keyword
MENU ▼
Read by QxMD icon Read
search

intradiscal

keyword
https://www.readbyqxmd.com/read/28191592/what-is-the-clinical-evidence-on-regenerative-medicine-in-intervertebral-disc-degeneration
#1
REVIEW
M Basso, L Cavagnaro, A Zanirato, S Divano, C Formica, M Formica, L Felli
PURPOSE: This review aims to explore and summarize the current clinical evidence about the use of regenerative medicine such as mesenchymal stem cells or platelet-rich plasma in intervertebral disc regeneration, in order to clarify the state of art of these novel approaches. MATERIALS AND METHODS: We performed a research of the available literature about regenerative medicine strategies aiming to prevent intervertebral disc degeneration. All preclinical trials and in vitro studies were excluded...
February 13, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28186832/a-comprehensive-review-of-pulsed-radiofrequency-in-the-treatment-of-pain-associated-with-different-spinal-conditions
#2
Giancarlo Facchini, Paolo Spinnato, Giuseppe Guglielmi, Ugo Albisinni, Alberto Bazzocchi
OBJECTIVE: The objective of this review is to evaluate the efficacy of Pulsed Radiofrequency (PRF) treatment of pain associated with different spinal conditions. The mechanisms of action and biological effects are shortly discussed to provide the scientific basis for this radiofrequency modality. METHODS: We systematically searched for clinical studies on spinal clinical conditions using PRF. We searched the MEDLINE (PubMed) database. We classified the information in one table focusing on RCTs and other type of studies...
February 10, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28171773/cervical-traction-therapy-with-and-without-neck-support-a-finite-element-analysis
#3
Kuan Wang, Huihao Wang, Zhen Deng, Zhengyan Li, Hongsheng Zhan, Wenxin Niu
BACKGROUND: Cervical traction is commonly used for treating neck pain. However, few studies have investigated the biomechanical impact such traction has on soft tissues. OBJECTIVES: To analyze the biomechanics of cervical traction therapy in a supine position with and without neck support (NS and non-NS). METHODS: A finite element model of the cervical spine was constructed to investigate the mechanism behind cervical traction therapy. An axial traction force of 100-N was loaded on the upper surface of C0 to simulate traction weight...
January 16, 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28167249/how-are-adjacent-spinal-levels-affected-by-vertebral-fracture-and-by-vertebroplasty-a-biomechanical-study-on-cadaveric-spines
#4
Jin Luo, Deborah J Annesley-Williams, Michael A Adams, Patricia Dolan
BACKGROUND CONTEXT: Spinal injuries and surgery may have important effects at neighbouring spinal levels, but previous investigations of adjacent-level biomechanics have produced conflicting results. We use 'stress profilometry' and non-contact strain measurements to investigate thoroughly this long-standing problem. PURPOSE: To determine how vertebral fracture and vertebroplasty affect compressive load-sharing and vertebral deformations at adjacent spinal levels...
February 3, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28112142/transient-cortical-blindness-after-intradiscal-oxygen-ozone-therapy
#5
Agostino Salvatore Vaiano, Cristiana Valente, Giacomo De Benedetti, Guido Caramello
A 54-year-old caucasian male developed bilateral blindness during an oxygen-ozone injection for disc herniation. The visual loss (VL) was immediately followed by severe frontal headache, vomiting, and nausea. The patient underestimated the VL showing Anton's syndrome, with a complete visual recovery after 2-month follow-up. Magnetic resonance data were consistent with recent ischemic lesions in bilateral vascular territories of posterior cerebral arteries.
December 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28108405/defects-of-the-vertebral-endplate-implications-for-disc-degeneration-depend-on-size
#6
Uruj Zehra, Luke Flower, Katharine Robson-Brown, Michael A Adams, Patricia Dolan
BACKGROUND CONTEXT: Bony vertebral endplates must be porous to allow metabolite transport into the disc, and yet strong to resist high intradiscal pressure. Endplate defects may therefore have nutritional and mechanical consequences for the disc, depending on their size and type. We hypothesise that broad, diffuse defects are more closely associated with disc decompression and degeneration than are focal Schmorl's node-type defects. PURPOSE: To determine how the size and type of endplate defects are related to decompression and degeneration in the adjacent intervertebral disc...
January 17, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28086781/effects-of-the-intradiscal-implantation-of-stromal-vascular-fraction-plus-platelet-rich-plasma-in-patients-with-degenerative-disc-disease
#7
Comella Kristin, Silbert Robert, Parlo Michelle
BACKGROUND: Stromal vascular fraction (SVF) can easily be obtained from a mini-lipoaspirate procedure of fat tissue and platelet rich plasma (PRP) can be obtained from peripheral blood. The SVF contains a mixture of cells including ADSCs and growth factors and has been depleted of the adipocyte (fat cell) population. We evaluated the safety and efficacy of administering SVF and PRP intra-discally into patients with degenerative disc disease. METHODS: A total of 15 patients underwent a local tumescent liposuction procedure to remove approximately 60 ml of fat tissue...
January 13, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28064297/a-clinical-audit-of-interventional-pain-procedures-performed-as-part-of-the-newly-initiated-pain-service-in-a-local-neurosurgical-centre
#8
H C Khoo, B H Soon, A S Jaafar, A Abu Bakar, F Fadzil, K Palaniandy, S Paramasvaran, Y C Choy, C J Toh
Interventional Pain Procedures (IPPs) is a relatively new treatment modality for chronic pain in Malaysia. The Interventional Pain Service (IPS) newly set up in our institution is led by a pain neurosurgeon and provides a whole package of multimodal pain management including different range of IPPs. This clinical audit is to examine the quality of IPPs performed within the IPS in our institution since its initiation. A total of 87 IPPs were performed on 56 chronic pain patients over 3-year duration. As high as 81...
October 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28061487/thermal-induced-osteonecrosis-of-adjacent-vertebra-after-intradiscal-electrothermal-therapy
#9
Soonjoon Kim, Sun-Ho Lee, Eun-Sang Kim, Whan Eoh
A 42-year-old man was admitted to our hospital with complaints of low back pain and intermittent right thigh pain. Twelve weeks before admission, the patient received intradiscal electrothermal therapy (IDET) at a local hospital. The patient still reported low back pain after the procedure that was managed with narcotic analgesics. Follow-up magnetic resonance imaging (MRI) was performed, and his referring physician thought the likely diagnosis was spondylodiscitis at the L4-5 spinal segment with a small epidural abscess...
January 1, 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28050544/influence-of-mononuclear-cell-therapy-on-disc-degeneration-in-rabbits
#10
Rodrigo Caldonazzo Fávaro, André de Oliveira Arruda, Luiz Roberto Gomes Vialle, Emiliano Neves Vialle
OBJECTIVE: The objective of this research was to evaluate the influence of autologous mononuclear stem cells injections on histological changes of collagen in the fibrous annulus of the intervertebral disk after experimental injury. METHODS: 32 New Zealand rabbits were submitted to intervertebral disk puncture, followed by intradiscal injection of mononuclear cells from the iliac crest versus saline injection in the following time periods: two months after the injury (SC2M and SS2M), two weeks (SC2W and SS2W) immediately after injury (SCCP and SSCP), and without inducing degeneration (SCSP and SSSP)...
November 2016: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28018758/cervical-fracture-subluxation-in-a-patient-with-a-prior-c2-sacrum-fusion-case-report-and-review-of-literature
#11
Yi-Ren Chen, Alvin Y Chan, Kevin K Kumar, Anand Veeravagu
Traumatic injury to an adjacent segment of a previously fused spine is a rare complication of scoliosis surgery. The adjacent spinal segments may be more vulnerable to traumatic fracture or dislocation due to increased strain. We present a patient with prior C2 to sacrum fusion who suffered a C2 fracture/dislocation after falling. A 52-year-old female with a previous C2 to the sacrum fusion for idiopathic scoliosis presented with severe and progressively worsening neck pain after multiple falls. Imaging showed anterior displacement of the C2 vertebral body, fracture of C2, and anterior subluxation of the C1-2 complex on C3...
November 22, 2016: Curēus
https://www.readbyqxmd.com/read/28002345/comparison-of-the-more-than-5-year-clinical-outcomes-of-cervical-disc-arthroplasty-versus-anterior-cervical-discectomy-and-fusion-a-protocol-for-a-systematic-review-and-meta-analysis-of-prospective-randomized-controlled-trials
#12
REVIEW
Min-Min Shao, Chun-Hui Chen, Zhong-Ke Lin, Xiang-Yang Wang, Qi-Shan Huang, Yong-Long Chi, Ai-Min Wu
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) was almost the "golden standard" technique in treatment of symptomatic cervical degenerative disc disease, however, it cause motion loss of the indexed level, increase the intradiscal pressure and motion of the adjacent levels, and may accelerate the degeneration of adjacent level. Cervical disc arthroplasty (CDA) was designed to preserve the motion of index level, avoid the over-activity of adjacent levels and reduce the degeneration of adjacent disc levels, the process of degeneration of adjacent level is very slowly, long term follow up studies should be conducted, this study aim to compare the more than 5 years' long-term clinical outcomes and safety between CDA and ACDF...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27982763/effects-of-intradiscal-vacuum-phenomenon-on-surgical-outcome-of-lateral-interbody-fusion-for-degenerative-lumbar-disease
#13
Chun-Po Yen, Joshua M Beckman, Andrew C Vivas, Konrad Bach, Juan S Uribe
OBJECTIVE The authors investigated whether the presence of intradiscal vacuum phenomenon (IVP) results in greater correction of disc height and restoration of segmental lordosis (SL). METHODS A retrospective chart review was performed on every patient at the University of South Florida's Department of Neurosurgery treated with lateral lumbar interbody fusion between 2011 and 2015. From these charts, preoperative plain radiographs and CT images were reviewed for the presence of IVP. Preoperative and postoperative posterior disc height (PDH), anterior disc height (ADH), and SL were measured at disc levels with IVP and compared with those at disc levels without IVP using the t-test...
December 16, 2016: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/27943659/the-fabrication-and-characterization-of-a-multi-laminate-angle-ply-collagen-patch-for-annulus-fibrosus-repair
#14
Rachel McGuire, Ryan Borem, Jeremy Mercuri
One major limitation of intervertebral disc (IVD) repair is that no ideal biomaterial has been developed that effectively mimics the angle-ply collagen architecture and mechanical properties of the native annulus fibrosus (AF). Furthermore, it would be beneficial to devise a simple, scalable process by which to manufacture a biomimetic biomaterial that could function as a mechanical repair patch to be secured over a large defect in the outer AF that will support AF tissue regeneration. Such a biomaterial would: (1) enable the employment of early-stage interventional strategies to treat IVD degeneration (i...
December 12, 2016: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/27935769/fluoroscopically-guided-epidural-injections-of-the-cervical-and-lumbar-spine
#15
Euddeum Shim, Joon Woo Lee, Eugene Lee, Joong Mo Ahn, Yusuhn Kang, Heung Sik Kang
Advances in imaging and the development of injection techniques have enabled spinal intervention to become an important tool in managing chronic spinal pain. Epidural steroid injection (ESI) is one of the most widely used spinal interventions; it directly delivers drugs into the epidural space to relieve pain originating from degenerative spine disorders-central canal stenoses and neural foraminal stenoses-or disk herniations. Knowledge of the normal anatomy of the epidural space is essential to perform an effective and safe ESI and to recognize possible complications...
December 9, 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/27918892/the-effects-of-muscle-weakness-on-degenerative-spondylolisthesis-a-finite-element-study
#16
Rui Zhu, Wen-Xin Niu, Zhi-Li Zeng, Jian-Hua Tong, Zhi-Wei Zhen, Shuang Zhou, Yan Yu, Li-Ming Cheng
BACKGROUND: Whether muscle weakness is a cause, or result, of degenerative spondylolisthesis is not currently well understood. Little biomechanical evidence is available to offer an explanation for the mechanism behind exercise therapy. Therefore, the aim of this study is to investigate the effects of back muscle weakness on degenerative spondylolisthesis and to tease out the biomechanical mechanism of exercise therapy. METHODS: A nonlinear 3-D finite element model of L3-L5 was constructed...
November 26, 2016: Clinical Biomechanics
https://www.readbyqxmd.com/read/27909655/adjacent-disc-height-reduction-and-clinical-outcome-after-intradiscal-cement-leakage
#17
Minjie Shen, Junjie Niu, Haifei Zhou, Qian Meng, Minfeng Gan, Huilin Yang
OBJECTIVE: The purpose of this study is to evaluate the effect of intradiscal cement leakage on the height of adjacent cement-containing discs and the resulting clinical efficacy after kyphoplasty. METHODS: A total of 124 patients were included and classified into two groups: group A included 20 patients with intradiscal leakage, and group B contained 104 patients without intradiscal leakage. The mean follow-up time was 20.56±3.51 months. The height of the corresponding discs in both groups was measured using Farfan's method...
2016: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/27906950/clinical-evaluation-and-magnetic-resonance-imaging-assessment-of-intradiscal-methylene-blue-injection-for-the-treatment-of-discogenic-low-back-pain
#18
XiaoJun Zhang, Jie Hao, Zhenming Hu, HaiTao Yang
BACKGROUND: Low back pain is a common worldwide health problem and has a significant socioeconomic impact on public health. Internal disc disruption has been considered as the most common cause of low back pain. Various therapies, including interbody fusion, disc replacement, injection therapies, and thermal annular procedures have been utilized for the treatment of discogenic low back pain. Recently, a new method of intradiscal methylene blue injection has been introduced to treat discogenic low back pain, but the clinical outcomes are controversial...
November 2016: Pain Physician
https://www.readbyqxmd.com/read/27891035/intradiscal-and-intra-articular-facet-infiltrations-with-plasma-rich-in-growth-factors-reduce-pain-in-patients-with-chronic-low-back-pain
#19
Fernando Kirchner, Eduardo Anitua
CONTEXT: Low back pain (LBP) is a complex and disabling condition, and its treatment becomes a challenge. AIMS: The aim of our study was to assess the clinical outcome of plasma rich in growth factors (PRGF-Endoret) infiltrations (one intradiscal, one intra-articular facet, and one transforaminal epidural injection) under fluoroscopic guidance-control in patients with chronic LBP. PRGF-Endoret which has been shown to be an efficient treatment to reduce joint pain...
October 2016: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/27870867/preserving-posterior-complex-can-prevent-adjacent-segment-disease-following-posterior-lumbar-interbody-fusion-surgeries-a-finite-element-analysis
#20
Yun-Peng Huang, Cheng-Fei Du, Cheng-Kung Cheng, Zheng-Cheng Zhong, Xuan-Wei Chen, Gui Wu, Zhe-Cheng Li, Jin-Duo Ye, Jian-Hua Lin, Li Zhen Wang
OBJECTIVE: To investigate the biomechanical effects of the lumbar posterior complex on the adjacent segments after posterior lumbar interbody fusion (PLIF) surgeries. METHODS: A finite element model of the L1-S1 segment was modified to simulate PLIF with total laminectomy (PLIF-LAM) and PLIF with hemilaminectomy (PLIF-HEMI) procedures. The models were subjected to a 400N follower load with a 7.5-N.m moment of flexion, extension, torsion, and lateral bending. The range of motion (ROM), intradiscal pressure (IDP), and ligament force were compared...
2016: PloS One
keyword
keyword
92965
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"