycosphingolipids-using-ultra-high-performance-liquid-chromatography-coupled-with-quadrupole-time-of-flight-mass-spectrometry
#1
Ting Hu, Zhixin Jia, Jinlan Zhang
Acidic glycosphingolipids (AGSLs), which mainly consist of ganglioside and sulfatide moieties, are highly concentrated in the central nervous system. Comprehensive profiling of AGSLs has historically been challenging because of their high complexity and the lack of standards. In this paper, a novel strategy was developed to comprehensively profile AGSLs using ultra-high-performance liquid chromatography-quadrupole time of flight mass spectrometry (UPLC-Q-TOF-MS). Ganglioside isomers with different glycan chains such as GD1a/ GD1b were completely separated on a C18 column for the first time to our knowledge, facilitated by the addition of formic acid in the mobile phase...
June 23, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28641225/investigation-of-dissociation-constants-for-individual-and-total-naphthenic-acids-species-using-ultra-performance-liquid-chromatography-ion-mobility-time-of-flight-mass-spectrometry-analysis
#2
Rongfu Huang, Pamela Chelme-Ayala, Yanyan Zhang, Mohamed Changalov, Mohamed Gamal El-Din
Ultra-performance liquid chromatography ion mobility time-of-flight mass spectrometry (UPLC-IM-TOFMS) was utilized for the analysis of naphthenic acids (NAs) in fractions of pH-dependent sequential liquid-liquid extractions from oil sands process-affected water. Ion-mobility separation technique allowed the differentiation of OyS-NAs (2 ≤ y ≤ 4) from Ox-NAs (2 ≤ x ≤ 5) via drift time versus retention time separations. The results indicated that the addition of S atom to the O2-NA molecule led to a lower increase in the dissociation constant (pKa) compared to that caused by the addition of O atom...
June 18, 2017: Chemosphere
https://www.readbyqxmd.com/read/28635480/leadership-styles-in-nursing
#3
Vicki Cope, Melanie Murray
Nurses are often asked to think about leadership, particularly in times of rapid change in healthcare, and where questions have been raised about whether leaders and managers have adequate insight into the requirements of care. This article discusses several leadership styles relevant to contemporary healthcare and nursing practice. Nurses who are aware of leadership styles may find this knowledge useful in maintaining a cohesive working environment. Leadership knowledge and skills can be improved through training, where, rather than having to undertake formal leadership roles without adequate preparation, nurses are able to learn, nurture, model and develop effective leadership behaviours, ultimately improving nursing staff retention and enhancing the delivery of safe and effective care...
June 21, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28633832/effects-of-ultrasound-on-the-beef-structure-and-water-distribution-during-curing-through-protein-degradation-and-modification
#4
Da-Cheng Kang, Xue-Qin Gao, Qing-Feng Ge, Guang-Hong Zhou, Wan-Gang Zhang
The objective of this study was to explore the mechanisms of power ultrasound (PUS, 150 and 300W) and treatment time (30 and 120min) on the water-holding capacity (WHC) and tenderness of beef during curing. Beef muscle at 48h post mortem was subjected to PUS treatment at a frequency of 20kHz. Analysis of compression loss and shear force showed that PUS-assisted curing significantly increased the WHC and the tenderness of beef compared to static brining (p<0.05). According to the analysis of LF-NMR, PUS treatment could increase the P21 values which indicated an improvement in water-binding ability of beef muscle...
September 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28628812/modelling-water-and-nutrient-fluxes-in-the-danube-river-basin-with-swat
#5
REVIEW
Anna Malagó, Faycal Bouraoui, Olga Vigiak, Bruna Grizzetti, Marco Pastori
This study provides an innovative process-based modelling approach using the SWAT model and shows its application to support the implementation of the European environmental policies in large river basins. The approach involves several pioneering modelling aspects: the inclusion of current management practices; an innovative calibration and validation methodology of streamflow and water quality; a sequential calibration starting from crop yields, followed by streamflow and nutrients; and the use of concentrations instead of loads in the calibration...
June 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28627929/design-of-the-hptn-065-tlc-plus-study-a-study-to-evaluate-the-feasibility-of-an-enhanced-test-link-to-care-plus-treat-approach-for-hiv-prevention-in-the-united-states
#6
Theresa Gamble, Bernard Branson, Deborah Donnell, H Irene Hall, Georgette King, Blayne Cutler, Shannon Hader, David Burns, Jason Leider, Angela Fulwood Wood, Kevin G Volpp, Kate Buchacz, Wafaa M El-Sadr
Background/Aims HIV continues to be a major public health threat in the United States, and mathematical modeling has demonstrated that the universal effective use of antiretroviral therapy among all HIV-positive individuals (i.e. the "test and treat" approach) has the potential to control HIV. However, to accomplish this, all the steps that define the HIV care continuum must be achieved at high levels, including HIV testing and diagnosis, linkage to and retention in clinical care, antiretroviral medication initiation, and adherence to achieve and maintain viral suppression...
June 1, 2017: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/28626487/identification-of-the-chemical-constituents-in-simiao-wan-and-rat-plasma-after-oral-administration-by-gc-ms-and-lc-ms
#7
Yunshuang Fan, Yamei Li, Yuanyuan Wu, Lixin Li, Yuming Wang, Yubo Li
Simiao Wan (SMW), an important multiherbal formula used in traditional Chinese medicine, is extensively used to treat rheumatoid arthritis. However, the knowledge of the bioactive components of SMW remains unclear. Thus, gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) were used to analyze the chemical constituents of volatile and nonvolatile extracts of SMW, as well as its absorbed components in rat plasma after oral SMW administration. Identification of several compounds was enabled by comparison of retention times, MS spectra, and MS/MS spectral data with the standard substance and reference materials reported in the literature...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28624983/how-to-increase-vaccination-acceptance-among-apostolic-communities-quantitative-results-from-an-assessment-in-three-provinces-in-zimbabwe
#8
Regina Gerede, Zorodzai Machekanyanga, Serigne Ndiaye, Kenneth Chindedza, Colline Chigodo, Messeret E Shibeshi, James Goodson, Fussum Daniel, Reinhard Kaiser
A worldwide increasing trend toward vaccine hesitancy has been reported. Measles outbreaks in southern Africa in 2009-2010 were linked to objections originating from Apostolic gatherings. Founded in Zimbabwe in the 1950s, the Apostolic church has built up a large number of followers with an estimated 3.5 million in Zimbabwe in 2014. To inform planning of interventions for the 2015 measles-rubella vaccination campaign, we assessed vaccination status and knowledge, attitudes and practices among purposive samples of Apostolic caregivers in three districts each in Harare City, Manicaland and Matabeleland South in Zimbabwe...
June 17, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28624163/simultaneous-congenital-mucocoele-of-the-blandin-n%C3%A3-hn-glands-and-teratoma-of-the-tongue-early-management-and-follow-up-at-one-year
#9
Nathalie Pham Dang, Anne-Claire Melka, Hélène Laurichesse Delmas, Isabelle Barthélémy
Mucocoele of the Blandin-Nühn glands and teratomas of the tongue are rare in newborn babies. We present what is to our knowledge the first documented case of both at the same time, and describe management and follow up over 12 months after the birth. Prenatal diagnosis defined the treatment plan during delivery to establish an airway for the baby promptly. A normal delivery is possible if the cyst is anterior, and can be punctured during delivery. Delayed excision reduces the possibility of oedema and obstruction of the airway, ensures complete resection, avoids recurrence, and confirms the diagnosis...
June 14, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28622034/the-experiences-of-newly-diagnosed-men-who-have-sex-with-men-entering-the-hiv-care-cascade-in-lima-peru-2015-2016-a-qualitative-analysis-of-counselor-participant-text-message-exchanges
#10
Erik Bayona, Luis Menacho, Eddy R Segura, Gitau Mburu, Fernando Roman, Consuelo Tristan, Elizabeth Bromley, Robinson Cabello
Mobile phone technology (mHealth) is a promising tool that has been used to improve HIV care in high-risk populations worldwide. Understanding patient perspectives of newly diagnosed men who have sex with men (MSM) in Lima, Peru during linkage and engagement in the HIV care continuum can help close the gaps in care following initial HIV diagnosis and ensure retention in continuous care. From June 2015 to March 2016, as part of a randomized controlled trial, 40 MSM participants were linked to care with an mHealth intervention within 3 months of HIV diagnosis at Via Libre clinic...
June 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28618208/experiences-of-registered-nurses-transitioning-from-employment-in-acute-care-to-primary-health-care-quantitative-findings-from-a-mixed-methods-study
#11
Christine Ashley, Elizabeth Halcomb, Angela Brown, Kath Peters
AIM: To describe the experiences of registered nurses who transition from acute to primary health care (PHC) employment. BACKGROUND: Internationally the provision of health care in PHC settings is increasing. Nurses are moving from acute care employment to meet the growing demand for a PHC workforce. However, little is known about the transition experiences of these nurses. DESIGN: A sequential mixed methods study comprising a survey, and semi-structured interviews...
June 15, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28614997/resilience-based-diabetes-self-management-education-perspectives-from-african-american-participants-community-leaders-and-healthcare-providers
#12
H Matthew Lehrer, Susan K Dubois, Sharon A Brown, Mary A Steinhardt
Purpose The purpose of this qualitative, focus group study was to further refine the Resilience-Based Diabetes Self-Management Education (RB-DSME) recruitment process and intervention, build greater trust in the community, and identify strategies to enhance its sustainability as a community-based intervention in African American church settings. Methods Six 2-hour focus groups (N = 55; 10 men and 45 women) were led by a trained moderator with a written guide to facilitate discussion. Two sessions were conducted with individuals diagnosed with type 2 diabetes mellitus (T2DM) who participated in previous RB-DSME pilot interventions and their family members, two sessions with local church leaders, and two sessions with community healthcare providers who care for patients with T2DM...
June 1, 2017: Diabetes Educator
https://www.readbyqxmd.com/read/28613257/dissemination-of-chronic-disease-self-management-education-cdsme-programs-in-the-united-states-intervention-delivery-by-rurality
#13
Matthew Lee Smith, Samuel D Towne, Angelica Herrera-Venson, Kathleen Cameron, Kristie P Kulinski, Kate Lorig, Scott A Horel, Marcia G Ory
Background: Alongside the dramatic increase of older adults in the United States (U.S.), it is projected that the aging population residing in rural areas will continue to grow. As the prevalence of chronic diseases and multiple chronic conditions among adults continues to rise, there is additional need for evidence-based interventions to assist the aging population to improve lifestyle behaviors, and self-manage their chronic conditions. The purpose of this descriptive study was to identify the geospatial dissemination of Chronic Disease Self-Management Education (CDSME) Programs across the U...
June 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28610893/an-insight-into-the-molecular-mechanism-of-the-temporary-enhancement-effect-of-isopulegol-decanoate-on-the-skin
#14
Xiaochang Liu, Meiying Liu, Chao Liu, Peng Quan, Yongshan Zhao, Liang Fang
Chemical enhancers are widely used to facilitate drug permeation in transdermal drug delivery system (TDDS) and the effect of chemical enhancers is desired to be temporary. Though temporary enhancement effect of chemical enhancers has been widely discussed, there is still a lack of knowledge about the molecular mechanism of temporary enhancement effect. Using the skin permeation of flurbiprofen as a probe, the temporary enhancement effect of isopulegol decanoate (ISO-10) was evaluated with in vitro permeation experiment and confocal laser scanning microscopy (CLSM)...
June 10, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28604555/immune-related-neurological-symptoms-in-an-adolescent-patient-receiving-the-checkpoint-inhibitor-nivolumab
#15
Dmitry Tchapyjnikov, Alexandra J Borst
Immune checkpoint inhibitors are a novel group of immunotherapeutic agents for the treatment of cancer. Immune-related adverse events, including neurological symptoms, have been associated with these agents. We present the case of an adolescent with refractory Hodgkin lymphoma treated with nivolumab, a PD1 inhibitor, who developed Hashimoto thyroiditis, posterior reversible encephalopathy syndrome causing seizures, as well as urinary retention, truncal/appendicular spasticity, dysphagia, and a progressive encephalopathy that was clinically consistent with a diagnosis of progressive encephalopathy with rigidity and myoclonus, a stiff-person-syndrome spectrum disorder...
June 9, 2017: Journal of Immunotherapy
https://www.readbyqxmd.com/read/28604262/current-evidence-on-the-socket-shield-technique-a-systematic-review
#16
Amit Srikant Gharpure, Neel B Bhatavadekar
The recently popularised socket-shield technique involves intentional retention of a section of the remnant root at the time of immediate implant placement to preserve the buccal/proximal bone from resorption. The objective of this systematic review was to assess the literature available on the socket-shield technique and weigh its biological plausibility and long-term clinical prognosis. A Systematic Search was performed in PubMed-Medline, Embase, Web of Knowledge, Google Scholar and Cochrane Central for clinical/ animal studies up to April 2017...
June 12, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28602999/cough-and-bronchiectasis
#17
REVIEW
Paul McCallion, Anthony De Soyza
Bronchiectasis is a chronic lung disease with permanent airway dilatation, mucus retention and recurrent lower respiratory tract infections. Bronchiectasis is increasing in prevalence and has a significant morbidity and an excess mortality rate over age matched controls. It is increasingly identified during investigations into chronic cough and is evident high resolution CT scanning. There remain significant knowledge gaps in our understanding of the epidemiology, pathophysiology, prognosis and optimal treatments in bronchiectasis...
June 7, 2017: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28599762/co-teaching-exploring-an-alternative-for-integrated-curriculum
#18
Sadhana Sharma, Ravikirti, Asgar Ali, Roshan Takhelmayum, Mala Mahto, Rathish Nair
PURPOSE: Currently, the curriculum of medical education is compartmentalized which makes achieving the expected outcome, a real challenge. Co-teaching, an existing concept in education, however, may be used in medical education for integrating the applied component while basic concepts are being taught. The hypothesis, "can co-teaching be an alternate for an integrated curriculum?" was explored in this study. Therefore, the present study was designed to compare the outcomes of co-teaching with the existing teaching methodology owing to the absence of integrated curriculum...
July 2017: Journal of the National Medical Association
https://www.readbyqxmd.com/read/28598249/recall-and-decay-of-consent-information-among-parents-of-infants-participating-in-a-randomized-controlled-clinical-trial-using-an-audio-visual-tool-in-the-gambia
#19
Robert B Mboizi, Muhammed O Afolabi, Michael Okoye, Beate Kampmann, Anna Roca, Olubukola T Idoko
Communicating essential research information to low literacy research participants in Africa is highly challenging, since this population is vulnerable to poor comprehension of consent information. Several supportive materials have been developed to aid participant comprehension in these settings. Within the framework of a pneumococcal vaccine trial in The Gambia, we evaluated the recall and decay of consent information during the trial which used an audio-visual tool called 'Speaking Book', to foster comprehension among parents of participating infants...
June 9, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28597072/normal-and-altered-pre-mrna-processing-in-the-dmd-gene
#20
REVIEW
Sylvie Tuffery-Giraud, Julie Miro, Michel Koenig, Mireille Claustres
Splicing of pre-mRNA is a crucial regulatory stage in the pathway of gene expression controlled by multiple post- and co-transcriptional mechanisms. The large Duchenne muscular dystrophy gene encoding the protein dystrophin provides a striking example of the complexity of human pre-mRNAs. In this review, we summarize the current state of knowledge about canonical and non-canonical splicing in the DMD pre-mRNA, with a focus on mechanisms that take place in the full-length transcript isoform expressed in human skeletal muscle...
June 9, 2017: Human Genetics
keyword
keyword
92976
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"