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https://www.readbyqxmd.com/read/29240301/the-terracol-and-ardouin-developmental-model-of-frontal-sinus-drainage-pathway-and-surrounding-spaces-a-radiologic-validation
#1
Marco Ferrari, Alberto Schreiber, Davide Mattavelli, Vittorio Rampinelli, Barbara Buffoli, Marco Ravanelli, Matteo Bettinsoli, Luigi F Rodella, Piero Nicolai
BACKGROUND: The complexity of the frontal sinus drainage pathway (FSDP) can be challenging even for expert surgeons. Several classifications have been proposed to simplify the understanding of FSDP, whose anatomical variability can be simplified based on the knowledge of its developmental mechanisms. METHODS: Cone-beam computed tomography studies performed at the Unit of Radiology of the University of Brescia between March and November 2012 were retrospectively analyzed...
December 14, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29233836/radiomic-features-are-superior-to-conventional-quantitative-computed-tomographic-metrics-to-identify-coronary-plaques-with-napkin-ring-sign
#2
Márton Kolossváry, Júlia Karády, Bálint Szilveszter, Pieter Kitslaar, Udo Hoffmann, Béla Merkely, Pál Maurovich-Horvat
BACKGROUND: Napkin-ring sign (NRS) is an independent prognostic imaging marker of major adverse cardiac events. However, identification of NRS is challenging because of its qualitative nature. Radiomics is the process of extracting thousands of quantitative parameters from medical images to create big-data data sets that can identify distinct patterns in radiological images. Therefore, we sought to determine whether radiomic analysis improves the identification of NRS plaques. METHODS AND RESULTS: From 2674 patients referred to coronary computed tomographic angiography caused by stable chest pain, expert readers identified 30 patients with NRS plaques and matched these with 30 non-NRS plaques with similar degree of calcification, luminal obstruction, localization, and imaging parameters...
December 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29229338/delayed-occurrence-of-diabetes-insipidus-following-transsphenoidal-surgery-with-radiological-evaluation-of-the-pituitary-stalk-on-magnetic-resonance-imaging
#3
Yasuhiko Hayashi, Yasuhiro Aida, Yasuo Sasagawa, Masahiro Oishi, Daisuke Kita, Osamu Tachibana, Fumiaki Ueda, Mitsutoshi Nakada
INTRODUCTION: Diabetes insipidus (DI) is a major complication of transsphenoidal surgery (TSS). DI usually occurs within a couple of days after TSS. Delayed occurrence of postoperative DI is rarely observed and its developing mechanisms remain unknown. Methods Six patients were identified as having postoperative delayed DI, which was defined as DI that first occurred two or more weeks after TSS. They consisted of one male and five females, and their mean age was 38.3 (range: 10-76) years...
December 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29227405/osseous-convexity-at-the-anterior-fontanelle-a-presentation-of-metopic-fusion
#4
Alexander Haosi Sun, John A Persing
BACKGROUND: Craniosynostosis, or a premature fusion of 1 or more cranial vault sutures, results in characteristic head shape deformities. In previous reports, an osseous prominence at the anterior fontanelle has been suggestive of adjacent suture fusion and local elevation in intracranial pressure (ICP). This prominence has been termed the "volcano" sign, and has been described in the anterior fusion of the sagittal suture and serves as an indication for surgery. METHODS: Two patients presented for head shape evaluation with mild metopic ridging and anterior fontanellar osseous convexities consistent with the volcano sign...
December 7, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29224302/-clinical-and-radiological-features-of-adult-patients-with-different-antisynthetase-syndrome-based-on-serum-anti-aminoacyl-trna-synthetase-antibody-type
#5
S Li, H Huang, X Y Song, K Xu, C Y Wu, Q Wang, Z J Xu
Objective: To describe the clinical and radiological characteristics of antisynthetase syndrome associated interstitial lung disease in patients with different serum anti-aminoacyl-tRNA synthetase antibodies. Methods: We conducted a retrospective analysis of 5 adult patients with antisynthetase syndrome associated interstitial lung disease in Peking Union Medical College Hospital. Their clinical and chest radiological data were analyzed and relevant literatures were reviewed. Results: Among these 5 patients, there were 1 male and 4 females, aged from 32 y to 67 y, with a mean age of 53 y...
December 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29223948/-hypersensitivity-pneumonitis-a-series-of-nine-cases-with-surgical-lung-biopsy
#6
Ricardo A Gómez Tejada, Cora G Legarreta, Juan Ignacio Enghelmayer, Milagros Dianti, Silvana Acuña, Gloria Olmedo
In a series of nine patients with histopathological diagnosis of hypersensitivity pneumonitis, we retrospectively evaluated clinical data, exposure related factors, pulmonary function tests and chest computed tomography scans. A restrictive abnormality with reduction of diffusion capacity for carbon monoxide was mainly found. Chest scans showed fibrotic patterns in most cases; ground glass attenuation areas with mosaic pattern and consolidation in the rest. Exposure to avian antigens, cereal grains and air conditioners contaminated with fungi yeasts and bacteria, were suspected from clinical data in two-thirds of the cases...
2017: Medicina
https://www.readbyqxmd.com/read/29223918/postmortem-computed-tomography-findings-in-cases-of-bath-related-death-applicability-and-limitation-in-forensic-practice
#7
Satoko Mishima, Hideto Suzuki, Tatsushige Fukunaga, Yoko Nishitani
PURPOSE: Bath-related deaths occur frequently in Japan, and many of these deaths are diagnosed as death from disease without autopsy in the current Japanese death-investigation system. Therefore, we aimed to examine the postmortem computed tomography (PMCT) findings of bath-related deaths to determine if PMCT can differentiate between real cases of drowning and sudden deaths not related to drowning. METHODS: Bath-related deaths were sampled from all autopsies conducted at the Tokyo Medical Examiner's Office from September 2015 to August 2016...
December 2, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29219788/differential-patterns-of-metastatic-dissemination-across-medulloblastoma-subgroups
#8
Michal Zapotocky, Daddy Mata-Mbemba, David Sumerauer, Petr Liby, Alvaro Lassaletta, Josef Zamecnik, Lenka Krskova, Martin Kyncl, Jan Stary, Suzanne Laughlin, Anthony Arnoldo, Cynthia Hawkins, Uri Tabori, Michael D Taylor, Eric Bouffet, Charles Raybaud, Vijay Ramaswamy
OBJECTIVE Metastatic dissemination is a major treatment challenge and cause of death in patients with medulloblastoma. However, the influence of molecular biology on the pattern of metastatic dissemination at diagnosis is not known. In this study, the authors sought to define the location, pattern, and imaging characteristics of medulloblastoma metastases across subgroups at diagnosis. METHODS A consecutive cohort of patients with metastatic medulloblastoma at The Hospital for Sick Children and the University Hospital Motol, who underwent up-front MRI of the craniospinal axis, was assembled and allocated to subgroups using NanoString limited gene-expression profiling...
December 8, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29217064/the-management-of-vascular-malformations-of-the-airway-natural-history-investigations-medical-surgical-and-radiological-management
#9
REVIEW
Tristan Klosterman, Teresa M O
Vascular malformations may affect nearly all aspects of the upper airway. Each type of malformation has a characteristic pattern of disease. These lesions may be focal or diffuse, and require directed management strategies. Physicians treating these entities should have a high level of suspicion to consider airway evaluation even in the absence of overt symptoms. However, cutaneous head and neck venous malformations or other lesions affecting the lips, oral cavity, or tongue can herald the presence of coexisting airway lesions...
February 2018: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/29214039/clinical-and-genetic-analysis-of-spinocerebellar-ataxia-type-7-sca7-in-zambian-families
#10
Masharip Atadzhanov, Danielle C Smith, Mwila H Mwaba, Omar K Siddiqi, Alan Bryer, L Jacquie Greenberg
Background: To date, 43 types of Spinocerebellar Ataxias (SCAs) have been identified. A subset of the SCAs are caused by the pathogenic expansion of a CAG repeat tract within the corresponding gene. Ethnic and geographic differences are evident in the prevalence of the autosomal dominant SCAs. Few descriptions of the clinical phenotype and molecular genetics of the SCAs are available from the African continent. Established studies mostly concern the South African populations, where there is a high frequency of SCA1, SCA2 and SCA7...
2017: Cerebellum & Ataxias
https://www.readbyqxmd.com/read/29212238/quantification-of-circulating-cell-free-dna-to-predict-patient-survival-in-non-small-cell-lung-cancer
#11
Myung Han Hyun, Jae Sook Sung, Eun Joo Kang, Yoon Ji Choi, Kyong Hwa Park, Sang Won Shin, Sung Yong Lee, Yeul Hong Kim
We used computed tomography (CT) to explore the prognostic value of cell-free (cf) DNA quantification and its predictive efficacy over time after chemotherapy in non-small-cell lung cancer (NSCLC) patients. In total, 177 NSCLC patients were enrolled in a prospective biomarker trial. Consecutive paired blood collection was performed to determine cfDNA concentrations at baseline CT and throughout serial follow-ups. The best cfDNA cut-off value to predict progression-free and overall survival was determined using X-tile analysis...
November 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/29212042/facial-nerve-injury-and-other-complications-following-retromandibular-subparotid-approach-for-the-management-of-condylar-fractures
#12
Stéphane Bruneau, Delphine S Courvoisier, Paolo Scolozzi
PURPOSE: To estimate the prevalence and identify risk factors for facial nerve paralysis (FNP) and other postoperative complications after the use of the retromandibular subparotid approach (RMSA) for the treatment of condylar fractures. MATERIALS AND METHODS: Radiologic and clinical data from all patients who underwent an RMSA from 2007 through 2015 at the University Hospital of Geneva (Geneva, Switzerland) were retrospectively reviewed. The primary and secondary outcome variables were, respectively, FNP and other complications (unesthetic scars, infection, nonunion, malocclusion, salivary fistula, Frey syndrome, and loosening or breaking of plates and screws)...
December 3, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29209518/diagnosis-and-treatment-of-soft-tissue-sarcomas-of-the-extremities-and-trunk
#13
Maria Anna Smolle, Dimosthenis Andreou, Per-Ulf Tunn, Joanna Szkandera, Bernadette Liegl-Atzwanger, Andreas Leithner
The relatively low incidence and often atypical clinical presentation of soft-tissue sarcomas (STS) impedes early and adequate diagnosis. Patients may report on recently enlarged soft-tissue swellings, infrequently complain of painful lesions, or even have no symptoms at all.A thorough diagnostic work-up is essential in order to distinguish between benign soft-tissue tumours and STSs. Patient history, clinical features and radiological findings all help in assessing the underlying pathology. 'Worrying' features such as recent increase in size, deep location relative to the fascia, a tumour exceeding 4 cm in size, and invasive growth patterns seen on imaging should prompt verification by biopsy...
October 2017: EFORT Open Reviews
https://www.readbyqxmd.com/read/29207437/unfavourable-outcome-of-glucocorticoid-treatment-in-suspected-idiopathic-pulmonary-fibrosis
#14
Ivo A Wiertz, Wim A Wuyts, Coline H M van Moorsel, Adriane D M Vorselaars, Hendrik W van Es, Matthijs F M van Oosterhout, Jan C Grutters
BACKGROUND AND OBJECTIVE: The diagnostic classification of 'possible idiopathic pulmonary fibrosis (posIPF)' is characterized by a radiological pattern of inconsistent usual interstitial pneumonia (UIP) on high-resolution computed tomography (HRCT) scan and a UIP pattern in surgical lung biopsy (SLB). The evidence base to guide treatment for patients with posIPF is lacking; the clinician must choose between observation, treatment with immunomodulatory agents or anti-fibrotic agents. METHODS: To evaluate outcomes of immunomodulatory treatment, a multicentre cohort of 59 posIPF patients treated with prednisone was analysed retrospectively...
December 5, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29204961/patterns-of-convexal-subarachnoid-haemorrhage-clinical-radiological-and-outcome-differences-between-cerebral-amyloid-angiopathy-and-other-causes
#15
Lionel Calviere, Nicolas Raposo, Victor Cuvinciuc, Christophe Cognard, Fabrice Bonneville, Alain Viguier
BACKGROUND: Cerebral amyloid angiopathy (CAA) is a common aetiology of convexal subarachnoid haemorrhage (cSAH) but little is known about its specific characteristics in comparison with cSAH from other causes. In this study we compared patients with CAA vs. non-CAA-related cSAH. METHODS: Retrospective review of baseline and follow-up data of consecutive patients admitted with a symptomatic acute cSAH. RESULTS: Sixty-two patients were included (mean age 66...
December 4, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/29204759/ocular-manifestations-of-igg4-related-disease-in-children-more-common-than-anticipated-review-of-the-literature-and-case-report
#16
REVIEW
Roubini G Smerla, Dimitra Rontogianni, George E Fragoulis
IgG4-related disease (IgG4-RD) is an entity with various clinical manifestations. Histopathologically, it is characterized by lymphoplasmacytic infiltrates enriched in IgG4 (+) plasmacytes and usually fibrosis of the affected tissue. Most of the patients have also increased IgG4 serum levels and they respond to glucocorticosteroids. In children, due to its rare occurrence, IgG4-RD is ill defined. From the published studies, so far, it appears that ocular manifestations are very common in the paediatric population with IgG4-RD...
December 4, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29204734/basic-concepts-in-metal-work-failure-after-metastatic-spine-tumour-surgery
#17
REVIEW
Naresh Kumar, Ravish Patel, Anshuja Charvi Wadhwa, Aravind Kumar, Helena Maria Milavec, Dhiraj Sonawane, Gurpal Singh, Lorin Michael Benneker
PURPOSE: The development of spinal implants marks a watershed in the evolution of metastatic spine tumour surgery (MSTS), which has evolved from standalone decompressive laminectomy to instrumented stabilization and decompression with reconstruction when necessary. Fusion may not be feasible after MSTS due to poor quality of graft host bed along with adjunct chemotherapy and/or radiotherapy postoperatively. With an increase in the survival of patients with spinal tumours, there is a probability of an increase in the rate of implant failure...
December 4, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29204019/histologically-confirmed-intracranial-tumors-managed-at-enugu-nigeria
#18
Chika Anele Ndubuisi, Samuel C Ohaegbulam, Linda U Iroegbu, Mike Ezeali Ekuma, Wilfred C Mezue, Uwadiegwu Alphonsus Erechukwu
Background: There is controversy about the global distribution of intracranial tumors (ICTs). The previous reports from Africa suggested low frequency and different pattern of distribution of brain tumors from what obtains in other continents. The limitations at that time, including paucity of diagnostic facilities and personnel, have improved. Objective: The objective of this study is to analyze the current trend and distribution of histology confirmed brain tumors managed in Enugu, in a decade...
October 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29203201/combat-related-acetabular-fractures-outcomes-of-open-versus-closed-injuries
#19
Richard L Purcell, Michael A Donohue, Sameer K Saxena, Wade T Gordon, Louis L Lewandowski
INTRODUCTION: Since the onset of the Global War on Terror close to 50,000 United States service members have been injured in combat, many of these injuries would have previously been fatal. Among these injuries, open acetabular fractures are at an increased number due to the high percentage of penetrating injuries such as high velocity gunshot wounds and blast injuries. These injuries lead to a greater degree of contamination, and more severe associated injuries. There is a significantly smaller proportion of the classic blunt trauma mechanism typically seen in civilian trauma...
December 1, 2017: Injury
https://www.readbyqxmd.com/read/29201839/trauma-patterns-of-drowning-after-falling-from-bridges-over-han-river
#20
Jung Hwan Lee, Chung Kee Chough, Jae Il Lee
Objective: Recently, the number of patients who fell or jumped from bridges over Han River has rapidly increased. However, the injury patterns and outcomes of these patients have been poorly characterized. The aim of this study was to determine the injury characteristics of these patients. Methods: We reviewed the medical records of all patients who were transferred to the Emergency Room due to jumping or falling from bridges over Han River between 2011 and 2015...
October 2017: Korean Journal of Neurotrauma
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