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Swapnali Sabhapandit, Somasheila I Murthy, Vivek M Singh, Ketaki Gaitonde, Madhumita Gopal, Kerul Marsonia, Shajeera Sajid, Kalpana Babu
PURPOSE: To report the epidemiology of uveitis in two urban centers in South India. METHODS: Case records seen between January 2014 and December 2014 at two tertiary eye centers in South India were retrospectively reviewed. RESULTS: A total of 1123 patients in the study population had uveitis. Anterior uveitis was seen in 48.9%, posterior in 20.5%, intermediate in 17.3%, and panuveitis in 13.3%. Of these cases, 68.4% were acute uveitis. Pediatric uveitis constituted 6...
October 26, 2016: Ocular Immunology and Inflammation
Mark W Bruner, Ian D Boardley, Veronica Allan, Zach Root, Sara Buckham, Chris Forrest, Jean Côté
Social identity - identity formed through membership in groups - may play an important role in regulating intrateam moral behaviour in youth sport (Bruner, M. W., Boardley, I., & Côté, J. (2014). Social identity and prosocial and antisocial behavior in youth sport. Psychology of Sport and Exercise, 15(1), 56-64. doi:10.1016/j.psychsport.2013.09.003). The aim of this study was to qualitatively examine this potential role through stimulated recall interviews with competitive youth-ice-hockey players. Twenty-three players (Mage = 13...
October 13, 2016: Journal of Sports Sciences
Dongyu Liu, Kun Li, Lihong Zhang, Yanfang Lan, Xiaoqiang Wang, Hui Zhang, Lei Wang, Rui Gui, Zhaoqing Han, Wenteng Jang, Suolang Sizhu, Jiakui Li
Bovine ephemeral fever (BEF) is caused by the arthropod-borne bovine ephemeral fever virus (BEFV), which is classified in family Rhabdoviridae and genus Ephemerovirus. However, it is still unclear whether yaks from the Tibetan plateau of China are exposed to BEFV. It is the first time that a survey was conducted to investigate the seroprevalence of BEFV infection in yaks (Bos grunniens) on the Tibetan Plateau of China. A total of 1123 serum samples were collected randomly from yaks from 2012 to 2015 and were assayed for BEFV antibodies by enzyme-linked immunosorbent assay (ELISA)...
October 8, 2016: Tropical Animal Health and Production
Arthur Haffner, Thomas Bräuniger, Dirk Johrendt
The new phosphidosilicates Li2 SiP2 and LiSi2 P3 were synthesized by heating the elements at 1123 K and characterized by single-crystal X-ray diffraction. Li2 SiP2 (I41 /acd, Z=32, a=12.111(1) Å, c=18.658(2) Å) contains two interpenetrating diamond-like tetrahedral networks consisting of corner-sharing T2 supertetrahedra [(SiP4/2 )4 ]. Sphalerite-like interpenetrating networks of uniquely bridged T4 and T5 supertetrahedra make up the complex structure of LiSi2 P3 (I41 /a, Z=100, a=18.4757(3) Å, c=35...
October 17, 2016: Angewandte Chemie
Sabeeh A Baig, M Justin Byron, Marcella H Boynton, Noel T Brewer, Kurt M Ribisl
Federal law now requires FDA to disseminate information on chemicals in cigarette smoke, but it is unclear how best to do so. In a 2 × 2 between-subjects experiment, participants received a message about chemicals in cigarette smoke (e.g., "Cigarette smoke has benzene.") along with an additional randomly assigned messaging strategy: a "found-in" (e.g., "This is found in gasoline."), a health effect (e.g., "This causes heart disease."), both, or neither. Participants were U.S. probability phone samples of 5000 adults and 1123 adolescents, and an online convenience sample of 4130 adults...
September 23, 2016: Journal of Behavioral Medicine
Aaron S Farberg, Adam C Rigel, Darrell S Rigel
The American Academy of Dermatology and dermatologists' themselves, have recommended public education and patient counseling regarding sunscreen. The purpose of this study was to determine US dermatologists' actual sunscreen perceptions as well as their recommendations and personal usage. 540 practicing US dermatologists responded to an online survey that assessed each physician's perception of safety and efficacy of sunscreen, recommendation factors, and personal usage. Dermatologists have an overall positive view of sunscreen...
September 1, 2016: Journal of Drugs in Dermatology: JDD
Andrew Lepp, Jacob E Barkley
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Hsin-An Chang, Wen-Hui Fang, Tieh-Ching Chang, San-Yuan Huang, Chuan-Chia Chang
Neuropeptide Y (NPY) is involved in resilience to stress, and higher vagal (parasympathetic) activity has been associated with greater stress resilience. Thus, we examined whether rs16147, a functional promoter polymorphism (C>T) of the NPY gene, could influence vagal tone during chronic high stress levels. NPY genotyping, chronic psychological stress level measurement (using the Perceived Stress Scale [PSS]), cardiac autonomic function assessment (using short-term heart rate variability [HRV]) were performed in 1123 healthy, drug-free Han Chinese participants who were divided into low- and high-PSS groups...
2016: Scientific Reports
Cristiane Campello Bresani Salvi, Maria Cynthia Braga, José Natal Figueirôa, Malaquias Batista Filho
BACKGROUND: Treatment of maternal iron-deficiency anaemia can reduce risks of prematurity and low birth weight; hence a reliable diagnosis of maternal iron needs is critical. However, erythrocyte indices and serum ferritin have shown a weak correlation with iron status during pregnancy. This study verified the accuracy of those tests to predict the responsiveness to a therapeutic test with oral iron as reference standard for iron deficiency in pregnant women. METHODS: A prospective diagnostic study phase 3 was conducted in a single prenatal care center in Northeast Brazil...
2016: BMC Pregnancy and Childbirth
Lingen Zhang, Zhenming Xu
Many countries have gained benefits through the solar cells industry due to its high efficiency and nonpolluting power generation associated with solar energy. Accordingly, the market of solar cell modules is expanding rapidly in recent decade. However, how to environmentally friendly and effectively recycle waste solar cell modules is seldom concerned. Based on nitrogen pyrolysis and vacuum decomposition, this work can successfully recycle useful organic components, glass, and gallium from solar cell modules...
September 6, 2016: Environmental Science & Technology
Brahmananda Chakraborty, Sharif Kidwai, Lavanya M Ramaniah
A molten salt mixture of lithium fluoride and thorium fluoride (LiF-ThF4) serves as a fuel as well as a coolant in the most sophisticated molten salt reactor (MSR). Here, we report for the first time dynamic correlations, Onsager coefficients, Maxwell-Stefan (MS) diffusivities, and the concentration dependence of density and enthalpy of the molten salt mixture LiF-ThF4 at 1200 K in the composition range of 2-45% ThF4 and also at eutectic composition in the temperature range of 1123-1600 K using Green-Kubo formalism and equilibrium molecular dynamics simulations...
August 18, 2016: Journal of Physical Chemistry. B
Siqin Ye, Min Qian, Bo Zhao, Richard Buchsbaum, Ralph L Sacco, Bruce Levin, Marco R Di Tullio, Douglas L Mann, Patrick M Pullicino, Ronald S Freudenberger, John R Teerlink, J P Mohr, Susan Graham, Arthur J Labovitz, Conrado J Estol, Dirk J Lok, Piotr Ponikowski, Stefan D Anker, Gregory Y H Lip, John L P Thompson, Shunichi Homma
AIMS: The aim of this study was to determine whether the CHA2 DS2 -VASc score can predict adverse outcomes such as death, ischaemic stroke, and major haemorrhage, in patients with systolic heart failure in sinus rhythm. METHODS AND RESULTS: CHA2 DS2 -VASc scores were calculated for 1101 patients randomized to warfarin and 1123 patients randomized to aspirin. Adverse outcomes were defined as death or ischaemic stroke, death alone, ischaemic stroke alone, and major haemorrhage...
October 2016: European Journal of Heart Failure
Erica S Spatz, Adam L Beckman, Yun Wang, Nihar R Desai, Harlan M Krumholz
IMPORTANCE: During the past decade, the incidence and mortality associated with acute myocardial infarction (AMI) in the United States have decreased substantially. However, it is unknown whether these improvements were consistent across communities of different economic status and geographic regions since efforts to improve cardiovascular disease prevention and management may have had variable impact. OBJECTIVE: To determine whether trends in US county-level, risk-standardized AMI hospitalization and mortality rates varied by county-based median income level...
June 1, 2016: JAMA Cardiology
Robert L Findling, James Groark, Karen A Tourian, Sara A Ramaker, Deborah Chiles, Lingfeng Yang, Alice I Nichols
OBJECTIVE: To investigate the safety and pharmacokinetic profile of ascending doses of desvenlafaxine in children and adolescents with major depressive disorder. Assessment of the effect of desvenlafaxine on depression symptoms was exploratory. METHODS: The 8-week, open-label study included an initial 3.5-day inpatient period followed by a 7.5-week outpatient period. Children (7-11 years) received a single desvenlafaxine dose of 10, 25, 50, or 100 mg on day 1; adolescents (12-17 years) received desvenlafaxine 25, 50, 100, or 200 mg/day...
July 18, 2016: Journal of Child and Adolescent Psychopharmacology
Henri Marfin, Sophie Fedrizzi, Sabrina Crépin, Jean-Jacques Parienti, Anne Gimbert, Violaine Blandamour, Alpha Diallo, Gilles Defer, Delphine Bertram, Laure Peyro Saint Paul
Since August 9, 2004, the 2001 European Directive for clinical trials is applied to the French law. Since the 2006 implementing decree amending public health law on biomedical researches, safety data are managed by sponsor vigilant. Competent authorities collect sponsor's data, implement the vigilance system (Article L. 1123-12 of French Health Code) and supervise drastically safety data in clinical research from clinical trial authorization to final report. However, although available to competent authorities, final reports are not addressed to scientific community, who has only access to scientific publications for clinical trials safety data...
June 16, 2016: Thérapie
J Johnson, D A Case, T Yamazaki, S Gusarov, A Kovalenko, T Luchko
Implicit solvent models offer an attractive way to estimate the effects of a solvent environment on the properties of small or large solutes without the complications of explicit simulations. One common test of accuracy is to compute the free energy of transfer from gas to liquid for a variety of small molecules, since many of these values have been measured. Studies of the temperature dependence of these values (i.e. solvation enthalpies and entropies) can provide additional insights into the performance of implicit solvent models...
September 1, 2016: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Kazuto Ohkura, Yuki Kawaguchi, Yohei Tatematsu, Yoshihiro Uto, Hitoshi Hori
BACKGROUND: Protein tyrosine kinases (PTKs) play major roles in signal transduction during cell proliferation and apoptosis. Tyrphostin AG17 was previously shown to be a potent tumor growth inhibitor, while AG17 induced apoptosis and inhibited activity of cyclin-dependent kinase 2. We herein describe the binding features of tyrphostin AG17 analogs, such as TX-1123, with Src kinase (Src-K). MATERIALS AND METHODS: Structural data for Src-K were obtained from a protein data bank (ID=2SRC), and the molecular interactions between Src-K and TX-1123 derivatives were examined...
July 2016: Anticancer Research
Haruka Muto, Ryo Yamamoto, Keisuke Ishii, Reisa Kakubari, Sachi Takaoka, Aki Mabuchi, Nobuaki Mitsuda
OBJECTIVE: Hypertensive disorders in pregnancy are major causes of maternal mortality and morbidity. Although the combined risk assessments of maternal history, blood pressure, uterine artery Doppler, and maternal serum marker seem to be highly predictive of the development of hypertensive disorders, this method is a little complicated to be performed on many low-risk pregnant women. The aim of this study is to evaluate the use of maternal characteristics, and physical findings early in the second trimester, as predictive factors of hypertensive disorders...
June 2016: Taiwanese Journal of Obstetrics & Gynecology
Sara Zanella, Luigina De Leo, Le Nguyen-Ngoc-Quynh, Bo Nguyen-Duy, Tarcisio Not, Mai Tran-Thi-Chi, Son Phung-Duc, Hai Le-Thanh, Cristina Malaventura, Serena Vatta, Fabiana Ziberna, Martina Mazzocco, Stefano Volpato, Lan Phung-Tuyet, Huong Le-Thi-Minh, Caterina Borgna-Pignatti
OBJECTIVE: The prevalence of coeliac disease (CD) in Vietnam is unknown. To fill this void, we assessed the prevalence of serological markers of CD autoimmunity in a population of children in Hanoi. SETTING: The outpatient blood drawing laboratory of the largest paediatric hospital in North Vietnam was used for the study, which was part of an international project of collaboration between Italy and Vietnam. PARTICIPANTS: Children having blood drawn for any reason were included...
2016: BMJ Open
Barbora Papouskova, Martin Bernard, Jakub Ottenschlager, Jindrich Karban, Petr Velisek, Jan Hrbac, Jan Sykora, Jan Storch, Jan Vacek
Cyclopentenediones (CPDs) are compounds with a variety of applications ranging from the preparation of functional polymers to the development of antimicrobial agents, suggesting the potential use of CPDs as novel bioactive compounds or drugs. For this reason, a detailed characterization of CPDs and the development of robust analytical methods for their trace analysis are being sought. Here we focused on the design and synthesis of a library of novelized benzylidene CPD derivatives that were consequently characterized by ultra-high performance liquid chromatography (UHPLC) on-line connected with tandem mass spectrometry (MS/MS)...
September 5, 2016: Journal of Pharmaceutical and Biomedical Analysis
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